1.A very small sinus venosus type of atrial septal defect: A rare but curable cause of recurrent stroke
Seongheon Kim ; Sung-Min Park ; Se-Min Ryu ; Dong Ryeol Ryu
Neurology Asia 2015;20(3):283-285
Sinus venosus is a rare cardiac defect, which may lead to an interatrial shunt. Diagnosis on
echocardiography may be difficult requiring an evaluation by a board-certified cardiologist.
We report a case of a 41 year-old male who presented with recurrent episodes of hemiparesis (first left
sided, second right sided). Surgical correction of sinus venosus led to resolution of his symptoms.
Heart Septal Defects, Atrial
2.Recurrent Tetraplegia in Mixed Type Neurocysticercosis: A case report.
Ji Hoon KIM ; Sung Ryeol JU ; Jae Young HAN ; In Sung CHOI ; Sam Gyu LEE ; Sung Man ROWE
Journal of the Korean Academy of Rehabilitation Medicine 2003;27(4):617-621
Neurocysticercosis is the most common parasitic disease of the central nervous system. Generally, the spinal cord involvement of neurocysticercosis is very rare. We experienced a 52-year-old female patient presented with tetraplegia. She was diagnosed as mixed type neurocysticercosis involving brain parenchyma, ventricle and cervical spinal cord. She underwent an operation of intradural mass removal with cervical laminectomy. In spite of gradual improvement in activities of daily livings, muscle power and sensation, she revealed the fluctuation of mental status and tetraplegia, possibly associated with perilesional inflammation, twice during the period of admission. So, we administered prednisolone 20 mg and albendazole 800 mg a day for a week per event and then her mental status and aggravated tetraplegia were improved. After comprehensive rehabilitation for 4 months, her ASIA impairment scale changed from ASIA C to ASIA D with the improvement of modified Bathel index, Functional independence measure and Mini-mental status examination scores.
Albendazole
;
Asia
;
Brain
;
Central Nervous System
;
Female
;
Humans
;
Inflammation
;
Laminectomy
;
Middle Aged
;
Neurocysticercosis*
;
Parasitic Diseases
;
Prednisolone
;
Quadriplegia*
;
Rehabilitation
;
Sensation
;
Spinal Cord
3.The Clinical Utility of Hand Sympathetic Skin Response in Bell's Palsy.
Seung Wook CHEON ; Sung Ryeol JU ; Kyong Ju KANG ; In Sung CHOI ; Jae Hyung KIM ; Sam Gyu LEE
Journal of the Korean Academy of Rehabilitation Medicine 2004;28(6):574-578
OBJECTIVE: To investigate the correlation between the severity of paralysis and hand sympathetic skin response (SSR) in patients with Bell's palsy and to evaluate the clinical utility of hand SSR as a predicting factor of prognosis. METHOD: Twenty patients with Bell's palsy and twenty normal controls were recruited. The severity of paralysis was graded according to House-Brackmann Facial Grading Scale (H-B FGS), and percent degeneration of Nasalis was determined by Facial Nerve Conduction Study (FNCS). RESULTS: The difference of hand SSR amplitude between affected and unaffected side was significant (p<0.05). There was significant correlation between H-B FGS and the difference of hand SSR amplitude (p<0.05). There was significant correlation between percent degeneration and the difference of hand SSR amplitude (p<0.05). There were significant correlations between the difference of hand SSR amplitude at 5 days and percent degeneration at 9 and 14 days (p=0.026, p=0.001). CONCLUSION: The difference of hand SSR amplitude between affected and unaffected side was useful for the indication of the severity of paralysis. And, hand SSR would be useful for an early prognostic predictor in Bell's palsy.
Bell Palsy*
;
Facial Nerve
;
Hand*
;
Humans
;
Paralysis
;
Prognosis
;
Skin*
4.The Clinical Significance and Prognosis of Korean Young Age (younger or 35 year old) onset Breast Cancer.
Youn Ki MIN ; Nam Ryeol KIM ; Sung Jin CHO ; Aeree KIM ; Jeoung Won BAE ; Bum Hwan KOO
Journal of Korean Breast Cancer Society 2001;4(1):74-79
PURPOSE: Generally, young age onset malignancies show worse prognosis. But is "young age onset" a single prognostic factor for breast cancer, has been controversial. The incidence of breast cancer according to age is different by region and races. This study purposed to know the incidence of breast cancer in younger or 35 year old (below Young age group) and its clinical characteristics, prognosis, and difference with older age onset breast cancer. METHODS: A retrospective study of consecutive 545 breast cancer patients who had been treated by our hospital from 1990 to 1999, was carried out. We investigated the ratio of 35 year old or younger breast cancer patients, age of menarche, TNM stage, histologic grades, hormone receptor status, survival rates. And compared it with counter age (>35) group's. The significances of differences were evaluated using Student's-t test or chi-square test by variable type. Analysis were performed using SPSS software. RESULTS: Younger age group patients were 62 (11.3%) among them, showed earlier menarche, worse histologic differentiation, and lower mammographic detection rate than counter group (p<0.05). There were no difference in TNM stage distribution, hormone receptor expression status according to age group (p>0.05). Young age group's 5 year overall and disease free survival rates were 83+/-5% and 58+/-8%, both were lower than counter group's 89+/-2% and 74+/-3% (p<0.05). Also age adjusted overall and disease free survival rates were worse than counter age group's. CONCLUSION:Younger age group shows worse survival rates, have poor prognostic factors and show early relapsing rate than older age group. So we can consider "young age onset" as a poor prognostic factor in breast cancer.
Adult
;
Breast Neoplasms*
;
Breast*
;
Continental Population Groups
;
Disease-Free Survival
;
Female
;
Humans
;
Incidence
;
Menarche
;
Prognosis*
;
Retrospective Studies
;
Survival Rate
5.Mutagenic Assessment of Olmesartan Cilexetil by Bacterial Mutation Assay.
Ji Won KIM ; Ilyoung AHN ; Sung Ha RYU ; Hong Ryeol JEON ; Bong Sang LEE ; Kyu Bong KIM
Toxicological Research 2013;29(3):217-219
Hypertension is a serious health problem due to high frequency and concomitant other diseases including cardiovascular and renal dysfunction. Olmesartan cilexetil is a new antihypertensive drug associated with angiotensin II receptor antagonist. This study was conducted to evaluate the mutagenicity of olmesartan cilexetil by bacterial reverse mutation test using Salmonella typhimurium (TA100, TA1535, TA98, and TA1537) and Escherichia coli (WP2 uvrA). At the concentrations of 0, 62, 185, 556, 1667, and 5000 microg/plate, olmesartan cilexetil was negative in both Salmonella typhimurium and Escherichia coli regardless of presence or absence of metabolic activation system (S9 mix). These results demonstrate that olmesartan cilexetil does not induce bacterial reverse mutation.
Biotransformation
;
Escherichia coli
;
Hypertension
;
Imidazoles
;
Receptors, Angiotensin
;
Salmonella typhimurium
;
Tetrazoles
6.The effect of diabetes on 4-year changes of hearing thresholds in male workers exposed to noise in a single company: a longitudinal study
Dae Yun KIM ; A Ram KIM ; Joo Hyun SUNG ; Choong Ryeol LEE ; Jiho LEE
Annals of Occupational and Environmental Medicine 2019;31(1):e11-
BACKGROUND: Recently, several studies have assessed the association between diabetes and hearing impairment. However, the effect of diabetes on hearing impairment is not well known in diabetic patients exposed to noise, a typical cause of hearing impairment. The aim of this study is to longitudinally analyze the effect of diabetes on hearing impairment in workers exposed to similar noise levels from 2013 to 2017 who had experienced little change in their working conditions. METHODS: The study subjects included 2,087 male workers exposed to noise in a single company and who underwent health examinations at the same hospital in Ulsan city in 2013 and 2017. Hearing impairment was defined that a pure-tone average of pure-tone audiometry (PTA) thresholds at 1,000, 2,000, 3,000, and 4,000 Hz was 25 dB and over in both ears. Statistical analyses were conducted using χ2 tests, ANOVA, and Cox proportional hazard models. We analyzed covariates that might affect hearing impairment, including age; working period; levels of total cholesterol, triglyceride, and serum creatinine; smoking and alcohol history; and noise level. RESULTS: The average PTA thresholds and their average changes between 2013 and 2017 were significant in the diabetes mellitus (DM) group than those in the normal and impaired fasting glucose group. Among the subjects with the same status of fasting glucose group in 2013 and 2017, the adjusted hazard ratios for incident hearing impairment among those in the DM group compared to normal group were 3.35 (95% confidence interval [CI], 1.54–7.29) in the left ear and 5.66 (95% CI, 2.01–15.98) in the right ear. CONCLUSIONS: This study suggested that the risk of hearing impairment in the DM group was significantly higher than that in the normal group in both ears, even when exposed to similar noise levels.
Audiometry, Pure-Tone
;
Blood Glucose
;
Cholesterol
;
Creatinine
;
Diabetes Mellitus
;
Ear
;
Fasting
;
Glucose
;
Hearing Loss
;
Hearing
;
Humans
;
Longitudinal Studies
;
Male
;
Noise
;
Proportional Hazards Models
;
Smoke
;
Smoking
;
Triglycerides
;
Ulsan
7.A Clinical Experience of Total Scalp Avulsion in a Male.
Jennifer Kim SONG ; Min Wook KIM ; So Min HWANG ; Kwang Ryeol LIM ; Yong Hui JUNG ; Sung Min AHN
Journal of the Korean Microsurgical Society 2011;20(1):74-77
Total scalp avulsion is rare but a devastating injury. This condition burdens the patient with disfigured cosmetic appearance and permanent psychosocial trauma. Throughout history, this condition has been favored in women working with mechanics since the long hair function as a vector appliance for oblique pull of the hair into a stationary torque. We present our experience of the replantation of the total avulsed scalp in male, first to be reported in Korea. Warm ischemic time was exceeding 16 hours along with severe crushed condition of the detached margin, a relatively satisfactory result was obtained.
Cosmetics
;
Female
;
Hair
;
Humans
;
Korea
;
Male
;
Mechanics
;
Replantation
;
Scalp
;
Torque
;
Warm Ischemia
8.Blood Lead Levels of Children in Ulsan Industrial Area.
Cheol In YOO ; Ji Ho LEE ; Choong Ryeol LEE ; Sung Ryul KIM ; Seon Ho LEE
Korean Journal of Preventive Medicine 1998;31(2):240-248
We conducted this study, to obtain basic data of lead concentrations in children of Ulsan industrial area and to evaluate the difference in blood lead levels between industrial area and suburban area. The study subjects were composed of 348 school children residing in industrial area and 100 school children of suburban area. There is no difference in age and sex distribution of study participants between industrial and suburban area. The obtained results were as follows: l. The geometric means of blood lead levels of study participants were 4.90 ng/dl, which is lower than current acceptable value 10 ng/dl. 2. The children residing in industrial area had the higher blood lead levels(5.26 ng/dl) than suburban children(3.81 ng/dl) with statistical significance(P<0.001).
Child*
;
Humans
;
Sex Distribution
;
Ulsan*
9.Multiple Epidermal Inclusion Cysts in Previous Bone Graft Site of the Thumb: A Case Report.
So Min HWANG ; Hong Il KIM ; Sung Min AHN ; Kwang Ryeol LIM ; Yong Hui JUNG ; Jennifer K SONG
Journal of the Korean Society for Surgery of the Hand 2011;16(4):247-250
We report a 71-year-old male presenting with painful growing mass on his left thumb. The patient had received iliac bone graft on his left thumb 20 years ago, and removed all the grafted bone 8 years ago due to recurrent ulcer. Biopsy revealed multiple eidermal inclusion cysts on the dorsal surface of the bone graft site. Surgeon should be aware of epidermal inclusion cyst occurred at the previous bone graft site of the finger.
Aged
;
Biopsy
;
Fingers
;
Humans
;
Male
;
Thumb
;
Transplants
;
Ulcer
10.Clinical outcomes of three- or five-day treatment with clomiphene citrate combined with gonadotropins and a timed intercourse cycle in polycystic ovary syndrome patients.
Sung Ah BAE ; Jong Kil JOO ; Jong Ryeol CHOI ; Sun Suk KIM ; Kyu Sup LEE
Clinical and Experimental Reproductive Medicine 2015;42(3):106-110
OBJECTIVE: This study aimed to investigate the effect of a new clomiphene citrate (CC) regimen on preventing thin endometrial lining in polycystic ovary syndrome (PCOS) patients receiving CC plus gonadotropin treatment with a timed intercourse cycle. METHODS: A total of 114 women with PCOS were included in this trial. Patients were divided into two groups and treated in accordance with the controlled ovarian stimulation (COS) protocol. In group A, 104 COS cycles in 67 patients were included, and in each cycle 150 mg CC was given for three days, starting from day 3. In group B, 69 COS cycles in 47 patients were included, in which 100 mg CC was given for five days, starting from day 3. The thickness of the endometrium was measured on the day of human chorionic gonadotropin (hCG) injection. Timed intercourse was recommended at 24 and 48 hours after the hCG injection. RESULTS: Additional doses of human menopausal gonadotropin and the number of days of hCG administration were not significantly different between the two groups. Endometrial thickness on the day of hCG administration was significantly larger in group A than group B (9.4+/-2.1 mm vs. 8.5+/-1.7 mm, p=0.004). The pregnancy rate was significantly higher in group A than in group B (38.4% vs. 21.7%, p=0.030). CONCLUSION: Three-day CC treatment resulted in a significantly higher pregnancy rate than the standard five-day CC treatment in a timed intercourse cycle in PCOS patients. Facilitating adequate endometrial growth via the early discontinuation of CC might be a crucial factor in achieving a higher pregnancy rate.
Chorionic Gonadotropin
;
Clomiphene*
;
Endometrium
;
Female
;
Gonadotropins*
;
Humans
;
Ovulation Induction
;
Polycystic Ovary Syndrome*
;
Pregnancy
;
Pregnancy Rate