We report a 55-year-old male, who has had erythematous, scaly, verrucous plaque on the left lower leg. About 1 year ago, rice sized erythematous papule on the left lower leg was developed. The lesion had been aggravated abruptly and rapidly in size since about one month ago. Histopathologic finding showed clusters of fungal spores in the upper dermis and intraepidermal microabscesses. The patient had been treated with wide excision and intravenous injection of amphotericin B. We observed a good response without evidence of recurrence.
Amphotericin B ; Chromoblastomycosis ; Dermis ; Humans ; Injections, Intravenous ; Leg ; Male ; Middle Aged ; Recurrence ; Spores, Fungal

A 45 year-old Korean woman presented with multiple pruritic umbilicated papules on both ankles of 3 months duration. Histopathologic findings showed calcium deposits in the upper dermis and the transepidermal elimination of calcium. This is a very rare presentation of calcinosis cutis.
Ankle ; Calcinosis* ; Calcium ; Dermis ; Female ; Humans

A 37-year-old man was diagnosed as having chronic renal failure received hemodialysis, Five months after starting hemodialysis developed rice to pea sized erythematous follicular papvles on the posterior neck and trunk which was accompanied by mild pruritus. Histopathologically the lesion showed typical finding of perforating folliculitis and Pickers nodule like changes in the adjacent epidermis.
Adult ; Epidermis ; Folliculitis* ; Humans ; Kidney Failure, Chronic ; Neck ; Peas ; Pruritus ; Renal Dialysis*

No abstract available.
Carcinoma, Squamous Cell* ; Epidermolysis Bullosa*

We herein report a case of palmar fibromatosis, who was 78-year-old male and had had multiple variable-sized subcutaneous hard nodules on the left palm for 2 months. Histopathologic findings of the lesion revealed that the nodules were highly cellular, containing numerous spindle shaped cells. Ultrastructurally, intracytoplasmic micrcfilaments were present, and the nuclei were extremely indented by one or more transverse folds. These findings suggested the cells were myofibroblasts.
Aged ; Fibroma* ; Humans ; Male ; Myofibroblasts

A 50-year-old man developed 3cm sized, well-marginated, subcutaneous mass on the right upper back. Histopathologic finding showed the lipomatous tissue was replaced by a mixture of uniform spindle cells and mature fat cells that were closely associated with a mucoid matrix and a varying number of collagen fibers. The patient had been treated with excision and showed no evidence of recurrence.
Adipocytes ; Collagen ; Humans ; Lipoma* ; Middle Aged ; Recurrence

Occult syringoma means a clinically inapparent tumor of the swea gland that are histologically similar but not identical with the common syringoma. They may occur in a variety of inflammatory skin lesions and cutaneous neoplaams as a reactive process. We report herein a case of diffuse alopecia areata associated with occult syringoma in the scalp of a 57-year-old man. Our patient developed progressive, fairly well circ amscribed patches of alopecia and diffuse hair loss over a 1 month period. Histopathological examinaiion revealed non-scaring alopecia and a proliferation of eccrine ductal structures in the upper dermis. These ductal structures resembled syringoma. Only minimal focal fibrosis was occasionally observed arcund the hair follicles. We believe that occult syringona is a reactive process and is secondary to active inflarnmation or dermal fibrosis. It has been most commonly observed in scarring alobiecias but plays no significant role in the etiology of hair loss.
Alopecia Areata ; Alopecia* ; Cicatrix ; Dermis ; Fibrosis ; Hair ; Hair Follicle ; Humans ; Middle Aged ; Scalp ; Skin ; Syringoma*

A 52-year-old man with multiple myeloma developed cutaneous nodules while being treated with melphalan and prednisolone. A biopsy specimen showed dermal infiltration by well differentiated plasma cells similar to those found on bone marrow biopsy. The use of peroxidase anti-peroxidase to demonstrate the monoclonality or polyclonality of the cytomplasmic immunoglohulins in the tumor cells revealed a positivity for IgG and 1 chain (ie, monotypic staining). Ultrastructurally, each plasmacytoma cell contained varyting amounts of rough endoplasmic reticulum and Golgi-apparatus. The cutnneous nodules completely disappeared after radiotherapy
Biopsy ; Bone Marrow ; Endoplasmic Reticulum, Rough ; Humans ; Immunoglobulin G ; Melphalan ; Middle Aged ; Multiple Myeloma* ; Peroxidase ; Plasma Cells ; Plasmacytoma* ; Prednisolone ; Radiotherapy

Phakomatosis pigmentovascularis is characterized by the coexistence of pigmentary nevus and hemangioma. Since the term was first described by Ota et al in 1947, about 80 cases have been reported in the literature. In 1979, Hasegawa et al subclsssified the disorder into eight types : type I, nevus flammeus and nevus pigmentosus et verrucosus, type II, nevus flamme is and dermal melanocytosis, type III nevus flammeus and nev.us spilus, type IV, nevus flammeus, dermal melanocytosis and nevus spilus. Each type is subdivided into localized(a) and systemic(b) types, A 25-year-old male had brown papules on the left knee and thigh and purple patches on the left leg that had been present for approximately 7 years. He had no concon ittant systemic disease. The histopathologic findings on brown papules and purple patches are compatible with epidermal nevus and nevus flammeus respectively. We herein report a case of phakomatosis pigmentovascularis type I a.
Adult ; Down Syndrome ; Hemangioma ; Humans ; Knee ; Leg ; Male ; Neurocutaneous Syndromes* ; Nevus ; Port-Wine Stain ; Thigh

No abstract available.
Epidermal Cyst* ; Nevus*