1.Effect of platelet activating factor on the secretion of progesterone in the rabbit.
Soo Hyun CHO ; Sung Ro CHUNG ; Yeoun Young HWANG ; Hyung MOON
Korean Journal of Fertility and Sterility 1992;19(1):9-14
No abstract available.
Blood Platelets*
;
Platelet Activating Factor*
;
Progesterone*
2.A Lethal Case of Sodium Azide Ingestion.
Yeoun Woo NAM ; Jung Eon KIM ; Junho CHO ; Sung Pil CHUNG ; Hahn Shick LEE ; Eui Chung KIM
Journal of The Korean Society of Clinical Toxicology 2008;6(1):49-51
Sodium azide (NaN3) is a white to colorless, crystalline powder that is highly water soluble, tasteless, and odorless. It is used mainly as a preservative in aqueous laboratory reagents and biologic fluids and also as an automobile airbag gas generant. Although it has caused deaths for decades, the toxic properties and effects of sodium azide in humans remains unknown. A 31-year-old comatose female was transported to the emergency department with an empty bottle labeled sodium azide. She developed cardiac arrest 15 minutes after arrival and expired in spite of 30 minutes of resuscitative effort. Subsequently, resuscitation team members incidentally suffered from sodium azide's exposure and developed eye discomfort, skin rashes parasthesias, pruritus, sore throat, and headache.
Adult
;
Air Bags
;
Automobiles
;
Coma
;
Crystallins
;
Eating
;
Emergencies
;
Exanthema
;
Eye
;
Female
;
Headache
;
Heart Arrest
;
Humans
;
Indicators and Reagents
;
Pharyngitis
;
Pruritus
;
Resuscitation
;
Sodium
;
Sodium Azide
3.Stress Induced Cardiomyopathy after Local Epinephrine Use: A case report.
Choon Kyu CHO ; Sung Mee JUNG ; Joong Yeoun KIM ; Hee Uk KWON ; Po Soon KANG
Korean Journal of Anesthesiology 2008;54(5):581-584
Epinephrine is frequently used to control local bleeding during surgery. However, it may be associated with complications, such as pulmonary edema, reversible cardiomyopathy, and cardiac arrest. We encountered a case of stress induced cardiomyopathy (SIC) after local epinephrine instillation. The SIC is manifested with typical left ventricular apical ballooning and clinical symptoms of a myocardial infarction without coronary stenosis. Although its prognosis is more favorable than a myocardial infarction, anesthesiologists need to be aware of the possible adverse effects of local epinephrine infiltration.
Cardiomyopathies
;
Coronary Stenosis
;
Epinephrine
;
Heart Arrest
;
Hemorrhage
;
Myocardial Infarction
;
Prognosis
;
Pulmonary Edema
4.Exercise tolerance tests in patients with tetralogy of Fallot repaired earlier: correlation with 2-dimensional echocardiography and cardiac catheterization.
Jin Yong LEE ; Jun Hee SUL ; Sung Kyu LEE ; Dong Shik CHIN ; Bum Koo CHO ; Soo Kwan HWANG ; Dong Soo YEOUN
Journal of the Korean Pediatric Society 1992;35(2):157-167
No abstract available.
Cardiac Catheterization*
;
Cardiac Catheters*
;
Echocardiography*
;
Exercise Tolerance*
;
Humans
;
Tetralogy of Fallot*
5.Peripheral type squamous cell carcinoma of the lung: clinicopathologic characteristics in comparison to the central type
Yeoun Eun SUNG ; Uiju CHO ; Kyo Young LEE
Journal of Pathology and Translational Medicine 2020;54(4):290-299
Background:
Squamous cell carcinomas (SqCCs) of the lung are known to arise more often in a central area but reports of peripheral SqCCs have increased, with a pathogenesis that is obscured. In this study, the clinicopathologic characteristics of peripheral lung SqCCs were studied and compared with those of the central type.
Methods:
This study included 63 peripheral lung SqCCs and 48 randomly selected central cases; hematoxylin and eosin-stained slides of surgically resected specimens were reviewed in conjunction with radiologic images and clinical history. Cytokeratin-7 immunohistochemical staining of key slides and epidermal growth factor receptor (EGFR)/KRAS mutations tested by DNA sequencing were also included.
Results:
Stages of peripheral SqCCs were significantly lower than central SqCCs (p=.016). Cystic change of the mass (p=.007), presence of interstitial fibrosis (p=0.007), and anthracosis (p=.049) in the background lung were significantly associated with the peripheral type. Cytokeratin-7 positivity was also higher in peripheral SqCCs with cutoffs of both 10% and 50% (p=.011). Pathogenic mutations in EGFR and KRAS were observed in only one case out of the 72 evaluated. The Cox proportional hazard model indicated a significantly better disease-free survival (p=.009) and the tendency of better overall survival (p=.106) in the peripheral type.
Conclusions
In peripheral type, lower stage is a favorable factor for survival but more frequent interstitial fibrosis and older age are unfavorable factors. Multivariate Cox analysis revealed that peripheral type is associated with better disease-free survival. The pathogenesis of peripheral lung SqCCs needs further investigation, together with consideration of the background lung conditions.
6.Second-tier Instruction of Cardiopulmonary Resuscitation by CPR Anytime(R) Trainees.
Yeoun Woo NAM ; Sung Pil CHUNG ; Jun Ho CHO ; Hyun Soo CHUNG ; Hahn Shick LEE ; Jai Woog KO ; Eui Chung KIM ; Jin Hee LEE
Journal of the Korean Society of Emergency Medicine 2008;19(3):282-287
PURPOSE: CPR Anytime(R), a self-instructional video program, has gained popularity amongst CPR instructors for training non-healthcare providers. This instructional kit enables second-tier instruction. The purpose of this study is to determine the status of second-tier instruction CPR by CPR Anytime(R) trainees. METHODS: Questionnaires were sent to 606 CPR Anytime(R) trainees from 12 BLS training sites. The training period was from October 2006 to July 2007. Questionnaires included provider's basic information, post-course self exercise, amount of second-tier instruction, and multiplier status. RESULTS: The response rate of the questionnaire was 53.6%(325). The mean age was 20.4+/-10.3 years old. The professions of respondents were as follows: students (76.3%), office workers(13.2%), teachers(4.4%), and service providers(1.9%). The post-course self exercise rate was 49% with three fourths of those completing the exercises using both the DVD and MiniAnne(R). Second-tier instruction tools use rates(48%) were as follows: DVD and manikin(35%), manikin only(9%), verbal only(2%), and DVD only(1%). The total multiplier effect was 1.77(575/ 325) with the multiplier effect of teachers significantly higher than others. CONCLUSION: This study found that 48% of CPR Anytime(R) providers perform second-tier instruction to family and friends. Amongst them, the total multiplier effect was 1.77 (575/325).
Cardiopulmonary Resuscitation
;
Surveys and Questionnaires
;
Exercise
;
Friends
;
Humans
;
Manikins
7.A case of Budd-Chiari syndrome with high antiphospholipid antibody in a patient with systemic lupus erythematosus.
Yeoun Yeon YUN ; Kyung Ah YOH ; Hyoung In YANG ; Sung Hwan PARK ; Sang Heon LEE ; Chul Soo CHO ; Ho Youn KIM
The Korean Journal of Internal Medicine 1996;11(1):82-86
Antiphospholipid syndrome is characterized by recurrent episodes of arterial and venous thrombosis, spontaneous fetal losses, thrombocytopenia and persistently elevated levels of antiphospholipid antibodies. We experienced a case of Budd-Chiari syndrome in a 32-year old female lupus patient who was presented with left leg edema, ascites and esophageal varix. The clinical and laboratory findings were compatible with the cirteria for systemic lupus erythematosus (SLE) and she was found to have anticardiolipin antibody, thrombocytopenia and prolonged partial thromboplastin time. Initially, she was treated with intravenous heparin and uroki nase and she was followed up with warfarin, baby aspirin and steroids.
Adult
;
Angiography
;
Animal
;
Antibodies, Antiphospholipid/blood*
;
Case Report
;
Drug Therapy, Combination
;
Female
;
Hepatic Vein Thrombosis/complications
;
Hepatic Vein Thrombosis/diagnosis*
;
Hepatic Vein Thrombosis/drug therapy
;
Human
;
Lupus Erythematosus, Systemic/complications
;
Lupus Erythematosus, Systemic/diagnosis*
;
Lupus Erythematosus, Systemic/drug therapy
;
Tomography, X-Ray Computed
8.Comparison of vertical infraclavicular brachial plexus block with 0.5% levobupivacaine and 0.5% ropivacaine for upper limb surgery.
Choon Kyu CHO ; Joong Yeoun KIM ; Sung Mee JUNG ; Hee Uk KWON ; Po Soon KANG ; Chul Woung KIM ; Jeong Uk HAN ; Chun Woo YANG
Korean Journal of Anesthesiology 2009;56(2):162-168
BACKGROUND: We performed a prospective, double blind study to compare the clinical effect of vertical infraclavicular brachial plexus block produced by 0.5% levobupivacaine and 0.5% ropivacaine for upper limb surgery. METHODS: We included 60 patients receiving upper limb surgery under infraclavicular brachial plexus block. The infraclavicular brachial plexus block was performed via the vertical technique with 30 ml of 0.5% levobupivacaine or 0.5% ropivacaine. We observed which nerve type was stimulated and scored the sensory and motor block. The quality of block was assessed intraoperatively. The duration of sensory and motor block and complications were assessed. RESULTS: There were no significant differences in frequencies of stimulated nerve type, evolution of sensory and motor block quality, or success of block. There were no significant difference in duration of sensory block, but duration of motor block was prolonged after 0.5% levobupivacaine. There were no complications. CONCLUSIONS: Both 0.5% levobupivacaine and 0.5% ropivacaine had similar effects in the vertical infraclavicular brachial plexus block.
Amides
;
Brachial Plexus
;
Bupivacaine
;
Double-Blind Method
;
Humans
;
Prospective Studies
;
Upper Extremity
9.Tumor Necrosis Factor-alpha Gene Polymorphisms in Korean Children with Inflammatory Bowel Disease.
Min Sung CHO ; Seung Min SONG ; Seak Hee OH ; Yeoun Joo LEE ; Ju Young JANG ; Kyung Mo KIM
Korean Journal of Pediatric Gastroenterology and Nutrition 2011;14(3):269-278
PURPOSE: The aim of this study was to investigate the existence of TNF-alpha polymorphisms in Korean children with Crohn's disease (CD), ulcerative colitis (UC), as compared to healthy controls. METHODS: Blood samples were obtained from 40 patients with CD, 14 patients with UC, and 30 healthy controls. Genotyping for 5 TNF-alpha polymorphisms (G238A, G308A, C857T, C863A, and T1031C) was performed. The allele frequencies for the inflammatory bowel diseases, CD and UC, were measured in patients with these disease and in healthy controls, and these allele frequencies were compared between the 3 groups. We examined the significant association between polymorphism and disease phenotype, such as location, behavior, perianal disease, and pediatric Crohn's activity index (PCDAI) in CD. RESULTS: Based on our findings, the TNF-alpha allele frequencies of G238A, G308A, C857T, C863A, and T1031C were 3.3, 8.3, 16.7, 16.7, 21.7% in healthy control, 2.5%, 7.5%, 18.8%, 20.0%, 22.5% in CD, 7.1%, 7.1%, 7.1%, 21.4%, 28.6% in UC. They were no statistically significant differences between the 3 groups. There were no associations between genotypes and phenotypes in CD, except a statistically significant higher allele frequency of G238A in ileal type (L1) disease (p=0.010). CONCLUSION: Our results indicate that 5 TNF-alpha polymorphisms do not seem to be associated with susceptibility to inflammatory bowel disease in Korean pediatric patients even though young patients were anticipated to have a stronger genetic affiliation for these diseases than adult patients. We think that further studies are needed to find those genes associated with susceptibility to CD and UC in Korean pediatric patients with inflammatory bowel disease.
Adult
;
Child
;
Colitis, Ulcerative
;
Crohn Disease
;
Gene Frequency
;
Genotype
;
Humans
;
Inflammatory Bowel Diseases
;
Phenotype
;
Tumor Necrosis Factor-alpha
10.Two Cases of Scrub Typhus Presenting with Guillain-Barre Syndrome with Respiratory Failure.
Il Nam JU ; Jung Woo LEE ; Sung Yeoun CHO ; Seung Jee RYU ; Youn Jeong KIM ; Sang Il KIM ; Moon Won KANG
The Korean Journal of Internal Medicine 2011;26(4):474-476
No abstract available.
Diagnosis, Differential
;
Doxycycline/therapeutic use
;
Female
;
Guillain-Barre Syndrome/*diagnosis/pathology
;
Humans
;
Immunoglobulins/therapeutic use
;
Male
;
Middle Aged
;
Respiration, Artificial
;
Respiratory Insufficiency/*diagnosis/pathology
;
Scrub Typhus/*diagnosis/pathology