1.Mammary Hamartoma: A case report.
Sung Ran HONG ; Hy Sook KIM ; Byung Jae CHO
Korean Journal of Pathology 1988;22(4):471-474
We have recently experienced a case of mammary hamartoma in 29-year-old woman. Hamartoma of the breast is a rare benign tumor-like lesion which is characteristically well demarcated by thin layer of fibrofatty tissue and composed of essentially normal mammary tissue with mammary glandular structure and fibrous stroma containing variable amounts of fat. The lobular architecture is relatively well preserved. It can be readily recognized, but should not be confused with fibroadenoma or mammary dysplasia. It also shows characteristic mammographic picture.
Female
;
Humans
;
Hamartoma
2.A case of congenital varicella.
Ran LEE ; Hyun Jung KOO ; Chung Sik CHUN ; Sung Hoon CHO
Korean Journal of Perinatology 1992;3(1):105-111
No abstract available.
Chickenpox*
3.Malignant Mesenchymoma of the Right Axillary Area: A case report.
Sung Ran HONG ; Gui Ohk YOON ; Seong Sook KIM ; Hye Jae CHO ; Il Hyang KO
Korean Journal of Pathology 1986;20(1):107-111
The term malignant mesenchymoma has been applied to those tumors of the soft tissue of mesenchymal origin which are composed of tumor cells differentiating into two or more unrelated malignant forms in addition to the fibrosarcomatous element. Recently authors experienced a case of malignant mesenchymoma in the right axillary area. Microscopically the sarcoma revealed multiple pattern of differentiation, including liposarcoma, malignant schwannoma, fibrosarcoma, malignant fibrous histiocytoma and rhabdomyoblastoma. The presence of rhabdomyblastic cells were proved by immunochemical study utilizing desmin. This patient was treated with surgical excision and radiation.
4.The effect of antenatal dexamethasone administration on the prevention of RDS in preterm delivery.
Jae Sung CHO ; Yoon Tae LEE ; Yong Won PARK ; Chan Ho SONG ; Ran NAMGUNG
Korean Journal of Obstetrics and Gynecology 1992;35(10):1483-1488
No abstract available.
Dexamethasone*
5.Red Blood Cell Transfusion in Autoimmune Hemolytic Anemia.
Youn Kyung KIL ; Young Jin CHOI ; Sung Ran CHO ; Hwi Jun KIM ; Hyun Ok KIM
Korean Journal of Clinical Pathology 1997;17(5):839-846
BACKGROUND: Autoimmune hemolytic anemias are characterized by autoantibodies recognizing antigens on the Individual's own red blood cells, resulting in immune- mediated hemolysis. Blood transfusions have been regarded as hazardous in patients with autoimmune hemolytic anemia (AIHA) because of potential intensification of hemolysis and a presumed high incidence of alloimmunization. METHODS: We examined the pretransfusion and posttransfusion hemoglobin levels in 6 patients with autoantibodies in their sera, which showed panagglutinations with all bloods tested in the compatibility testing. They received 'least' incompatible blood because of inability to find compatible blood. RESULTS: When we compared pretransfusion hemoglobin level with posttransfusion hemoglobin level, in 5 of 6 patients with AIHA, the hemoglobin levels were increased after red cell transfusion. 4 patient who did not respond to transfusion therapy initially had an increase in hemoglobin level after steroid treatment. Any signs or symptoms indicating hemolytic transfusion reaction were not observed ducting the transfusion period in all patients. CONCLUSIONS: The decision to transfuse in AIHA should consider multiple factors including the patient's clinical status, the potential benefit of transfusion, the potential response to other therapeutic modalities, but must never be regarded as contraindicated, even though the compatibility test may be strongly incompatible.
Anemia, Hemolytic*
;
Anemia, Hemolytic, Autoimmune
;
Autoantibodies
;
Blood Group Incompatibility
;
Blood Transfusion
;
Erythrocyte Transfusion*
;
Erythrocytes*
;
Hemolysis
;
Humans
;
Incidence
6.Red Blood Cell Transfusion in Autoimmune Hemolytic Anemia.
Youn Kyung KIL ; Young Jin CHOI ; Sung Ran CHO ; Hwi Jun KIM ; Hyun Ok KIM
Korean Journal of Clinical Pathology 1997;17(5):839-846
BACKGROUND: Autoimmune hemolytic anemias are characterized by autoantibodies recognizing antigens on the Individual's own red blood cells, resulting in immune- mediated hemolysis. Blood transfusions have been regarded as hazardous in patients with autoimmune hemolytic anemia (AIHA) because of potential intensification of hemolysis and a presumed high incidence of alloimmunization. METHODS: We examined the pretransfusion and posttransfusion hemoglobin levels in 6 patients with autoantibodies in their sera, which showed panagglutinations with all bloods tested in the compatibility testing. They received 'least' incompatible blood because of inability to find compatible blood. RESULTS: When we compared pretransfusion hemoglobin level with posttransfusion hemoglobin level, in 5 of 6 patients with AIHA, the hemoglobin levels were increased after red cell transfusion. 4 patient who did not respond to transfusion therapy initially had an increase in hemoglobin level after steroid treatment. Any signs or symptoms indicating hemolytic transfusion reaction were not observed ducting the transfusion period in all patients. CONCLUSIONS: The decision to transfuse in AIHA should consider multiple factors including the patient's clinical status, the potential benefit of transfusion, the potential response to other therapeutic modalities, but must never be regarded as contraindicated, even though the compatibility test may be strongly incompatible.
Anemia, Hemolytic*
;
Anemia, Hemolytic, Autoimmune
;
Autoantibodies
;
Blood Group Incompatibility
;
Blood Transfusion
;
Erythrocyte Transfusion*
;
Erythrocytes*
;
Hemolysis
;
Humans
;
Incidence
7.Two Cases of Transient Aplastic Crisis Associated with Human Parvovirus Bl9 Infection in Hereditary Spherocytosis and Hereditary Elliptocytosis.
Young Jin CHOI ; Youn Kyung KIL ; Sung Ran CHO ; Hwi Jun KIM ; Seung Ho BAICK
Korean Journal of Clinical Pathology 1997;17(5):694-702
Among the causes of pure red cell aplasia, human parvovirus B19 has been shown to be cytotoxic to erythroid progenitor cells in the bone marrow associated with chronic hemolytic anemia with rapidly dividing erythroids and persistently to be suppression of erythropoiesis in immunocompromised individuals related with failure to produce neutralizing antibody to the virus. In a patient with hereditary spherocytosis presenting acute onset of reticulocytopenia during hospitalization, who had shown severe anemia and prodromal symptoms including fever, fatigue and dizziness, infection of parvovirus Bl9 was proven by the presence of IgM and IgG antibodies to parvovirus Bl9, the detection of viral DNA using PCR technique in her serum and the decreased erythroid cells, especially late normoblasts in bone marrow, Also in the other who was diagnosed as hereditary elliptocytosis and complained of fever, headache, abdominal pain and diarrhea, an episode of reticulocytopenia and the nearly absence of late normoblasts in the bone marrow were observed. IgM antibodies to parvovirus Bl9 and the viral DNA were detected in her serum, too.
Abdominal Pain
;
Anemia
;
Anemia, Hemolytic
;
Antibodies
;
Antibodies, Neutralizing
;
Bone Marrow
;
Diarrhea
;
Dizziness
;
DNA, Viral
;
Elliptocytosis, Hereditary*
;
Erythroblasts
;
Erythroid Cells
;
Erythroid Precursor Cells
;
Erythropoiesis
;
Fatigue
;
Fever
;
Headache
;
Hospitalization
;
Humans*
;
Immunoglobulin G
;
Immunoglobulin M
;
Parvovirus B19, Human
;
Parvovirus*
;
Polymerase Chain Reaction
;
Prodromal Symptoms
;
Red-Cell Aplasia, Pure
8.Two Cases of Transient Aplastic Crisis Associated with Human Parvovirus Bl9 Infection in Hereditary Spherocytosis and Hereditary Elliptocytosis.
Young Jin CHOI ; Youn Kyung KIL ; Sung Ran CHO ; Hwi Jun KIM ; Seung Ho BAICK
Korean Journal of Clinical Pathology 1997;17(5):694-702
Among the causes of pure red cell aplasia, human parvovirus B19 has been shown to be cytotoxic to erythroid progenitor cells in the bone marrow associated with chronic hemolytic anemia with rapidly dividing erythroids and persistently to be suppression of erythropoiesis in immunocompromised individuals related with failure to produce neutralizing antibody to the virus. In a patient with hereditary spherocytosis presenting acute onset of reticulocytopenia during hospitalization, who had shown severe anemia and prodromal symptoms including fever, fatigue and dizziness, infection of parvovirus Bl9 was proven by the presence of IgM and IgG antibodies to parvovirus Bl9, the detection of viral DNA using PCR technique in her serum and the decreased erythroid cells, especially late normoblasts in bone marrow, Also in the other who was diagnosed as hereditary elliptocytosis and complained of fever, headache, abdominal pain and diarrhea, an episode of reticulocytopenia and the nearly absence of late normoblasts in the bone marrow were observed. IgM antibodies to parvovirus Bl9 and the viral DNA were detected in her serum, too.
Abdominal Pain
;
Anemia
;
Anemia, Hemolytic
;
Antibodies
;
Antibodies, Neutralizing
;
Bone Marrow
;
Diarrhea
;
Dizziness
;
DNA, Viral
;
Elliptocytosis, Hereditary*
;
Erythroblasts
;
Erythroid Cells
;
Erythroid Precursor Cells
;
Erythropoiesis
;
Fatigue
;
Fever
;
Headache
;
Hospitalization
;
Humans*
;
Immunoglobulin G
;
Immunoglobulin M
;
Parvovirus B19, Human
;
Parvovirus*
;
Polymerase Chain Reaction
;
Prodromal Symptoms
;
Red-Cell Aplasia, Pure
9.Two Cases of Neonatal Osteomyelitis due to Extended Spectrum beta-lactamase Producing Klebsiella pneumoniae.
Hye Kyung LEE ; Sung Ran CHO ; Soon Lee JUNG
Journal of the Korean Society of Neonatology 1998;5(2):237-241
The most common etiologic agents of neonatal osteomyelitis in the last decades were Staphylococcus aureus, Group B streptococcus, and E. coli, but Klebsiella pneumoniae as a cause of neonatal osteomyelitis appears to be rare. Klebsiella pneumoniae is one of the most important organisms associated with hospital acquired infections in the neonate and outbreaks with multiresistant strains have been reported from neonatal intensive care units around the world. These multiresistant Klebsiella pneumoniae have been shown to produce tranferable plasmid mediated beta-lactamases that are able to hydrolyze oxyimmino- beta-lactamas and these confer resistance to the third generation cephalosporin and named extended spectrum beta-lactamase producing Klebsiella pneumoniae. We experienced two cases of neonatal osteomyelitis due to extended spectrum lactamase producing Klebsiella pneumoniae in our neonatal intensive care unit during the same period. To our knowledge this represents the first documented neonatal osteomyelitise to extended spectrum beta-lactamase producing Klebsiellae pneumoniae in Korea.
beta-Lactamases*
;
Disease Outbreaks
;
Humans
;
Infant, Newborn
;
Intensive Care Units, Neonatal
;
Intensive Care, Neonatal
;
Klebsiella pneumoniae*
;
Klebsiella*
;
Korea
;
Osteomyelitis*
;
Plasmids
;
Pneumonia
;
Staphylococcus aureus
;
Streptococcus
10.Plasma cell leukemia with rouleaux formation involving neoplastic cells and RBC.
Korean Journal of Hematology 2011;46(3):152-152
No abstract available.
Leukemia, Plasma Cell
;
Plasma
;
Plasma Cells