1.A Case of Chromonycosis.
Korean Journal of Dermatology 1990;28(3):345-348
We report a 55-year-old male, who has had erythematous, scaly, verrucous plaque on the left lower leg. About 1 year ago, rice sized erythematous papule on the left lower leg was developed. The lesion had been aggravated abruptly and rapidly in size since about one month ago. Histopathologic finding showed clusters of fungal spores in the upper dermis and intraepidermal microabscesses. The patient had been treated with wide excision and intravenous injection of amphotericin B. We observed a good response without evidence of recurrence.
Amphotericin B
;
Chromoblastomycosis
;
Dermis
;
Humans
;
Injections, Intravenous
;
Leg
;
Male
;
Middle Aged
;
Recurrence
;
Spores, Fungal
2.Development of Squamous cell Carcinoma in Epidermolysis Bullosa Dystrophical Recessive.
Sung Ku AHN ; Seung Hun LEE ; Sung Nack LEE
Korean Journal of Dermatology 1990;28(2):240-244
No abstract available.
Carcinoma, Squamous Cell*
;
Epidermolysis Bullosa*
3.A Case of Spindle Cell Lipoma.
Sung Ku AHN ; Won Hyoung KANG ; Sung Nack LEE
Korean Journal of Dermatology 1990;28(6):810-813
A 50-year-old man developed 3cm sized, well-marginated, subcutaneous mass on the right upper back. Histopathologic finding showed the lipomatous tissue was replaced by a mixture of uniform spindle cells and mature fat cells that were closely associated with a mucoid matrix and a varying number of collagen fibers. The patient had been treated with excision and showed no evidence of recurrence.
Adipocytes
;
Collagen
;
Humans
;
Lipoma*
;
Middle Aged
;
Recurrence
4.Ultrastrural Observation in A Case of Palmar Fibromatosis.
Sung Ku AHN ; Dong Sik BANG ; Sung Nack LEE
Korean Journal of Dermatology 1990;28(5):637-641
We herein report a case of palmar fibromatosis, who was 78-year-old male and had had multiple variable-sized subcutaneous hard nodules on the left palm for 2 months. Histopathologic findings of the lesion revealed that the nodules were highly cellular, containing numerous spindle shaped cells. Ultrastructurally, intracytoplasmic micrcfilaments were present, and the nuclei were extremely indented by one or more transverse folds. These findings suggested the cells were myofibroblasts.
Aged
;
Fibroma*
;
Humans
;
Male
;
Myofibroblasts
5.Comparison in Expression of CD 1 , HLA - DR and ICAM - 1 of Follicular Keratinocytes from a Lesion and a Non - Lesional Scalp of Alopecia Areata.
Won Soo LEE ; Sung Ku AHN ; Seung Hun LEE
Korean Journal of Dermatology 1995;33(5):873-879
BACKGROUND: Primary targit injured from the immunologic mechanism of alopecia areata is not definitely confirmed although alopecia areata is regarded as a disease occuring from certain im munologic process. Recently, par ticular interest has been focused on the follicular keratinocytes which show morphologic and anigenic alterations in active lesions. Another important point is the subclinical state hypothesi. It is based upon the observation that the patterns of T lymphocytes infiltration and ultrastructural changes of dermal papilla cells are nearly identical in active lesions and in non-lesional areas of alopecia areata. OBJECTIVE: The purpose of this study is to determine and to compare the aberrant expression of HLA-DR, CD1 and ICAM-1 on the follicular keratinocytes from the active alopecia areata lesion, stationary lesion and non-lesional scalp. METHODS: We performed a n immunohistochemical study, using the streptavidin system to compare the patterns of HLA-DR, CD1 and ICAM-1 immunoreactivity in the follicular keratinocytes in five active alopecia lesions two stationary lesions and non-lesional scalp specimens among four active and two stationary patients, and two normal control scalp specimens. RESULTS: In the active aloecia lesions, the HLA-DR and ICAM-1 immunoreactivity was observed in some patients while CD1 immunoreactivity was observed in all the patients. In the sta tionary alopecia lesions, none of the HLA-DR or CD1 or ICAM-1 immunoreactivity was observed as was the case in the norrial control scalp specimens. In the non-lesional normal scalp specimens, the HLA-DR, CD1 and ICAM-1 immunoreactivity showed nearly the same patterns as those in the acute alopecia leions. CONCLUSION: The aberrant antigenic alterations, especially CD1 expression of follicular keratinocytes are likely to be asociated with the active progress of alopecia areata lesions. These antigenic alterations were also observed in non-lesional scalp as well as alopecia areata lesions in the very similar patterns.
Alopecia Areata*
;
Alopecia*
;
HLA-DR Antigens
;
Humans
;
Intercellular Adhesion Molecule-1
;
Keratinocytes*
;
Scalp*
;
Streptavidin
;
T-Lymphocytes
6.A Case of Atypical Sessile Dermatofibroma.
Yung Jae LEE ; Sung Ku AHN ; Seung Hun LEE
Annals of Dermatology 1993;5(2):130-132
We report a case of a morphologic variant of dermatofibroma. A coin sized, brownish, shinny, somewhat fibrotic pedunculated tumor in a 39-year-old male was diagnosed as a sclerosing hemangioma, a type of dermatofibroma histopathologically. Its dome shape morphology was unusual in comparison with the typical morphology of dermatofibroma that we know.
Adult
;
Histiocytoma, Benign Fibrous*
;
Humans
;
Male
;
Numismatics
7.Localized Idiopathic Lipoatrophy Showing Involutional Histopathology.
Seung Min LEE ; Sung Ku AHN ; Seung Hun LEE
Annals of Dermatology 1994;6(2):200-203
We present cases of localized idiopathic lipoatrophy occurring in two women. A 19-year-old girl had symmetrically distributed annular telangiectatic atrophy on both buttocks and a 44-year-old female had annular telangiectatic atrophy on the right buttock. The histopathologic findings of these lesions revealed numerous capillaries, various sized lobules with small round or spindle shaped cells on a background of hyaline material in subcutaneous layer. Two cases of lipoatrophy which shows the involutional phase are reported.
Adult
;
Atrophy
;
Buttocks
;
Capillaries
;
Female
;
Humans
;
Hyalin
;
Young Adult
8.A Case of Secondary Telangiectasia Associated with an Operation.
Nam Soo KIM ; Seung Hun LEE ; Sung Ku AHN
Korean Journal of Dermatology 1994;32(6):1103-1106
Telangiectasia is characterized by permanently dilated small vessels usually arising from the suprapapillary plexus of venule capillaries, or arterioles. It may be etvlogically divided into the primary and secondary types. Rosacea, varicose vein, prolonged sun xvsure, radiation, and physical trauma may be the causes of secondary telangiectasia. We report herein a case of secondary telangiectasia associated which operation for a femur fracture.
Arterioles
;
Capillaries
;
Femur
;
Rosacea
;
Solar System
;
Telangiectasis*
;
Varicose Veins
;
Venules
9.Alopecia Associated with Occult Syringoma.
Won Soo LEE ; Kyun Tae KIM ; Sung Ku AHN
Korean Journal of Dermatology 1994;32(1):163-166
Occult syringoma means a clinically inapparent tumor of the swea gland that are histologically similar but not identical with the common syringoma. They may occur in a variety of inflammatory skin lesions and cutaneous neoplaams as a reactive process. We report herein a case of diffuse alopecia areata associated with occult syringoma in the scalp of a 57-year-old man. Our patient developed progressive, fairly well circ amscribed patches of alopecia and diffuse hair loss over a 1 month period. Histopathological examinaiion revealed non-scaring alopecia and a proliferation of eccrine ductal structures in the upper dermis. These ductal structures resembled syringoma. Only minimal focal fibrosis was occasionally observed arcund the hair follicles. We believe that occult syringona is a reactive process and is secondary to active inflarnmation or dermal fibrosis. It has been most commonly observed in scarring alobiecias but plays no significant role in the etiology of hair loss.
Alopecia Areata
;
Alopecia*
;
Cicatrix
;
Dermis
;
Fibrosis
;
Hair
;
Hair Follicle
;
Humans
;
Middle Aged
;
Scalp
;
Skin
;
Syringoma*
10.Phakomatosis Pigmentovascularis Type Ia.
Joon CHUNG ; Won Soo LEE ; Sung Ku AHN
Korean Journal of Dermatology 1994;32(3):537-541
Phakomatosis pigmentovascularis is characterized by the coexistence of pigmentary nevus and hemangioma. Since the term was first described by Ota et al in 1947, about 80 cases have been reported in the literature. In 1979, Hasegawa et al subclsssified the disorder into eight types : type I, nevus flammeus and nevus pigmentosus et verrucosus, type II, nevus flamme is and dermal melanocytosis, type III nevus flammeus and nev.us spilus, type IV, nevus flammeus, dermal melanocytosis and nevus spilus. Each type is subdivided into localized(a) and systemic(b) types, A 25-year-old male had brown papules on the left knee and thigh and purple patches on the left leg that had been present for approximately 7 years. He had no concon ittant systemic disease. The histopathologic findings on brown papules and purple patches are compatible with epidermal nevus and nevus flammeus respectively. We herein report a case of phakomatosis pigmentovascularis type I a.
Adult
;
Down Syndrome
;
Hemangioma
;
Humans
;
Knee
;
Leg
;
Male
;
Neurocutaneous Syndromes*
;
Nevus
;
Port-Wine Stain
;
Thigh