1.Correlation of Body Composition via Bioelectrical Impedance Analysis and Motor Function and Recovery of Upper Extremity in Patients Undergoing Stroke Rehabilitation
Sunha PARK ; Jaewon KIM ; Youngmin KIM ; Min-Wook KIM
Brain & Neurorehabilitation 2022;15(2):e20-
Bioelectrical impedance analysis (BIA) has been used to investigate the body compositions and predict functional outcomes in patients with stroke, while the role of BIA to predict motor function or recovery in stroke has not been clarified. This study aimed to investigate relationship between body composition measured by BIA and upper limb motor function and recovery. Body compositions (soft tissue lean mass, phase angle, body fat mass and body water) of fifty patients who are admitted to the stroke rehabilitation unit were segmentally analyzed via BIA. The motor recovery of upper extremity (UE) was evaluated via Fugl-Meyer Assessment (UE-FMA) at the time of transfer and discharge. Correlations between body composition and UE-FMA at discharge were analyzed using Spearman correlation coefficient.Multiple regression analysis was used to determine the regression between body composition and motor function and recovery. The Δ Phase angle, the difference of both sides was significantly linearly inversely correlated with UE-FMA at discharge. However, in multiple regression analysis, body compositions including phase angle did not significantly predict motor function at discharge or motor recovery. The Δ Phase angle is related to the severity of upper limb motor function at discharge in subacute stroke patients, and further studies are needed to determine its value as a predictor for motor recovery.
2.Bilateral Cerebral Ptosis in a Patient with Subdural Hemorrhage: a Case Report
Ji Hye KANG ; Sunha PARK ; Young-Ah CHOI
Brain & Neurorehabilitation 2021;14(2):e17-
Although cerebral ptosis is rare, it is commonly associated with unilateral right cerebral hemisphere lesions. We report a case of a 79-year-old woman who presented with bilateral complete ptosis after a traumatic right fronto-temporo-parietal subdural hemorrhage (SDH).Bilateral ptosis was the primary manifestation of the acute right SDH, and the patient had no parenchymal lesion. Her prognosis was good, and she made a complete recovery. Right hemispheric hypoperfusion, as demonstrated on brain perfusion single-photon emission computed tomography, implied that the lateralization of eyelid control was in the right hemisphere, in line with previous reports.
3.Musculocutaneous and Median Neuropathy after MiraDry Ⓡ Procedure for Axillary Hyperhidrosis
Youngmin KIM ; Mi-Jeong YOON ; Sunha PARK ; Min Wook KIM
Clinical Pain 2021;20(2):135-140
MiraDryⓇ , a microwave thermolysis device, is comparably new non-surgical agent in the field of eradication of sweat glands for treating axillary hyperhidrosis and osmidrosis. So far, altered sensation, swelling, and compensatory sweating are widely known as adverse effects of MiraDryⓇ . Of the few reported MiraDryⓇ -induced neuropathy cases, median and ulnar neuropathies are common. Although, one case has described radial nerve and posterior cord damage with maximized stimulation intensity, musculocutaneous nerve damage induced by MiraDryⓇ has not been reported. Here, we report a case of a 30-year-old woman experiencing left hand weakness after receiving MiraDryⓇ at a local dermatology clinic. Left brachial plexopathy, mainly involving the median nerve and the musculocutaneous nerve with partial axonotmesis, was confirmed by electrodiagnostic studies.Ultrasound evaluation showed corresponding results. This is the first case report of the musculocutaneous neuropathy by MiraDry>Ⓡ
4.A Case of Esophageal Lymphoepithelioma-like Carcinoma.
Sunha BAHNG ; Jun Haeng LEE ; Eun Kyoung KIM ; Sung Bum PARK ; Silvia PARK ; Kyoung Mee KIM
Korean Journal of Gastrointestinal Endoscopy 2010;41(1):41-44
Lymphoepithelioma-like carcinoma (LELC) of the esophagus is an extremely rare tumor and the prognosis is favorable. We present here a case an esophageal LELC that showed no definite progression for 5 years. An esophageal tumor was found during screening endoscopy for a 72-year-old asymptomatic Korean woman. At first the histology showed no abnormal findings. No treatment was done for the lesion. Five years later, a follow-up endoscopy showed the same tumor in the esophagus. The size and shape of the esophageal tumor seemed unchanged during the follow-up. The lesion was a round elevated lesion that measured approximately 2.5 cm in the lower esophagus. The covering mucosa looked smooth, but there were erosions on top of the tumor. Biopsy showed an undifferentiated carcinoma associated with a dense lymphocytic and plasma cell infiltration, which are typical findings of LELC.
Aged
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Biopsy
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Carcinoma
;
Endoscopy
;
Esophageal Neoplasms
;
Esophagus
;
Female
;
Follow-Up Studies
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Humans
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Mass Screening
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Mucous Membrane
;
Plasma Cells
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Prognosis
5.A Huge Mediastinal Organizing Hematoma Causing Reversal of Atrial Septal Defect Shunt Flow.
Eun Kyoung KIM ; Sang Chol LEE ; Sung Bum PARK ; Silvia PARK ; Sunha BAHNG ; Yeon Hyeon CHOE ; Kiick SUNG
Korean Circulation Journal 2011;41(2):97-100
We report a case of a 46-year-old woman who presented with subacute exertional dyspnea and severe hypoxia. A large cystic mass compressing the right side of the heart along with right-to-left atrial shunt flow through an alleged atrial septal defect (ASD) were detected on echocardiography. CT scan of the chest and MRI of the heart revealed a loculated cystic mediastinal mass with hemorrhage measuring 5.5x8 cm compressing the right atrium and ventricle. The patient underwent cyst resection and primary closure of the ASD. This report illustrates a case of an unusual symptomatic pericardial mass compressing the right atrium and ventricle in a patient with an secundum ASD.
Anoxia
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Dyspnea
;
Echocardiography
;
Female
;
Heart
;
Heart Atria
;
Heart Septal Defects, Atrial
;
Hematoma
;
Hemorrhage
;
Humans
;
Mediastinal Cyst
;
Middle Aged
;
Thorax
6.A Huge Mediastinal Organizing Hematoma Causing Reversal of Atrial Septal Defect Shunt Flow.
Eun Kyoung KIM ; Sang Chol LEE ; Sung Bum PARK ; Silvia PARK ; Sunha BAHNG ; Yeon Hyeon CHOE ; Kiick SUNG
Korean Circulation Journal 2011;41(2):97-100
We report a case of a 46-year-old woman who presented with subacute exertional dyspnea and severe hypoxia. A large cystic mass compressing the right side of the heart along with right-to-left atrial shunt flow through an alleged atrial septal defect (ASD) were detected on echocardiography. CT scan of the chest and MRI of the heart revealed a loculated cystic mediastinal mass with hemorrhage measuring 5.5x8 cm compressing the right atrium and ventricle. The patient underwent cyst resection and primary closure of the ASD. This report illustrates a case of an unusual symptomatic pericardial mass compressing the right atrium and ventricle in a patient with an secundum ASD.
Anoxia
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Dyspnea
;
Echocardiography
;
Female
;
Heart
;
Heart Atria
;
Heart Septal Defects, Atrial
;
Hematoma
;
Hemorrhage
;
Humans
;
Mediastinal Cyst
;
Middle Aged
;
Thorax
7.Low-Dose Bisphenol A Increases Bile Duct Proliferation in Juvenile Rats: A Possible Evidence for Risk of Liver Cancer in the Exposed Population?.
Ji Seong JEONG ; Ki Taek NAM ; Buhyun LEE ; Aryo Dimas PAMUNGKAS ; Daeun SONG ; Minjeong KIM ; Wook Joon YU ; Jinsoo LEE ; Sunha JEE ; Youngja H PARK ; Kyung Min LIM
Biomolecules & Therapeutics 2017;25(5):545-552
Increasing concern is being given to the association between risk of cancer and exposure to low-dose bisphenol A (BPA), especially in young-aged population. In this study, we investigated the effects of repeated oral treatment of low to high dose BPA in juvenile Sprague-Dawley rats. Exposing juvenile rats to BPA (0, 0.5, 5, 50, and 250 mg/kg oral gavage) from post-natal day 9 for 90 days resulted in higher food intakes and increased body weights in biphasic dose-effect relationship. Male mammary glands were atrophied at high dose, which coincided with sexual pre-maturation of females. Notably, proliferative changes with altered cell foci and focal inflammation were observed around bile ducts in the liver of all BPA-dosed groups in males, which achieved statistical significance from 0.5 mg/kg (ANOVA, Dunnett’s test, p<0.05). Toxicokinetic analysis revealed that systemic exposure to BPA was greater at early age (e.g., 210-fold in C(max), and 26-fold in AUC at 50 mg/kg in male on day 1 over day 90) and in females (e.g., 4-fold in C(max) and 1.6-fold in AUC at 50 mg/kg vs. male on day 1), which might have stemmed from either age- or gender-dependent differences in metabolic capacity. These results may serve as evidence for the association between risk of cancer and exposure to low-dose BPA, especially in young children, as well as for varying toxicity of xenobiotics in different age and gender groups.
Animals
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Area Under Curve
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Bile Ducts*
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Bile*
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Body Weight
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Child
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Female
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Humans
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Inflammation
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Liver Neoplasms*
;
Liver*
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Male
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Mammary Glands, Human
;
Rats*
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Rats, Sprague-Dawley
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Toxicokinetics
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Xenobiotics