Sertoli-Leydig cell tumor is a rare sex-cord stromal tumor of the ovary and accounts for less than 0.5% of all ovarian tumors. It is among the most fascinating from pathologic and clinical viewpoints in masculinization. We experience an unusual case of a poorly differentiated Sertoli-Leydig cell tumor in 60-year-old woman who showed masculinization and present it with brief review of literature.
Female ; Humans ; Middle Aged ; Ovary* ; Sertoli-Leydig Cell Tumor*

To observe the effect of serious illness, surgical trauma, body weight, and clofibrate on serum lipids, the serum levels of cholesterol and triglyceride with lipoprotein patterns by electrophoresis on cellulose acetate membrane were studied in 30 normal persons, 18 patients with coronary heart disease, 26 patients with cerebral thrombosis, and 7 surgical patients. The results obtained were as follows; 1. The values of serum cholesterol and triglyceride in cerebral thrombosis and coronary heart disease were markedly higher than those of control, and the optic dinsities of each serum lipoprotein fractions were also increased significantly. 2. Serum lipoprotein type IIa and IIb were more frequently observed than type IV in cerebral thrombosis and coronary heart disease. 3. The change of serum cholesterol and triglyceride related moderately to relative body weight in normal persons. 4. The decrease in serum cholesterol occured on the 1st day following surgery, and recovered to 97.8% of the preoperation level on the 7th day. The serum triglyceride started to increase on the 3rd day following surgery, and reached to 115.1% of the preoperation level on the 7th day. 5. After attack of cerebrovascular accident the serum cholesterol and triglyceride level increased slowly to the 122.1% and 133.1% of the each lst day level on the 7th day. 6. The serum lipid lowering effect of clofibrate was most conspicuous in the hypertriglyceridemic patients, especially during lst and 2nd week after medication, and mixed hyperlipidemic patients responded moderately. But pure hypercholesterolemic patients resisted completely. The optic densities of each serum lipoprotein fraction were also decreased in drug responded groups.
Body Weight ; Cellulose ; Cholesterol ; Clofibrate ; Coronary Disease ; Electrophoresis ; Humans ; Intracranial Thrombosis ; Lipoproteins ; Membranes ; Stroke ; Triglycerides

The serum cholesterol and triglyceride levels were measured and the lipoprotein patterns by electrophoresis on cellulose acetate membrane were observed in 30 normal Koreans, 26 patients with cerebrovascular accident, and 18 patients with coronary heart disease. Similar measurements and observations were made in normal Koreas, surgical patients, the patients with cerebrovascular accident and hyperlipidemia in an attempt to examine the effects of body weight, surgical operations, cerebrovascular accident and the administration of clofibrate on serum lipids. The results obtained were as follows. 1. The mean values of serum cholesterol and triglyceride, which shows moderately significant correlation to the body weight in normal Koreans, were markedly higher in the patients with cerebrovascular accident and coronary heart disease than those of control. 2. Serum pre-beta- and beta-lipoprotein patterns in the densitometry of the serum lipoprotein electropherogram of the patients with coronary heart disease were larger than those of control, but the densitometric patterns of the patients with cerebrovascular accident were similar to those of control. Serum pre-beta- and beta-lipoprotein-cholesterol levels of the patients with cerebrovascular accident and coronary heart disease were higher than those of control. 3. Serum hyperlipoproteinemic type IIa and IIb were more frequently observed than type IV in the patients with cerebrovascular accident and coronary heart disease. 4. Serum cholesterol levels decreased to 74.9% of preoperation levels on the 1st postoperative day and recovered to 97.8% of preoperation levels on the 7th day. Serum triglyceride levels started to increase on the 3rd postoperative day, and reached to 115.3% of preoperation levels on the 7th day. After attack of cerebrovascular accident, serum cholesterol and triglyceride levels increased slowly to 121.7% and 133.7% of the each 1st day levels on the 7th day. 5. Serum lipid lowering effect of clofibrate was most conspicuous in the hypertriglyceridemic patients, especially during the 1st and 2nd weeks after initiation of medication, and moderately in the mixed hyperlipidemic patients. Serum pre-beta- and beta-lipoprotein-cholesterol levels were decreased after 8 weeks of clofibrate therapy, but alpha-lipoprotein-cholesterol levels did not change significantly.
Body Weight ; Cellulose ; Cholesterol* ; Clofibrate ; Coronary Disease ; Densitometry ; Electrophoresis ; Humans ; Hyperlipidemias ; Korea ; Lipoproteins* ; Membranes ; Stroke ; Triglycerides*

One hundred and seven cases of coronary heart disease were clinically studied at Seoul National University Hospital from September 1967 to August 1971 and following results were obtained. 1. The total cases were composed with 70 cases of myocardial infarction (46 cases of acute type and 24 cases of old type), 26 cases of angina pectoris and 11 cases of coronary insufficiency. 2. The ratio of male to female was 3.5:1, and over two-thirds of patients were sixth and seventh decade in ages. 3. As the underlying diseases, hypertension was found in 38.3% of the cases, and diabetes mellitus in 10.3%. 4. Among the various symptoms, precordial pain was a most common and characteristic, which was noted in 81.1% of the cases. Pain was radiated to the left arm and/or left shoulder in 45.2% of the cases. 5. In 57.2% of the cases, serum cholesterol was more than 200mg%. 6. The ratio between anterior and posterior wall infarction on electrocardiogram was about 3.5:1. 7. Left ventricular hypertrophy was the most frequently noted finding, and sinus tachycardia, low voltage, ventricular premature beat, myocardial ischemia, and others were also observed in some cases. 8. Mortality rate was 8.4%, and the major causes of death were cardiogenic shock and ventricular fibrillation.
Angina Pectoris ; Arm ; Cardiac Complexes, Premature ; Cause of Death ; Cholesterol ; Coronary Disease* ; Diabetes Mellitus ; Electrocardiography ; Female ; Humans ; Hypertension ; Hypertrophy, Left Ventricular ; Infarction ; Male ; Mortality ; Myocardial Infarction ; Myocardial Ischemia ; Seoul ; Shock, Cardiogenic ; Shoulder ; Tachycardia, Sinus ; Ventricular Fibrillation

There are many complications related to paralyzed patients. Heterotopic ossification in pressure sore patients is reported to be rarely developed, but once it occurs, it frequently causes joint stiffness which may aggrevate the pressure sore wound. This paper was based on a clinical study of heterotrophic ossification in 6 quadriplegic and paraplegic patients from 1988 to 1997 at St. Paul's Hospital. All were males aged between 22 and 58 years (mean age, 45.5 years). The sites of pressure sore were in the ischial and trochanteric areas. Heterotopic ossification had developed around the hip joint and the ischial area. The mean onset time was 3.6 years (minimum 10 months maximum 8 years) after trauma. Plain X-ray, bone scan CT and pathological examination were helpful in confirming the diagnosis of heterotopic ossification. The mechanism of heterotopic ossification is not exactly known, but chronic trauma or inflammation could be one etiology. There are still many difficulties in management of heterotopic ossification, but prevention is the most important treatment.
Diagnosis ; Femur ; Hip Joint ; Humans ; Inflammation ; Joints ; Male ; Ossification, Heterotopic* ; Pressure Ulcer* ; Wounds and Injuries

No abstract available.
Contracture* ; Mastectomy* ; Seroma*

No abstract available.

No abstract available.
Ductus Arteriosus, Patent*

BACKGROUND: For the evaluation of pulmonary nrtery branches after operation of right ventricular outflow obstructive disease, we reviewed the usefulness of both simple X-ray and lung perfusion scan with 99mTc-macroaggregated albumin compared with cardiac angiography. METHODS: From March, 1986 to July, 1993, at Seoul National University Children;s Hospital, we chose 23 cases who underwent both simple X-ray and cardiac angiography among the patients who had distinct difference between right and left pulmonary blood flow in lung perfusion scan after operation of right ventricular outflow obstructive disease. So we calculated the ratio of right and left pulmonary blood flow and Spearman correlation coefficient. RESULTS: Of the 23 cases, 17 cases were tetralogy of Fallot, 4 cases pulmonary atresia, 1 case double outlet right ventricle, and 1 case truncus arteriosus. The mean age at poeration was 27 months, and the mean postoperative follow-up period was for 68 months. The correlation coefficient between cardiac angiography and simple X-ray was 0.86(p<0.01), and that beteen cardiac angiography and lung perfusion scan was 0.80(p<0.01). CONCLUSION: The cardiac angiography has been known as the best diagnostic tool for the evaluation of pulmonary artery branches after operation of right ventricular outflow obstructive ddisease, but we proposed that the lung perfusion scan should be widely used because its results were similar with those of cardiac angiography.
Angiography ; Double Outlet Right Ventricle ; Follow-Up Studies ; Humans ; Lung* ; Perfusion* ; Pulmonary Artery* ; Pulmonary Atresia ; Seoul ; Tetralogy of Fallot ; Truncus Arteriosus

As the productive activities have vastly increased following industrialization and urbanization in the modem society, the resulting high mobility of people and goods have caused a sharp increase in the accidents in the work places as well as traffic accidents. In particular, deaths caused by injuries are generally concentrated in the economically active young peoples, producing incalculable losses to the society and nation as a whole. Advanced nations with superior medical care systems have succeeded in reducing incidents of such deaths by operating trauma centers. Especially noteworthy is the case of the United States where such specialized trauma centers have greatly contributed to reducing deaths from injuries in the non-urban areas with less access to medical facilities. At present Korea has no medical centers specializing in injuries. In large cities, the injuries are being treated tertiary medical facilities while in the provinces they are referred to small and medium-sized hospitals that constitute secondary medical facilities. Currently in Korea the Trauma patients are treated at general hospitals that consist of 726 secondary medical facilities and 40 tertiary medical centers nationwide. The secondary medical facilities which tend to take most responsibility for the treatment of trauma are generally deficient in medical staff and facilities (including operating and intensive care facilities). Despite such deficiency and limitations, no regulations exist regarding treatment or transportation of trauma patients. This article reports the outcome of a comparative analysis of the results of trauma treatments among different types of medical facilities based on objective data in the hope that such study would facilitate a comparison with the treatment systems of advanced countries and thereby contribute to a precise formulation of problems that must be addressed in this area.
Accidents, Traffic ; Hope ; Hospitals, General ; Humans ; Critical Care ; Korea ; Medical Staff ; Modems ; Social Control, Formal ; Transportation ; Trauma Centers ; United States ; Urbanization ; Workplace ; Industrial Development