1.influence of Qufeng Xuanbi Formula on ICAM-1 of Asthma Guinea Pig
Suofang SHI ; Han WU ; Yiping FAN ;
Journal of Zhejiang Chinese Medical University 2006;0(06):-
[Objective]To discuss the functional mechanism of Qufeng Xuanbi(remove wind and apoplexy)Formula(Pingxiao Heji) on bronchia asthma.[Method]Make bronchia asthma animal model with guinea pig sensitized by egg albumen,treat it with Qufeng Xuanbi Formula,observe the changes of cell adhesion molecular(ICAM-1)in animal plasma.[Result]When experimental guinea pig was attacked by asthma,the ICAM-1 was obviously more than that in normal control group,the formula could markedly lower ICAM-1(95% of the believable zone 20.387~53.834u/ml)(P
2.Investigation and confirmatory factor analysis of information collected with the four diagnostic methods in patients with bronchial asthma
Suofang SHI ; Xiufang LIU ; Zhilin YAN ; Daocheng WANG ; Xiangwen KONG ; Zhencang SHEN ; Qiguang CHEN ; Jie MIN
Journal of Integrative Medicine 2005;3(5):363-5
OBJECTIVE: To investigate the information acquired through the four diagnostic methods of traditional Chinese medicine in patients with bronchial asthma, and to classify the syndrome types. METHODS: Four hundred and thirty patients with bronchial asthma were randomly investigated. The information acquired through the four diagnostic methods was recorded and the database was established by Amos software, and then the data were analyzed by confirmatory factor analysis (CFA). RESULTS: After analyzing the data with 4 factors, 5 factors and 6 factors, we found that the results of CFA with 6 factors were in accordance with clinical practical experience. CONCLUSION: According to the results of CFA with 6 factors and with the standard regression coefficient 0.4 as primary and secondary critical points, the syndromes in patients with bronchial asthma can be classified into 5 types, which are syndromes of cold fluid retained in lung, phlegm-heat obstructing lung, wind-phlegm blocking lung, qi deficiency of lung and kidney and qi deficiency of spleen.