1.Diffuse Lymphoid Hyperplsia of Gastric Antrum.
Sae Kil KEE ; Jung Wook HUR ; Yak Ho KIM ; Sung Hoon AHN ; Soong Kook PARK
Korean Journal of Gastrointestinal Endoscopy 1986;6(1):25-26
We experienced three young patients with diffuse lymphoid hyperplasia of the gastric antrum. The peculiar nodularity of the stomach in tliese patients is another cause of etat mammelanne in addition to hypertrophic gastritis and prominence of the areae gastricae. The etiology of the diffuse lymphoid hyperplasia of the gastric antrum is not known. The symptqm is not specific and not related to hitologic and gastroscopic finding but rather to psychological disturbance. We propose longstanding observation for the change of the nodularity.
Gastritis, Hypertrophic
;
Humans
;
Hyperplasia
;
Pyloric Antrum*
;
Stomach
2.Study on the lead exposure of workers in a litharge making industry.
Sang Bok LIM ; Jung Kyu LIM ; Sung Soo LEE ; Kyu Dong AHN ; Byung Kook LEE
Korean Journal of Preventive Medicine 1995;28(4):875-884
In order to investigate the level of lead exposure of workers in litharge making industry and to evaluate how lead exposure, personal habit such as smoking and drinking affect the prevalence of lead related symptoms and other study variables, we investigate 114 workers(24 office workers and 90 lead exposed workers) in a litharge making industry. Study variables chosen were blood lead(PbB), zinc protoporphyrin in whole blood(ZPP), Hemoglobin(Hb), hematocrit (Hct), SGOT and SGPT. symptom questionnaires which had 15 lead exposure related symptoms were provided to all workers and filled up by themselves and reconfirmed by physician. The results obtained were as follows; 1. The mean value of PbB, ZPP and SGOT in lead exposed group were higher than those of non-exposed group, and there were no differences of means in other study variables. 2. The smoking and drinking rate of study subjects were 65.8% and 71.0% as a whole. Smoking rates were lower in non-exposed group than exposed group, but drinking rate were not. 3. There were no differences of mean values of study variables between smoker and non-smoker in non-exposed and exposed group, but there was a difference of mean value of SGOT between drinker and non-drinker in lead exposed group. 4. while the symptom prevalence of lead exposed group were higher in neuromuscular category than non-exposed group, those of non-exposed group were higher or same with exposed group in gastrointestinal and general symptom category. 5. The symptom prevalence of smoker were higher than non-smoker regardless of exposure. 6. The symptom prevalence of drinker were only higher in gastrointestinal symptom category than non-drinker. 7. In multiple stepwise regression analysis of lead related symptoms as dependent variable and blood lead, smoking habit, drinking habit and work duration as independent variables, drinking habit contributed to the gastrointestinal symptom category, whereas blood lead and smoking contributed to the neuromuscular symptom category. For the total symptoms work duration and smoking habit contributed significantly.
Alanine Transaminase
;
Aspartate Aminotransferases
;
Drinking
;
Hematocrit
;
Humans
;
Prevalence
;
Surveys and Questionnaires
;
Smoke
;
Smoking
;
Zinc
3.Screening for In Vitro Antifungal Activity of Soil Bacteria Against Plant Pathogens.
Sung Hwan CHANG ; Jung Yeop LEE ; Ki Deok KIM ; Byung Kook HWANG
Mycobiology 2000;28(4):190-192
Antifungal bacteria for biological control of plant diseases or production of novel antibiotics to plant pathogens were isolated in 1997 from various soils of Ansung, Chunan, Koyang, and Paju in Korea. Sixty-four bacterial strains pre-screened from approximately 1,400 strains were tested on V-8 juice agar against eight plant pathogenic fungi using in vitro bioassay technique for inhibition of mycelial growth. Test pathogens were Alternaria mali, Colletotrichum gloeosporioides, C. orbiculare, Fusarium oxysporum f. sp. cucumerinum, F. oxysporum f. sp. lycopersici, Magnaporthe grisea, Phytophthora capsici, and Rhizoctonia solani. A wide range of antifungal activity of bacterial strains was found against the pathogenic fungi, and strain RC-B77 showed the best antifungal activity. Correlation analysis between inhibition of each fungus and mean inhibition of all eight fungi by 64 bacterial strains revealed that C. gloeosporioides would be best appropriate for detecting bacterial strains producing antibiotics with potential as biocontrol agents for plant pathogens.
Agar
;
Alternaria
;
Anti-Bacterial Agents
;
Bacteria*
;
Biological Assay
;
Chungcheongnam-do
;
Colletotrichum
;
Fungi
;
Fusarium
;
Gyeonggi-do
;
Korea
;
Magnaporthe
;
Mali
;
Mass Screening*
;
Phytophthora
;
Plant Diseases
;
Plants*
;
Rhizoctonia
;
Soil*
4.White Matter Microstructure Alterations in Schizophrenia With Auditory Verbal Hallucination: Diffusion Tensor Imaging Study
MyungJe SUNG ; Jina JUNG ; KiWon SONG ; Takjong JUNG ; Hae Kook LEE
Journal of Korean Neuropsychiatric Association 2024;63(1):76-82
Objectives:
To compare the white matter microstructure alterations in schizophrenia with auditory verbal hallucinations (AVHs) with normal persons using diffusion tensor imaging.
Methods:
Thirty-five schizophrenia patients with AVHs and 33 normal control persons were recruited from the National Forensic Hospital in Korea. The fractional anisotropy (FA) values of arcuate fasciculus (AF), Broca’s area, and Wernicke’s area were estimated from the diffusion tensor imaging data of each subject using the Johns Hopkins University-white matter tractography atlas to determine the difference in white matter integrity between schizophrenia patients with AVH and normal persons.
Results:
Compared to the normal control group, the FA values of AF (t=4.349, p<0.001) were higher in the normal control group. On the other hand, there were no significant differences in Broca’s area and Wernicke’s area.
Conclusion
Microstructural changes of AF are certainly involved in schizophrenia patients with AVHs.
5.Clinical and Electrophysiological Study on Guillain-Barre Syndrome.
Sung Hwan YUN ; Jung Sang HAH ; Sung Gyun JOO ; Yong Kook CHO ; Jung Hyun KIM ; Ji Yeun CHUNG
Yeungnam University Journal of Medicine 2005;22(1):52-61
BACKGROUND: Guillain-Barre syndrome is defined as a recognizable clinical entity that is characterized by rapidly evolving symmetric limb weakness, the loss of tendon reflexes, absent or mild sensory signs, and variable autonomic dysfunctions. This study evaluated the clinical and electrophysiological findings retrospectively. MATERIALS AND METHODS: Forty-five patients with Guillain-Barre syndrome, who were admitted to the Yeungnam University Hospital for six years from Jan. 1994 to Dec. 1999 were investigated. The correlation between the clinical manifestation and the electrophysiological study was evaluated. RESULTS: The male to female ratio was 1.8: 1 and there was a peak seasonal incidence in the winter. A preceding illness was noted in 66.7% of cases, and an upper respiratory tract infection was the most common one. The most common clinical manifestations were a loss of tendon reflex and ascending muscle weakness and paralysis. The cerebrospinal fluid examinations revealed, albuminocytologic dissociation in 33 cases (73.3%). Intravenous immunoglobulin therapy was performed in 29 cases (64.4%). The sequential electrophysiological abnormalities were most marked at 2 to 4 weeks after onset. At that time the most significant change was a decrease in the compound muscle action potential amplitude. These 45 patients with Guillain-Barre syndrome were subclassified using the clinical and electrophysiological data. CONCLUSION: The result in this study, concured with other research on the clinical and electrophysiological data of Guillain-Barre syndrome. However, an extensive and dynamic investigation is necessary to determine the reason for the peak seasonal incidence in winter.
Action Potentials
;
Cerebrospinal Fluid
;
Extremities
;
Female
;
Guillain-Barre Syndrome*
;
Humans
;
Immunization, Passive
;
Incidence
;
Male
;
Muscle Weakness
;
Paralysis
;
Reflex, Stretch
;
Respiratory Tract Infections
;
Retrospective Studies
;
Seasons
6.Follow-up Management State of Lead Battery Workers in Periodic Health Examination.
Gap Soo LEE ; Young HWANGBO ; Yong Bae KIM ; Hwa Sung KIM ; Jung Oh HAM ; Sung Soo LEE ; Kyu Dong AHN ; Byung Kook LEE ; Jung HUR
Korean Journal of Preventive Medicine 1996;29(4):733-746
To evaluate the follow-up management state and related factor of lead battery workers in periodic health examination as part of program of group occupational health service, author studied 293 workers with questionnaire on knowledge of results and follow-up management state and related factors, and compared the responses to their periodic health examination result charts. The results were as follows: 1. 252(86%) workers responsed that they had received the health examination result chart, but only 116(39.6%) workers responsed that they had been educated or explained about the result of health examination, and 11(57.9%) workers among 19 workers with non-occupational disease D, 101(44.3%) workers among 228 workers with non-occupational disease C, and 19(28.4%) workers among 67 workers with occupational disease C knew accurately their health examination results. 2. 78(24.8%) of the workers responsed that they had follow-up management, and contents of follow-up management were follow-up(36.6%), out-patient treatment(31%), change worksite(8.5%), temporary retirement(7.0%) and others(16.9%). 3. Most of the workers responsed that the health examination were necessary, but three-fourths of the workers responsed that the health examination had been superficial or that they didn't know. 4. In this study, follow-up management show significant association with only explanation or education about health examination result chart.
Education
;
Follow-Up Studies*
;
Humans
;
Knowledge of Results (Psychology)
;
Occupational Diseases
;
Occupational Health Services
;
Outpatients
;
Surveys and Questionnaires
7.Characteristics of posteroanterior cephalometric analysis in children with skeletal Class I malocclusion.
Sang Jin SUNG ; Yoon Shik MOON ; Jung Kook KIM ; Hyun Sung JUNG
Korean Journal of Orthodontics 2001;31(2):159-172
Three dimensional analysis of malocclusion and craniofacial deformation is essential for the successful orthodontic treatment. But the orthodontists are not familiar with diagnosis and treatment plane based on lateral cephalometric analysis. Since orthodontists do not posses a sufficient knowledge in standard value of posteroanterior cephalometric anaysis and of clinical importance for transverse jaw growth. In this study male(n=130) and female(n=171) aged from 6 to 16 and diagnosed as Class I malocclusion were selected to analysis width of cranium, maxilla and mandible on the posteroanterior cephalogram. The changes as a function of chronologic age and cervical vertebrae maturity index(CVMI) were examined. The proper regression model was selected by sex with polynominal regression models and method of variable selection. Mean of each measurements and 70% confidence interval of individual measurement according to age was assesed and a graphs were made. Results are as follows : 1. All the measurements for the width are gradually incresed as increase in chronologic age and CVMI. From the total amount of change between age 6 and 16, there is a tendency that mandibular width is broader than maxillary width and the width of male is broader than female. 2. There is no statistically significant sexual difference in Mx-Mn difference, Mx-Mn width differential, Mx/Mn ratio according to age and CVMI. 3. Mean of each measurement and 70% confidence interval of individual measurement according to age and sex were assessed and graphs were made for maxillary width, mandibular width, Mx-Mn difference, Mx/Mn ratio. 4. The width of maxilla and mandible in Korean children are broader than Western children during growth period.
Cervical Vertebrae
;
Child*
;
Diagnosis
;
Equidae
;
Female
;
Humans
;
Jaw
;
Male
;
Malocclusion*
;
Mandible
;
Maxilla
;
Skull
8.Effects of Platelet-derived Growth Factor on the Activity of Osteoblastic Cells.
Hyoung Ho CHOI ; Jung Keun KIM ; Sung Bin LIM ; Chin Hyung CHUNG
The Journal of the Korean Academy of Periodontology 1999;29(4):785-801
No abstract available.
Osteoblasts*
;
Platelet-Derived Growth Factor*
9.The Effect of Venovenous Extracorporeal Lung Assist on the Arterial Oxygen Tension in Hypoxic Dogs.
Kook Hyun LEE ; Byung Moon HAM ; Sung Eun JUNG
Korean Journal of Anesthesiology 1992;25(1):72-77
Neonatal venoarterial(VA) extracorporeal lung assist(ECLA) drains venous blood from the right atrium via the right internal jugular vein and perfuses oxygenated blood to the aortic arch via the right common carotid artery. Though VA ECLA supports cardiac function, it is not free from neurologic complications due to ligation of the carotid artery. Venovenous(VV) bypass is used early for acute respiratory failure. To reduce the number of veins ligated, a double lumen tube was developed. VV ECLA using the double lumen tube was tried on eight hypoxic dogs at F1O2 0.15. Control values of hemodynamics and blood gases were obtained while the 0.8 m kolobow lung ventilated with nitrogen gas. We measured the same parameters while ventilating the oxygenator with oxygen(ECLA on). Mean arterial pressure and mean pulmonary arterial pressure were decreased significantly during ECLA on. Bypass flow rate was 1042+/-72ml/min and bypass ratio(bypass flow rate cardiac output X100) was 40+/-15%. Arterial oxygen tension was increased from 52+/-14mmHg to 79+/-23mmHg during ECLA on, whose saturation was 94+/-2%. Venous drainage was limited with a double lumen tube, but it can be used clinically for moderate hypoxemia with ease.
Animals
;
Anoxia
;
Aorta, Thoracic
;
Arterial Pressure
;
Cardiac Output
;
Carotid Arteries
;
Carotid Artery, Common
;
Dogs*
;
Drainage
;
Gases
;
Heart Atria
;
Hemodynamics
;
Jugular Veins
;
Ligation
;
Lung*
;
Nitrogen
;
Oxygen*
;
Oxygenators
;
Respiratory Insufficiency
;
Veins
10.Factors Influencing Mortality in Geriatric Trauma.
Jong Kun KIM ; Michael Sung Pil CHOE ; Jeong Heon LEE ; Jung Bae PARK ; Kang Suk SEO ; Young Kook YUN
Journal of the Korean Society of Emergency Medicine 1999;10(3):421-430
BACKGROUND: The goal of this study is to identify the factors that predict mortality in elderly trauma patients. METHOD: We reviewed retrospectively the medical record of 144 cases of geriatric trauma admitted to Kyungpook National University Hospital firm January 1998 to December 1998. We evaluated the general characteristics, mechanisms of injury, Revised Trauma Score(RTS), Injury Severity Score(ISS), Probability of survival(Ps) by TRISS(Trauma and Injury Severity Score) method, amount of blood transfused, preexisting disease, complications, length of stay, and mortality. RESULTS: 1. The mean age was 75.39+/-7.89 years old, and male to female ratio was 0.89 : 1. 2. The mechanisms of injury were primarily frills(56.3%) followed by bicycle or motorcycle(13.9%), and pedestrian injuries(13.2%) and motor vehicle accidents(6.9%). 3. The mean Glasgow Coma Scale(GCS), RTS and ISS ate 13.3+/-3.5, 7.2+/-1.4 and 14.2 +/-11.6 respectively. 4. The actual mortality rate was 18.1% (26/144). But by TRISS method, predicted mortality rate was 9.3%(12.5/144), excess mortality rate was 108% and Z score was 3.99 indicating that actual number of death exceed predicted number of death. 5. Between the survivors and nonsurvivors, the insults were significantly different as follows ; systolic blood pressure(141.9+/-28.3 vs. 116.8+/-48.7 mmHg), GCS(14.3+/-2.0 vs. 9.0 +/-5.1), RTS(7.8+/-0.7 vs 5.4+/-2.3), ISS(11.3+/-5.6 vs 27.2+/-20.2), Ps by TRISS(0.97+/-0.06 vs 0.65+/-0.37), preexisting diseases(50.8 vs 69.8%). CONCLUSION: Geriatric patients are more likely to die after trauma than other age groups. The cause of higher actual mortality rate compared to predicted mortality rate was considered as the higher incidence of delayed death due to sepsis or multiple organ failure. In order to reduce the mortality, even with relatively stable initial vile sign, invasive hemodynamic monitoring and intensive treatment are recommended and also, prevention and treatment of nosocomial infection are very important.
Aged
;
Coma
;
Cross Infection
;
Female
;
Gyeongsangbuk-do
;
Hemodynamics
;
Humans
;
Incidence
;
Length of Stay
;
Male
;
Medical Records
;
Mortality*
;
Motor Vehicles
;
Multiple Organ Failure
;
Preexisting Condition Coverage
;
Retrospective Studies
;
Sepsis
;
Survivors