1.Two Cases of Pigmented Bowen's Disease.
Seon Wook HWANG ; Seon Wook HWANG ; Jung Wook KIM ; Sung Wook PARK ; Han Young WANG
Annals of Dermatology 2002;14(2):127-129
Pigmented Bowen's disease (PBD) is a rare variant of Bowen's disease(BD). Most of the reported cases showed pigmented patches or thin plaques. Thus its clinical manifestations may simulated other various pigmented skin lesions. We experienced 2 cases of PBD in patients with multiple BD developed after taking Korean proprietary pills (KPP, "Hwan-Yak"), which were suspected to contain certain amount of arsenics. Both patients also showed arsenical keratosis on their palms and soles. The darker pigmentation of the PBL led us to differentiated them from melanoma.
Bowen's Disease*
;
Humans
;
Keratosis
;
Melanoma
;
Pigmentation
;
Skin
2.A study for the isolation of the causative organism,antimicrobial susceptibility tests and therapeutic aspects in patients with impetigo.
Sung Wook PARK ; Han Young WANG ; Ho Suk SUNG
Korean Journal of Dermatology 1993;31(3):312-319
BACKGROUND: It is traditiqnally considered that the non-bullous fonn of impetigo is primarily of streptococcal origin and the bullous form is of staphylococcal origin. However, recent reports have shown that Staphylococcus aureus (SA) has become the predominant cauative pathogen of non-bullous impetigo as well as of bullous impetigo. Objective. Our purpose was to evaluate the predominant causativi. pathogen, and to establish a therapeutic guideline for impetigo. METHOD: We described the characteristics of lesions and gerformed bacterial culture and susceptibility tests in patients with impetigo. Patients were treatecl by one of three frequently used antibiotics(erythromycin, cefuroxime, fusidic acid). RESULTS: Of 77 patients, there were 47 cases of crusted type(61.9%), 18 cases of mixed type with crusted and bullous lesiona(23.3%), 7 cases of mixed type with crusted and pustular lesions(9.1%) and 5 cases of bullous type(6.6%). SA was grown from 90.1% af the cases, in 83.1% of cases it was the only organism to be foind and no gowth of streptococcus was faund even in mixed infections. An antimicrobial susceptibility test of 63 strains of SA demonstrated high susceptibility to vancomycin(98.4%), cefuroxime(97.1%), oxacillin(96.4%), cephalothin(95.2%), fusidic acid(91.7%) etc, and high resistance to penicillin(93.7%), gentamicin(90.5%), tobramycin(88.9%) and erythromicin(80.9%). Of 19 patients treated with erythrornycin, 12(63.1% ) showed treatment failure at a weeks, while no treatment failure occured in groups treated with cefuroxime and usidic acid. There were statistically significant differences iri therapeutic effect between cefuroxirne and erythromycin(P=0.005 by two tailedy test), and betweer fusidic acid and erythromycin(P=0.0040. But there was no significant difference between cefuroxime and fusidic acid. CONCLUSION: The predominant pathogen of non-bullous impetigo a well as bullous impetigo was SA which were highly resistant to erythromycin and highly sensitive to efuroxime and fusidic acid. In the clinical response, cefuroxinie and fusidic acid treatment were most effective and erythromycin was inadequate for treatment of impetigo.
Cefuroxime
;
Coinfection
;
Erythromycin
;
Furosemide
;
Fusidic Acid
;
Humans
;
Impetigo*
;
Staphylococcus aureus
;
Streptococcus
;
Treatment Failure
3.Analysis of World WideWeb-Based Queries on Alopecia: Conditions for Estabilishing an Efficient Telemedicine System.
Sung Wook PARK ; Sang Suck LEE ; Han Young WANG
Korean Journal of Dermatology 2000;38(5):629-634
No Abstract Available.
Alopecia*
;
Telemedicine*
4.A Case of Sezary Syndrome.
Sung Wook PARK ; Sang Suk LEE ; Seon Wook HWANG ; Han Young WANG
Korean Journal of Dermatology 2000;38(5):650-654
No Abstract Available.
Sezary Syndrome*
5.Extracorporeal Membrane Oxygenation for the Support of a Potential Organ Donor with a Fatal Brain Injury before Brain Death Determination.
Sung Wook CHANG ; Sun HAN ; Jung Ho KO ; Jae Wook RYU
Korean Journal of Critical Care Medicine 2016;31(2):169-172
The shortage of available organ donors is a significant problem and various efforts have been made to avoid the loss of organ donors. Among these, extracorporeal membrane oxygenation (ECMO) has been introduced to help support and manage potential donors. Many traumatic brain injury patients have healthy organs that might be eligible for donation for transplantation. However, the condition of a donor with a fatal brain injury may rapidly deteriorate prior to brain death determination; this frequently results in the loss of eligible donors. Here, we report the use of venoarterial ECMO to support a potential donor with a fatal brain injury before brain death determination, and thereby preserve donor organs. The patient successfully donated his liver and kidneys after brain death determination.
Brain Death*
;
Brain Injuries*
;
Brain*
;
Extracorporeal Membrane Oxygenation*
;
Humans
;
Kidney
;
Liver
;
Tissue and Organ Procurement
;
Tissue Donors*
6.A Case of Hereditary Epidermolytic Palmoplantar Keratoderma in Four Consecutive Generations.
Sung Wook PARK ; Seon Wook HWANG ; Jung Wook KIM ; Han Young WANG
Korean Journal of Dermatology 2001;39(2):231-234
We observed a family with 12 members in four consecutive generations affected by hereditary epidermolytic palmoplantar keratoderma(HEPPK). The affected family members demonstrated not only autosomal dominant inheritance, but also a high penetrance and constant expression. The lesion of all affected person had developed at birth or within the first few weeks of life. The lesions of three members(the proband, her sister and mother) were biopsed, and all of them showed the characteristic features of epidermolytic hyperkeratosis. Two of family members(the proband, her nephew-not affected by HEPPK) had vitiligo, but we concluded that this coexistance was accidental.
Family Characteristics*
;
Humans
;
Hyperkeratosis, Epidermolytic
;
Keratoderma, Palmoplantar, Epidermolytic*
;
Parturition
;
Penetrance
;
Siblings
;
Vitiligo
;
Wills
7.Two Cases of Occupational Radiodermatitis.
Sung Wook PARK ; Jung Wook KIM ; Seon Wook HWANG ; Han Young WANG
Korean Journal of Dermatology 2000;38(10):1409-1410
We observed 2 cases of occupational radiodermatitis which occurred during the radioisotope transpierce test. Patient 1, a 40-year-old man, noticed swelling, erythema, and stiffness on his left 2nd, 3rd, 4th, and 5th fingers 5 days after the exposure to about 2700 rem. Patient 2, a 32-year-old man, noticed painful swelling, erythema, bullae and necrosis on his right palm and thumb 1 week after the exposure to about 5500 rem. Clinicopathologically, patient 1 and 2 came under 2 and 3 burns respectively. The symptoms have been improving after treatment with systemic and topical corticosteroids and antibiotics.
Adrenal Cortex Hormones
;
Adult
;
Anti-Bacterial Agents
;
Burns
;
Erythema
;
Fingers
;
Humans
;
Necrosis
;
Radiodermatitis*
;
Thumb
8.Unexpected Multiple Organ Infarctions in a Poisoned Patient.
Sung Wook PARK ; Sang Kyoon HAN ; Seok Ran YEOM ; Soon Chang PARK ; Sung Hwa LEE
Korean Journal of Critical Care Medicine 2015;30(3):227-230
Predisposing factors for venous thrombosis can be identified in the majority of patients with established venous thromboembolism (VTE). However, an obvious precipitant may not be identified during the initial evaluation of such patients. In the present case, a 47-year-old female presented to the emergency department of our hospital after ingesting multiple drugs. She had no VTE-related risk factors or previous episodes, nor any family history of VTE. After admission to the intensive care unit sudden hypoxemia developed, and during the evaluation cerebral, renal, and splenic infarctions with pulmonary embolisms were diagnosed. However, the sources of the emboli could not be identified by transthoracic echocardiography or computed tomography angiography. Protein C deficiency was identified several days later. We recommend that hypercoagulable states be taken into consideration, especially when unexplained thromboembolic events develop in multiple or unusual venous sites.
Angiography
;
Anoxia
;
Causality
;
Echocardiography
;
Emergency Service, Hospital
;
Female
;
Humans
;
Infarction*
;
Intensive Care Units
;
Middle Aged
;
Protein C Deficiency
;
Pulmonary Embolism
;
Risk Factors
;
Splenic Infarction
;
Thrombophilia
;
Venous Thromboembolism
;
Venous Thrombosis
9.Acute Colchicine Poisoning Treated with Granulocyte Colony Stimulating Factor and Transfusion.
Sung Hwa LEE ; Sung Wook PARK ; Sang Kyoon HAN ; Soon Chang PARK
Korean Journal of Critical Care Medicine 2015;30(3):207-211
Colchicine poisoning is rare but can cause potentially life-threatening toxic complications such as hypovolemic shock, cardiovascular collapse and multiple organ failure. In this case report, we describe a case of a 20-year-old female who presented to the emergency department after suicidal ingestion of a toxic dose of colchicine. She developed thrombocytopenia, neutropenia and acute respiratory distress syndrome that required blood transfusion and administration of granulocyte colony stimulating factor for the prevention of infectious complications. With regard to the clinical manifestations of colchicine toxicity, we discussed suggested mechanisms.
Blood Transfusion
;
Colchicine*
;
Colony-Stimulating Factors*
;
Eating
;
Emergency Service, Hospital
;
Female
;
Granulocytes*
;
Humans
;
Multiple Organ Failure
;
Neutropenia
;
Poisoning*
;
Respiratory Distress Syndrome, Adult
;
Shock
;
Thrombocytopenia
;
Young Adult
10.Increased Expression of Caveolin-1 in Renal Cell Carcinoma.
Wook OK ; Eun Kyung BAE ; Sung Soo YOUN ; Kwang Sung AHN ; Han Yong CHO
Korean Journal of Urology 2000;41(5):602-608
No abstract available.
Carcinoma, Renal Cell*
;
Caveolin 1*