The concept of comfort has been regarded as a core concept of nursing and it has been frequently used as one of main goals of nursing care. Promoting comfort has been a very important objective in clinical nursing practice. There have been some ambiguities in defining the concept of 'comfort" among nursing scholars. Therefore it was necessary to analyse the concept of comfort for clearer definition to be able to share among scholars. This study is an attempt to analyse concept of comfort and to do it according to a series of concept development processes described by Walker and Avant. Based on the results of the study, the attributes of scope, precedence and consequence of comfort were identified : 1. Attributes 1) stability 2) directionality 3) equilibrium 4) firmness 2. Scope 1) physical 2) social 3) emotional 4) spiritua~ 3. Precedence and Consequence 1) precedence (1) instability (2) unsatisfied needs 2) consequence (1) physical & psychological relaxation (2) enhancement of self-worth (3) enhancement of self-efficacy (4) satisfied needs.
Nursing ; Nursing Care ; Relaxation

No abstract available.
Brain*

No abstract available.
Delivery of Health Care* ; Gyeongsangnam-do*

No abstract available.
Intercellular Adhesion Molecule-1* ; Prurigo*

No abstract available.
Bromodeoxyuridine* ; Cervix Uteri* ; Drug Therapy* ; Female

No abstract available.
Intestinal Mucosa* ; Macrophages* ; Salmonella typhimurium* ; Salmonella*

The aims of this study were to assess the role of p53 overexpression in colorectal tumorigenesis and the association with clinicopathological features. The immunohistochemical results were semiquantitatively assessed. Expression of aberrant p53, tumor-suppressor gene product, was studied immunohistochemically using a monoclonal antibody in 11 nonneoplastic polyps, 19 tubular adenomas, 9 villous adenomas, and 48 colorectal carcinomas. Five out of 11 nonneoplastic polyps, 14 out of 19 tubular adenomas and one out of 9 villous adenomas expressed p53 protein. Seven out of 24 colorectal carcinomas without lymph node metastasis and 14 out of 24 colorectal carcinomas with lymph node metastsis expressed p53 protein. The case of more than 75% positivity of p53 in colorectal carcinoma with lymph node metastasis was seven out of 24, but that in lymph node negative group was two out of 24. In the colorectal carcinoma with lymph node metastasis group; metastatic intranodal neoplastic cells were expressed positively for p53 in 10 out of 14 cases and zero out of 10 cases in group of positive and negative expression of primary lesions, respectively. p53 protein expression was not significantly correlated with variable clinicopathologic features such as age, sex, tumor location, tumor size, differentiation and Dukes' stage. It is suggested that p53 protein overexpression could be a early event in pathogenesis of colon cancer but is not involved in progression of villous adenoma to adenocarcinoma. p53 overexpression seems to be involved in metastatic ability of colorectal carcinomas.
Adenoma ; Neoplasm Metastasis ; Cell Transformation, Neoplastic

No abstract available.
Frontal Lobe* ; Neuropsychological Tests*

No abstract available.
Bipolar Disorder*

Tumor angiogenesis has been found to have prognostic significance in many tumor types for predicting an increased risk of metastasis. We assessed tumor vascularity in 28 cases of borderline malignancy and 71 cases of carcinoma of the ovary which had been resected and diagnosed, using the highly specific endothelial cell marker CD34. The numbers of microvessels were counted in 200 magnification in three highly vascularised areas. The numbers of microvessels in carcinomas were higher than that in the borderline malignancy of serous and mucinous tumors. The number of microvessels of mucinous carcinomas was significantly higher than that of serous carcinomas. There were neither significant differences in the number of microvessels according to histological tumor types (p=0.075) nor significant differences in the number of microvessels according to FIGO stages (p=0.072). But in serous carcinomas, the number of microvessels was higher in the FIGO III-IV stage than in the FIGO I-II stage (p=0.017). This study showed higher neovascularization in malignant tumor than borderline malignancy, and in the advanced stage (FIGO III-IV) than less advanced stage (FIGO I-II) of serous carcinomas.
Adenocarcinoma, Mucinous ; Endothelial Cells ; Female ; Microvessels ; Mucins ; Neoplasm Metastasis ; Ovary