1.Generation and characterization of a monoclonal antibody with high species-specificity to Schistosoma japonicum glutathione S-transferase.
Jung Hwan KIM ; Jung Hyun PARK ; Sung Kyu JU ; Myung Kyu LEE ; Kil Lyong KIM
Immune Network 2001;1(3):187-195
No abstract available.
Glutathione Transferase*
;
Glutathione*
;
Schistosoma japonicum*
;
Schistosoma*
2.A Case of Kerion Ceisi Caused by Trichophyton Verrucosum and Treated with Itraconazole.
Moo Kyu SUH ; Yeol Oh SUNG ; Jung Ran KIM
Korean Journal of Dermatology 1994;32(1):124-129
We report a case of kerion celsi caused by Trichophyton(T.) verrucosum in a 15-year-old male, who showed a trender, indurated, swollen, boggy mass exuding pus on the frontal scalp for 15 days. Culture from a scalp lesion of patient and infected cattles on Sabouraud dextrose agar showed T. verrucosum. Therapy was initiated on with 100mg of itraconazole daily with almost complete resolution of scalp lesion one month after treatment. During the one month follow up reriod, scalp lesion showed new black hairs and no recurrence.
Adolescent
;
Agar
;
Follow-Up Studies
;
Glucose
;
Hair
;
Humans
;
Itraconazole*
;
Male
;
Recurrence
;
Scalp
;
Suppuration
;
Tinea Capitis
;
Trichophyton*
3.Endoscopic Surgery for a Benign Esophageal Stensosis without open Thoracotomy.
Sung Kyu ROH ; Soo Jung LEE ; Koing Bo KWUN
Korean Journal of Gastrointestinal Endoscopy 1993;13(1):37-39
Surgery for a mid-esophageal lesion requires an open thoracotomy, But authors resected out a stenotic thoracic esphageal lesion with laparoscopic instrument without open thoracotomy. The patient was 50 years old woman with a long history of progressive dyaphagia. A small (3 cm in diameter) smooth ovoid submucosal mass lesion was found at 26 cm distal from incisor on both esophagoscopy and esophagogram. Two 5 mm and two 10 mm trocars were inserted into the right pleural cavity under general anesthesia with double lumen endotracheal tube, An induced pneumothorax by insuffulation of CO2 gas made lung collapse and a good exposure of esophagus. Transorally introduced esophagoscope helped to demonstrate the exact location of lesion and also to give a guide at safe excision of mass with prevention of mucosal perforation. The lesion was found to be a congromeration of an inflammed hilar lympnode and hypertorphic esophageal muscle. The entire lesion was carefully dissected from esphageal mucosa and resected out en bloc. A chest tube was introduced through a trocar site. The lung was reinflated immediately. Post-operatively patient was very comfortable. Laparoscopic surgery is very effective and safe, and it could be applied for the resection of lung bullae, benign pulmonary neoplasm and for an excision of benign esophageal tumor.
Anesthesia, General
;
Chest Tubes
;
Esophagoscopes
;
Esophagoscopy
;
Esophagus
;
Female
;
Humans
;
Incisor
;
Laparoscopy
;
Lung
;
Lung Neoplasms
;
Middle Aged
;
Mucous Membrane
;
Pleural Cavity
;
Pneumothorax
;
Pulmonary Atelectasis
;
Surgical Instruments
;
Thoracotomy*
4.A case of multiple bowen's disease associated with adenoid basal cell carcinoma.
Moo Kyu SUH ; Yeol Oh SUNG ; Jung Ran KIM
Korean Journal of Dermatology 1993;31(6):983-987
AFX is a fibrohistiocytic tumor which usually shows benign clinical rocess despite malignant histolgy. We report a case of AFX showing storiform pattern distribution of tumor cells which developed on the right temple area of a 70-year-old woman.
Adenoids*
;
Aged
;
Bowen's Disease*
;
Carcinoma, Basal Cell*
;
Female
;
Humans
5.Anterior Interbody Fusion to the Cervical Spine for the Range of Motion of the Adjacent Unfused Cervical Intervertebral Joints.
Jun Kyu LEE ; Jae Sung AHN ; Hyun Tae JUNG
Journal of Korean Society of Spine Surgery 1997;4(1):52-58
No abstract available.
Joints*
;
Range of Motion, Articular*
;
Spine*
6.Clinical Study on Congestive Heart Failure.
Kyu Sung RIM ; Jung Sang SONG ; Jong Hoa BAE
Korean Circulation Journal 1975;5(2):53-59
An analytical observation was carried out on clinical symptoms, physical findings, etiology, precipitating factors, pulse rate, and blood pressure manifested by 115 patients admitted to the Kyung hee university Hospital under the diagnosis of congestive heart failure for a period of October 1971 to September 1974. The results were as follows: 1. The disease affected female 1.4 times more frequently than male and occured most frequently in the 6th decade (26.1%), and its incidence decreased in the 7th decade (22.6%). 2. The important causes of congestive heart failure were hypertensive heart disease (39.7%), rheumatic heart disease (26.1%), cor pulmonale (13.9%), atherosclerotic heart disease (6.1%), postpartum heart failure (6.1%) and pericardial disease (3.5%). The unknown etiology was 3.5% of all cases. 3. The most common precipitatiog factors of the 106 patients of congestive heart failure were infections (59.5%), especially in the upper respiratory tract infection (37.8%). The physical exertion, pregnancy and labor, psychic stress, angina, myocardial infarction, and discontinuation of Tapazol and digitalis were followed. 4. The most common symptoms and signs were the dyspnea (93%), and the next common were pulmonary rales (65.2%), hepatomegaly (59.1%), distention of cervical vein (55.7%), pitting edema (44.3%) and cardiac murmur (38.3%) on admission. 5. The increased pulse rate over 101/min. was about 38.3%, but less than 60/min. was found in 4.3% only. 6. The electrocardiographic findings were abnormal except one case out of 107 cases. The left ventricular hypertrophy (48.1%), atrial fibrillation (24.5%), and bundle branch block (21.7%) were frequently observed. 7. The range of systolic blood pressure measured in 43 patients who had been suffered from hypertensive heart disease were disclosed that 221-240 mmHg (23.3%), 161-180mmHg (20.9%), and 181-200mmHg (20.9%) in order.
Atrial Fibrillation
;
Blood Pressure
;
Bundle-Branch Block
;
Diagnosis
;
Digitalis
;
Dyspnea
;
Edema
;
Electrocardiography
;
Estrogens, Conjugated (USP)*
;
Female
;
Heart Diseases
;
Heart Failure*
;
Heart Murmurs
;
Heart Rate
;
Hepatomegaly
;
Humans
;
Hypertrophy, Left Ventricular
;
Incidence
;
Male
;
Myocardial Infarction
;
Physical Exertion
;
Postpartum Period
;
Precipitating Factors
;
Pregnancy
;
Pulmonary Heart Disease
;
Respiratory Sounds
;
Respiratory Tract Infections
;
Rheumatic Heart Disease
;
Veins
7.Clinical Study on Congestive Heart Failure.
Kyu Sung RIM ; Jung Sang SONG ; Jong Hoa BAE
Korean Circulation Journal 1975;5(2):53-59
An analytical observation was carried out on clinical symptoms, physical findings, etiology, precipitating factors, pulse rate, and blood pressure manifested by 115 patients admitted to the Kyung hee university Hospital under the diagnosis of congestive heart failure for a period of October 1971 to September 1974. The results were as follows: 1. The disease affected female 1.4 times more frequently than male and occured most frequently in the 6th decade (26.1%), and its incidence decreased in the 7th decade (22.6%). 2. The important causes of congestive heart failure were hypertensive heart disease (39.7%), rheumatic heart disease (26.1%), cor pulmonale (13.9%), atherosclerotic heart disease (6.1%), postpartum heart failure (6.1%) and pericardial disease (3.5%). The unknown etiology was 3.5% of all cases. 3. The most common precipitatiog factors of the 106 patients of congestive heart failure were infections (59.5%), especially in the upper respiratory tract infection (37.8%). The physical exertion, pregnancy and labor, psychic stress, angina, myocardial infarction, and discontinuation of Tapazol and digitalis were followed. 4. The most common symptoms and signs were the dyspnea (93%), and the next common were pulmonary rales (65.2%), hepatomegaly (59.1%), distention of cervical vein (55.7%), pitting edema (44.3%) and cardiac murmur (38.3%) on admission. 5. The increased pulse rate over 101/min. was about 38.3%, but less than 60/min. was found in 4.3% only. 6. The electrocardiographic findings were abnormal except one case out of 107 cases. The left ventricular hypertrophy (48.1%), atrial fibrillation (24.5%), and bundle branch block (21.7%) were frequently observed. 7. The range of systolic blood pressure measured in 43 patients who had been suffered from hypertensive heart disease were disclosed that 221-240 mmHg (23.3%), 161-180mmHg (20.9%), and 181-200mmHg (20.9%) in order.
Atrial Fibrillation
;
Blood Pressure
;
Bundle-Branch Block
;
Diagnosis
;
Digitalis
;
Dyspnea
;
Edema
;
Electrocardiography
;
Estrogens, Conjugated (USP)*
;
Female
;
Heart Diseases
;
Heart Failure*
;
Heart Murmurs
;
Heart Rate
;
Hepatomegaly
;
Humans
;
Hypertrophy, Left Ventricular
;
Incidence
;
Male
;
Myocardial Infarction
;
Physical Exertion
;
Postpartum Period
;
Precipitating Factors
;
Pregnancy
;
Pulmonary Heart Disease
;
Respiratory Sounds
;
Respiratory Tract Infections
;
Rheumatic Heart Disease
;
Veins
8.Evaluation of EL-ANA/6 Profiles for Specific Antinuclear Antibodies.
Han Sung KIM ; Hee Jung KANG ; Kyu Man LEE
Korean Journal of Clinical Pathology 1997;17(4):643-649
BACKGROUND: Identification of specific antinuclear antibodies is useful for the diagnosis, subclassification and determination of prognosis in autoimmune disorders. In many diseases, multiple autoantibodies are detected, and simultaneous detection of multiple autoantibodies has been shown to be useful. Recently, a commercial kit (EL-ANA/6 profiles, TheraTest Laboratories, USA) losing enzyme-linked immunosorbent assay (ELISA) method for detection of six specific autoantibodies is avallable. In this study, we attempted to compare the results of EL-ANA/6 profiles with those of routinely used methods and evaluated usefulness of EL-ANA/6 profiles. METHODS: EL-ANA/6 profiles were performed with 28 sera which were positive for fluorescent antinuclear antibody (FANA) Simultaneously we tested anti-dsDNA antibodies with immnofluorescent (If) method and anti-Sm, anti-RNP, anti-SSA and anti-SSB antibodies with double immunodiffusion (DID). To evaluate specificity, EL- ANA/6 profiles tests were performed on 10 sera from healthy blood donors. RESULTS: Ten sera of healthly blood donors were all negative for EL-ANA/6 pro biles. In the results of EL-ANA/6 profiles on sera positive for FANA, the concordance rate with IF method for the anti-dsDNA antibodies was 89.3% (25/28) and the con- cordance rates with DID for anti-Sm, anti-Sm/RNP, anti-SSA and anti-SSB antibodies were 85.7% (24/28), 82.1% (23/28), 92.9% (26/28) and 82.1% (23/28), respectively. In 16 discordant settings, thirteen (81.3%) were negative on DID and positive on EL-ANA/6 profiles. CONCLUSIONS: The results of the EL-ANA/6 profiles show good concordance rates with If and DID. EL-ANA/6 profiles showing quantitative profiles for multiple autoantibodies is useful for diagnosis and tool)ow-up of autoimmune disorders.
Antibodies
;
Antibodies, Antinuclear*
;
Autoantibodies
;
Bile
;
Blood Donors
;
Diagnosis
;
Enzyme-Linked Immunosorbent Assay
;
Humans
;
Immunodiffusion
;
Prognosis
;
Sensitivity and Specificity
9.Radiologic analysis of ossification of the posterior longitudinal ligament of the spine
Kyu Bo SUNG ; Seung Ro LEE ; Jung Jin KIM
Journal of the Korean Radiological Society 1983;19(3):517-522
Since calcification or ossification of the posterior longitudinal ligament of the spine was first described inJapan in 1960 by Tsukimoto, Terayama used the term of OPLL(Ossification of Posterior Longitudinal Ligament) in1964 and mainly reported in Japanese. But recently, the incidence of the OPLL has been reported increasing amongthe non-Japanese. Because of the OPLL may be associated wtih severe neurologic symptoms, which need to havesurgical decompression, exact diagnosis and analysis are necessary. The OPLL can be diagnosed by simple spine,conventional tomography, myelography and CT. Authors analysed radiologic findings of the OPLL in 8 patients, whowere diagnosed by simple spine. Conventional tomography, myelography and CT, and then performed spinal operation,at Hanyang University Hospital from March 1980 to June 1983. The results were as followings; 1. The age range wasbetween 45 and 63 years and most prevalent age was 6th decades(63%). 2. All of the patients were male. 3. All ofthe OPLL occurred in the cervical spine and predominant at the level of C3,4 (48%). 4. The most common length ofthe OPLL was 2 vertebral level. 5. Except one, which was discontinuous at the level of disc space, all of the OPLLwere continuous in length. 6. 7 of 8 OPLL were located in the midline, but one was in right. 7. The OPLL seemed tocorrelate with spondylotic changes. 8. Of all diagnostic procedure, CT provided better and exact visualization ofthe lesion with axial scan and sagittal reconstruction.
Asian Continental Ancestry Group
;
Decompression
;
Diagnosis
;
Humans
;
Incidence
;
Longitudinal Ligaments
;
Male
;
Myelography
;
Neurologic Manifestations
;
Spine
10.Study on the lead exposure of workers in a litharge making industry.
Sang Bok LIM ; Jung Kyu LIM ; Sung Soo LEE ; Kyu Dong AHN ; Byung Kook LEE
Korean Journal of Preventive Medicine 1995;28(4):875-884
In order to investigate the level of lead exposure of workers in litharge making industry and to evaluate how lead exposure, personal habit such as smoking and drinking affect the prevalence of lead related symptoms and other study variables, we investigate 114 workers(24 office workers and 90 lead exposed workers) in a litharge making industry. Study variables chosen were blood lead(PbB), zinc protoporphyrin in whole blood(ZPP), Hemoglobin(Hb), hematocrit (Hct), SGOT and SGPT. symptom questionnaires which had 15 lead exposure related symptoms were provided to all workers and filled up by themselves and reconfirmed by physician. The results obtained were as follows; 1. The mean value of PbB, ZPP and SGOT in lead exposed group were higher than those of non-exposed group, and there were no differences of means in other study variables. 2. The smoking and drinking rate of study subjects were 65.8% and 71.0% as a whole. Smoking rates were lower in non-exposed group than exposed group, but drinking rate were not. 3. There were no differences of mean values of study variables between smoker and non-smoker in non-exposed and exposed group, but there was a difference of mean value of SGOT between drinker and non-drinker in lead exposed group. 4. while the symptom prevalence of lead exposed group were higher in neuromuscular category than non-exposed group, those of non-exposed group were higher or same with exposed group in gastrointestinal and general symptom category. 5. The symptom prevalence of smoker were higher than non-smoker regardless of exposure. 6. The symptom prevalence of drinker were only higher in gastrointestinal symptom category than non-drinker. 7. In multiple stepwise regression analysis of lead related symptoms as dependent variable and blood lead, smoking habit, drinking habit and work duration as independent variables, drinking habit contributed to the gastrointestinal symptom category, whereas blood lead and smoking contributed to the neuromuscular symptom category. For the total symptoms work duration and smoking habit contributed significantly.
Alanine Transaminase
;
Aspartate Aminotransferases
;
Drinking
;
Hematocrit
;
Humans
;
Prevalence
;
Surveys and Questionnaires
;
Smoke
;
Smoking
;
Zinc