1.Anatomical measurements of the paranasal sinuses using PNS CT.
Hee Yoon KOO ; Kwang Ik KO ; Sung Su BAN ; Keum Suk KO ; Hee Wan PARK ; Kwang Ryun KO
Korean Journal of Otolaryngology - Head and Neck Surgery 1993;36(5):966-971
No abstract available.
Paranasal Sinuses*
2.Acute tubular necrosis as a part of vancomycin induced drug rash with eosinophilia and systemic symptoms syndrome with coincident postinfectious glomerulonephritis.
Kyung Min KIM ; Kyoung SUNG ; Hea Koung YANG ; Seong Heon KIM ; Hye Young KIM ; Gil Ho BAN ; Su Eun PARK ; Hyoung Doo LEE ; Su Young KIM
Korean Journal of Pediatrics 2016;59(3):145-148
Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome is a rare and potentially fatal condition characterized by skin rash, fever, eosinophilia, and multiorgan involvement. Various drugs may be associated with this syndrome including carbamazepine, allopurinol, and sulfasalazine. Renal involvement in DRESS syndrome most commonly presents as acute kidney injury due to interstitial nephritis. An 11-year-old boy was referred to the Children's Hospital of Pusan National University because of persistent fever, rash, abdominal distension, generalized edema, lymphadenopathy, and eosinophilia. He previously received vancomycin and ceftriaxone for 10 days at another hospital. He developed acute kidney injury with nephrotic range proteinuria and hypocomplementemia. A subsequent renal biopsy indicated the presence of acute tubular necrosis (ATN) and late exudative phase of postinfectious glomerulonephritis (PIGN). Systemic symptoms and renal function improved with corticosteroid therapy after the discontinuation of vancomycin. Here, we describe a biopsy-proven case of severe ATN that manifested as a part of vancomycin-induced DRESS syndrome with coincident PIGN. It is important for clinicians to be aware of this syndrome due to its severity and potentially fatal nature.
Acute Kidney Injury
;
Allopurinol
;
Biopsy
;
Busan
;
Carbamazepine
;
Ceftriaxone
;
Child
;
Drug Hypersensitivity Syndrome
;
Edema
;
Eosinophilia*
;
Exanthema*
;
Fever
;
Glomerulonephritis*
;
Humans
;
Kidney Tubular Necrosis, Acute
;
Lymphatic Diseases
;
Male
;
Necrosis*
;
Nephritis, Interstitial
;
Proteinuria
;
Sulfasalazine
;
Vancomycin*
3.Acute tubular necrosis as a part of vancomycin induced drug rash with eosinophilia and systemic symptoms syndrome with coincident postinfectious glomerulonephritis.
Kyung Min KIM ; Kyoung SUNG ; Hea Koung YANG ; Seong Heon KIM ; Hye Young KIM ; Gil Ho BAN ; Su Eun PARK ; Hyoung Doo LEE ; Su Young KIM
Korean Journal of Pediatrics 2016;59(3):145-148
Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome is a rare and potentially fatal condition characterized by skin rash, fever, eosinophilia, and multiorgan involvement. Various drugs may be associated with this syndrome including carbamazepine, allopurinol, and sulfasalazine. Renal involvement in DRESS syndrome most commonly presents as acute kidney injury due to interstitial nephritis. An 11-year-old boy was referred to the Children's Hospital of Pusan National University because of persistent fever, rash, abdominal distension, generalized edema, lymphadenopathy, and eosinophilia. He previously received vancomycin and ceftriaxone for 10 days at another hospital. He developed acute kidney injury with nephrotic range proteinuria and hypocomplementemia. A subsequent renal biopsy indicated the presence of acute tubular necrosis (ATN) and late exudative phase of postinfectious glomerulonephritis (PIGN). Systemic symptoms and renal function improved with corticosteroid therapy after the discontinuation of vancomycin. Here, we describe a biopsy-proven case of severe ATN that manifested as a part of vancomycin-induced DRESS syndrome with coincident PIGN. It is important for clinicians to be aware of this syndrome due to its severity and potentially fatal nature.
Acute Kidney Injury
;
Allopurinol
;
Biopsy
;
Busan
;
Carbamazepine
;
Ceftriaxone
;
Child
;
Drug Hypersensitivity Syndrome
;
Edema
;
Eosinophilia*
;
Exanthema*
;
Fever
;
Glomerulonephritis*
;
Humans
;
Kidney Tubular Necrosis, Acute
;
Lymphatic Diseases
;
Male
;
Necrosis*
;
Nephritis, Interstitial
;
Proteinuria
;
Sulfasalazine
;
Vancomycin*
4.A Case of Toxic Megacolon Caused by Clostridium difficile Infection and Treated with Fecal Microbiota Transplantation.
Tae Geun GWEON ; Kyung Jin LEE ; Donghoon KANG ; Sung Soo PARK ; Kyung Hoon KIM ; Hyeonjin SEONG ; Tae Hyun BAN ; Sung Jin MOON ; Jin Su KIM ; Sang Woo KIM
Gut and Liver 2015;9(2):247-250
Toxic megacolon is a rare clinical complication of fulminant Clostridium difficile infection. The mortality rate of fulminant C. difficile infection is reported to be as high as 50%. Fecal microbiota transplantation is a highly effective treatment in patients with recurrent or refractory C. difficile infection. However, there are few published articles on the use of such transplantation for fulminant C. difficile infection. Here, we report on a patient with toxic megacolon complicated by C. difficile infection who was treated successfully with fecal microbiota transplantation.
Aged
;
*Clostridium difficile
;
Enterocolitis, Pseudomembranous/*complications
;
Fecal Microbiota Transplantation/*methods
;
Feces/*microbiology
;
Humans
;
Male
;
Megacolon, Toxic/*microbiology/*therapy
5.Autosomal Dominant Polycystic Kidney Disease with an Asymptomatic Type I Choledochal Cyst.
Seung Jee RYU ; Kyung Hoon KIM ; Tae Wan KIM ; Woo Ho BAN ; Su Lim LEE ; Sung Soo KIM ; Young Ok KIM
Korean Journal of Medicine 2013;85(2):205-209
Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited renal disease. Polycystic liver disease is commonly observed in ADPKD but rarely has it been associated with a choledochal cyst. We report a case of a choledochal cyst with ADPKD in a 60-year-old female patient with ADPKD and concomitant chronic renal failure who was admitted because of acute deterioration of kidney function due to poor oral intake. There was no history of a biliary disorder and her kidney function recovered promptly after fluid replacement. Non-enhanced computed tomography was performed to evaluate ADPKD and revealed numerous cysts in both kidneys and liver. It also showed fusiform dilatation of the extrahepatic bile ducts, a finding indicative of a choledochal cyst. Liver function was within the normal range and there was no evidence of extrahepatic biliary obstruction. Magnetic resonance cholangiopancreatography confirmed the diagnosis of a type I choledochal cyst combined with ADPKD.
Bile Ducts, Extrahepatic
;
Cholangiopancreatography, Magnetic Resonance
;
Choledochal Cyst
;
Cysts
;
Dilatation
;
Female
;
Humans
;
Kidney
;
Kidney Failure, Chronic
;
Liver
;
Liver Diseases
;
Polycystic Kidney, Autosomal Dominant
;
Reference Values
6.Tracheal Bronchus with Persistent Pulmonary Hypertension of the Newborn: A Case Report.
Se Hwan AN ; Min Ju YI ; Rita YU ; Ji Hye KIM ; Hey Sung BAEK ; Ji Eun BAN ; Kyoung Ja LIM ; Seung YANG ; Il Tae HWANG ; Su Yeong KIM
Neonatal Medicine 2017;24(4):182-186
Tracheal bronchus is an uncommon anomaly in which an ectopic bronchus originates directly from the supracarinal trachea. It is usually an asymptomatic anatomical variant incidentally found on computed tomography or bronchoscopy. However, it can present with symptoms, such as chronic cough, wheezing, atelectasis, and recurrent pneumonia. We report a case of tracheal bronchus diagnosed in the neonatal period, in which the term baby presented with respiratory distress and persistent pulmonary hypertension of the newborn after birth, but no other congenital anomaly was found on further evaluation.
Bronchi*
;
Bronchoscopy
;
Cough
;
Female
;
Humans
;
Hypertension, Pulmonary*
;
Infant
;
Infant, Newborn*
;
Parturition
;
Persistent Fetal Circulation Syndrome
;
Pneumonia
;
Pulmonary Atelectasis
;
Respiratory Sounds
;
Trachea
7.Plasma C-Reactive Protein and Endothelin-1 Level in Patients with Chronic Obstructive Pulmonary Disease and Pulmonary Hypertension.
Yong Soo KWON ; Su Young CHI ; Hong Joon SHIN ; Eun Young KIM ; Byeong Kab YOON ; Hee Jung BAN ; In Jae OH ; Kyu Sik KIM ; Young Chul KIM ; Sung Chul LIM
Journal of Korean Medical Science 2010;25(10):1487-1491
Pulmonary hypertension is a frequent complication of chronic obstructive pulmonary disease (COPD) and associated with a worse survival and increased risk of hospitalization for exacerbation of COPD. However, little information exists regarding the potential role of systemic inflammation in pulmonary hypertension of COPD. The purpose of the present study was to investigate the degree of C-reactive protein (CRP) and endothelin-1 (ET-1) levels in COPD patient with and without pulmonary hypertension. The levels of CRP and ET-1 were investigated in 58 COPD patient with pulmonary hypertension and 50 patients without pulmonary hypertension. Pulmonary hypertension was defined as a systolic pulmonary artery pressure (Ppa) > or =35 mmHg assessed by Doppler echocardiography. Plasma CRP and ET-1 levels were significantly higher in patients with pulmonary hypertension than in patients without hypertension. There were significant positive correlations between the plasma ET-1 level and CRP level in the whole study groups. For COPD patients, systolic Ppa correlated significantly with plasma CRP levels and plasma ET-1 levels. These findings support a possibility that CRP and ET-1 correlate to pulmonary hypertension in COPD patients.
Aged
;
Blood Pressure
;
C-Reactive Protein/*analysis
;
Echocardiography, Doppler
;
Endothelin-1/*blood
;
Female
;
Humans
;
Hypertension, Pulmonary/*blood/complications
;
Male
;
Middle Aged
;
Pulmonary Disease, Chronic Obstructive/*blood/complications
8.Relationship between atopy and bronchial hyperresponsiveness to indirect stimuli in asthmatic children.
Tae Young PARK ; Min Ju YI ; Woo Hyeok CHOI ; Su Yeong KIM ; Rita YU ; Ji Eun BAN ; Seong YANG ; Il Tae HWANG ; Hey Sung BAEK
Allergy, Asthma & Respiratory Disease 2017;5(2):83-91
PURPOSE: Both atopy and bronchial hyperresponsiveness (BHR) are characteristic features of asthma. Several BHR studies comparing groups of atopic and nonatopic asthmatics have reported conflicting results. The aim of this study was to compare BHR to indirect stimuli, such as mannitol or exercise, between atopic and nonatopic asthmatics in children. METHODS: We performed a retrospective analysis of data from 110 children with asthma, aged 6–18 years using skin prick tests, and serum total and specific IgE levels. Atopy degree was measured using the sum of graded wheal size or the sum of the allergen-specific IgE. Bronchial provocation tests (BPTs) using methacholine were performed on all subjects. BPTs using indirect simuli, including exercise and mannitol, were also performed. RESULTS: Asthma cases were classified as atopic asthma (n=83) or nonatopic asthma (n=27) from skin prick or allergen-specific IgE test results. There was no significant difference in the prevalence of BHR to mannitol or exercise between atopic and nonatopic asthmatics. Atopic asthma had a significantly lower postexercise maximum decrease in % forced expiratory volume in 1 second (FEV1) (geometric mean [95% confidence interval]: 31.9 [22.9–40.9] vs. 14.0 [9.4–18.6], P=0.015) and a methacholine PC20 (provocative concentration of methacholine inducing a 20% fall in FEV1) than nonatopic asthmatics (geometric mean [95% confidence interval]: 1.24 [0.60–1.87] ng/mL vs. 4.97 [3.47–6.47]) ng/mL, P=0.001), whereas mannitol PD15 (cumulative provocative dose causing a 15% fall in FEV1) was not significantly different between the 2 groups. CONCLUSION: There was no significant difference in the prevalence of BHR to mannitol or exercise between atopic and nonatopic asthmatics in children.
Asthma
;
Bronchial Provocation Tests
;
Child*
;
Forced Expiratory Volume
;
Humans
;
Immunoglobulin E
;
Mannitol
;
Methacholine Chloride
;
Prevalence
;
Retrospective Studies
;
Skin
9.Serum periostin levels and squamous cell carcinoma-related antigen levels in children with atopic dermatitis.
Woo Hyeok CHOI ; Tae Young PARK ; Su Yeong KIM ; Rita YU ; Ji Eun BAN ; Seong YANG ; Il Tae HWANG ; Hey Sung BAEK
Allergy, Asthma & Respiratory Disease 2017;5(2):73-78
PURPOSE: It was found that periostin and squamous cell carcinoma-related antigens (SCCAs) were strongly interleukin-13-inducible gene products. This study measures the serum periostin and SCCA levels in children suffering from atopic dermatitis (AD) and to evaluate the association between the severity of AD and their values. METHODS: Seventy AD children aged 1 month to 10 years were included in our study. Subjects were characterized as having atopic eczema (AE; n=55) or non-AE (NAE; n=15) by atopic sensitization. Serum SCCA and periostin levels were measured. RESULTS: The serum periostin levels were significantly higher in children with AE than in those with NAE (geometric mean [95% confidence interval]: 80.47 ng/mL [75.06–85.93 ng/mL] vs. 67.45 ng/mL [59.99–75.64] ng/mL, P=0.020). The serum concentrations of both SCCA1 and SCCA2 were significantly higher in children with AE than in those with NAE (geometric mean [95% confidence interval]: 1.401 [1.198–1.643] ng/mL vs. 0.969 [0.723–1.268] ng/mL, P=0.039 for SCCA1) (1.178 [0.974–1.455] ng/mL vs. 0.711 [0.540–0.994] ng/mL, P=0.025 for SCCA2). The serum periostin levels were significantly correlated with disease severity and with peripheral blood eosinophil counts. The SCCA levels were not significantly correlated with disease severity. Both SCCA1 and SCCA2 were significantly correlated with serum periostin levels and blood eosinophil counts. CONCLUSION: Serum periostin levels may be significantly correlated with disease severity and blood eosinophil counts in children with AD. Serum SCCA levels can be significantly correlated with serum periostin levels and blood eosinophil counts in children with AD.
Child*
;
Dermatitis, Atopic*
;
Eosinophils
;
Epithelial Cells*
;
Humans
10.Clinical Characteristics of Secondary BPPV.
Jae Ho BAN ; No Hee LEE ; Hyun Jin CHOI ; Su Mi KIM ; Nam Hoon LEE ; Sung Jin LEE
Journal of the Korean Balance Society 2007;6(2):196-201
BACKGROUND AND OBJECTIVE: The purpose of this study was to identify clinical characteristics of secondary form of BPPV. MATERIALS AND METHODS:Of 384 patients with BPPV, 82 patients have a ipsilateral inner ear disease to the BPPV. We reviewed the site of lesion, duration of treatment in secondary BPPV and compared with idiopathic BPPV. RESULTS: The site of canal affected by idiopathic BPPV (M=119, F=183) showed that 138 (Lt=62, Rt=76) had a lateral canal, 157 (Lt=63, Rt=94) had a posterior canal, 7 had a multicanal. The involved canal by secondary BPPV (M=45, F=37) showed that 34 had a lateral canal, 43 in posterior canal, 1 in anterior canal and 4 in multicanal. 28 patients with idiopathic sudden sensory hearing loss developed BPPV within a few days (posterior=17, lateral=7, multicanal=4). 12 patients had a unilateral peripheral vestibulopathy and ipsilateral BPPV (posterior=11, lateral=1, anterior canal=1). 14 patients with meniere's disease developed ipsilateral BPPV (Lateral=9, posterior=5). 28 patients with BPPV had a history of headtrauma which is considered to be cause of BPPV. The mean duration of treatment is 2.68 on idiopathic BPPV, 6.27 on BPPV with ISSHL, 6.75 on BPPV with unilateral vestibulopathy, 2.28 on BPPV with meniere's disease and 2.4 on posttraumatic BPPV. There was no significant difference of recurrence among groups. CONCLUSION: Secondary BPPV showed different prevalence of involved canal from idiopathic BPPV. The duration of treatment for BPPV with ISSHL or unilateral vestibulopathy take longer time than for other groups.
Hearing Loss
;
Humans
;
Labyrinth Diseases
;
Meniere Disease
;
Prevalence
;
Recurrence
;
Vertigo