No abstract available.
Allografts* ; Cartilage*

No abstract available.
Biofeedback, Psychology* ; Electric Stimulation* ; Pelvic Floor* ; Urinary Incontinence*

No abstract available.
Factor VIII* ; Hemophilia A* ; Humans

Transitional cell carcinoma of the urinary bladder is the most common cancer of the urinary tract and is characterized by frequent recurrence. Like the other malignant tumor, the genetic alterations leading to neoplastic transformation of the urothelium are related with the activation of oncogenes and loss of functional tumor suppressor genes. Cyclin D1 is a putative protooncogene as cell cycle regulator essential for G1 phase progression and is frequently overexpressed in several human tumor. In this study we performed immunohistochemical stainings of cyclin D1 and p53 in both primary and recurrent transitional cell carcinomas of urinary bladder from 56 patients including 20 cases of recurrent tumor, and compared their results with histopathologic features. The results were as follows. Cyclin D1 immunoreactivity was found in 10 of 10 cases (100%) of grade 1, 25 of 41 (61%) cases of grade 2, and 11 of 25 (44%) cases of grade 3 transitional cell carcinomas. p53 immunoreactivity was found in 40% of grade 1, 63% of grade 2, and 87% of grade 3 lesions. Cyclin D1 expression was significantly higher in Ta and T1 lesions than T2 to T4 by pathologic tumor stage. Conversely p53 immunoreactivity was increased in proportion to the T classification. Cyclin D1 was de creased in recurrent transitional cell carcinomas, compared with primary transitional cell carcinomas. However, there was no statistical significance. In conclusion, cyclin D1 immunoreactivity is associated with low histologic grade and low tumor stage. And there is inverse relationship between the cyclin D1 and p53 overexpression.
Carcinoma, Transitional Cell* ; Cell Cycle ; Classification ; Cyclin D1* ; Cyclins* ; G1 Phase ; Genes, Tumor Suppressor ; Humans ; Oncogenes ; Recurrence ; Urinary Bladder* ; Urologic Neoplasms ; Urothelium

No abstract available.
Adenocarcinoma*

To evaluate the effects of pregnancy-induced hypertension (PIH) to the iron status of fetuses, umbilical cord blood of 35 newborn borne by PIH mothers and of 37 normal term infants delivered at Yeungnam University Hospital from September 1, 1993 to September 30, 1994, were studied. The serum hemoglobin concentration of women with PIH was significantly higher than normal full-term pregnant women. There was no significant difference in serum hemoglobin concetration between women with PIH and normal full-term pregnant women and their newborn infants. There was no significant difference in serum hemoglobin concentration between infants iof women with PIH and normal full-term infants. The serum iron concentration of newborn infants of women with PIH was higher and the serum ferritin concentration of newborn infants of women with PIH was lower than normal full-term infants, but there were no significant difference between the two groups. The serum total iron-binding capactity and unsaturated iron-binding capacity of infants of women with PIH were significantly higher than normal full-term infants. The newborn infants of PIH women seemed that they might have occult depletion of iron store and need meticulous follow up during early neonatal period.
Female ; Ferritins ; Fetal Blood ; Fetus ; Follow-Up Studies ; Humans ; Hypertension* ; Hypertension, Pregnancy-Induced ; Infant ; Infant, Newborn* ; Iron ; Mothers* ; Pregnancy ; Pregnant Women

No abstract available.
Down Syndrome* ; Leukemia, Megakaryoblastic, Acute*

A 4-year-old boy has had a solitary sclerotic depressed plaque on the right anterior chest since birth. The histopathologic findings are consistent with morphea profunda: thickening, hyalinization, and homogenization of collagen bundles in the dermis and subcutaneous tissues, admixture with a prominent lymphocytic and plasma cell infiltrate, and sweat glands en-trapped between the thickened collagen bundles. We report a case of congenital solitary morphea profunda.
Child, Preschool ; Collagen ; Dermis ; Humans ; Hyalin ; Male ; Parturition ; Plasma Cells ; Scleroderma, Localized* ; Subcutaneous Tissue ; Sweat Glands ; Thorax

Nd-YAG laser is known as a safe and effective treatment for posterior capsular opacity after cataract surgery. We studied the ocular complications after Nd-YAG laser treatment in uveitis patients. From January 1991 to December 1996, we retrospectively investigated the complications of uveitis in 22 persons(25 eyes) after Nd-YAG laser posterior capsulotomy, and also investigated that of nonuveitis in 563 persons(635 eyes) as a control group. The uveitis cases consisted of six anterior uveitis, eight intermediate uveitis, seven Behcet`s syndromes, three panuveitis, and one posterior uveitis. In the uveitis group, the complications(18 eyes) consisted of three retinal detachments, one giant retinal tear, three glaucoma, two aggravations of uveitis, two vitreous opacities, one retinal emorrhage, one proliferative vitreoretinopathy, one hyphema, and four transient high intraocular pressures(IOP), and in the control group, it consisted of two subluxations of intraocular lens(IOL), three glaucomas, one retinal tear, three transient high IOPs, two vitreous opacities, two retinal hemorrhages, three macular holes, two retinal detachments, and five cystoid macular edemas. From our experience, the incidence of complications after Nd-YAG laser posterior capsulotomy in uveitis was higher than that in nonuveitis. It was also noted that it is necessary to follow up thoroughly the complications after Nd-YAG laser posterior capsulotomy in uveitis patients.
Cataract ; Follow-Up Studies ; Glaucoma ; Humans ; Hyphema ; Incidence ; Lasers, Solid-State* ; Macular Edema ; Panuveitis ; Posterior Capsulotomy* ; Retinal Detachment ; Retinal Hemorrhage ; Retinal Perforations ; Retinaldehyde ; Retrospective Studies ; Uveitis* ; Uveitis, Anterior ; Uveitis, Intermediate ; Uveitis, Posterior ; Vitreoretinopathy, Proliferative

The herniation of intervertebral disc is possibly diagnosed through the myelography, electromyography, discography or computerized tomography. Among them, the myelography is regarded as the popularized method that helps accurate analysis on the location and pattern of the lesion. The authors have studied 363 cases of herniated intervertebral disc with respect to the diagnostic accuracy of myelographic examination from January, 1982 to December, 1985 at the Department of Orthopedic Surgery and Radiology, National Police Hospital. The results were as follows; 1. The most common age group was 21 to 30 years old and ratio of male and female was 9.7: l. 2. The most common site of the lesion was between L4 and L5 vertebra in myelography. 3. Of the 363 cases which underwent the myelography, 305(84.0%) represented positive findings. 4. Myelographic accuracy was coincided with the clinical diagnosis regarding the location of herniation of intervertebebral disc in 262 cases(72.1%).
Diagnosis ; Electromyography ; Female ; Humans ; Intervertebral Disc ; Male ; Methods ; Myelography ; Orthopedics ; Police ; Spine