1.Observation of Stent Assisted Coiling for Treatment of Intracranial Saccular Aneurysm Effect
Modern Hospital 2016;16(10):1447-1449
Objective Study of self expandable stent assisted coiling for treatment of intracranial saccular aneurysm effect.Methods Select 2011 April 2013 April in our hospital by self expandable stent assisted coil in the treatment of in-tracranial saccular aneurysms of the 27 patients as the research object , after the occurrence of complications in patients with statistics.And by using the digital subtraction angiography (DSA) under full of carotid and cerebral angiography in patients with tumor total occlusion rates are examined and of patients were the therapeutic effect of three years of follow -up were ob-served.Results The incidence of postoperative complications was low , and the patients were followed up after the tumor to-tal occlusion rate was significantly better than the examination results , and the difference was significant ( P<0.05 ) , with statistical significance .Conclusion The Peng type stent assisted coiling for treatment of intracranial saccular aneurysms has significant effect , safe and reliable .
2.Effects of Liraglutide on Omentin-1 and Insulin Resistance in High-fat Diet Obese Rats
Journal of China Medical University 2015;(12):1129-1131
Objective to investigate the effects of liraglutide on omentin-1 and insulin resistance in high-fat diet rats. Methods Forty male Wi-star rats were randomly divided into four groups,and respectively fed with normal diet(NC group),high-fat diet(HF group),high-fat diet with small doses of liraglutide injected intraperitoneally(HF+Lira 1 group),and high-fat diet with large doses of liraglutide injected intraperitoneally (HF+Lira 2 group). After 16 weeks,the body weight,serum lipid levels,omentin-1 and insulin were measured,and then the insulin resistance in-dex were calculated. Results the body weight,the levels of tG,and the insulin resistance index in HF group were higher than NC group,omentin-1 was lower,and the differences were statistically significant(P < 0.05). tC,LDL-C were elevated,HDL-C was reduced,but there were no statisti-cally differences(P > 0.05). Compared with HF group,the body weight,the levels of tG,and the insulin resistance index in HF+Lira 1 group and HF+Lira 2 group were lower,omentin-1 was higher,the differences were statistically significant(P < 0.05). Furthermore,the effects of HF+Lira 2 group were more pronounced. Conclusion Liraglutide can restrain high-fat diet induced obesity,and improve insulin resistance through elevated the level of omentin-1 in dose-dependent manner.
3.Clinical Observation of Bleeding in Zhongfu on Pulmonary Arterial Hypertension Induced by Chronic Cor Pulmonale
Yu WANG ; Zhenzhen SUO ; Qingquan WANG
Journal of Zhejiang Chinese Medical University 2014;(2):208-209
[Objective]It is to observe the clinical effect of bleeding in Zhongfu on pulmonary arterial hypertension induced by chronic cor pulmonale. [Methods]60 cases of patients with chronic cor pulmonale were randomly divided into two groups. Control group was given standardizing normal drugs , and the treatment group was added with bleeding in Zhongfu on the basis treatment above. Pulmonary artery pressure and index of blood rheology were compared between the two groups after 14 days. [Results]Compared with each other,the difference was significant( P<0.05). Indexes of pulmonary artery and blood rheology were al improved obviously after treatment in both groups, especial y in treatment group( P<0.05). [Conclusion]Combination with bleeding in Zhongfu can more effectively increase the clinical effect, low down pulmonary artery pressure and improve blood viscosity.
4.Effect of ultraviolet C irradiation on expression of transforming growth factor β in wound
Wei SUO ; Xinglin WANG ; Dewen WANG
Chinese Journal of Rehabilitation Theory and Practice 2002;8(1):5-7
ObjectiveTo study the effect of ultraviolet C(UVC) irradiation at different doses on expression of transforming growth factor β(TGF-β) of granulation tissues in wound. MethodsAfter dosing 15mJ/cm2 or 60mJ/cm2 UVC on wound of rats, the expression of TGF-β were observed at both the mRNA level and the protein level by the methods of in situ hybridization and immunohistochemistry respectively. Results At the 7th day after UVC irradiation, the expression of TGF-β in the 15mJ/cm2 group were higher than that in 60mJ/cm2 group and controls (P<0.05)at both the mRNA and the protein level. On the 21st day, the level of TGF-β mRNA in the 60mJ/cm2 group was higher than that in the other two groups(P<0.05).Conclusions At the early stage of wound healing,the treatment of 15mJ/cm2 UVC irradiation promots the expression of TGF-β and might be useful for accelerating wound healing. The level of TGF-β mRNA was up-regulated at the later stage at the dose of 60mJ/cm2 UVC irradiation.
5.Comparison on mineral elements in bone of Sailong and tiger
Yourui SUO ; Baochen ZHANG ; Hanqing WANG
Chinese Traditional and Herbal Drugs 1994;0(04):-
backbone. The existing form of Ca and P in the skeletons of Sailong and tiger was mainly Ca 10(PO 4) 6(OH) 2. Conclusion The mineral element contents in the skeletons of Sailong and tiger bone have the comparability. It shows that the contents of essential trace elements in Sailong bone are prior to those in tiger bone, significantly.
6.Clinical features and related factors of elderly arrhythmia
Xiaoxia SUO ; Qingyuan WANG ; Fuai TANG
Chinese Journal of Primary Medicine and Pharmacy 2013;20(15):2248-2249
Objective To study the clinical characteristics and the related factors of elderly arrhythmia.Methods 658 elderly patients with cardiac arrhythmia who were confirmed by the conventional ECG or Holter were chosen.Their arrhythmia type and related factors were analyzed.Results Among 658 cases of elderly patients,atrial fibrillation accounted for the highest rate(19.0%,241/1 266),followed by ventricular contraction of 17.0% (215/ 1 266).The detection rate of sinus arrhythmia,ventricular arrhythmia was significantly different between ≥ 80 age group and < 80 years old group of elderly patients (P < 0.05).The 658 elderly patients had a total of 976 kinds of underlying disease,every elderly patient had one or more than one underlying disease.The top five underlying diseases were hypertension 18.6% (182/976),coronary heart disease 16.9% (165/976),chronic obstructive pulmonary disease 15.1% (147/976),diabetes 14.3% (140/976),malignant tumors 11.1% (108/976),other underlying disease 24.0% (234/976).In ≥ 80-years-old group,50.8% (123/242) patients complicated with a variety of underlying diseases,which was significantly higher than that of < 80-years-old group 24.5% (102/416) (P < 0.05).Conchluion Elderly patients due to the presence of different levels of underlying diseases and function degradation,prone to a variety of different types of arrhythmias,which should attract enough attention in clinical diagnosis and treatment,early detection and early intervention,in order to improve the quality of life of elderly patients.
7.Characteristics and development trends of new-style field first-aid medical equipment
Zaiping SUO ; Yundou WANG ; Xunqin LIU
Chinese Medical Equipment Journal 1989;0(02):-
This paper presents a general review on characteristics and development trends of new-style field first-aid medical equipment. It shows that first-aid medical equipment has new characteristics involving multi-functions, flexibility, application of advanced technology, etc., and has new development trends such as multiple functions, higher efficiency to be used in war and intellectualized control for self-aid and buddy-aid.
8.Correlation between breast cancer and microsatellite instability
Yonghua YAO ; Quan WANG ; Jian SUO
Journal of Endocrine Surgery 2011;05(3):165-166,178
Objective To investigate the correlation between clinical features of breast cancer and microsatellite instability(MSI).Methods 60 samples of breast cancer were eollected and 5 microsatellite polymorphism loci were selected.MSI analysis Was made after DNA isolation,PCR amplification,electrophoresis and EB staining.Results The rate of MSI was 33.3%in breast cancer and 0%in normal breast tissues.MSI in breast cancer was associated with carcinoma differentiation degree.Conclusion MSI is an early event during breast carcinogenesis and it plays an important role in estimation of malignant degree.
9.Retrospective study of the effect of alimentary tract reconstruction after gastrectomy on the treatment of type 2 diabetes mellitus
Jian SUO ; Yunlei YU ; Quan WANG
Journal of Endocrine Surgery 2009;3(1):35-37
Objective To research the effect of alimentary tract reconstruction after gastrectomy on the treatment of type 2 diabetes mellitus(non-insulin-dependent diabetes mellitus, NIDDM). Methods From January 2005 to January 2008, perioperative blood glucose level and insulin therapy in 24 gastric cancer or periampullary carcinoma patients with non-obesity type 2 diabetes were retrospectively analyzed. These patients underwent different alimentary tract reconstruction, including 8 patients for Billroth I, 10 for standard Whipples operation, 6 for esophageal Roux-en-Y jejunostomy after total gastrectomy. Glucose level and insulin dosage of thease patients were compared. Results In the patients underwent Billroth I operation, change of blood glucose level before and after operation was not significant(P>0.05). The level of blood glucose in patients underwent Whipples operation and total gastrectomy were significant changed 1 and 2 months after the operation (P<0.001). In Billroth I group, 5 patients used insulin to control hyperglycemia preoperatively. After the operation, 2 patents maintained preoperative insulin dosage, 2 had to increase the use of insulin and 1 decreased the insulin dosage. In Whipples group, 6 patients used insulin preoperatively. Interestingly, 4 patents needed less insulin to control hyperglycemia and 2 were free of insulin dependance. In total gastrectomy group, there were 4 patients using insulin to control hyperglycemia. After the operation, 2 patents needed less insulin dosage and 2 stopped using insulin. Conclusions Both Whipples operation and total gastrectomy lead to decreased blood glucose level in NIDDM patients and less need of insulin.The effect of some types of alimentary tract reconstruction after gastrectomy on treatment of type 2 diabetes mellitus is assertive.
10.Selection method for army basic medical equipment
Zaiping SUO ; Yundou WANG ; Xiaofeng ZHANG
Chinese Medical Equipment Journal 2004;0(08):-
A series of indexes are determined and an improved selection method is applied after comparing several evaluating methods on the basis of the characteristics of the army basic medical equipment.Algorithm for quantitatization of indexes,normalization of data,weight of each index and ranking are illuminated systematically.