[Objective]To explore the combined curative effect of the ginkgo leaf and benazepril on the early diabetic nephropathy(DN).[Method]Ninety patients with the early diabetic nephropathy(DN)were randomly divided into single group(n=45,the ginkgo leaf injection 20ml,once a day for 3 months)and combined group(n=45,added benazepril 10mg,once a day for 3 months).The changes in glycosylated hemoglobin(Hba1c) and 24-hour urinary microalbum inuria were observed before and after treatment.[Result]Hba1c remained unchanged throughout the course of the treatment,urinary microalbum inuria decreased in both groups,a more profound reduction was achieved after the combined treatment(P