1.Surgical Treatment of Involutional Entropion.
Wha Sun CHUNG ; Sung Wook JEON
Journal of the Korean Ophthalmological Society 1992;33(1):18-22
The orbicularis oculi muscle transpositions with horizontal shortening procedures were performed for involutional entropion of the fourteen lower eyelids in twelve patients. The age ranged from 51 to 84 years (average 66.9 years). One patient was man and eleven patients were women. All patients were satisfactory with good cosmesis and improvement of tearing, discharge and ocular pain etc. after the follow-up period of 6 to 26 months. But mild subcutaneous hematoma of the eyelid was noticed in 3 cases with good absorption.
Absorption
;
Entropion*
;
Eyelids
;
Female
;
Follow-Up Studies
;
Hematoma
;
Humans
2.Prognosis of extraventricular drainage in childhood tuberculous meningits.
Hye Jeong JEON ; Ki Joong KIM ; Tae Sung KO ; Dong Wook KIM ; Yong Seung HWANG
Journal of the Korean Child Neurology Society 1993;1(1):72-82
No abstract available.
Drainage*
;
Prognosis*
3.The Mid-Term Efficacy and Safety of a Permanent Nitinol IVC Filter (TrapEase) .
Wei Chiang LIU ; Young Soo DO ; Sung Wook CHOO ; Dong Ik KIM ; Young Wook KIM ; Duk Kyung KIM ; Sung Wook SHIN ; Kwang Bo PARK ; Yong Hwan JEON ; In Wook CHOO
Korean Journal of Radiology 2005;6(2):110-116
OBJECTIVE: 1) To evaluate the mid-term efficacy and safety of a permanent nitinol inferior vena cava (IVC) filter; 2) to evaluate filter effectiveness, filter stability and caval occlusion. MATERIALS AND METHODS: A prospective evaluation of the TrapEase IVC filter was performed on 42 patients (eight men, 34 women) ranging in age from 22 to 78 years (mean age 66 years). All patients were ill with a high risk of pulmonary embolism (PE). Indications for filter placement were: 1) deep vein thrombosis with recurrent thromboembolism; 2) and/or free-floating thrombus with contraindication to anticoagulation; and 3) complications in achieving adequate anticoagulation. Follow-up evaluations (mean: 15.4 months, range: 2 to 28 months) were performed at 6- and 12-month intervals after the procedure and included clinical histories, chart reviews, plain film, Doppler ultrasounds, and contrasted abdominal CT scans. RESULTS: In follow-up evaluations, the data analysis revealed no cases of symptomatic PE. There were no cases of filter migration, insertion site thrombosis, filter fracture, or vessel wall perforation. During the study, there was one case of filter thrombosis; early symptomatic thrombosis that was successfully treated in the hospital. Of the 42 subjects, eight died. These deaths were not related to the filter device or the implantation procedure, but to the underlying disease. CONCLUSION: This study demonstrates that the TrapEase permanent IVC filter is a safe and an effective device with low complication rates and is best used in patients with thromboembolic disease with a high risk of PE.
Adult
;
Aged
;
*Alloys
;
Equipment Design
;
Female
;
Follow-Up Studies
;
Humans
;
Male
;
Middle Aged
;
Prospective Studies
;
Pulmonary Embolism/*prevention & control
;
Safety
;
Thromboembolism/complications
;
Treatment Outcome
;
*Vena Cava Filters
;
Vena Cava, Inferior
;
Venous Thrombosis/*complications
4.Determinants of Left Ventricular Mass in Healthy Adults : A Study Using Echocardiography and 24 Hour Ambulatory Blood Pressure Monitoring.
Ho Choon JEON ; Young Kwon KIM ; Kyeong Young KIM ; Ji Young KIM ; Sung Eun CHA ; Seong Wook CHO ; In SOHN
Korean Circulation Journal 1995;25(4):811-819
BACKGROUND: Echocardiographically detected left ventricular(LV) hypertrophy is a risk factor for cardiovascular morbidity and mortality. A better understanding of the determinants of LV mass may aid in strategies directed toward the promary and secondary prevention of LV hypertrophy and its consequences. Previous studies have reported that male gender, arterial blood pressure(BP), obesity, age, aortic valvular stenosis, dietary sodium, endocrine factors, and physical activity are positively correlated with LV mass. Of these determinants male gender, hypertension, and obesity are well known but age and blood pressure in healthy adults are controversial. To assess the determinants of LV mass, the relation of 2-dimensional(2D) echocardiographically determined LV mass to body mass inedx(BMI), age, sex, casual BP, and 24 hour ambulatory blood pressure(ABP : systolic, diastolic, and mean BP of 24 hour, day-time, and night-time) was examined in healthy adults. METHODS: The study population consisted of 200 healthy adults who were normotensive, nonobese, and had no evidence of cardiovascular disease(range in age from 20 to 69 years, five decades, 20 men and 20 women per each decade). LV mass was derived from area length method measurements obtained by 2D echocardiography and corrected for height. ABP monitoring was performend over 24 hour(divided into day-time(6am-10pm) and night-time(10pm-6am)periods) with 30 minute inervals. RESULTS: 1) BMI was significantly and independently related to LV mass corrected for height (p<0.001, partial R2=0.31 in men and 0.43 in women). An increase of BMI by 1 kg/m2increased LV mass corrected for height by 1.9g/m in men and 2.0g/m in women. 2) Age was significantly and independently related to LV mass corrected for height(p<0.001, partial R2=0.15 in men and 0.17 in women). The increments of Lv mass corrected for height per decade were 2.1 g/m in men and 3.4 g/m in women. 3) Gender was significantly and independently related to LV mass corrected for height(p<0.001, partial R2=0.12), which was greater in men than in women by 6.34g/m. 4) Casual Bp and 24 hour ABP were not significantly associated with LV mass corrected for height in total population and women, and 24 hour systolic BP was significantly related to LV mass corrected for height only in men(p<0.001) with weak partial R2(0.05). CONCLUSION: BMI, age, and male gender were statistically significant and independent correlates of LV mass corrected for height(p<0.001). Maintenance of ideal body weight and normal BP, weight reduction in obese persons and BP control inhypertensive patients may contribute to the primary and secondary prevention of LV hypertrophy and its sequalae.
Adult*
;
Blood Pressure
;
Blood Pressure Monitoring, Ambulatory*
;
Constriction, Pathologic
;
Echocardiography*
;
Female
;
Humans
;
Hypertension
;
Hypertrophy
;
Ideal Body Weight
;
Male
;
Mortality
;
Motor Activity
;
Obesity
;
Risk Factors
;
Secondary Prevention
;
Sodium, Dietary
;
Weight Loss
5.Clinical analysis in reconstruction of orbital blow-out fracture using the hydroxyapatite.
Sung Ho HWANG ; Yong Chan BAE ; Jae Yong JEON ; So Min HWANG ; Wook Bae HWANG ; Dong Heon KIM
Journal of the Korean Society of Plastic and Reconstructive Surgeons 1998;25(6):1067-1074
The blow-out fracture can be reconstructed by various autogeneous and alloplastic material. Particulate, nonresorbable hydroxyapatite is currently one of the choice of implant material available for reconstruction of blow-out fracture. Hydroxyapatite is radiopaque ceramic, physically and chemically similar to enamel and cortical bone. It is a biomaterial derived from natural corals to use as a bone graft substitute. And we looked into the clinical usefulness of 2 type of hydroxyapatite with their advantages and disadvantages in reconstruction of blow-out fracture. 183 patients with blow-out fracture who underwent surgical reconstruction with two types of hydroxyapatite from March 1933 to July 1977 have been analyzed the results of surgical reconstructions, and have been followed up for more than a year. And the condition of formerly inserted hydroxyapatite was observed in the patients who needed 2nd surgical reconstruction due to the enophthalmos. The disadvantages of hydroxyapatite are fragility, size and contour limitations. In spite of these demerits, hydroxyapatite can be one of the prospective materials to reconstruct orbital floor. Through the clinical experiences for 5 years, we have not found any of complications of exposure, infection, and foreign body reaction. Low rates of diplopia, limitation of ocular movement, and enophtalmos was observed. Hydroxyapatite was well adherent to adjacent orbital bone in most patients who needed secondary reconstruction for enopthalmos. In conclusion, our study shows that the availability of hydroxyapattite in reconstruction of blow-out fracture is recommendable, with low complication rates. Hydroxyapatite important appears to be well tolerated, and provides useful alloplastic prosthesis with few problems in reconstruction of blow-out fracture.
Anthozoa
;
Ceramics
;
Dental Enamel
;
Diplopia
;
Durapatite*
;
Enophthalmos
;
Foreign-Body Reaction
;
Humans
;
Orbit*
;
Orbital Fractures*
;
Prostheses and Implants
;
Transplants
6.Effect of tribochemical silica coating on the shear bond strength of rebonded monocrystalline ceramic brackets.
Young Mi JEON ; Woo Sung SON ; Sang Wook KANG
Korean Journal of Orthodontics 2010;40(3):184-194
OBJECTIVE: The purpose of this study was to investigate the effect of tribochemical silica coating on the shear bond strength (SBS) of rebonded ceramic brackets using nano-filled flowable composite resin. METHODS: A total of 60 premolars were prepared and divided into 4 equal groups as follows: Tribochemical silica coating (TC) + Transbond XT (XT), TC + Transbond supreme LV (LV), Sandblast treatment (SA) + XT, SA + LV. Treated ceramic brackets were rebonded on the premolars using each adhesive. All samples were tested in shear mode on a universal testing machine. RESULTS: SBS of silica coated groups were high enough for clinical usage (TCLV: 10.82 +/- 1.82 MPa, TCXT: 11.50 +/- 1.72 MPa). But, SBS of the sandblast treated groups had significantly lower values than the tribochemical silica coated groups (SALV, 1.23 +/- 1.16 MPa; SAXT, 1.76 +/- 1.39 MPa; p< 0.05). There was no difference between the shear bond strength by type of adhesive. In the silica coated groups, 77% of the samples showed bonding failure in the adhesive. In the sandblast treated group, all bonding failures occurred at the bracket-adhesive interface. CONCLUSIONS: The result of this study suggest that newly introduced nano-filled flowable composite resin and tribochemical silica coating application on debonded ceramic bracket bases can produce appropriate bond strengths for orthodontic bonding.
Adhesives
;
Bicuspid
;
Bisphenol A-Glycidyl Methacrylate
;
Ceramics
;
Collodion
;
Composite Resins
;
Resin Cements
;
Silicon Dioxide
7.Stomach Cancer Secondary to Hematologic Diseases.
Ji Hoon KIM ; Sung Bae JEE ; Hoon HUH ; Hyung Min CHIN ; Wook KIM ; Dong Wook KIM ; Jong Wook LEE ; Woo Sung MIN ; Choon Choo KIM ; Hae Myung JEON
Journal of the Korean Gastric Cancer Association 2007;7(4):237-241
PURPOSE: Patients with hematologic diseases such as chronic myeloid leukemia (CML) or chronic lymphoid leukemia (CLL) are known to have an increased chance of acquiring a secondary neoplasm. Stomach cancer is one of the most common malignant diseases in Korea, and we investigated whether the incidence of secondary stomach cancer in patients with a hematologic disease increases, in order to determine if a more intensive screening program for detecting secondary gastric cancer was required. We also investigated the safety of performing a gastrectomy in hematologic disease patients. MATERIALS AND METHODS: From 1992 to 2006, the medical records of 8376 patients diagnosed with one of the six common hematologic diseases were reviewed. RESULTS: Nine secondary stomach cancers were found among the 8376 patients during the 15-year observation period. No surgical-related complications occurred, and there was no recurrence of stomach cancer if detected early. CONCLUSION: It seems that a more intensive screening program for detecting secondary gastric cancer in hematologic disease patients is not required, and surgery is not risky in these patients.
Gastrectomy
;
Hematologic Diseases*
;
Humans
;
Incidence
;
Korea
;
Leukemia
;
Leukemia, Lymphoid
;
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
;
Mass Screening
;
Medical Records
;
Recurrence
;
Stomach Neoplasms*
;
Stomach*
8.Ethanol Embolization of Arteriovenous Malformations: Results and Complications of 33 Cases.
Yong Hwan JEON ; Young Soo DO ; Sung Wook SHIN ; Wei Chiang LIU ; Jae Min CHO ; Min Hee LEE ; Dong Ik KIM ; Byung Boong LEE ; Sung Wook CHOO ; In Wook CHOO
Journal of the Korean Radiological Society 2003;49(4):263-270
PURPOSE: To assess the effectiveness of ethanol embolization for the treatment of arteriovenous malformation (AVM), and the complications, if any, arising. MATERIALS AND METHODS: Thirty-three patients with AVMs underwent 145 staged sessions of ethanol embolization. AVMs were located in an upper extremity (n=14), a lower extremity (n=10), the pelvis (n=7), the thorax (n=1), or the abdomen (n=1). Eighty-five transcatheter embolizations and 60 direct percutaneous puncture embolizations were performed, and seven patients underwent additional coil embolization of the dilated outflow vein. The therapeutic effectiveness of embolization was evaluated in terms of the extent to which an AVM was obliterated between baseline and the final angiogram. Complications were classified as minor or major. RESULTS: In 13 patients (39%), AVMs were totally obliterated. In eitht patients (24%), more than 75% were obliterated; in three (9%), the proportion was 50-75%; and in four (12%), less than 50%. Five patients (15%), were not treated. The reasons for failure were the difficulty of approaching the nidus due to previous surgical ligation or coil embolization of the feeding artery, the subcutaneous location of an AVM, post-procedural infection, and massive bleeding during the follow-up period. Twenty-one minor complications such as focal skin necrosis or transient nerve palsy developed during 145 sessions of (an incidence of 14%), but these were relieved by conservative treatment. The five major complications arising (3%) were cerebral infarction, urinary tract infection, acute renal failure due to rhabdomyolysis, permanent median nerve palsy, and infection. CONCLUSION: Ethanol embolization by direct percutaneous puncture or using a transcatheter technique is an effective approach to the treatment of an AVM. However, to overcome the considerable number of complications arising, further investigation is required.
Abdomen
;
Acute Kidney Injury
;
Arteries
;
Arteriovenous Malformations*
;
Cerebral Infarction
;
Embolization, Therapeutic
;
Ethanol*
;
Follow-Up Studies
;
Hemorrhage
;
Humans
;
Incidence
;
Ligation
;
Lower Extremity
;
Median Nerve
;
Necrosis
;
Paralysis
;
Pelvis
;
Punctures
;
Rhabdomyolysis
;
Skin
;
Thorax
;
Upper Extremity
;
Urinary Tract Infections
;
Veins
9.Comparison of Pharmacokinetic Affinity of Various Non-depolarizing Neuromuscular Blocking Agents in the Isolated Foream.
Sung Keun LEE ; Yong Sup JEON ; Jun Suk AHN ; Kyung Ho HWANG ; Wook PARK ; Sung Yell KIM
Korean Journal of Anesthesiology 1995;28(6):816-820
It is well known that the plasma concentration is important in determining the rate of recovery from neuromuscular block. However, nondepolarizing neuromuscular blockade are retained at the neuromuscular junction and are not readily displaced in response of changes in plasma drug concentration, for instance, the neuromuscular block induced by mivacurium appears to considerably outlast the theoretical plasma half-life of the drug and is continued long after the plasma level has fallen to subparalytic levels due to rapid metabolism by pseudocholinesterase. It has been suggested that although plasma concentration may be the key determinant of recovery from neuromuscular block, recovery will depend upon the dissociation from the affinity of drug in the effect compartrnent and not upon its plasma concentration. In an attempt to confirm these evidences, we have investigated the response of changes in neuromuscular block after releasing tourniquet at 50% twitch depression using the isolated forearm experiment with various neuromuscular blocking agents. The results of this study demonstrated the further increase of block after early toumiquet release in the isolated forarm in all agents; 66+/-14% in vecuronium, 90+/-9% in atracurium, 92+/-7% in pancuronium, and 73+/-18% in mivacurium Conclusively, the further block continued to increase in spite of the negligible plasma drug concentration after early tourniquet release may be caused by more in affinity of drugs in binding sites than plasma drug concentration. Therfore, it is evident that both the affinity of drug to the receptor and the plasma drug concentration have influenced on the recovery from the neuromuscular block.
Atracurium
;
Binding Sites
;
Depression
;
Forearm
;
Half-Life
;
Metabolism
;
Neuromuscular Blockade*
;
Neuromuscular Blocking Agents*
;
Neuromuscular Junction
;
Pancuronium
;
Plasma
;
Pseudocholinesterase
;
Tourniquets
;
Vecuronium Bromide
10.Thrombotic Microangiopathy Score as a New Predictor of Neurologic Outcomes in Patients after Out-of-Hospital Cardiac Arrest
Je Sung YOU ; Hye Sun LEE ; Soyoung JEON ; Jong Wook LEE ; Hyun Soo CHUNG ; Sung Phil CHUNG ; Taeyoung KONG
Yonsei Medical Journal 2022;63(5):461-469
Purpose:
Given the morphological characteristics of schistocytes, thrombotic microangiopathy (TMA) score can be beneficial as it can be automatically and accurately measured. This study aimed to investigate whether serial TMA scores until 48 h post admission are associated with clinical outcomes in patients undergoing targeted temperature management (TTM) after out-of-hospital cardiac arrest (OHCA).
Materials and Methods:
We retrospectively evaluated a cohort of 185 patients using a prospective registry. We analyzed TMA scores at admission and after 12, 24, and 48 hours. The primary outcome measures were poor neurological outcome at discharge and 30-day mortality.
Results:
Increased TMA scores at all measured time points were independent predictors of poor neurological outcomes and 30-day mortality, with TMA score at time-12 showing the strongest correlation [odds ratio (OR), 3.008; 95% confidence interval (CI), 1.707–5.300; p<0.001 and hazard ratio (HR), 1.517; 95% CI, 1.196–1.925; p<0.001]. Specifically, a TMA score ≥2 at time-12 was closely associated with an increased predictability of poor neurological outcomes (OR, 6.302; 95% CI, 2.841–13.976; p<0.001) and 30-day mortality (HR, 2.656; 95% CI, 1.675–4.211; p<0.001).
Conclusion
Increased TMA scores predicted neurological outcomes and 30-day mortality in patients undergoing TTM after OHCA. In addition to the benefit of being serially measured using an automated hematology analyzer, TMA score may be a helpful tool for rapid risk stratification and identification of the need for intensive care in patients with return of spontaneous circulation after OHCA.