1.Magnesium vs. machined surfaced titanium - osteoblast and osteoclast differentiation.
Yong Dae KWON ; Deok Won LEE ; Sung Ok HONG
The Journal of Advanced Prosthodontics 2014;6(3):157-164
PURPOSE: This study focused on in vitro cell differentiation and surface characteristics in a magnesium coated titanium surface implanted on using a plasma ion source. MATERIALS AND METHODS: 40 commercially made pure titanium discs were prepared to produce Ti oxide machined surface (M) and Mg-incorporated Ti oxide machined surface (MM). Surface properties were analyzed using a scanning electron microscopy (SEM). On each surface, alkaline phosphatase (ALP) activity, alizarin red S staining for mineralization of MC3T3-E1 cells, and quantitative analysis of osteoblastic gene expression, were evaluated. Actin ring formation assay and gene expression analysis of TRAP and GAPDH performing RT-PCR were performed to characterize osteoclast differentiation on mouse bone marrow-derived macrophages (BMMs). RESULTS: MM showed similar surface morphology and surface roughness with M, but was slightly smoother after ion implantation at the micron scale. M was more hydrophobic than MM. No significant difference between surfaces on ALP activity at 7 and 14 days were observed. Real-time PCR analyses showed similar levels of mRNA expression of the osteoblast phenotype genes; osteopontin (OPN), osteocalcin (OCN), bone sialoprotein (BSP), and collagen 1 (Col 1) in cell grown on MM at 7, 14 and 21 days. Alizarin red S staining at 21 days showed no significant difference. BMMs differentiation increased in M and MM. Actin ring formation assay and gene expression analysis of TRAP showed osteoclast differentiation to be more active on MM. CONCLUSION: Both M and MM have a good effect on osteoblastic cell differentiation, but MM may speed the bone remodeling process by activating on osteoclast differentiation.
Actins
;
Alkaline Phosphatase
;
Animals
;
Bone Remodeling
;
Cell Differentiation
;
Collagen
;
Gene Expression
;
Integrin-Binding Sialoprotein
;
Macrophages
;
Magnesium*
;
Mice
;
Microscopy, Electron, Scanning
;
Osteoblasts*
;
Osteocalcin
;
Osteoclasts*
;
Osteopontin
;
Phenotype
;
Plasma
;
Real-Time Polymerase Chain Reaction
;
RNA, Messenger
;
Surface Properties
;
Titanium*
2.Coping with Experiences in Multiple Chronic Diseases in the Rural Elderly.
Eun Ok JOUNG ; Sung Bok KWON ; Ok Hee AHN
Journal of Korean Academy of Community Health Nursing 2007;18(1):32-41
PURPOSE: The purpose of this study was to describe how the rural elderly cope with experiences in multiple chronic diseases. METHOD: Data were collected through participant observation and in-depth interview using ethnography. The participants were 9 women and 2 men who aged over 65, were living in rural community, and had experienced two or more chronic diseases. RESULTS: According to the results of this study, those who had experienced multiple chronic diseases went through the stages of 'recognizing of revealed symptoms', 'discovering of disease', 'overcoming', 'neglecting', 'discovering another disease', 'being frustrated' and 'living with suffering'. CONCLUSION: The results of this study are expected to be utilized as basic materials to develop a nursing intervention program for effective management of chronic diseases.
Aged*
;
Anthropology, Cultural
;
Chronic Disease*
;
Female
;
Humans
;
Male
;
Nursing
;
Rural Population
3.The dental arch form in normal occlusion.
Yong Chul KWON ; Jung Ok SUNG ; Oh Won KWON ; Jae Hvun SUNG
Korean Journal of Orthodontics 1989;19(1):95-106
This study was designed to investigate dental arch shapes buccally and lingually at Bracket Level of Koreans. This involved studying 63 inviduals (37 males, 26 females) with normal occlusion ranging in age from 17 to 24 years old. The landmarks were digitized and measurements and statistical analysis were performed by NEC 9801 V-M computer. The Results were as Follows: Bicanine width, Bipremolar width and Bimolar width were larger in males than in females. Buccal and lingual arch form and coordination form were obtained by NEC 9801 V-M computer. The parabolic equations which represents buccal and lingual arch form were obtained.
Dental Arch*
;
Female
;
Humans
;
Male
;
Young Adult
4.Living as Severe COPD Patient: Life of Stepping on the Thin Ice.
Sung Reul KIM ; Yun Ok KIM ; Kyoung Min KWON
Journal of Korean Academy of Adult Nursing 2010;22(6):663-675
PURPOSE: The purpose of this study was to explore the life experiences of patients with a severe Chronic Obstructive Pulmonary Disease (COPD). METHODS: The data were collected through in-depth interviews of six patients suffering from severe COPD. The interviewed data were audio-recorded and transcribed verbatim and checked for accuracy. The Giorgi method of phenomenology was used for analyzing data. RESULTS: Eight themes forming the, units of meaning, were: Repeated and Unpredictable Suffering of Dyspnea, Confidence Loss/Exhaustion Life due to non-efficient breathing, Gradually Deprived Liberty, Absolute Being to Sustaining my life, Source of Burden but Significant Person I am in the Family, Endless Tug-of-War-Capability/Endeavor to Breath, Longing for my Life, and Dead-end of breathing. CONCLUSION: The study results provide an in-depth understanding of life experiences of patients suffering from severe COPD. The findings will be useful to nurses caring for this population.
Dyspnea
;
Freedom
;
Humans
;
Ice
;
Life Change Events
;
Pulmonary Disease, Chronic Obstructive
;
Respiration
;
Stress, Psychological
5.Evaluation of pneumoreduction in intussusception with sign of frank intestinal obstruction.
Dong Heon OH ; Ok Hwa KIM ; Ki Sung KIM ; Yong Kil KIM ; Jung Hyeok KWON
Journal of the Korean Radiological Society 1993;29(3):553-560
Intussusception is the most common cause of acquired intestinal obstructions during infancy and early childhood. Barium reduction and pneumoreduction have been sued widely as nonsugical method of treatment in radiologic department. In the past, attempts at barium reduction of intussusception were contraindicated in the presence of frank intestinal obstruction, shock, fever, dehydration, bowel perforation, peritonitis and longstanding symptoms. At present, however, there is no agreement on the contraindications, except for shock, peritonitis and bowel perforation. Especially, there is no consensus regarding its application on patient presenting with sign of frank intestinal obstruction. The authors analyzed the effect of pneumoreduction in the intussusception with sign of frank intestinal obstruction. Pneumoreduction was attempted in 53 cases of intussusception with sign of frank intestinal obstruction. Reduction was successful in 43 cases(81%). The mean fluroscopic time was 15.1 minutes and mean maximal pressure was 121.8mmHg in successful reduction. As complications, two cases of bowel perforation were observed, but could be treated surgically without any significant problem. In conclusion, pneumoreduction is a useful substitute for barium reduction in the management of pediatric intussusception with sign of frank intestinal obstruction.
Barium
;
Consensus
;
Dehydration
;
Fever
;
Humans
;
Intestinal Obstruction*
;
Intussusception*
;
Methods
;
Peritonitis
;
Shock
6.Chest radiographic findings of scrub typhus: An analysis of 160 cases occurred in Ulsan area.
Ok Hwa KIM ; Dong Heon OH ; Ki Sung KIM ; Je Ho WOO ; Jung Hyeok KWON
Journal of the Korean Radiological Society 1993;29(2):205-210
Scrub typhus (Tsutsugamushi disease)is an acute febrile systemic illness caused by Rickettsia tsutsugamushi that is transmitted to humans by the bite of larval-stage trombiculid mites (chiggers). The authors analyzed chest radiographic findings of scrub typhus in 160 patients in Ulsan area. One hundred and eight (67.5%) of160 patients showed abnormal findings which included lung lesions in 108 patients (67.5%), cardiomegaly in 37 patients (23.1%), lymphadenopathy in 25 patients (15.6%) and pleural effusion in 11 patients (6.9%). Among the lung lesions, interstitial patterns were seen in 107 patients (66.9%), mostly fine or medium reticulonodular, and air-space patterns in 14 patients(8.8%) and combined interstitial and air-space patterns in 13 patients (8.1%). Sixty-four patients(40%) had combined chest radiographic findings. The typical chest radiographic findings of scrub typhus would be helpful in evaluation of the causes of acute febrile illness that occur during late fall in the endemic area.
Cardiomegaly
;
Humans
;
Lung
;
Lymphatic Diseases
;
Orientia tsutsugamushi
;
Pleural Effusion
;
Radiography, Thoracic*
;
Scrub Typhus*
;
Thorax*
;
Trombiculidae
;
Ulsan*
7.A clinical study on painless delivery.
Sung Don KIM ; Hyun Ok KWON ; Il HONG ; Se Hwan KIM ; In Chul SONG
Korean Journal of Obstetrics and Gynecology 1993;36(6):764-772
No abstract available.
8.Analyses on the Factors Related to Stages of Dietary Behavioral Changes among Child Bearing Aged Women.
The Korean Journal of Nutrition 2003;36(7):759-768
This study examined the factors related to stages of dietary behavioral changes among 1449 child bearing aged women (mean age +/- SD = 25.6 +/- 5.3 years) residing in large cities. A self administered questionnaire was used to assess stages of dietary behavioral change, meal balance and regularity, food availability, nutrition knowledge, body mass index, nutrient intake, and psycho-social factors including self efficacy, perceived benefits and barriers, social modeling. Undesirable dietary behaviors (precontemplation and contemplation) were shown among 45.1-57.4% of the participants, among those, 33.4-43.0% were precontemplators. Participants'' self efficacy scores associated with dietary changes were higher in specific situations (3.42) as compared to general situations (2.86). Similarly, they appeared to perceive more benefits (3.86) rather than barriers (2.76) by changing their inappropriate eating habits. Perception and accuracy scores of nutrition knowledge were relatively high, indicating 90.9 and 80.1, respectively. In terms of food availability at home, fresh fruits received the highest score, followed by milk and milk products, vegetables, meat, alcoholic beverages and soft drinks. In social modeling assessment, family members, as compared to friends, appeared to have better dietary habits. Stages of dietary behavioral change assessed in terms of meal regularity were associated with nutrient intake, showing higher energy and carbohydrate intakes but lower fat intake among those who belonged to the action and maintenance stage. They also presented higher self efficacy and perceived more benefits and less barriers regarding the change of undesirable eating habits. Fresh meat and vegetables were more available among those maintaining desirable dietary habits. Results of this study presented the significant relations of motivational and reinforcing social factors with stages of dietary behavioral changes and a need for the development of tailored nutrition education program considering these factors for child-bearing aged Korean women.
Alcoholic Beverages
;
Body Mass Index
;
Carbonated Beverages
;
Child*
;
Eating
;
Education
;
Female
;
Food Habits
;
Friends
;
Fruit
;
Humans
;
Meals
;
Meat
;
Milk
;
Surveys and Questionnaires
;
Self Efficacy
;
Vegetables
9.Therapeutic Endoscopic Retrograde Cholangiography in Patients with a Billroth II Gastrectomy: 2 cases of ERBD & 1 case of endoscopic stone retrievial.
Dong Ki LEE ; Sung Woo LEE ; Sung Rul KIM ; Sun Woo BAE ; Woo Ick JANG ; Sang Ok KWON
Korean Journal of Gastrointestinal Endoscopy 1992;12(2):271-277
Endoscopic retrograde cholangiopancreatography(ERCP) procedures are more difficult in patients who have undergone partial gastrectomy with Billroth II anastomosis. Because its altered anatomical relationship. the endoscopist is presented with additional problems: (i) Dfficulties in entering the afferent loop, depending on the surgical techiques used. (ii) The endoscope may be too sort to reach the papillary region unless the loops are suecessfully straightened out. (iii) Difficulties in passing the ligament of Treitz, especially in patients with Braun's anastomosis, (iv) Problems in cannulating the papilla and especially the common bile duct from a reversed position. (v) Problems in carrying out a papillotomy in a correct position. We attempted endoscopic sphincterotomy in 3 opatients previously subjected to gastrectomy with needle knife, and succeeded in 2 of them. In the two patients, successful billary drainage was achieved. And one patients with Billroth II gastrectomy, presented with CBD stone and cholangit, was successfully treated with endoscopic stone retriveial. The patient with a Billroth-II operation may unergo endscopic diagnostic as well as therapeutic procedures with a high rate of success, and can be suitable candidates for ERCP and endoscopic sphincterotomy
Cholangiography*
;
Cholangiopancreatography, Endoscopic Retrograde
;
Common Bile Duct
;
Drainage
;
Endoscopes
;
Gastrectomy*
;
Gastroenterostomy*
;
Humans
;
Ligaments
;
Needles
;
Sphincterotomy, Endoscopic
10.Cephalometric norms for orthognathic surgery.
Jung Ok SUNG ; Hee Moon KYUNG ; Oh Won KWON ; Jae Hyun SUNG
Korean Journal of Orthodontics 1989;19(1):169-185
The purpose of this study was to establish Korean norms that will be valuable aids for diagnosis in orthognathic surgery patients. Lateral cephalometric measurements were established for adult Koreans (60 males, 62 females) with normal occlusion and acceptable profiles. The results were as follows: 1. Means, standard deviation and sexual differentiation were included within each measurement. 2. In skeletal measurements, FH to SN and SN to mandibular plane measurements in females were larger than those in males while all linear measurements in males were larger than those in males were larger than those in females. 3. Significant differences were observed between male and female groups on all of the items that showed vertical relationship in dental measurements. And the measurements of ADH, PDH and overbite in males were larger than those in females while the measurements of incisor exposure in females were larger than those in males. 4. In all measurements of soft tissue except NLA, that is, of FCA, UFH, ULL and LLL, males were larger than those in females.
Adult
;
Diagnosis
;
Female
;
Humans
;
Incisor
;
Male
;
Orthognathic Surgery*
;
Overbite
;
Sex Differentiation