Radical prostatectomy, external irradiation, and brachytherapy are currently available for the cure of early localized prostatic cancer. This report documents the first successful Iodine-125 seeds implant treatment of early prostatic cancer in Korea. Patient was 70-year-old man with mild urinary urgency and nocturia. Serum PSA (prostate specific antigen) was 6.51ng/ml. Transrectal ultrasonography showed a small, roundish, low echogenic lesion measuring 8mm in diameter in the left lower peripheral zone of the prostate. The volume of prostate was 27cc and biopsy revealed adenocarcinoma (Gleason score 7). MRI confirmed the presence of a small nodular lesion in the left peripheral zone without evidence of local invasion, and bone scintigraphy was unremarkable. The tumor was staged as T2a. We performed permanent implantation of Iodine-125 seeds using Mick procedure. The patient experienced immediate post-implant irritation of the bladder and urethra with hematuria. Follow up CT and radiography showed all seeds were remained in the same prostate as implanted. Follow up serum PSA was 1.85ng/ml at 3 months and 0.62ng/ml at 9 months after the procedure.
Adenocarcinoma ; Aged ; Biopsy ; Brachytherapy ; Follow-Up Studies ; Hematuria ; Humans ; Korea* ; Magnetic Resonance Imaging ; Nocturia ; Prostate ; Prostatectomy ; Prostatic Neoplasms* ; Radiography ; Radionuclide Imaging ; Ultrasonography ; Urethra ; Urinary Bladder

Intrasellar location of schwannoma is extremely rare, although intracranial schwannomas account for up to 8% of all primary brain tumors. An unusual case of an intrasellar schwannoma radiographically and clinically simulating a pituitary adenoma is reported. A 39-yr-old man presented a 10-month history of visual disturbance and decreased libido. Neurological examination showed poor visual acuity of both eyes with bitemporal hemianopsia. Computed tomography and magnetic resonance imaging showed a sellar tumor with suprasellar extension. Pituitary adenoma was considered as a preoperative diagnosis. The tumor was removed through a trans-sphenoidal approach. Microscopic examination of the tumor revealed schwannoma.
Adult ; Brain Neoplasms/diagnosis/metabolism/*pathology/surgery ; Diagnosis, Differential ; Follow-Up Studies ; Humans ; Magnetic Resonance Imaging ; Male ; Neurilemmoma/diagnosis/metabolism/*pathology/surgery ; Pituitary Neoplasms ; Prolactinoma ; Tomography, X-Ray Computed ; Visual Fields

OBJECTS: Because of the nonspecific nature of symptoms in tuberculous spondylitis, a delay in the diagnosis can result in progressive neurologic deficits. The authors evaluate the clinical and the radiological results of the 10 cases of surgically treated tuberculous spondylitis. CLINICAL MATERIALS AND METHODS: We retrospectively analyzed the medical records of 10 patients with tuberculous spondylitis who were treated between February 1996 and March 2000. Six patients were female, and four were male. Mean age was 43 years old, and mean follow-up period was 20.5 months. All patients were treated with 12 months of antituberculous medication postoperatively, and were followed by complete blood count, ESR, spine X-ray and MRI. RESULTS: The lumbar spine was involved in 5 patients, the thoracic in 4, and the thoracolumbar in one. The infected vertebral bodies were 2.8 in average. The associated lesions were pulmonary tuberculosis in 3 cases, and renal tuberculosis in one. Five patients were treated by anterior debridement and fusion with bone graft using anterior instrumentation, 2 with anterior debridement and fusion with bone graft(Hong Kong procedure only), 1 with Hong Kong procedure with posterior spinal instrumentation, and 2 were managed with posterior debridement and posterior spinal instrumentation. All patients improved after operation, and the average kyphotic angle decreased postoperatively. Postoperatively, one patient had a fistula at the operative site. CONCLUSION: The debridement and minimal level fusion of motion segment with instrument fixation is one of surgical option for tuberculous spondyltis to preserve the spine motion segment as much as possible. Spine instability and kyphosis were prevented by anterior and posterior spinal instrumentation. But, large number of cases and longer period follow-up study in future will be needed to confirm the long term results.
Adult ; Blood Cell Count ; Debridement ; Diagnosis ; Female ; Fistula ; Follow-Up Studies ; Hong Kong ; Humans ; Kyphosis ; Magnetic Resonance Imaging ; Male ; Medical Records ; Neurologic Manifestations ; Retrospective Studies ; Spine ; Spondylitis* ; Transplants ; Tuberculosis, Pulmonary ; Tuberculosis, Renal