1.Comparison of the E-test with agar dilution susceptibility test by using bacteroides fragilis.
Hee Sun KIM ; Sung Kwang KIM ; Hwa Sun CHA
Yeungnam University Journal of Medicine 1993;10(1):135-143
The susceptibilities of 45 clinical isolates of bacteroidis fragilis to cefaclor, ciproflxacin and imipenem were determined by new method, E-test (AB Bidisk, Solna, Sweden) and were compared with those from conventional agar dilution method by using brain heart infusion, Mueller-Hinton and Wilk:..s Chalgren agar plates. And the susceptibility of 60 clinical isolates of bacteroides fragilis group (B. fragilis 45 strains, B. distasonis 6 strains, B. ovatus 5 strains, B. thetaiotaomicron 4 strains) to 5 quinolones (ciprofloxacin, enoxacin, norfloxacin, ofloxacin, pefloxacin) were determined by in vitro agar dilution method. Compared with agar dilution MICs for B. fragilis 45 strains, 90.3% of E-test MICs were within +/- 1 dilution of the agar dilutions, and 98.4% were within 2 dilutions. And there were little effect of different medium bases to determine MICs except Mueller-Hinton agar. On Mueller-Hinton agar, B. fragilis showed have or no growth activity. In vitro susceptibility of B. fragilis group to quinolones, most of the test strains showed resistant patterns to quinolones except ofloxacin and there was little difference of susceptibility patterns between species of B. fragilis group.
Agar*
;
Bacteroides fragilis*
;
Bacteroides*
;
Brain
;
Cefaclor
;
Enoxacin
;
Heart
;
Imipenem
;
Norfloxacin
;
Ofloxacin
;
Quinolones
2.Effects of Hantaan Virus and IFN-gammaon Induction of Surface ICAM-1 in Primary Cultured Buman Nasal Epithelial Cells and Human Lung Fibroblasts.
Journal of the Korean Society of Virology 1998;28(4):317-325
The primary culture of human nasal epithelial cells was performed using the inferior nasal turbinate tissues, and infected with Hantaan virus to examine the hypothesis of airborne transmission of Hantaan virus in humans. The primary culture cells were identified as epithelial cells by morphologic and immunologic analyses. The viral antigens were detected in the primary human nasal epithelial cells infected with Hantaan virus by immunofluorescence staining. The ICAM-1 induction by Hantaan virus or IFN-gammawas examined in the primary human nasal epithelial cells and human lung fibroblasts (WI-38). Hantaan virus induced the surface ICAM-1 in Wl-38 cells in a time-dependent manner, and IFN-gammainduced the surface ICAM-1 in a dose-dependent manner in HNEC and WI-38 cells. These results revealed that the human nasal epithelial cells are susceptible to Hantaan viral infection supporting the hypothesis of airborne transmission of Hantaan virus in humans. The human lung fibroblasts also might have an important role in the pathogenesis of Hantaan virus through the induction of ICAM-1.
Antigens, Viral
;
Epithelial Cells*
;
Fibroblasts*
;
Fluorescent Antibody Technique
;
Hantaan virus*
;
Humans*
;
Intercellular Adhesion Molecule-1*
;
Lung*
;
Turbinates
3.Auditory brainstem response evoked by electrical stimulation (II): estimation of surviving spiral ganglion cells.
Myung Whun SUNG ; Chong Sun KIM
Korean Journal of Otolaryngology - Head and Neck Surgery 1991;34(6):1154-1159
No abstract available.
Electric Stimulation*
;
Evoked Potentials, Auditory, Brain Stem*
;
Spiral Ganglion*
4.Effects of anesthesia on the electrically-evoked middle latency responses on guinea pigs.
Korean Journal of Otolaryngology - Head and Neck Surgery 1993;36(4):601-611
No abstract available.
Anesthesia*
;
Animals
;
Guinea Pigs*
;
Guinea*
5.Hypohidrotic Ectodermal Dysplasia.
Sung Kyun KIM ; Hyoung Kyun KIM ; Sun Wook HWANG
Korean Journal of Dermatology 1980;18(5):471-477
A case of hypohidrotic ectodermal dysplasia was seen at the Dermatological Clinic of Chosun Univeraity Hospital, with a classical symptom triad consisting of hypohidrosis to anhidroais, hypotrichosis and hypodontia, and characteristic facial appearance. He was a 20 year-old male patient who presented, in addition, milium-like papules of sebaceous hyperplasia located on the nose and cheeks, supernumerary nipples of right breast, ceruminosis since childhood, and absence of apocrine glands on the axilla and pubic area, all of which are not frequently observed in hypohidrotic ectodermal dysplasia. Dermatoglyphics of this patient revealed that the axial triradius of the left palm was t, its atd angle was 42 degree, and the total ridge count of finger print was 5. This patient has no relatives showing the symptoms of hypohidrotic ectodermal dysplasia and the genetics was discussed in relation to this disease.
Anodontia
;
Apocrine Glands
;
Axilla
;
Breast
;
Cheek
;
Dermatoglyphics
;
Ectodermal Dysplasia 1, Anhidrotic*
;
Fingers
;
Genetics
;
Humans
;
Hyperplasia
;
Hypohidrosis
;
Hypotrichosis
;
Male
;
Nipples
;
Nose
;
Young Adult
6.Daily Topical Sequential Triple Therapy of Tretinoin, Betamethasone Valerate and Hydroquinone on Melasma.
Hyoung Kyun KIM ; Sung Kyun KIM ; Sun Wook HWANG
Korean Journal of Dermatology 1980;18(6):529-537
Daily topical sequential triple therapy(tretinoin, betamethasone valerate and hydroquinone), as proposed by Kligman et al and Gano et al, has been performed on 29 Korean female patients with melasma. After 4 weeks treatment with 2% hydroquinone cream, only three of eight patients (37. 5%) showed good to excellent results. However, after 4 weeks treatment with 4% hydroquinone cream, twelve of twentyone patients (57. 1%) showed good to excellent results and its therapeutic effects appeared more rapidly than the former group. Overall, after 4 weeks treatment. 96.6% of the total group showed fair to excellent results of which 57. 7% had a good to excellent rating. The fair-com- plexioned Koreans had a better response than dark-complexioned.
Betamethasone Valerate*
;
Betamethasone*
;
Female
;
Humans
;
Melanosis*
;
Tretinoin*
7.Effect of Lipopolysaccharide on the Expression of Chemokine Mig Gene in Mouse Peritoneal Macrophages.
Ho Suk DOH ; Sung Kwang KIM ; Hee Sun KIM
Journal of Bacteriology and Virology 2001;31(1):11-20
No abstract available.
Animals
;
Macrophages, Peritoneal*
;
Mice*
8.Transfer of Drugs Resistancy in Staphylococci.
Jae Kyu CHUNG ; Sung Kwang KIM ; Hee Sun KIM
Yeungnam University Journal of Medicine 1987;4(2):15-21
No abstract available.
9.Sugery and postoperative immunochemotherapy for theoracic esophageal cancer.
Kwang Taik KIM ; In Sung LEE ; Kyung SUN ; Hyoung Mook KIM
The Korean Journal of Thoracic and Cardiovascular Surgery 1993;26(3):214-218
No abstract available.
Esophageal Neoplasms*
10.Peridigital Dermatitis in Children.
Sun Wook HWANG ; Young Chang KIM ; Sung Kyun KIM
Korean Journal of Dermatology 1982;20(5):661-665
Papulonecrotic tuberculid (PNT) and Pityriasis lichenoides et varioliformis acuta (PLEVA) have been in controversy in their pathogeneses and entity itselves. Authors reviewed litera,tures of the two dermatoses with observation of nine casea of PNT from 1979 to 1981 and evaluated whether PNT could be also classified as PLEVA. The results were a,s follows: 1. By the review of literatures PNT and PLEVA showed great similarities in their clinical aspects including shape of cutaneous lesions, course, favorite age and subjecive symptoms. Histopathological overlappings were also found. 2. Of the nine cases of PNT authors observed, seven cases were histopathologically PLEVA and four cases could be thought PLEVA also clinically. But way six cases were treated by anti-tuberculous drugs. 3. The incidence of other tuberculous signs and results of tuberculin skin tests were all significant in the nine cases above. With the above observations it seems that PNT is one of the causes of PLEVA and thus could be a kind of PLEVA.
Child*
;
Dermatitis*
;
Humans
;
Incidence
;
Pityriasis Lichenoides
;
Skin Diseases
;
Skin Tests
;
Tuberculin
;
Tuberculosis, Cutaneous