1.Antitumor effects of recombinant human interferon-alpha and gamma on human malignant melanoma xenograft in nude mice and alteration in morphology and immunologic parameters.
Kyung Ja JO ; Sung Hee PARK ; Sang Kook LEE
Journal of the Korean Cancer Association 1993;25(1):33-46
No abstract available.
Animals
;
Heterografts*
;
Humans*
;
Interferon-alpha*
;
Melanoma*
;
Mice
;
Mice, Nude*
2.Prognostic Parameters in Moderate or Severe Diffuse Axonal Injury.
Sang Kook LEE ; Kwan PARK ; Young Baeg KIM ; Byung Kook MIN ; Sung Nam HWANG ; Jong Sik SUK ; Duck Young CHOI
Journal of Korean Neurosurgical Society 1990;19(8-9):1123-1128
A retrospective study 40 patients with moderate or severe diffuse axonal injury which is defined as posttraumatic coma for over 24 hours without mass lesions or ischemic insults was conducted in order to identify prognostic parameters. The sign of hypothalamic damage and motor reactivities of 40 patients were reviewed and compared to the outcome. The results were as follows ; 1) The ratio of male to female was about 3 to 1 and the peak incidence was at the first decade. 2) Of abnormal brain stem signs, fever of central origin was observed at the early posttraumatic phase and correlated with nonrecovery of consciousness(P<0.05). 3) Of abnormal brain stem signs, abnormal ADH secretion was significantly correlated with nonrecovery of consciousness(P<0.005). 4) Abnormal motor reactivity to pain was significantly correlated with nonrecovery of consciousness(P<0.005). 5) In the group of recovery of consciousness, initial Glasgow coma scale in 40 patients with moderate or severe DAI was significantly correlated with their outcome(P<0.005).
Brain Stem
;
Coma
;
Consciousness
;
Diffuse Axonal Injury*
;
Female
;
Fever
;
Glasgow Coma Scale
;
Humans
;
Incidence
;
Male
;
Retrospective Studies
3.Nuchal Translucency Measurement in Normal Fetuses at 10 - 14 Weeks of Gestation I.
Kook LEE ; Dong Hyun CHA ; Sung Pok PARK ; Hee Jin PARK
Korean Journal of Obstetrics and Gynecology 2000;43(10):1822-1827
No abstract available.
Fetus*
;
Nuchal Translucency Measurement*
;
Pregnancy*
4.Upper Gastrointestinal Endoscopic Findings in Chronic Renal Failure Patients.
Jae Seok HWANG ; Young Woo KANG ; Sung Bae PARK ; Jeong Wook HER ; Sung Hoon AHN ; Soong Kook PARK
Korean Journal of Gastrointestinal Endoscopy 1992;12(2):215-220
It has been well known that variable complications oecur in multiple organs in chronic renal failure patients. Of them gastrointestinal complications are also variable including nausea, vomiting, gastritis, peptic ulcer, gastrointestinal bleeding, hepatitis, pancreatitis, telangiectasia, angiody- splasia etc. Of such complications the incidence of peptic ulcer had been known to be high, but after endoscopic study, the incidence of nonulcer mueosal lesion has been more common. So we evaluated tbe upper gastrointestinal mucosal lesion in chronic renal failure patients by endoscopic examination. 129 subjects(mean age, 42 years, creatinine clearance ratio<10 ml/min) participated in this study. After overnight fasting the subjects were premedicated with simethicon and benoxinate. The mucosal lesion was diagnosed by two endoscopists with observing the TV monitor of electronic endoscope Fujinon EVG-FP. Of the 129 patients, 78 patients(76%) were revealed to abnormal endoscopic finding. Of the abnormal findings, the incidence of gastritis was most common in 34.9%, and then gastic erosion, duodenal erosion, gastric petechiae, gastric telangiectasia, duodenitis, gastric ulcer, gastric xanthoma, esophageal erosion, duodenal ulcer, esophageal uicer in orders. There was no difference in abnormal finding according to therapeutic type. From our study, we conclude that the incidence of nonulcer mucosal lesion is higher than ulcer disease in chronic renal failure patient, moreover those lesion can be diagnosed only by endoseopy. So we think that upper gastrointestinal endoscopy is necessory for evaluation of upper gastrointestinal tract in chronic renal failure patient.
Creatinine
;
Duodenal Ulcer
;
Duodenitis
;
Endoscopes
;
Endoscopy, Gastrointestinal
;
Fasting
;
Gastritis
;
Hemorrhage
;
Hepatitis
;
Humans
;
Incidence
;
Kidney Failure, Chronic*
;
Nausea
;
Pancreatitis
;
Peptic Ulcer
;
Purpura
;
Stomach Ulcer
;
Telangiectasis
;
Ulcer
;
Upper Gastrointestinal Tract
;
Vomiting
;
Xanthomatosis
5.Coin perforation of the esophagus.
Sung Chul KIM ; Kook Yang PARK ; Shin Yeong LEE ; Chang Ho KIM
The Korean Journal of Thoracic and Cardiovascular Surgery 1991;24(3):306-309
No abstract available.
Esophagus*
;
Numismatics*
6.The Endotoxin Assay of Contaminated Titanium Implants following Various Techniques of Detoxification.
The Journal of the Korean Academy of Periodontology 2004;34(1):71-81
Peri-implantitis could be the result of biomechanical and occlusal overload as well as microbiologic invasion. The dental implant may be more susceptible to dental plaque than the natural tooth, as the predictability of a stable soft tissue attachment complex has not yet been confirmed. With the development of peri-implantitis, the implant surface would be exposed to the oral environment and becomes coated with bacteria. The objective of therapy for this condition is to regain integration of the implant with bone. Since fibroblast adherence to surfaces is impeded by endotoxin, it would seem that decontamination would be desirable to obtain maximum osseointegration. The purpose of this study was to determine whether various chemotherapeutic and mechanical treatments(distilled water, air-powder abrasive, hypersaturated citric acid, tetracycline) can detoxify contaminated titanium implant surface by means of kinetic LAL test. Experimental rough surface titanium disks were fabricated. All of them were divided into two groups(A.a group and P.g group) and each contaminated by A. actinomycetemcomitans and P. gingivalis suspension. Contaminated disks were treated with distilled water, air-powder abrasive, citric acid and tetracycline, and then all disks were placed into LPS-free water for elution. The results were as follows : 1. In A.a group, LPS elute level of all test groups were significantly lower than control group(p<0.05). 2. In A.a group, LPS elute level of test 2, test 3 and test4 groups were significantly lower than that of control group(p<0.05). But, among the test 2, test 3, test4 groups, the significant differences were not detected. 3. In P.g group, LPS elute level of test 2, test 3 and test 4 groups were lower than that of control group(p<0.05). But, among the test groups, the significant differences were not detected. From the result of this study, it would be concluded that air-powder abrasive, hypersaturated citric acid and tetracycline treatments may be effective at reducing endotoxin level on rough titanium implant surfaces, and can be clinically used. But the treatments in peri-implantitis differentially impact osseointegration making one method clinically superior. To gain this knowledges, further molecular biologic and histopathologic studies should be developed.
Bacteria
;
Citric Acid
;
Decontamination
;
Dental Implants
;
Dental Plaque
;
Fibroblasts
;
Osseointegration
;
Peri-Implantitis
;
Tetracycline
;
Titanium*
;
Tooth
;
Water
7.Analysis of routine test results for the diagnosis of paraxysmal nocturnal hemoglobinuria.
Sun Hee KIM ; Sung Sup PARK ; Chong Hyun YOON ; Han Ik CHO ; Byoung Kook KIM
Korean Journal of Clinical Pathology 1993;13(2):225-231
No abstract available.
Diagnosis*
;
Hemoglobinuria*
8.An unusual reduplication of the ileum in adulthood.
Sung Bum HONG ; Myung Suk SIM ; Dong Youb SUH ; Dong Sun PARK ; Jin Kook KANG
Journal of the Korean Surgical Society 1992;42(1):135-139
No abstract available.
Ileum*
9.Diverticulitis of the right colon.
Ik Jae LEE ; Kook Hyun SONG ; Joong Kil CHANG ; Oh Suk BAE ; Sung Dae PARK
Journal of the Korean Society of Coloproctology 1993;9(4):353-361
No abstract available.
Colon*
;
Diverticulitis*
10.Diffuse Lymphoid Hyperplsia of Gastric Antrum.
Sae Kil KEE ; Jung Wook HUR ; Yak Ho KIM ; Sung Hoon AHN ; Soong Kook PARK
Korean Journal of Gastrointestinal Endoscopy 1986;6(1):25-26
We experienced three young patients with diffuse lymphoid hyperplasia of the gastric antrum. The peculiar nodularity of the stomach in tliese patients is another cause of etat mammelanne in addition to hypertrophic gastritis and prominence of the areae gastricae. The etiology of the diffuse lymphoid hyperplasia of the gastric antrum is not known. The symptqm is not specific and not related to hitologic and gastroscopic finding but rather to psychological disturbance. We propose longstanding observation for the change of the nodularity.
Gastritis, Hypertrophic
;
Humans
;
Hyperplasia
;
Pyloric Antrum*
;
Stomach