A) Bacteriological study and sensitivity test against antimicrobial agents were made on 126 cases of infantile and childhood shigellosis treated at pediatric epartment of St. Vincent hospital from April, 78 to September, 80. The results are follows: 1. Sh. flexneri was most frequently isolated(86.5%) and the next was Sh. sonnei(13.5%). 2. The percentage of resistant strains against antimicrobial agents. Ampicillin: 95.2% Carbenicillin : 90.5% Cephalothin: 78.6% Choloramphenicol: 95.2% Gentamicin: 20.6% Kanamycin: 23.8% Lincomycin: 100% Methicillin: 100% B) The effect of rifampin on bacteriological cure and clinical course in group B shigellosis of sixty-four hospitalized children from one year to five years old age were compared with other antibiotics. gentamicin, ampicillin and trimethoprim-sulfamethoxazole. Based on our study, rifampin was most effective drug in curing of clinical symptoms of shigellosis and eradicating the organisms from stool, and gentamicin was similar effect. Trimethoprim-sulfamethoxazole twas less effective than rifampin and gentamicin, but more effective than ampicillin which has no appreciable effect on the course of shigellosis.
Ampicillin ; Anti-Bacterial Agents ; Anti-Infective Agents* ; Carbenicillin ; Cephalothin ; Child ; Child, Hospitalized ; Dysentery, Bacillary* ; Gentamicins ; Humans ; Kanamycin ; Lincomycin ; Methicillin ; Rifampin* ; Trimethoprim, Sulfamethoxazole Drug Combination

An imaginative innovation to shorten hospital stays as a means to reduce patient charges, is out-patient surgery. This procedure also minimized the inconvenience and disruption of the family unit, reduced the opportunities for cross-infection, and freed hospital beds for the more seriously ill patients Since the concept of out-patient surgical service was organized, managed, and performed in the Hanyang Medical Center, we had experience of 132 ambulatory anesthetics during the last two years (from Jan. 1974. to Dec. 1975 ). The results are summarized as follower 1. Preanesthetic examination should be routinely checked with Hb., Hct., urinalysis and chest x-ray. 2. Premedication should be administered preanesthetically, atropine sulfate intravenously. 3. ASA class 1 patients should be chosen for short (less than 1 hour) procedures. 4. Anesthesia is induced with Epontol+S.C.C. and maintained with Halothane+N2O+O2. 5. We suggest that ambulatory anesthesia should be more carefully planned, organized, and managed.
Anesthesia* ; Anesthetics ; Atropine ; Humans ; Length of Stay ; Outpatients ; Premedication ; Thorax ; Urinalysis

In the 1st two years (From April 1975 to March 1977), we have had experience with 15 surgical infant patients undergoing general inhalation anesthesia with the "Loasco" Infant Ventilator. The "Locsco" Infant Ventilator is designed for the ventilation of neonates and infants on the lines of an open system with a gas mixture of air-oxygen or oxygen-anesthetics. However we used it with a gas mixture of halothane-N2O-oxygen, This study was undertaken to evaluate the value of ventilatory support with the "Loosco" infant Ventilator during general inha!ation anesthesia for 15 surgical patients whose age was less than 2 years of age. The blood gas analysis showed slight under ventilation combined with metabolic acidosis during the first 15 minutes, in which respiratory frequency was set at 30 times per minute, but the ventilation was gradually improved by increase in respiratory frequency to 35 times per minute during the lost 20 minute. In this study, we considered. the important factors which influenced the value of the blood gas analysis. Not only careful anesthetic management to keep the airway and to convect cardiovascular derangement, but also frequent and repeated blood gas analysis and its accurate interpretation were stressed for using the "Loosco" Infant Ventilator during pediatric general anesthesia.
Acidosis ; Anesthesia ; Anesthesia, General ; Anesthesia, Inhalation ; Blood Gas Analysis ; Humans ; Infant* ; Infant, Newborn ; Ventilation ; Ventilators, Mechanical*

Clinical problem occuring in the early post operative period after cardiopulmonary bypass may ne related to the altered function of capillary bed which was affected by activation of complement system. This is so called post perfusion syndrome. We selected 20 patients with confirmed congenital heart disease by cariac catheterization. We studied the changes in the C3 , immunolglobulins, total protein, and WBC count while performing open heart surgery. The results were as followed. 1. C3 level was lowest during cardiopulmonary bypass and returned to the normal level after 8 days. 2. Each immunoglobulin level decreased just after cardiopulmonary bypass, especially the IgG level, and immunoglobulins slowly returned to the normal range after 8 days. 3. Serum total protein level and electrophoretic fractions were comperatively reduced as much as immunoglobulin levels. 4. WBC count was lower just before cardiopulmonary bypass than baseline.
Capillaries ; Cardiopulmonary Bypass* ; Catheterization ; Catheters ; Complement System Proteins* ; Heart Defects, Congenital ; Humans ; Immunoglobulin G ; Immunoglobulins ; Oxygenators ; Perfusion ; Reference Values ; Thoracic Surgery