Psoriasis vulgaris is a common skin disease usually affects the traumatic joints and scalp in young adult. I reviewi 14l6 patients and the results were as follows; 1. Sex incidence was 991 in male and 425 in female(2.3: 1). 2. The peak age at onset of disease was between from 11 to 80 year of age. 3. The onset of psoriasis showed higher incidence in summer and lower in autumn. 4. Sites affected by psoriasis were most frequent in elbow joint(31.8%), 5. Koebner Phenomenon was found in 12.9% and the incubation period was 16 days on the average. 6. Family incidence was found in 198 cases(13.9%). 7. Joint pain was associated in 155 cases(10.9%), mainly in knee joint. 8. Nail involvement was in 84 cases(5.9). 9. Mucous membrane involvement was in 103 cases(7. 2% ). 10. Other skin diseases in those study were variable but the predominated in neurodermatitis, ll. A significant difference between man and woman for the medication, man was treated by specialist while the woman was medicated by pharmacist advised 12. Approximately half of the cases(56.6%) were ignorant for psoriasis. 13. A significant difference between man and woman about psychiatric problem, was observed. The man had a sought of incurability while the woman had anxiety for the life threaten.
Anxiety ; Arthralgia ; Elbow ; Female ; Humans ; Incidence ; Joints ; Knee Joint ; Male ; Mucous Membrane ; Neurodermatitis ; Pharmacists ; Psoriasis* ; Scalp ; Skin Diseases ; Specialization ; Young Adult

Nevus lipomatosus cutaneous superficialis(NLCB) is a rare condition consisting of ectopic fat tissue in the dermis and having the predilection for the pelvic girdle, especially gluteal region. The patient was a 20 year-old female. About 8 years prior to the first visit she had noticed the rice-sized papules on her lower back, which had been gradually increased in size and coalesced to become two, cerebriform, skin colored to yellowish tumor masses of soft consistency, distributed on both sides of the midline of lower back, and measuring respectively 3.5X7.Qcm and 7.0x11.5cm in size. Jihe biopsy specimen taken from the tumor mass revealed the ectopic presence of fat lobules occupying half of the reticular dermis. The fat lobules consisted of almost mature fat cells with the presence of dilated capillaries in their centers.
Adipocytes ; Biopsy ; Buttocks ; Capillaries ; Dermis ; Female ; Humans ; Nevus* ; Skin ; Young Adult

No abstract available.
Animals ; Diuresis* ; Heat-Shock Proteins ; HSP70 Heat-Shock Proteins* ; Rats* ; Urinary Bladder*

Dermal melanocytosis includes Mongolian spot, nevi of Ota and Ito, dermal melanocytic harnartoma, and blue nevus. Nevi of Ota may be respectively associated with Mongolian spot, blue nevi and unilateral or bilateral nevi of Ito. We present a case, a 24 year-old female, who had bilaterally brownish or slatebluish pigmented patches on the face, sclera, neck, anterior chest, deltoid, supraclavicular, scapular, back and sacrococcygeal area. And also she had a bluish, bean-sized nodule on her left mid-back. It is likely that this case may be considered as an extremely extensive case of pig:m.entary anomaly, associating aberrant and persistent mongolian spots, extensive nevus of Ito, bilateral nevus of Ota and blue nevus. To our knowledges it seems that such case has not previously been reported in Korean literature.
Female ; Humans ; Mongolian Spot ; Neck ; Nevus ; Nevus of Ota ; Nevus, Blue ; Sclera ; Thorax ; Young Adult

We experienced a 40-year-old female patient who had vegetating plaques, erosions and a few vesicles on the external genitalia and the oral mucasa, assoeiated with pulmonary tuberculosis. On the skin biopsy specimen of the vegetating plaque, it showed acanthoais, papillomatosis, downward proliferation of the epidermis and eosinophilic microabacess in the epidermis. Direct immunofluorescence of the perilesional skin revealed deposition of IgG, Cq, Cs and C on the intercellular substance of the epidermis. Indirect immunofluorescence disclosed IgCi auto antibody(1: 320) positive to the inter ellular substance of the normal human back skin. The skin lesion had impraved with dapsone therapy.
Adult ; Biopsy ; Dapsone ; Eosinophils ; Epidermis ; Female ; Fluorescent Antibody Technique, Direct ; Fluorescent Antibody Technique, Indirect ; Genitalia ; Humans ; Immunoglobulin G ; Papilloma ; Pemphigus* ; Skin ; Tuberculosis, Pulmonary

No abstract available.
Cardiomyopathy, Dilated*

It is commonly believed that the branchial anomalies are persistent remnants of the embryologic branchial apparatus. These anomalies are originated from branchial cleft and most commonly involved in second branchial deft. Clinically they present palpable mass, discharge from fistula, recurrent infection due to obstruction of Gstula tract. As respiratory symptoms, they may present hoarseness, preceeded by or associated with upper respiratory infection. However, it has not been reported that they caused airway obstruction in newborn infants. Wc experienced a case of the fourth branchial deft cyst in a 2 day old infant who showed respiratory difficulty due to airway obstruction.
Airway Obstruction ; Branchial Region* ; Branchioma* ; Fistula ; Hoarseness ; Humans ; Infant ; Infant, Newborn

We report herein a human sparganosis that presented confusing features in aspect of its correct identification, The patient was 35-year-old man who had a past history of eating fried frogs since 3 years prior to his first admission in 198I. Three mature Sparganum mansoni and 69 encapsulated spargana pieces were excised from his left inguinal area, left thigh and scrotum by three consecutive operations in 19 months. The encapsulated spargana were irregular in shape and size and mummified. They were identified histopathologically as degenerated spargana by no sexual organs and many calcareous bodies in the parenchyma. Differentiation of our case from proliferating sparganosis caused by Spargarrum proliferum was discussed.
Adult ; Eating ; Humans ; Scrotum ; Sparganosis* ; Sparganum ; Thigh

To investigate the cellular immune response in myasthenia gravis (MG), serum levels of interleukin-2(IL-2), soluble IL-2 receptor(sIL-2R) and neopterin were measured in 48 patients with MG, and these levels were compared with those in 22 healthy controls Also, the relationship of serum levels of IL-2. sIL-2R and neopterin to disease severity and thymic histology, and the changes of above laboratory indexes were observed according to thymectomy. Serum IL-2 was not detected in controls. But was detected in 56% of MG patients. Mean levels of serum sIL-2R were significantly increased in MG patients compared with controls (p<0.01), and mean levels of serum neopterin were increased, but not statistically significant in MG patients compared with controls. Mean levels of serum sIL-2R were significantly increased in the groups of grade IIB and m compared with the groups of grade I and IIA(p<0.01) Among 20 thymectomized MG patients, mean levels of serum sIL-2R were significantly increased in patients with thymoma compared with those with involuted thymus(p<0.05). In the follow-up study of serum levels of IL-2, slL-2R and neopterin after thymectomy, the detection rate of serum IL-2 was significantly decreased in patients more than 1 year after thymectomy compared with those before thymectomy (P<0.05), and mean levels of serum sIL-2R and neopterin were significantly decreased in patients more than 1 year after thymectomy compared with those before thymectomy (P< 0.01, p<0.05). These decrements reflected the clinical improvement. These results suggest that the cellular immune responses with T cell and macrophage activation are relevant to the pathogenesis of MG. Serum sIL-2R level is correlated with disease severity, and serum IL-2, sIL-2R and neoptrin levels may represent markers of disease activity after thymectomy.
Follow-Up Studies ; Humans ; Immunity, Cellular ; Interleukin-2 ; Macrophage Activation ; Myasthenia Gravis* ; Neopterin ; Thymectomy ; Thymoma

OBJECTIVE: The treatment modalities of cerebral aneurysms mainly consist of surgical neck clipping of aneurysms and endovascular embolization. Through comparing of the treatment results between two methods especially focused on their complicatons, the authors present the efficacy of the treatment modality in ruptured middle cerebral artery aneurysms. METHODS: Patients who admitted due to ruptured middle cerebral artery aneurysm between January 1998 and December 2002 were selected. They have done surgical neck clipping or endovascular embolization which employed platinum coil. Treatment methods were chosen in random fashion. The patient's clinical state were determined before, during, and after the treatment by using Hunt and Hess grade and Glasgow outcome scale(GOS). According to Fisher grade was classified based on the amount of hemorrhage. Statistical analyses were done with Student t-test, Pearson's correlation coefficient, and Mann-Whitney U test. RESULTS: Average follow-up period was 24 months(5 days-36 months) in surgery group and 26 months(8 days-36 months) in endovascular embolization group. There was no statistical significance regard to sex, age, patient's Hunt and Hess grade on admission, the Fisher grade, and aneurysmal size. There was no significant difference between GOS of two groups in statistically(p>0.05). CONCLUSION: This comparative study of reveals no significant difference in neurologic outcomes between two treatment modalities.
Aneurysm ; Follow-Up Studies ; Hemorrhage ; Humans ; Intracranial Aneurysm* ; Middle Cerebral Artery* ; Neck* ; Platinum