The basis of surgical treatment of spondylolisthesis lies in the restoration of stability to the unstable spine and the decompression of the entrapped nerve root. Knodt's distraction rod has been thought to be one of effective distraction instruments promoting fusion for lumbar spine surgery. From December 1981 to May 1987, we performed surgical treatment of spondylolisthesis with Knodt's distraction rod instrumentation in 15 patients (Group I ) and fusion in situ in 7 patients (Group II ). Clinical analysis and changes of radiographic measurements of above two methods were evaluated and obtained following results. l. In Group I, the percentage slip and slip angle decreased to 12.1 ±6.3% and 0.2 ±6.6°, postoperatively, from 20.9 ±8.4% and 7.5 ±5.6°, respectively. In Group II, changed from 13.4 ±9.4%, 7.8 ±6.1°to 11.4 ±9.6%, 11.0 ±5.2°, respectively. 2. In Group I, the average reduction rate was 42.1% postoperatively, but decreased to 20.5% at follow-up. 3. The percentage posterior disc height increased to 49.0 ±6.7% postoperatively, from 27.4 ±10.0% in Group I and decreased to 34.7 ±5.3% at follow-up. But, in Group II, no significant changes observed. 4. The lumbar lordosis in Group I and Group II, decreased to 26.0 ±8.3°and 29.8 ±13.8°, postoperatively, from 35.5 ±7.8°and 37.6 ±1.4°, respectively. 5. There was no significant difference in clinical results between two groups. 6. Postoperstive complications in Group I, were one case of rod breakage with pseudarthrosis, 3 cases of voiding difficulty and superficial wound infection, in Group II, were 2 cases of superficial wound infection and 3 cases of transient voiding diffeculty.
Animals ; Decompression ; Follow-Up Studies ; Humans ; Lordosis ; Pseudarthrosis ; Spine ; Spondylolisthesis ; Wound Infection

The congenital absence of the extensor indicis proprius tendon was never reported but authors experienced one case of bilateral absence of the extensor indicis proprius tendon and treated by transfer of the extensor digiti quinti with good result.
Tendons

Frature of the tibial shaft is the most common fracture of the long bone and the treatment has become one of the most controversial subjects in orthopedic surgery. 61 cases of tibial shaft fracture in adults were treated by closed Kuntscher I-M nailing at the department of Orthopedic Surgery, Dae-Jeon Eul-Ji Hospital during 5 years from January, 1983 to December, 1987. In this paper we are reporting our result of 52 selected cases which we could follow up more than 6 months. The results were as follows. 1. The mean duration of clinical bone union was 9.6 weeks and that of radiological bone union was 15.6 weeks. 2. 6 cases of complication were noted with a little impairment of function finally. The complication were ankle joint stiffness(2), superficial infection(1), irritation of protruded nail(2) and bursting fracture(1). 3. Closed Kuntscher and occasionally combined interlocking I-M nailing are relatively short operative procedure with rigid fixation, low complication, wide indication and early weight bearing. So we consider them to be good methods of treatment for tibial shaft fractures.
Adult ; Ankle Joint ; Follow-Up Studies ; Humans ; Orthopedics ; Surgical Procedures, Operative ; Weight-Bearing

Avulsion of cervical nerve roots by traction injury to the shoulder girdle is well known, but, on the other hand, traumatic avulsion of lumbosacral nerve roots is exceedingly rare. The rarity of avulsion of lumbosacral nerve roots reflects the natural laxity of the roots and the strength and stability of the bony pelvis which offers support and protection to the nerve roots against stretching and rupture during trauma. We experienced a case of avulsion injury of L-S nerve roots associated with femoral shaft fracture. The myelography and C-T findings demonstrated multiple pseudomenigocele of dural sac at the level of the right L2, 3, 4, 5 and Sl S2 nerve roots.
Femur ; Hand ; Myelography ; Pelvis ; Rupture ; Shoulder ; Traction

No abstract available.
Humans ; Spinal Stenosis*

Radiation induced pemphigus, as an example of induced pemphigus, is a rare disease which occurs in patients receiving radiotherapy. A 56-year-old male patient with nasopharyngeal cancer received 3 cycles of chemotherapy and radiotherapy on the neck and anterior chest areas. One month after completion of radio-therapy, eroded and crusted areas developed within the irradiation site. In spite of systemic antibiotic treatment, the skin lesions persisted and spread further to the trunk and upper extremities with new crops of bullae. He was treated with a high dose of prednisolone and the skin lesions cleared. We discuss the suggestive pathogenesis of radiation-induced pemphigus with the comparative results of immunoblotting in various variants of pemphigus.
Cytochrome P-450 CYP1A1 ; Drug Therapy ; Humans ; Immunoblotting ; Male ; Middle Aged ; Nasopharyngeal Neoplasms ; Neck ; Pemphigus* ; Prednisolone ; Radiotherapy ; Rare Diseases ; Skin ; Thorax ; Upper Extremity

No abstract available.
Pulmonary Artery*

Median raphe cyst of the penis is an uncommon entity that usually presents as a cystic lesion on the ventral aspect of the penis, and which has a broad spectrum of histopathological appearances. It occurs most commonly near the glans penis, but may occur anywhere from the urethral meatus to the anus. It is solitary and measures only a few millimeters in diameter. Surgical excision is the treatment of choice. Recently we observed an 18-year-old male patient who had had a median raphe cyst since 5 years ago near the urethral orifice of the glans penis.
Adolescent ; Anal Canal ; Humans ; Male ; Penis*

PURPOSE: Hepatic allografts from donors with hepatitis B core antibody have been demonstrated to transmit hepatitis B virus (HBV) infection to recipients after liver transplantation (LT). The efficacy of hepatitis B immune globulin (HBIg) to prevent de novo hepatitis B was investigated by comparing active immunization in the early phase to HBIg monotherapy in the late phase of pediatric liver transplants at Samsung Medical Center. METHODS: Among pediatric liver transplants, from May, 1996 to June, 2002, 15 recipients who were hepatitis B surface antigen (HBsAg) (-) received an allograft from a donor with hepatitis B core antibody (HBcAb) (+). Except two who died from unrelated causes, eleven of 13 recipients were HBsAb (+), and 2 were naive (HBsAb(-), HBcAb(-)). All patients were vaccinated for HBV before LT. In the early phase (January, 1997~November, 1997, 3 patients), HBsAb (+) recipients received booster vaccination after LT. In the late phase (December, 1997~, 10 patients), all recipients were given booster vaccination and received HBIg therapy in order to maintain HBsAb titer greater than 200 IU/L. Lamivudine was given in one case because of severe side effect of HBIg. We retrospectively analyzed the effect of the preventive therapy for de novo hepatitis B through medical records. RESULTS: De novo hepatitis B developed in three of 13 recipients (23.1%). All of 3 patients who received active immunization in the early phase became HBsAg (+) at 7~19 months after transplantation. One of them was naive before LT and the other two were HBsAb (+). All of 10 recipients who were given HBIg in the late phase remained HBsAg (-) at 7~55 months' follow-up. CONCLUSION: Passive immunization with HBIg was effective for prevention of de novo hepatitis B in HBsAg (-) recipients of hepatic allografts from HBcAb (+) donors.
Allografts ; Follow-Up Studies ; Hepatitis B Surface Antigens ; Hepatitis B virus ; Hepatitis B* ; Hepatitis* ; Humans ; Immunization, Passive ; Lamivudine ; Liver Transplantation* ; Liver* ; Medical Records ; Retrospective Studies ; Tissue Donors ; Vaccination

AIMS AND METHOD: Comparative genomic hybridization serves as a screening test for regions of copy number changes in tumor genomes. I have applied the technique to map DNA losses and gains in 13 cases of frozen cholangiocarcinomas. RESULTS: All of the 13 cases showed genetic alterations. Loss of short arm of chromosome 19 (92%) was the most common changes observed. 22q(62%), 1p(54%), 17p(54%) and 19q(54%) also showed nonrandom patterns of genomic losses with high frequencies. Among the genomic gains, 13q was revealed as the most common site (69%), and 8q (46%) and 12q (46%) also showed relatively high frequencies of genomic gains. Genomic amplifications were detected on 5p13, 10q21.1 and 18q11.3 in 3 different cases, respectively. CONCLUSION: This study represents the first analysis of intrahepatic cholangiocarcinomas by CGH, and it confirms the presence of nonrandom genetic changes occur in the pathogenesis of cholangiocarcinomas. These findings should lead to the characterization of new loci involved in cholangiocarcinoma pathogenesis.
Arm ; Cholangiocarcinoma* ; Chromosome Aberrations* ; Chromosomes, Human, Pair 19 ; Comparative Genomic Hybridization* ; DNA ; Genome ; Mass Screening