1.Use of Quantitative CT to Predict Postoperative Lung Function (Comparison of Quantitative CT and Perfusion Lung Scan).
Jo Han RHEE ; Seog Jae LEE ; Sung Jin KIM
The Korean Journal of Thoracic and Cardiovascular Surgery 2000;33(10):798-805
BACKGROUND: the prediction on changes in the lung function after lung surgery would be an important indicator in terms of the operability and postoperative complications. In order to predict the postoperative FEV1 - the commonly used method for measuring changes in lung function- a comparison between the quantitative CT and the perfusion lung scan was made and proved its usefulness. MATERIAL AND METHOD: The subjects included 22 patients who received perfusion lung scan and quantitative CT preoperatively and with whom the follow-up of PFT were possibles out of the pool of patients who underwent right lobectomy or right pneumonectomy between June of 1997 and December of 1999. The FEV1 and FVC were calibrated by performing the PFT on each patient and then the predicted FEV1 and FVC were calculated after performing perfusion lung scan and quantitative CT postoperatively. The FEV1 and FVC were calibrated by performing the PFT after 1 week and after 3 momths following the surgery. RESULTS: There was a significant mutual scan and the actual postoperative FEV1 and FVC at 1 week and 3 months. The predicted FEV1 and FVC(pneumonectomy group : r=0.962 and r=0.938 lobectomy group ; r=0.921 and r=913) using quantitative CT at 1 week postoperatively showed a higher mutual relationship than that predicted by perfusion lung scan(pneumonectomy group : r=0.927 and r=0.890 lobectomy group : r=0.910 and r=0.905) The result was likewise at 3 months postoperatively(CT -pneumonectomy group : r=0.799 and r=0.882 lobectomy group : r=0.934 and r=0.932) CONCLUSION: In comparison to perfusion lung scan quantitative CT is more accurate in predicting lung function postoperatively and is cost-effective as well. Therefore it can be concluded that the quantitative CT is an effective method of replacing the perfusion lung scan in predicting lung function post-operatively. However it is noted that further comparative analysis using more data and follow-up studies of the patients is required.
Follow-Up Studies
;
Humans
;
Lung*
;
Perfusion*
;
Pneumonectomy
;
Postoperative Complications
2.Right Thalamic Hemorrhage Resulting from Low-voltage Electrical Injury: A Case Report.
Journal of the Korean Society of Emergency Medicine 2012;23(4):555-558
We report on a case of right thalamic hemorrhage resulting from low-voltage electrical injury caused by contact between a wet hand and an electronic scale. The patient was treated with clopidogrel for control of a previous cerebral infarction. The patient complained of numbness of the left upper extremity. On neurological examination, decreased motor power of her left side, grade IV, was observed. Findings on computerized tomography of the brain revealed a right thalamic hemorrhage. To the best of our knowledge, cerebral hemorrhage resulting from low-voltage electrical injury has not been previously reported in the literature.
Brain
;
Cerebral Hemorrhage
;
Cerebral Infarction
;
Electric Injuries
;
Electronics
;
Electrons
;
Hand
;
Hemorrhage
;
Humans
;
Hypesthesia
;
Neurologic Examination
;
Ticlopidine
;
Upper Extremity
3.Bilateral Coronary Artery-Right Ventricular Fistula in Newborn: Associated with Atrial Septal Defect.
Jo Won JUNG ; Jong Kyun LEE ; Jun Hee SUL ; Sung Kyu LEE ; Dong Gwan HAN
Korean Circulation Journal 1991;21(6):1259-1264
Bilateral coronary artery fistula is very uncommon congenital anomaly which occupy small percentage of all congenital coronary artery fistula. About 20% of the cases associated with additional congenital heart disease. And it may cause congestive heart failure, especially severely in neonate. We experienced a case of neonate who was 1 day-old-male with bilateral coronary artery-right ventricular fistula associated with atrial septal defect and congestive heart failure. The Patient was admitted because dyspnea, cyanosis since birth. 2D ecgicardiogram and cardiac catheterization revealed that a fistulous communicating ; forming a large aneurysm, was noted from bilateral coronary artery emptied into the right ventricle, and there was oxygen step-up in right ventricle.
Aneurysm
;
Cardiac Catheterization
;
Cardiac Catheters
;
Coronary Vessels
;
Cyanosis
;
Dyspnea
;
Fistula*
;
Heart Defects, Congenital
;
Heart Failure
;
Heart Septal Defects, Atrial*
;
Heart Ventricles
;
Humans
;
Infant, Newborn*
;
Oxygen
;
Parturition
4.Spontaneous left external iliac vein rupture.
Ick Hee KIM ; Gyu Rak CHON ; Yoon Sik JO ; Sung Bae PARK ; Sang Don HAN
Journal of the Korean Surgical Society 2011;81(Suppl 1):S82-S84
We report a 72-year-old female patient with spontaneous rupture of the left external iliac vein. She visited our hospital for abdominal and back pain. She had the abnormal finding of hemoperitoneum. We performed an emergency operation with diagnosis of left ovarian cyst rupture though she suffered from spontaneous rupture of the left external iliac vein. This case provides insight to the experience of spontaneous rupture of the left external iliac vein.
Aged
;
Back Pain
;
Emergencies
;
Female
;
Hemoperitoneum
;
Humans
;
Iliac Vein
;
Ovarian Cysts
;
Rupture
;
Rupture, Spontaneous
5.The Prediction of Preterm Labor : The Role of Corticotropin-Releasing Hormone in Amniotic Fluid.
Hye Gyung GWON ; Young Han KIM ; Chang Hee LEE ; Jae Sung JO ; Yong Won PARK
Korean Journal of Obstetrics and Gynecology 2000;43(12):2146-2151
No abstract available.
Amniotic Fluid*
;
Corticotropin-Releasing Hormone*
;
Female
;
Obstetric Labor, Premature*
;
Pregnancy
6.The clinical study of the temporal bone fractures.
Yong Ki KIM ; Sung Chan KIM ; Hyung Ook PARK ; Han Jo NA ; Bong Nam CHOI
Korean Journal of Otolaryngology - Head and Neck Surgery 1992;35(1):67-74
No abstract available.
Temporal Bone*
7.A Comparative Analysis of Cervical Pap Smears Prepared by Conventional and ThinPrep Method.
Yeon Hwa LA ; Gyung Chul JO ; Sung Tae HAN ; Suk Hee JUNG ; Jung Rae SEO ; Woo Chul JUNG ; Sung Won LEE ; Yong JO ; Eui Sun RO
Korean Journal of Obstetrics and Gynecology 2000;43(8):1450-1458
No abstract available.
8.Clinical Outcomes of Double-dose Aflibercept Treatment for Refractory Wet Age-related Macular Degeneration
Sung Hyun JO ; Han Jo KWON ; Sung Who PARK ; Ik Soo BYON
Journal of the Korean Ophthalmological Society 2024;65(8):500-507
Purpose:
To evaluate the clinical outcomes and prognostic factors of double-dose aflibercept in patients with refractory neovascular age-related macular degeneration (nAMD).
Methods:
We reviewed the medical records of nAMD patients treated with a double dose of aflibercept (4 mg/0.1 mL) due to an inadequate response to standard 8-weekly intravitreal injections of 2 mg/0.05 mL aflibercept. The assessment at week 8 after treatment included changes in subretinal/intraretinal fluid (SRF/IRF) and best-corrected visual acuity, with patients showing absence or reduction in SRF/IRF classified as the response group. Baseline factors influencing clinical outcomes were analyzed, including central macular thickness (CMT), central choroidal thickness (CCT), size of choroidal neovascularization (CNV), CNV subtype, and maximum height of SRF and IRF.
Results:
The study included 95 eyes of 95 subjects, with 61 eyes (64.2%) categorized as the response group following double-dose treatment. Responders exhibited thicker CCT (290.4 μm vs. 194.0 μm, p < 0.001), thinner CMT (251.2 μm vs 311.1 μm, p = 0.018), smaller CNV area (2.718 mm2 vs. 3.964 mm2, p = 0.034), and a higher prevalence of type 1 CNV (85.2% vs. 58.8%, p = 0.011) compared to the non-response group. Multivariate binary logistic regression analysis identified thicker CCT (p < 0.001, r = 1.016), thinner CMT (p = 0.014, r = 0.988), smaller CNV area (p = 0.015, r = 0.662), and type 1 CNV (p = 0.001, r = 0.061) as factors associated with better anatomical outcomes.
Conclusions
Double-dose aflibercept was effective in 64% of patients with refractory nAMD, suggesting it may be considered for those with small CNV areas, thinner CMT, and thicker CCT.
9.Impact of Titer of Toxoplasma Immunoglobulin G on the Diagnosis of Ocular Toxoplasmosis
Sung Hyun JO ; Bo Hyun PARK ; Han Jo KWON ; Ik Soo BYON ; Jong Youn YI ; Sung Who PARK
Journal of the Korean Ophthalmological Society 2024;65(5):320-327
Purpose:
To assess the impact of toxoplasma immunoglobulin G (IgG) titers on the diagnosis of active ocular toxoplasmosis.
Methods:
We retrospectively analyzed the medical records of patients tested for toxoplasma IgG at our uveitis clinic. Active ocular toxoplasmosis was clinically diagnosed based on wide-angle fundus photography and disease progression. Patients with IgG titers ≥ 30 IU/mL were classified as seropositive-high titer, those with IgG titers of 1.6-30 IU/mL as seropositive-low titer, and the remaining patients as seronegative. We compared the proportion of active ocular toxoplasmosis among these groups. Additionally, we evaluated the sensitivity and specificity of each titer and attempted to determine an ideal reference titer for toxoplasma IgG in diagnosing active ocular toxoplasmosis.
Results:
Out of 824 patients, 86 (10.4%), 88 (10.7%), and 650 (78.9%) were categorized as seropositive-high titer, seropositivelow titer, and seronegative, respectively. Among these patients, 34 in the seropositive-high titer group and 2 in the seropositive- low titer group were clinically diagnosed with active ocular toxoplasmosis. The false-positive rate was significantly different between the groups, being 60.5% in the seropositive-high titer group and 97.7% in the seropositive-low titer group (p < 0.001). The receiver operating characteristic curve indicated that 37.70 IU/mL could be an ideal reference titer for diagnosing ocular toxoplasmosis.
Conclusions
The false-positive rate was notably lower (60.5%) in patients with IgG titers ≥ 30 IU/mL compared to those with titers of 1.6-30 IU/mL (97.7%). Therefore, not only the presence of IgG but also the level of titer appears to be important in diagnosing ocular toxoplasmosis.
10.Clinical Outcomes of Double-dose Aflibercept Treatment for Refractory Wet Age-related Macular Degeneration
Sung Hyun JO ; Han Jo KWON ; Sung Who PARK ; Ik Soo BYON
Journal of the Korean Ophthalmological Society 2024;65(8):500-507
Purpose:
To evaluate the clinical outcomes and prognostic factors of double-dose aflibercept in patients with refractory neovascular age-related macular degeneration (nAMD).
Methods:
We reviewed the medical records of nAMD patients treated with a double dose of aflibercept (4 mg/0.1 mL) due to an inadequate response to standard 8-weekly intravitreal injections of 2 mg/0.05 mL aflibercept. The assessment at week 8 after treatment included changes in subretinal/intraretinal fluid (SRF/IRF) and best-corrected visual acuity, with patients showing absence or reduction in SRF/IRF classified as the response group. Baseline factors influencing clinical outcomes were analyzed, including central macular thickness (CMT), central choroidal thickness (CCT), size of choroidal neovascularization (CNV), CNV subtype, and maximum height of SRF and IRF.
Results:
The study included 95 eyes of 95 subjects, with 61 eyes (64.2%) categorized as the response group following double-dose treatment. Responders exhibited thicker CCT (290.4 μm vs. 194.0 μm, p < 0.001), thinner CMT (251.2 μm vs 311.1 μm, p = 0.018), smaller CNV area (2.718 mm2 vs. 3.964 mm2, p = 0.034), and a higher prevalence of type 1 CNV (85.2% vs. 58.8%, p = 0.011) compared to the non-response group. Multivariate binary logistic regression analysis identified thicker CCT (p < 0.001, r = 1.016), thinner CMT (p = 0.014, r = 0.988), smaller CNV area (p = 0.015, r = 0.662), and type 1 CNV (p = 0.001, r = 0.061) as factors associated with better anatomical outcomes.
Conclusions
Double-dose aflibercept was effective in 64% of patients with refractory nAMD, suggesting it may be considered for those with small CNV areas, thinner CMT, and thicker CCT.