1.Age-Related Changes in the Prevalence of Osteoporosis according to Gender and Skeletal Site: The Korea National Health and Nutrition Examination Survey 2008-2010.
Jongseok LEE ; Sungwha LEE ; Sungok JANG ; Ohk Hyun RYU
Endocrinology and Metabolism 2013;28(3):180-191
BACKGROUND: The incidence of osteoporosis and its related fractures are expected to increase significantly in the rapidly aging Korean population. Reliable data on the prevalence of this disease is essential for treatment planning. However, sparse data on Korean patients is available. METHODS: We analyzed data from the Korea National Health and Nutrition Examination Survey (KNHANES) 2008 to 2010. Bone mineral density (BMD) was measured at the femoral neck and lumbar spine using dual-energy X-ray absorptiometry. Osteopenia and osteoporosis were diagnosed according to the World Health Organization T-score criteria. We analyzed the BMD data of 17,208 people (men, 7,837; women, 9,368). RESULTS: The adjusted prevalence of osteoporosis was 7.8% in men versus 37.0% in women. No significant difference was observed in the prevalence of osteopenia between genders (men, 47.0%; women, 48.7%). The prevalence of osteoporosis in men in their 50s was 4.0%, in their 60s was 7.2%, in their 70s was 15.1%, and in their 80s was 26.7%. The figures in women were 15.2%, 36.5%, 62.7%, and 85.8%, respectively. The age group with the maximal BMD differed between genders. In the men, 20s had the highest value in all the skeletal sites. However, in the women, the maximal BMD in the femoral neck, lumbar spine, and the total hip was observed in their 20s, 30s, and 40s, respectively. The onset age of osteoporosis differed between genders. Osteoporosis in the femoral neck began at 55 years in the women and at 60 years in the men. CONCLUSION: The prevalence of osteoporosis in Korea was significantly high. In addition, the age-related changes in the prevalence of osteoporosis differed according to gender and skeletal site.
Absorptiometry, Photon
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Age of Onset
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Aging
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Bone Density
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Bone Diseases, Metabolic
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Female
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Femur Neck
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Hip
;
Humans
;
Incidence
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Korea
;
Male
;
Nutrition Surveys
;
Osteoporosis
;
Prevalence
;
Spine
;
World Health Organization
2.The effect of high-dose vitamin D supplementation on insulin resistance and arterial stiffness in patients with type 2 diabetes.
Ohk Hyun RYU ; Wankyo CHUNG ; Sungwha LEE ; Kyung Soon HONG ; Moon Gi CHOI ; Hyung Joon YOO
The Korean Journal of Internal Medicine 2014;29(5):620-629
BACKGROUND/AIMS: Recent epidemiological studies revealed a striking inverse relationship between vitamin D levels, glucose intolerance/insulin resistance (IR), and cardiovascular disease. However, few interventional studies have evaluated the effect of vitamin D supplementation on cardiovascular risk, such as IR and arterial stiffness, in diabetes. We investigated the role of vitamin D supplementation on cardiovascular risk in type 2 diabetes patients, including metabolic parameters, IR, and arterial stiffness. METHODS: We enrolled patients who were taking antidiabetic medications or managed their diabetes using lifestyle changes. We excluded patients who were taking vitamin D or calcium supplements. We randomized participants into the vitamin D group (cholecalciferol 2,000 IU/day + calcium 200 mg/day, n = 40) or the placebo group (calcium 200 mg/day, n = 41). We compared their IR (homeostasis model of assessment [HOMA]-IR) and arterial stiffness (brachial-ankle pulse wave velocity and radial augmentation index) before and after 24 weeks of intervention. RESULTS: The baseline characteristics of the two groups were similar. A total of 62 participants (placebo, 30; vitamin D, 32) completed the study protocol. At the end of the study period, the 25-hydroxyvitamin D [25(OH)D] levels were significantly higher in the vitamin D group than in the placebo group (35.4 +/- 8.5 ng/mL vs. 18.4 +/- 7.3 ng/mL, p < 0.001). There was no difference in HOMA-IR or changes in arterial stiffness (placebo, 21, vitamin D, 24) between the groups. CONCLUSIONS: Our data suggest that high-dose vitamin D supplementation might be effective in terms of elevating 25(OH)D levels. However, we identified no beneficial effects on cardiovascular risk in type 2 diabetes, including IR and arterial stiffness.
Calcium, Dietary/administration & dosage
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Cholecalciferol/*administration & dosage
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Diabetes Mellitus, Type 2/complications/*drug therapy/physiopathology
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Double-Blind Method
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Female
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Humans
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*Insulin Resistance
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Male
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Middle Aged
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Prospective Studies
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Vascular Stiffness/*drug effects
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Vitamin D/analogs & derivatives/blood
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Vitamin D Deficiency/blood/complications/drug therapy
3.Extension of a Scapular Fracture into the Glenoid Cavity after Low-voltage Electric Shock.
Hyungbin KIM ; Sangkyoon HAN ; Sungwook PARK ; Sungwha LEE ; Soonchang PARK ; Youngmo CHO ; Seokran YEOM ; Yongin KIM ; Munki MIN ; Maengreal PARK ; Jiho RYU
Journal of the Korean Society of Emergency Medicine 2017;28(1):138-140
We, herein, present a patient with no history of trauma who developed shoulder pain after undergoing low-voltage electric shock. According to the computed tomography, there was a multi-segmental fracture that extended into the glenoid cavity of the left scapula. A good outcome was obtained after open reduction and internal fixation. Emergency physicians should be aware of the possibility of scapular fracture extending into the glenoid cavity, especially in patients with shoulder pain after electrical injury.
Electric Injuries
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Emergencies
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Glenoid Cavity*
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Humans
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Scapula
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Shock*
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Shoulder Pain