1.An Isolated Dislocation of Tarsal Navicular Bone: a Case Report
Seung Yul CHOI ; Jang Sung LEE ; Byung Guk KIM ; Min Sung KIM
The Journal of the Korean Orthopaedic Association 1989;24(4):1264-1266
Dislocation involving tarsal navicular is a extremely rare injury compare to dislocation of other tarsal bone. One case of the tarsal navicular dislocation associated with subluxation of the midtarsal joint treated by open reduction and arthrodesis was reported.
Arthrodesis
;
Dislocations
;
Joints
;
Tarsal Bones
2.The Treatment of Scaphoid Nonunion
Kwon Ick HA ; Sung Ho HAHN ; Min Young JUNG ; Mun Sung KIM ; Hee Sun JANG
The Journal of the Korean Orthopaedic Association 1985;20(6):1073-1079
Fracture of the scaphoid constitute 60% to 70% of all diagnosed carpal injury. The acute fracture will heal approximately 90% of the time if recognized early and properly immobilized. But nonunion are common since the symtoms do not alert patients to seek early medical treatment and the diagnosis is easily missed. Authors have experienced 19 cases of scaphoid nonunion and accomplished good result in all case by Russe procedure. The results were summerized as follow: 1 The cause of fratures was mainly due to fall down dinjury (36.8%). 2. The most common mechanism of the fracture was fall on the outstretched hand (52.7%). 3. Fractures were shown on the anterior-posterior, lateral and billiards view in all cases. 4. In ten cases, the fractures were found on the waist of scaphoid. 5. The cases of nonunion were probably inadequate intial treatment and delayed diagnosis. 6. The good results were obtained by bone graft according to Russe procedure.
Delayed Diagnosis
;
Diagnosis
;
Hand
;
Humans
;
Transplants
3.Cyto - molecular Biologic Characterization of c - myc , erb B and EGF - Receptor in Squamous Cell Carcinoma.
Kyu Suk LEE ; Yoon Yae CHOI ; Joon Young SONG ; In Jang CHOI ; Sung Ik JANG ; Won Ki BAEK ; Min Ho SUH
Korean Journal of Dermatology 1994;32(2):223-233
BACKGROUND: Oncogenes and EGF-Receptor(EGFR) may be involved n different stages of the multistep carcinogenesis process. A specific pattern of karyotypic abnormalities in solid tumors can be detected by cytogenetic methods. OBJECTIVE: This study is intnded to observe the cytomolecular kiologic chracterization of c-myc, erb B and EGFR genes in squasnous cell carcinoma(SCC) of the skin and cervix. METHODS: We have eytogenet,ically examined the short-term culturs from SCC. The rearrangement, amplification or expressi.on of erb B, c-myc, and EGFR genes were studied by Southern blot, analysis of genomic DNA and by slot blot analysis of tota! RNA extracted from biopsies of normal skin and SCC tissues. EGFR expression was examined immunohistochemially using monoclonal antibodies and the localizat,ion of the c-myc oncogene mRNA by in situ hybridization. RESULTS: A remarkably structural aberration was del 6(q21-qter) counted 20 metaphases among 28 metaphases ana1yzed. In nunierical aberration, all chromosomes were lost or gained randomly. Amenploid including triploid and tetraploid were observed in 8 metaphases, 6 tumor cells contained marker chromosome. In Southern blot analysis, rearrangement and amglificaton of EGFR in primary squamous cell carcinoma of cervix uteri and skin respectively. In slot blot analysis, the levels of c-myc, erb B and EGFR mRNA increaaed respectively 3.5, 2.5 and 2.8 times in SCC when compared to normal tissues. In immunoperoxidase stain, EGFR was present, in SCC where keratinocytes with strong cyto-plasmic staining but no membr, line labelling, where as in normal skin the were primarily present in t,he membrane and cytoplasm of basal cells. In situ hybridization with c-myc cDNAs allowed detection of grains representative of biotin labelled cDNA-mRNA hybrids in the frozden section of SCC tissues. CONCLUSION: These results suggest that specific patterns of karyotypir abnormalites, rearrangement, or amplification of EGFR gene, and overexpression of oncogenes and EGFR gene may be associated with the carcinogenesis of SCC.
Antibodies, Monoclonal
;
Biopsy
;
Biotin
;
Blotting, Southern
;
Carcinogenesis
;
Carcinoma, Squamous Cell*
;
Edible Grain
;
Cervix Uteri
;
Cytogenetics
;
Cytoplasm
;
DNA
;
DNA, Complementary
;
Epidermal Growth Factor*
;
Female
;
Genes, erbB-1
;
In Situ Hybridization
;
Keratinocytes
;
Membranes
;
Metaphase
;
Oncogenes
;
RNA
;
RNA, Messenger
;
Skin
;
Tetraploidy
;
Triploidy
4.Weekend Admission and Mortality in Patients With Traumatic Brain Injury:A Meta-analysis
Kyoung Min JANG ; Ju Sung JANG
Korean Journal of Neurotrauma 2023;19(4):422-433
Objective:
Previous studies have reported the presence of a “weekend effect” with respect to mortality in serious emergency admissions, including cases of traumatic brain injury (TBI).However, the relationship between weekend hospitalization and TBI mortality has not been fully established. This study aimed to conduct a systematic review of available evidence and investigate differences in mortality among TBI patients between weekday and weekend admissions.
Methods:
Electronic databases including PubMed, Cochrane Library, and Embase were used to obtain relevant articles. Mortality, as the primary outcome of interest, encompassed inhospital or 30-day mortality. Mortality rates were compared between the 2 groups, weekend and weekday admissions. Additionally, meta-regression analysis was performed on potential confounders to verify and provide comparative results.
Results:
A total of 7 studies involving 522,942 TBI patients were eligible for inclusion in the synthesis of the systematic review. Of these patients, 71.6% were admitted during weekdays, whereas 28.4% were hospitalized on weekends. The overall integrated mortality was 11.0% (57,286/522,942), with a mortality rate of 10.8% in the weekday group and 11.3% in the weekend group. Pooled analysis revealed no significant difference in mortality between the weekday and weekend groups (risk ratio, 0.99; 95% confidence interval, 0.90–1.09; p=0.78).Furthermore, the meta-regression analysis for sensitivity assessment showed no modifying effect on mortality (p=0.79).
Conclusion
This study found no difference in mortality rates between weekday and weekend admissions among TBI patients. Additional sensitivity analyses also demonstrated no significant increase in the risk of mortality in the weekend group.
5.A Case of Hypopigmented Mycosis Fungoides.
Min Soo JANG ; Joon Sung YANG ; Young Soo CHAE ; Kee Suck SUH ; Sang Tae KIM
Korean Journal of Dermatology 1997;35(1):196-199
No abstract available
Mycosis Fungoides*
6.(99m)Tc-HDP Bone Scan Findings of Acute Rhabdomyolysis of Lumbar Multifidus and Thigh Muscles and Bone Scan and US Signs of Acute Tubular Necrosis in Excessive Rabbit's Leaping: A Case Report.
Nuclear Medicine and Molecular Imaging 2008;42(3):249-252
No abstract available.
Muscles
;
Necrosis
;
Rhabdomyolysis
;
Thigh
7.Relationship between Pachymeningeal Enhancement on Brain MRI and CSF leakage on Radioisotope Cisternography in Patients with Orthostatic Headache.
Journal of the Korean Neurological Association 2000;18(1):38-43
BACKGROUND: In orthostatic headache (OH) associated with low cerebrospinal fluid (CSF) pressure, loss of CSF vol-ume reflected by pachymeningeal enhancement (PCE) on brain magnetic resonance image (MRI) has been suggested as a pathogenenesis according to Monro-Kellie rule. We attempted to test the following hypotheses; 1) OH is caused by loss of CSF volume, 2) CSF volume loss in OH is caused by hyperabsorption of CSF or 3) by decreased production of CSF. METHODS: Nineteen patients with OH were recruited. Lumbar puncture, brain MRI and radioisotope cisternogra-phy (RIC) were performed in all of them. We evaluated duration of headache from onset to first evaluation, presence of PCE on MRI and CSF leakage (CSFL) on RIC. Firstly, we compared duration of headache between patients with and without PCE. Secondly, between those with and without PCE, we analyzed presence of CSF fistula and demonstration of CSFL on RIC. RESULTS: Mean duration (16.1 +/-19.6) of headache in 13 patients with PCE (66.7%) was significantly longer than in those without PCE (P=0.036). Among 19 patients, CSF fistula was detected in 13 patients (72%) and CSFL in 16 patients (88.9%). There was no significant difference in CSF fistula presence (P=0.114) and in demonstra-tion of CSFL between those with and without PCE. In 16 patients, delayed appearance of radioisotope along cerebral interhemispheric and sylvian regions was shown on RIC. CONCLUSIONS: Pain in OH may be caused by CSF volume loss, however, whether CSF volume loss is caused by CSF hyperabsorption or decreased production remains to be clarified.
Brain*
;
Cerebrospinal Fluid
;
Fistula
;
Headache*
;
Humans
;
Magnetic Resonance Imaging*
;
Spinal Puncture
8.Tragus formation by chondrocutaneous flap in reconstruction of microtia.
Jang Deog KWON ; Jin O KIM ; Rong Min BAEK ; Kap Sung OH
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1998;25(6):1033-1038
Tanzer reported microtia reconstruction using autogenous costal cartilage, thereafter so many plastic surgeons have tried various modification to get further refinement of reconstructed auricle. But the multiple stages of ear reconstruction required prolonged hospitalization and cost. In order to decrease the number of surgical stages and for the maximal convolution, we have employed a surgical procedure with three layered costal cartilage graft for the high profile auricle, concha formation and lobule transposition at the same time. However, it has still been difficult to reconstruct the tragus in cases of microtia that lack such component. We reconstructed the tragus using part of the microtic ear in addition to our above procedure simultaneously. This procedure is started with transposition of the lower two-thirds of the microtic ear to make lobule and then the upper third of the microtic ear is elevated as a chondrocutanenous flap which is then transposed 120-180degree C downwards to reposition at the area anterior to the conchal cavity. Using this technique, we have reconstructed 28 microtic ears. Adequate positioning of the auricle and tragus have been achieved and a more natural auricle obtained.
Cartilage
;
Ear
;
Hospitalization
;
Transplants
9.Clinical Significance of Ureterosigmoidostomy in Urinary Diversion.
Korean Journal of Urology 1985;26(5):481-487
Many urologists began to abandon ureterosigmoidostomy as the preferred method of diversion nearly 35 years ago when Bricker described the ileal conduit. The complications were instrumental in dissuading many urologist. A clinical observation on 14 cases of ureterosigmoidostomy was made on who had been admitted to the Department of urology from January, 1976 to march, 1985. Use of the combined procedure seems to minimize the incidence of pyelonephritis, and the incidence of hypercchloremic acidosis as a long-term complication appears to be an acceptable problem. Ureterosigmoidostomy should be considered more frequently as the method of urinary diversion.
Acidosis
;
Incidence
;
Pyelonephritis
;
Urinary Diversion*
;
Urology
10.Clinical and histopathological studies on ovarian tumors.
Yeun Jin KIM ; Min Jung LEE ; Un Ik JANG ; Jung Su GOO ; Sung Hee JUNG
Korean Journal of Obstetrics and Gynecology 1993;36(7):2220-2230
No abstract available.