1.A Case of Deep Vein Thrombosis Associated with Pulmonary and Renal Thromboembolism.
Byungsam LEE ; Oksik SHIN ; Gyuchang SHIN ; Hongsu JUNG ; Taeho JUNG ; Jaeguen JANG ; Sungrok KIM ; Yongkoo OH
Korean Circulation Journal 1993;23(5):754-760
The deep vein thrombosis had been described as the reaction of vascular inflammatory change by John Hunter in 1773, and Virchow described the pathophysiology of etiologic factors for the first time in 1856. Deep Vein thrombosis and pulmonary embolism is common disease in the North American and European countries. It was reported that deep Vein thrombosis and pulmonary embolism were associated with 300,000 to 600,000 hospitalizations for each year and that as many as 50,000 individuals die each year as a result of pulmonary embolism in the United States. In Korea, deep vein thrombosis is uncommon, complicating pulmonary embolism & renal thromboembolism are also rare, and many cases had not specific history & precipitating factor. The report is for one case of deep vein thrombosis associated with pulmonary & renal thromboembolism, who was 34-years-old, admitted to Masan Koryo hospital because of pain and edema in left lower extremity, had not specific history & precipitating factor. The thrombosis(or thromboembolism) involed his left lung & kidney, and the patient present with severe swelling of affected limb and oliguria. He underwent leg elevation under absolute bed rest and anticoagulant therapy. The significant improvement was done under medical treatment. We report one case of deep vein thrombosis with a brief of literatures.
Bed Rest
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Edema
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Extremities
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Hospitalization
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Humans
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Kidney
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Korea
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Leg
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Lower Extremity
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Lung
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Oliguria
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Precipitating Factors
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Pulmonary Embolism
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Thromboembolism*
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United States
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Venous Thrombosis*
2.Domino living donor liver transplantation of familial amyloid polyneuropathy patient - A case report -
Sungrok CHA ; Jiwon KIM ; Soo Joo CHOI ; Gaab-Soo KIM
Anesthesia and Pain Medicine 2020;15(4):472-477
Background:
Familial amyloid polyneuropathy (FAP) is caused by mutation in a gene transcribing transport protein produced mainly by the liver. Liver transplantation is required to stop FAP progression, but the pathology causes anesthetic management challenges.Case: We report a case of domino living donor liver transplantation in an FAP patient. No intraoperative events occurred; however, during postoperative day 1 in the intensive care unit (ICU), the FAP patient underwent multiple cardiopulmonary resuscitation (CPR) sessions due to pulseless electrical activity following a sudden drop in blood pressure and ventricular tachycardia. Despite ICU management, the patient died after the third CPR session.
Conclusions
Various anesthetic management techniques should be considered for FAP patients. Anesthetic management was carefully assessed with the use of isoflurane, isoproterenol, and an external patch. The cause of deterioration in the ICU is unclear, but further investigation is needed to prevent and better manage postoperative morbidity and mortality.
3.Perinatal Prognostic Factors for Congenital Diaphragmatic Hernia: A Korean Single-Center Study
Sungrok JEON ; Mun Hui JEONG ; Seong Hee JEONG ; Su Jeong PARK ; Narae LEE ; Mi-Hye BAE ; Kyung-Hee PARK ; Shin-Yun BYUN ; Soo-Hong KIM ; Yong-Hoon CHO ; Choongrak KIM ; Young Mi HAN
Neonatal Medicine 2022;29(2):76-83
Purpose:
This study aimed to identify prognostic factors based on treatment outcomes for congenital diaphragmatic hernia (CDH) at a single-center and to identify factors that may improve these outcomes.
Methods:
Thirty-five neonates diagnosed with CDH between January 2011 and December 2021 were retrospectively analyzed. Pre- and postnatal factors were correlated and analyzed with postnatal clinical outcomes to determine the prognostic factors. Highest oxygenation index (OI) within 24 hours of birth was also calculated. Treatment strategy and outcome analysis of published literatures were also performed.
Results:
Overall survival rate of this cohort was 60%. Four patients were unable to undergo anesthesia and/or surgery. Three patients who commenced extracorporeal membrane oxygenation (ECMO) post-surgery were non-survivors. Compared to the survivor group, the non-survivor group had a significantly higher occurrence of pneumothorax on the first day, need for high-frequency ventilator and inhaled nitric oxide use, and high OI within the first 24 hours. The non-survivor group showed an early trend towards the surgery timing and a greater number of patch closures. Area under the receiver operating characteristic curve was 0.878 with a sensitivity of 76.2% and specificity of 92.9% at an OI cutoff value of 7.75.
Conclusion
OI within 24 hours is a valuable predictor of survival. It is expected that the application of ECMO based on OI monitoring may help improve the opportunity for surgical repair, as well as the prognosis of CDH patients.