1.Retraction: Asp 280 residue is important in the activity of the Escherichia coli leader peptidase.
Mee Sook SUNG ; Kwang Sook PARK
Experimental & Molecular Medicine 1999;31(4):217-217
No abstract available.
3.The effect of cryopreservation to maintain long-term storage on canine trachea.
Sook Whan SUNG ; Seong Heo PARK
The Korean Journal of Thoracic and Cardiovascular Surgery 1991;24(5):438-444
No abstract available.
Cryopreservation*
;
Trachea*
4.Prenatal cytogenic study by midtrimester amniocentensis.
Sung Suk SEO ; Hae Ran HWANG ; Sung Sook JEON ; Chung Hee CHUN ; Sook Ja PARK
Korean Journal of Obstetrics and Gynecology 1993;36(9):3418-3425
No abstract available.
Female
;
Humans
;
Pregnancy
;
Pregnancy Trimester, Second*
5.Effect of ethanol feeding on production of IL-2 and IL-6, and otherparameters of immunocompatency in rats.
Tai You HA ; Byung Sook PARK ; Hee Sung HWANG
Korean Journal of Immunology 1991;13(1):17-31
No abstract available.
Animals
;
Ethanol*
;
Interleukin-2*
;
Interleukin-6*
;
Rats*
6.MR measurement of normal pituitary gland height on midsagittal section: age and sex differentiation.
Myung Soon KIM ; Jin Sook PARK ; Ki Joon SUNG
Journal of the Korean Radiological Society 1992;28(4):523-526
Measurement of the normal pituitary gland height was performed on magnetic resonance (MR) images of 144 subjects with no known or suspected pituitary or hypothalamic diseases. Midsagittal T1 weighted images (T1WI) were used for measurement, and mean vertical height according to age and sex group was obtained. In all age groups, the pituitary height was greater in females than in meles, The group of 0-9 years in both genders showed the minimum mean pituitary height, The maximum mean height was observed in the 10-19 years age group in both genders. The height gradually decreased with increasing age after age 20 years. There was no subject with a height more than 9.0 mm in females or 8.0 mm in males. In conclusion the measurement of the normal pituitary pland height using mid sagittal MR imaging can be used for the evaluation of the pituitary gland lesions.
Female
;
Humans
;
Hypothalamic Diseases
;
Magnetic Resonance Imaging
;
Male
;
Pituitary Gland*
;
Sex Differentiation*
7.Subendocardial Ischemic Necrosis in Hypertrophied Rabbit Heart Induced by Chronic Aoric.
Sung Sook KIM ; Dong Sun HAN ; Ie Tae PARK
Korean Circulation Journal 1997;27(7):738-743
BACKGROUND: Cardiac hypertrophy is the compensatory response of the myocadium to increased workload. Compensatory mechanisms come into play when the hypertrophied heart can no longer accommodate the increased demand or persistent stimuli. Although it has been reported that the molecular changes in hypertrophied hearts that initially mediate enhanced function may contribute to the development of heart failure, the structural/biochemical/molecular basis for myocardial contractile failure is still obscure. This study was aimed to clarify the structural basis for relation between hypertrophy and failure. METHOD: Nine pairs of rabbits were sacrificed at 8,12,24,48 hours and 1,2,4,6,8 weeks after experiment aortic constriction. There hearts were studied with routine histopathology. Each heart was weighed and compared with total body weight. Multiple sections were embedded in paraffin, sectioned at 5um, and stained with hematoxylin and cosin and Masson's trichrome and analysed. RESULTS: The heart weight to body weight ratio(g/Kg) increased progressively with time after aortic banding. Banding of the aorta in the rabbit resulted in multifocal areas of myofiber degeneration, necrosis and fibrosis through the wall of the left ventricle, in the papillary muscles of the left ventricle and in the left ventricular portions of the interventricular septum in rabbit of 6 and 8 weeks after aortic banding. By 4 weeks after banding, the foci of necrosis were not observed. CONCLUSION: There findings suggest that the increased necrosis, fibrosis in animals with cardiac hypertrophy induced by banding the aorta may play a role in progression to heart failure.
Animals
;
Aorta
;
Body Weight
;
Cardiomegaly
;
Constriction
;
Fibrosis
;
Heart Failure
;
Heart Ventricles
;
Heart*
;
Hematoxylin
;
Hypertrophy
;
Necrosis*
;
Papillary Muscles
;
Paraffin
;
Rabbits
8.Serodiagnosis of Syphilis.
Sook Ja SON ; Won Suk KIM ; Sung Ham PARK
Korean Journal of Dermatology 1975;13(4):271-279
The serodiagnostic test of syphilis employed with the greatest freguency in this country is the VDRL procedure which is one of the flocculation test utilizing cardiolipin-lecithin as an antigen. As well known, the immunologically nonspecific nature of this test relegates it only to screening test, so that all the sera displaying weakly reactive or reactive VDRL in the absence of definite evidence of present or past syphilis should be confirmed by using the specific treponemal antigen tests. However, there are only lirnited numbers of institutions at which the specific treponemal antigen tests are carried out, because the tests usually need quite coaiplicatnl technology and specifically trained personnel. The Treponema. pallidum hema.gglutination assay (TPHA) which was first described by Rathlev in 1965 and established as more improved and standardized procedure in serodia,gnosis of syphilis by Tornizaxva and Kasamatsu (1966) has been found to h as sensitive and specific as the technically more complicated Fluorescent treponemaI antibody absorption (FTA-ABS) or Treponema pallidum immobilization (TPI) po cedure by rnany investigators from different parts of the world during these 10 years. The TPHA has also been found to have definite advantage over the other tests because it is easy to perform and economic. The present authors felt. that the TPHA meight be the most reasonable method to be used in this country and decided to evaluate it in the serodiagnosis of problem cases. Sera from 516 presumed normal persons, 686 pregnant women ancl 1345 patients with various diseases other than syphilis were screened with the standard VDRL procedure as described and recommanded by USPHS. Out of these, 475 of t.he presumed normal persons, 646 of the pregnant women and 1243 of the patient group wit;h various diseases other than syphilis v;ere serologically nonreactive and 10, 12 and Rl sera from each of the above groups, respectively, were found to be true syphilitc with definite evidence of clinical signs or history of syphilis. Thirty-one out of the presumed normal persons, 28 out of the pregnant women and 71 out of the patient group with various diseases other than syphilis showed either weakly reactive or reactive VDRI, in undiluted sera without definite evidence of syphilis and these 130 sera from 130 persons were the subject of the present study. The TPHA was carried out on these 130 sera. according to the ma.nual MEA-TP instructed by National Institute of Health, Japan. The reagents used in this study rvere rnanufactured and supplied hy the Fujizoki Pharmaceutical Co. Ten (32.3%) out of the R1 sera from preaumed normal persons, 11 (39.4%) out of the 28 sera from pregna.nt women a.nd 28 (69.4%) out of the patient group with various disea ses other then syphilis showed reactive TPHA. Eighty-seven of the total 130 sera showed weakly reactive VDRL so called rough result and 19 (21.8%) Of these 87 sera showed reactive TPHA, while 30(69.8%) of the 43 sera which showed reactive VDRL were found to be TPHA reactive. These results arc in general agreement with those of other investigators confirmed by the more complicated FTA-ABS or TPI. The overall incidence of syphilis was 3.87%, 3.35% and 4.38% in presumed normal persons, in pregnant women and in patient group with various diseases other than syphilis respectively. Considering the relative lack of study concerning to the false positive reactions in this country, these results may be helpful to the clinician to rnake a cert.ain diagnostic decision when they meet such a patient whose VDRL is weakly reactive or reactive in the absence of definite evidence of syphilis. The authors concluded that: the MHA-TP technique is easy in performance, economic and highly specific in serodiagnosis and that this technique is highly recommanded in this country. * The authors thank Fujizoki Pharrnaceutical Company, Tokyo, Japan which provided the TPHA reagents used in this study.
Absorption
;
Bezafibrate
;
False Positive Reactions
;
Female
;
Flocculation Tests
;
Humans
;
Immobilization
;
Incidence
;
Indicators and Reagents
;
Japan
;
Mass Screening
;
Pregnant Women
;
Research Personnel
;
Serologic Tests*
;
Syphilis*
;
Treponema
;
Treponema pallidum
;
United States Public Health Service
9.Electron microscopic study on the response of the intestinal mucosa and macrophage to invasion of salmonella typhimurium.
Sung Sik PARK ; Sang Sook LEE ; Hyun Chul LEE
Korean Journal of Anatomy 1991;24(4):489-502
No abstract available.
Intestinal Mucosa*
;
Macrophages*
;
Salmonella typhimurium*
;
Salmonella*
10.Cytologic features of primary amelanotic melanoma of the vagina: a case report.
Sung Ran HONG ; Hy Sook KIM ; Chong Tack PARK
Korean Journal of Cytopathology 1993;4(1):41-44
No abstract available.
Melanoma, Amelanotic*
;
Vagina*