Background: This study was conducted to compare the job stress, resilience, and burnout levels of small and medium-sized hospital nurses working at National safety hospitals and coronavirus disease-19 (COVID-19) dedicated hospitals, and to identify influencing factors on burnout. Methods: This study was a cross-sectional study and research participants were nurses at small and medium-sized hospitals working at National safety hospitals and COVID-19 dedicated hospitals. Data from 292 nurses collected using a structured questionnaires from April 1 to 30, 2020 were used. Data was analyzed using multiple regression analyses. Results: As a result of this study, there was a significant difference in stress on job demand and job resources of nurses working at National safety hospital type B and COVID-19 dedicated Hospital. There was no difference in job stress and resilience of nurses among types of hospitals. As a result of multiple regression, stress to job demands and resilience were factors influencing the level of exhaustion of nurses. Stress to job demands and job resources and resilience were factors influencing the level of disengagement of nurses. Conclusions Considering the results of this study, it is suggested to introduce strategies to reduce nurses’ job stress and burnout caused by COVID-19.

No abstract available.
Nipples*

Traditional hyperthermia involves increasing the temperature at the tumor site to above 39 ℃, inducing death in cancer cells. Although hyperthermia is an effective cancer treatment, its clinical application has decreased due to potential complications, including damage to surrounding normal tissue. In recent years, modulated electro-hyperthermia (mEHT) has emerged as an effective and safe treatment modality. mEHT selectively heats tumor cells to 42–43 °C, while reducing the average temperature in the treatment area, including the surrounding normal tissue, compared to conventional methods. Additionally, mEHT may be used in combination with systemic chemotherapy and radiation therapy in tumor treatment, providing a synergistic effect to increase efficacy. As chemotherapy and radiation therapy technologies advance, the application of combined mEHT may improve clinical outcomes. In this study, we review and discuss reports on the clinical outcomes of mEHT combined with chemotherapy and/or radiation therapy, which are established anticancer treatments.

This study was undertaken to evaluate the in vitro activities of arbekacin-based combination regimens against vancomycin hetero-intermediate Staphylococcus aureus (hetero-VISA). Combinations of arbekacin with vancomycin, rifampin, ampicillin-sulbactam, teicoplanin, or quinipristin-dalfopristin against seven hetero-VISA strains and two methicillin-resistant S. aureus strains were evaluated by the time-kill assay. The combinations of arbekacin with vancomycin, teicoplanin, or ampicillinsulbactam showed the synergistic interaction against hetero-VISA strains. Data suggest that these arbekacin-based combination regimens may be useful candidates for treatment options of hetero-VISA infections.
Virginiamycin/administration & dosage ; Vancomycin/*administration & dosage ; Teicoplanin/administration & dosage ; Sulbactam/administration & dosage ; Staphylococcus aureus/*drug effects/isolation & purification ; Staphylococcal Infections/drug therapy/microbiology ; Microbial Sensitivity Tests ; Methicillin Resistance ; Humans ; Drug Synergism ; Drug Resistance, Bacterial ; Dibekacin/administration & dosage/*analogs & derivatives ; Anti-Bacterial Agents/*administration & dosage ; Ampicillin/administration & dosage ; Aminoglycosides/*administration & dosage

PURPOSE: To obtain basic information for studies of male sexual dysfunction, we investigated the prevalence and the risk factors of erectile dysfunction(ED) in Korean young men via an Internet survey. MATERIALS AND METHODS: In June 2006, 23594 subjects aged from 20 to 59, who had registered with an internet research company, were asked to join our study if they had had stable sexual activities more than once a month for the past 6 months. Questions covered demographic characteristics, sexual life, International Index of Erectile Function(IIEF), and International Prostatic Symptom Score(IPSS). RESULTS: A total of 601 subjects completed the questionnaires. The prevalence of self-reported ED was 6.7%. The proportion of men with self-reported ED was 3.7% in the 20-29 age group, 6.0% in the 30-39 age group, and 9.5% in the 40-49 age group. The overall prevalence of ED assessed by IIEF-EF domain score of < or = 25 was 41.0%. We found a statistically significant correlation between men with self-reported ED and lower IIEF-EF domain scores. Self-reported ED was significantly associated with aging, smoking, lower education, and lower urinary tract symptoms (LUTS). Lower IIEF-EF domain scores were correlated with higher IPSS total, voiding and storage scores. CONCLUSIONS: ED in Korean young men is common and closely associated with LUTS. An Internet survey requires less man power, less time, and less research funds than classical survey methods such as mail or interview surveys. These study results will be useful as basic data for future studies of young Korean men's sexual function
Aging ; Surveys and Questionnaires ; Education ; Erectile Dysfunction* ; Financial Management ; Humans ; Internet ; Lower Urinary Tract Symptoms ; Male ; Multiple Endocrine Neoplasia Type 1 ; Postal Service ; Prevalence* ; Risk Factors* ; Sexual Behavior ; Smoke ; Smoking

PURPOSE: To obtain basic information for studies of male sexual dysfunction, we investigated the prevalence and the risk factors of erectile dysfunction(ED) in Korean young men via an Internet survey. MATERIALS AND METHODS: In June 2006, 23594 subjects aged from 20 to 59, who had registered with an internet research company, were asked to join our study if they had had stable sexual activities more than once a month for the past 6 months. Questions covered demographic characteristics, sexual life, International Index of Erectile Function(IIEF), and International Prostatic Symptom Score(IPSS). RESULTS: A total of 601 subjects completed the questionnaires. The prevalence of self-reported ED was 6.7%. The proportion of men with self-reported ED was 3.7% in the 20-29 age group, 6.0% in the 30-39 age group, and 9.5% in the 40-49 age group. The overall prevalence of ED assessed by IIEF-EF domain score of < or = 25 was 41.0%. We found a statistically significant correlation between men with self-reported ED and lower IIEF-EF domain scores. Self-reported ED was significantly associated with aging, smoking, lower education, and lower urinary tract symptoms (LUTS). Lower IIEF-EF domain scores were correlated with higher IPSS total, voiding and storage scores. CONCLUSIONS: ED in Korean young men is common and closely associated with LUTS. An Internet survey requires less man power, less time, and less research funds than classical survey methods such as mail or interview surveys. These study results will be useful as basic data for future studies of young Korean men's sexual function
Aging ; Surveys and Questionnaires ; Education ; Erectile Dysfunction* ; Financial Management ; Humans ; Internet ; Lower Urinary Tract Symptoms ; Male ; Multiple Endocrine Neoplasia Type 1 ; Postal Service ; Prevalence* ; Risk Factors* ; Sexual Behavior ; Smoke ; Smoking

No abstract available.
Eosinophils* ; Folliculitis* ; Humans ; Infant

No abstract available.
Acupuncture ; Foreign Bodies ; Granuloma, Foreign-Body ; Leprosy ; Leprosy, Lepromatous

The posttransplantation lymphoproliferative disorders (PTLD) are not rare complications of solid organ transplants. The incidence varies with the type of transplantation and the nature and intensity of the immunosuppressive regimens. PTLDs are unique in that they have a predilection for extranodal sites, a strong and probably causal association with Ebstein-Barr virus infection, and a poor response to the cytolytic chemotherapeutic or irradiation regimens used for treatment of malignant lymphoma. The outcomes of treatment have been disappointing, with mortality from PTLD or related complications of over 50% of patients. We experienced two cases of PTLDs in liver transplant recipients presenting with liver mass and intraabdominal lymphadenopathy. PTLDs were diagnosed by autopsy and a liver biopsy. In the case diagnosed by a liver biopsy, EBV was detected by in situ hybridization. Despite reduction of immunosuppression and conservative management, both patients died.
Autopsy ; Biopsy ; Herpesvirus 4, Human ; Humans ; Immunosuppression ; In Situ Hybridization ; Incidence ; Liver Transplantation* ; Liver* ; Lymphatic Diseases ; Lymphoma ; Lymphoproliferative Disorders* ; Mortality ; Transplantation ; Transplants

Granuloma annulare is a benign granulomatous skin disease, clinically characterized by dermal papules tending to form annular shapes. Granuloma annulare is classified into localized, generalized, subcutaneous, and perforating types. Localized granuloma annulare is likely to resolve spontaneously, while generalized granuloma annulare usually takes a chronic course. Topical steroids, phototherapy, isotretinoin, dapsone, hydroxychloroquine, and other various treatments have been proposed, but some cases have been resistant to all of those treatment modalities. We experienced 3 cases of generalized granuloma annulare demonstrating a recalcitrant course that were successfully treated with methotrexate and propose that methotrexate may be an effective option for recalcitrant generalized granuloma annulare treatment.
Dapsone ; Granuloma Annulare* ; Granuloma* ; Hydroxychloroquine ; Isotretinoin ; Methotrexate* ; Phototherapy ; Skin Diseases ; Steroids