2.Analysis of 200 Cases of Midtrimesteric Amniocentesis.
Jae Sung PARK ; Heun Ug JEON ; Sung Su KANG ; Hyun Woo CHUNG ; Yong Ho MOON ; Ki Sung CHUNG
Korean Journal of Obstetrics and Gynecology 1998;41(12):3044-3048
OBJECTIVE: We analyzed 200 cases of prenatal amniocentesis and compared them with other reported studies. Thus we propose the necessity of metanalysis for prenatal amniocentesis. METHOD: We analyzed 200 cases that have undergone amniocentesis at Masan Samsung hospital from January 1996 to December 1997. The results of our study was compared with other reported studies of amniocentesis by indication and maternal age. The proportion of age-class and indication are compared between previous study subjects and our 200 cases. RESULTS: Triple marker abnormality was the most common indication of amniocentesis(51%) and the most common age distribution was 25-29 years (43.5%). Chromosomal aberration was diagnosed in 20 cases (10%) of which the numerical aberration was 9 cases (4.5%) and the structural aberration was 11 cases (5.5%). 5 cases (2.5%) out of ll cases of the structural aberration were normal variant. There were 7 cases (trisomy 21) of autosomal aberration and 2 cases (Turner syndrome) of sex chromosome aberration. Arnong the structural aberration, there was only one reported case of 46, t(7:10) reciprocal translocation. There were no cases of fetal death except for a little self limited preterm labor. There were no neonatal complications. In the comparison of indication and maternal age with other studies, abnormal triple test was the most common indication of amniocentesis. The number of young pregnant women under 35 years old who underwent genetic amniocentesis was increased year by year. CONCLUSION: Triple maker screening test and genetic amniocentesis become popular method of antenatal diagnosis in Korea. Now, it is the proper time to establish standard indication of prenatal amniocentesis in this country by systemic and objective statistic examination. So we address the need for metanalysis in our country as comparing with other studies.
Adult
;
Age Distribution
;
Amniocentesis*
;
Chromosome Aberrations
;
Female
;
Fetal Death
;
Humans
;
Korea
;
Mass Screening
;
Maternal Age
;
Obstetric Labor, Premature
;
Pregnancy
;
Pregnancy Trimester, Second*
;
Pregnant Women
;
Prenatal Diagnosis
;
Sex Chromosome Aberrations
4.Clinical application of laparoscopy in gynecology.
Cheol Ho LEE ; Ann Su YI ; Kyoung Do PRK ; Hong Pil KIM ; Il Kyun CHUNG ; Ki Sung CHUNG
Korean Journal of Obstetrics and Gynecology 1993;36(7):1744-1752
No abstract available.
Gynecology*
;
Laparoscopy*
5.Studies on Bradycardiac Effect of Methoxamine in Rabbits.
Korean Journal of Anesthesiology 1987;20(3):341-348
The bradycardiac and presor to intravenous and intraventricular methoxamine were examined in urethane-anesthetized rabbits 1) Intravenous methoxamine produced bradycardiac pressor responses. Atropine (2 mg/kg, i,v.) weakened but not abloished the bradycardiac effect. 2) The bradycardiac effect elicited by intravenous methoxamine was not affected by int-ravenous prazosin, rehimbiine, guanethidine and propranolol, butt was attenuated by intra venous chlorisondamine reserpine. 3) The pressor effect elioited by intravenous methoxamine was weakened by prazosin, but was scarcely affected, rather potentiated, by intraTenous yohimblne, guanethidine, chlorisondamine, propranolol and resperpine. 4) Intraventricular methoxamine produced pressor and bradycardiac responses. 5) The bradycardiac effect elicited by intraventricular methoxamine was net affected by intravenous atropine, prasosin and yohimbine. This was attenuated by intravenous guane- thidine, chlorisondamine, propranolol and reserpine, and by intraventricular atropine prazosin and propranolol, respectively. 6) The pressor effect elicited by intraventricular methoxamine was attenuated by intra- ventricular and intravenous prazosin. This was not affected by intravenous atropine, gua-nethidine, chlorisondamine, propranolol, reserpine and yohimbine, and by intraventricular atropine, prasosin and Propranolol, respectivelr. 7) From these results it was inferred that bradycardiac effect elicited by methoxamine was not an action through the mediation of aleph 1-adrenoceptors but was a result from non-specific actions on some brain receptors.
Atropine
;
Brain
;
Chlorisondamine
;
Guanethidine
;
Methoxamine*
;
Negotiating
;
Prazosin
;
Propranolol
;
Rabbits*
;
Reserpine
;
Yohimbine
6.Clinical Studies on Congenital Heart Diseases.
Hee Young CHUN ; Dae Churl CHUNG ; In Kyung SUNG ; Kyong Su LEE ; Du Bong LEE
Journal of the Korean Pediatric Society 1990;33(1):66-74
No abstract available.
Heart Diseases*
;
Heart*
7.Changes in Blood Sugar , Insulin , Osmolarity and Electrolytes with Intraoperative Infusion of Various Solutions .
Chae Woon CHANG ; Jung Kil CHUNG
Korean Journal of Anesthesiology 1987;20(5):656-667
Rapid administration of solution containing dextroae results in marked hyperglycemia and osmotic diuresis hut a balanced electrolyte solution containing maltese does not increase blood sugar. 30 patients were chosen at random and divided into 3 groups j.e, one group received 5% dextrose in water, the second group received Hartmann solution and the third group, 5% maltose in a balanced electrolyte solution. The Patient's blood was collected in the operating room prior to the start l.V. infusion, for the measurement of blood sugar, insulin, osmolarity and electrolrtes in various conditions of N.P.O. Intravenous fluid was administered at a rate of 10 m1/kg/hour while anesthesia was induced and maintained with an endotracheal tube in place. Blood samples were taken one hour. 2 hours and 3 7ours f:on the time 1,V. infusion started, In the of 5% dextrose in water groups, the value of blood sugar and insulin was 88.5+/-12.1 mg% and 14.60+/-7.67 un/ml at NPO, 257.7+/-60.8mg% and 70.75+/-37.55 un/m1 at 1 hour, 298.8+/-84.4mg%: and 143.19+/-50.32 un/ml at 2 hours and 228.6+/-75.8% and 127.71+/-56.98 un/m1 at 3 hours. Although the b1ood sugar and insulin values increased markedly. but potassium and chloride were 4.74+/-0.55 mEq/l and 101.1+/-2.9 mEq/l and 4.11+/-0.31 mEq/l, 107.4+/-2.3 mEq/l and 3.75+/-0.41 mEq/l, 176.4+/-2.7mEq/l and 3.89+/-0.50mEq/l, 106.3+/-2.2 mEq/l and shoewed mild decrease, by the way, osmolarity and serum sodium did not changed. In contrast to the 5% dextrose in water groups, there are no changes in the blood glucose. insulin levels, osmolarity or and electrolrtes in the either Hartmann or Elitol (Elitol=5% maltose contained in a balanced electrolyte solution) groups. There was a slight increase in osmolarity with maltose but it was not significant. Accordingly it is concluded that rapid infusion of harmann or 5% maltose contained ina balanced electrolyte solution affects the blood sugar and insulin levels insignificantly compared to the dextrose cont5aining solution which increase the blood sugar and indulin levels markedly.
Anesthesia
;
Blood Glucose*
;
Diuresis
;
Electrolytes*
;
Glucose
;
Humans
;
Hyperglycemia
;
Insulin*
;
Maltose
;
Operating Rooms
;
Osmolar Concentration*
;
Potassium
;
Sodium
;
Water
8.Diaphragm Pacing: Phrenic Nerve Stimulation in Quadriplegia with Four-pole Electrode System.
Korean Journal of Anesthesiology 1993;26(4):810-819
Two patients with respiratory paralysis by cervical(C) injury were treated by sequential four-pole stimulation of the phrenic nerves to pace the diaphragm. With sequential four-pole nerve stimulator, full-time bilateral electroventi-lation were achieved and the conditioning of the diaphragm have been performed in 72 hours. According to other papers using unipolar or bipolar electrode, conditioning of the hypotrophic diaphragm took 2 to 1l months, and full-time electroventilation was possible in only about half of the patients, so part-time mechanical ventilation was needed in remained half of the patients. These results suggest that the conditioning time in patients with high quadriplegia could be significantly shortened and it should be possible to achieved independence from the mechani-cal ventilator when sequential four-pole stimulator was used.
Diaphragm*
;
Electrodes*
;
Humans
;
Phrenic Nerve*
;
Quadriplegia*
;
Respiration, Artificial
;
Respiratory Paralysis
;
Ventilators, Mechanical
9.Anesthetic Management for Thoraco-Xiphopagus Conjoined Twins: A case report.
Sang Do HAN ; Seong Hyun YANG ; Sung Su CHUNG ; Chang Young JEONG ; Chan Jin PARK
Korean Journal of Anesthesiology 1997;33(1):172-177
The incidence of conjoined twins is so rare that few anesthesiologists have an opportunity of managing them. Especially in Korea, there are only a few reports describing the anesthetic management for surgical separation of newborn conjoined twins. We experienced the successful anesthetic management for surgical separation of thoraco-xiphopagus conjoined twins without any particular problems. After applying the noninvasive monitors (ECG, pulse oximeter), one of the twins (twinA) with congenital heart disease was administered with intravenous ketamine for induction of anesthesia and intubated without neuromuscular blocker. Anesthesia was maintained with N2O-O2 and hand ventilation using Mapleson D breathing circuit. After maintaining airway of the twinA, the twinB was intubated and maintained with the same manner. Eighteen days after the separation procedure, the twinA with congenital heart disease died and the other one, twinB has been alive with normal growth and development.
Anesthesia
;
Growth and Development
;
Hand
;
Heart Defects, Congenital
;
Humans
;
Incidence
;
Infant, Newborn
;
Ketamine
;
Korea
;
Neuromuscular Blockade
;
Respiration
;
Twins, Conjoined*
;
Ventilation
10.The SEM Observation of The Various Root Treatment Effect On Furcation Area.
Hyun Su PARK ; Sung Bin LIM ; Chin Hyung CHUNG
The Journal of the Korean Academy of Periodontology 1997;27(1):205-215
In periodontal regeneration treatment, access to the frucation area is very difficult. Thus complete removal of plaque, calculus and endotoxin is somewhat impossible. In this study, teeth that were extracted due to periodontal disease were used. The furcation area was treated with periodontal curette, ultrasonic scaler, roto bur and they observed using SEM. The result was follows 1. The group treatment with curette showed remaining plaque, the cementum existed in most of the surface and partial dentinal tubule orifice could be seen. 2. The group treatment with ultrasonic scaler showed less removalof plaque compared to curette and irregular surface could be seen. 3. The group treatment with roto bur showed cleaner surface and many dentinal tubule orifice could be seen compared to the curette and ultrasonic scaler groups. Thus when suing treatments such as bone grafting or guided tissue regeneration, it is considered that the furcation area should be treatment with Roto bur.
Bone Transplantation
;
Calculi
;
Dental Cementum
;
Dentin
;
Guided Tissue Regeneration
;
Periodontal Diseases
;
Regeneration
;
Tooth
;
Ultrasonics