The hypertrophied prostate is the most common cause of infravesical obstrcutions, in the male patients with 50 years old or above. Though the cause of benign prostatic. hypertrophy has not clearly identified yet, recently it has been clarified that androgen, especially dihydrotestosterone, may play a great role in the benign prostatic hypertrophy. The author carried out to investigate the effect of Chlormadinone acetate-potent oral synthetic anti-androgen agent on prostatic volume and obstructive urinary symptoms induced by hypertrophied pro. static gland. The following results were obtained; 1. 23 patients were studied :19 patients with benign prostatic hypertrophy and 4 patients with benign prostatic hypertrophy and 4 patients with prostatic cancer. The mean age of patients was 72 years old. 2. The mean prostatic volume was markedly decreased from 58.7+/-2.94cc before treatment to 23.6+/-1.06cc 16 weeks after treatment. 3. Obstructive urinary symptoms, residual urine and nocturnal frequency were improved after treatment. 4. Judging from the fracts mentioned above, it may be believed that Chlormadinone acetate increase the effect of transurethral resection and prevent the rehypertrophied prostate after transurethral resection of prostate.
Aged ; Chlormadinone Acetate* ; Dihydrotestosterone ; Humans ; Hypertrophy ; Male ; Middle Aged ; Prostate ; Prostatic Hyperplasia ; Prostatic Neoplasms ; Transurethral Resection of Prostate

The vesicoureteral reflux is closely related to urinary tract infection in children and persistent vesicoureteral reflux with recurrent urinary tract infection is the common indication for antireflux plasty But it has been known that the vesicoureteral reflux was rare in Korea. From March 1979 to June 1984, author observed 13 patients with vesicoureteral reflux in the absence of any lower urinary tract obstruction, neuropathic disorder, inflammatory lesion at the base of the bladder, which were confirmed with IVP, VCUG and cystoscopy. The results were as follows 1. Age distribution was from 1 yr to 10 yr 2. Sex ratio of male to female was 1.1:1 3. Chief complaints at admission were fever 7 cases (53.9 %), flank pain 3 cases (23%), abdominal mass 2 cases (15.3%), incontinence 1 cases (7.6%). 4. Urinary culture at abmission revealed E. Coli in 9 patients (69%) and both E. Coli and Staphylococci in a patient. 5. 9 of 13 patients showed normal findings in IVP before treatment 6. 13 of 19 ureters showed one more than grade III in VCUG; before treatment. 7. In cystoscopy, shapes of 19 ureteral orifices with vesicoureteral reflux were golf-hole type 9 cases (47.4 %), horse-shoe type 2 cases (10.5 %), stadium type 1 case (5.2%), cone type 6 cases (31.6%) and in one case, it couldn`t be detected due to severe trabeculation. 8. Gregoir-Lich extravesical antireflux plasty were obtained in 13 of 19 ureters with vesicoureteral reflux without failure during four to seven follow-up months.
Age Distribution ; Child ; Cystoscopy ; Female ; Fever ; Flank Pain ; Follow-Up Studies ; Humans ; Korea ; Male ; Sex Ratio ; Ureter ; Urinary Bladder ; Urinary Tract ; Urinary Tract Infections ; Vesico-Ureteral Reflux*

Ninety-one cases of genitourinary tract injuries which were admitted to Severance Hospital during the period from Jan. 1960 to Aug. 1968 were analyzed clinically and statistically. And it was investigated compared with previous papers 1) The rate of genitourinary injuries accounted for 7.3 per cent to the total admission patients during eight years sixty-nine per cent of all injuries were in men and thirty-one per cent in women. The age distribution was much the same as that found in previous literature. Most favorable age was in from 20 to50 years for 72.5 percent 2) The meet common involvement site was in urethra for32.9 per cent while external genitalia showing most common site in war wound Also iatrogenic ureteral injuries was relatively high in spite of most less commonest incidence in previous paper 3) Thirty-six per cent of all injuries weredue to traffic or vehicular accident and twenty-four per cent 'due to iatrogenic. Majority of these iatrogenic injuries occurred in pelvic operation. Falls kick and blow were listed not less frequently. 4) On observation of kidney injuries. predisposed hydronephrotic kidney was injured more frequently due to mild external forces and three cases of sixteen kidney injuries had hydronephrosis dueto stone and congenital ureteral stricture in this series 5) An incidence of ureteral injury during radical hysterectomy was variable in literature. but it was noted around 10 percent generally. In reviewing 197 cases of radical hysterectomy for carcinoma of cervix, incidence of ureteral injuries was 12 cases(7.3 per cent) and it was listed 9.3 percent including bladder injuries. 6) In investigating bladder injuries, 53 percent of injuries were associated with pelvic bone fracture And 87 per cent was extraperitoneal type and 13 per cent wasin intraperitoneal rupture. 7) Also majority of urethral injuries were associatedwith pelvic bone fracture especially in car accident cases and then involved posterior urethra for 85 per cent. And bulbous urethra was injured by straddle injury for 70 per cent.
Age Distribution ; Cervix Uteri ; Constriction, Pathologic ; Female ; Genitalia ; Humans ; Hydronephrosis ; Hysterectomy ; Incidence ; Kidney ; Male ; Pelvic Bones ; Rupture ; Ureter ; Urethra ; Urinary Bladder ; Wounds and Injuries

A girl aged 18 years and 1 month, had a Angle's Class Iff malocclusion, characterized by anterior crossbite, anterior crowding, and constriction from right lower 2nd p emolar to right lower 2nd molar This ~i5 5s patient underwent scaling and 84148 extraction, and multibanded system was placed. After 14 months, anterior crossbite and crowding was corrected, andbothdental arches were improved. After 6 months from debanding, band space disappeared, and any relapse was not detected.
Constriction ; Crowding ; Female ; Humans ; Malocclusion* ; Molar ; Recurrence

No abstract available.
Life Style* ; Prostatism*

We studied 105 patients with trasmural myocardial infarction who were admitted to Soonchunhyang university hospital from 1984-1988, and evaluated the clinical and coronary angiographic findings accordin to the age. The following results were obtained: 1) Among 105 patients with myocardial infarction, the prevalent age were sixth and seventh decade(27.6%) and the ration of male to female was 2:1, But the raion of male to female was 5.3:1 under the 50 years of age. 2) In frequency of risk factor of coronarhy heart disease, cigarrette smoking was present in 66.7%, hypertensio in 44.8% and hypercholesterolemia in 28.6%. The mean number of risk factor was 1.3 under the 50 years of age and was 1.7 over the 50 years of age. 3) Anterior myocardial infarction was most common under 50 years of age whereas anterior and inferior myocardial infarction occur similarly over the 50 years of age. 4) By coronary angiography, one vessel disease of stenosis of left anterior descending coronary artery was common findings under 50 years of age, but multivessel disease was common findings over the 50 years of age.
Constriction, Pathologic ; Coronary Angiography ; Coronary Vessels ; Female ; Heart Diseases ; Humans ; Hypercholesterolemia ; Inferior Wall Myocardial Infarction ; Male ; Myocardial Infarction* ; Risk Factors ; Smoke ; Smoking

PURPOSE: This study focused on in vitro cell differentiation and surface characteristics in a magnesium coated titanium surface implanted on using a plasma ion source. MATERIALS AND METHODS: 40 commercially made pure titanium discs were prepared to produce Ti oxide machined surface (M) and Mg-incorporated Ti oxide machined surface (MM). Surface properties were analyzed using a scanning electron microscopy (SEM). On each surface, alkaline phosphatase (ALP) activity, alizarin red S staining for mineralization of MC3T3-E1 cells, and quantitative analysis of osteoblastic gene expression, were evaluated. Actin ring formation assay and gene expression analysis of TRAP and GAPDH performing RT-PCR were performed to characterize osteoclast differentiation on mouse bone marrow-derived macrophages (BMMs). RESULTS: MM showed similar surface morphology and surface roughness with M, but was slightly smoother after ion implantation at the micron scale. M was more hydrophobic than MM. No significant difference between surfaces on ALP activity at 7 and 14 days were observed. Real-time PCR analyses showed similar levels of mRNA expression of the osteoblast phenotype genes; osteopontin (OPN), osteocalcin (OCN), bone sialoprotein (BSP), and collagen 1 (Col 1) in cell grown on MM at 7, 14 and 21 days. Alizarin red S staining at 21 days showed no significant difference. BMMs differentiation increased in M and MM. Actin ring formation assay and gene expression analysis of TRAP showed osteoclast differentiation to be more active on MM. CONCLUSION: Both M and MM have a good effect on osteoblastic cell differentiation, but MM may speed the bone remodeling process by activating on osteoclast differentiation.
Actins ; Alkaline Phosphatase ; Animals ; Bone Remodeling ; Cell Differentiation ; Collagen ; Gene Expression ; Integrin-Binding Sialoprotein ; Macrophages ; Magnesium* ; Mice ; Microscopy, Electron, Scanning ; Osteoblasts* ; Osteocalcin ; Osteoclasts* ; Osteopontin ; Phenotype ; Plasma ; Real-Time Polymerase Chain Reaction ; RNA, Messenger ; Surface Properties ; Titanium*

The lower ureter is not so frequent site of the urinary tract obstruction. In lower ureteral obstruction, the obstruction should be relieved by any method for maintaining renal parenchyme. A clinical studies were made on the 24 ureters of the lower ureteral obstruction. This studies were mainly focused on the method of management by internal stent indwelling. The following results were obtained. 1. In etiology, acquired lower ureteral strictures were most common ; tuberculosis in 10 ureters, radiation in 6 ureters, pelvic lymphadenopathy in 4 ureters, and iatrogenic stricture in 3 ureters. Congenital UVJ stricture was only one ureter. 2. In the method of management, open surgeries were done in 10 ureters and endourologic methods in 14 ureters. 3. In 5 failures of the first management, open surgeries were done in 3 ureters and endourologic methods in 2ureters. The tuberculosis was the most of their etiology. 4. Complications in internal stent indwelled cases were flank pain, severe vesical irritation, migration into the bladder and the obstruction of the lumen of stent.
Constriction, Pathologic ; Flank Pain ; Lymphatic Diseases ; Stents* ; Tuberculosis ; Ureter* ; Ureteral Obstruction* ; Urinary Bladder ; Urinary Tract

In the surgical use of lasers in medicine, the laser light energy is transformed into heat within the tissue. As the result of this generation of heat, coagulation occurs and the tissue is carbonized and vaporized. The thermal effect depends upon the energy of the light radiation, its power and the irradiation time, the beam geometry, and the optical properties of the tissue itself, and also upon the thermal .parameters of the tissue such as its thermal conductivity and specific heat. In this experiment, to investigate the Neodymium-YAG laser effect on the bladder tissue and the extend of tissue damage at the various power and irradiation time under the same laser energy were aimed. Immediate after irradiation, the bladder tissues were fixed with formalin solution and H& E stained The extend of tissue damage was examined with light microscope. The following results were obtained: The effect of Neodymium-YAG laser irradiation on the bladder tissue was like a burn effect. Although the energy delivered to the tissue was the same, the resultant lesions created by the energy differed. The delivery of same energy in a low-power, long-duration manner made more tissue damage than a high-power, short-duration. Judging from the results of this experiment, it may be believed that a long period of irradiation time that there is sufficient time for the heat to be conducted into the surrounding tissue increases the zone of thermal damage and the coagulation necrosis.
Burns ; Carbon ; Formaldehyde ; Hot Temperature ; Lasers, Solid-State ; Necrosis ; Thermal Conductivity ; Urinary Bladder*

Takayasu's arteritis(arteritis syndrome) is an inflammatory disease process affecting primarily the aorta and its main branches. It's etiology and pathogenesis are unknown. Controversy exists in treatment. Segmental stenoses, occlusions, and aneurysmal degeneration of the aorta and the proximal arterial tree are frequent findings. Clinical presentations may include cerebrovascular ischemia, limb ischemia, aortic valvular insufficiency, heart failure, renovascular hypertension, or renal failure. Recently, we experienced a case of Takayasu's arteritis in a 24 years old female with severe dizziness, claudication in right upper extremity. Patient was treated by angioplasty of left vertebral artery and concomitant left subclavian-to-right axillary artery bypass surgery followed by percutaneous transluminal angioplasty with stent therapy of right vertebral artery to prevent cerebrovascular ischemia during the operation. Postoperative result was excellent and dizziness and claudication of right arm were completely relieved.
Aneurysm ; Angioplasty ; Aorta ; Arm ; Axillary Artery ; Constriction, Pathologic ; Dizziness ; Extremities ; Female ; Heart Failure ; Humans ; Hypertension, Renovascular ; Ischemia ; Renal Insufficiency ; Stents ; Takayasu Arteritis* ; Upper Extremity ; Vertebral Artery* ; Young Adult