No abstract available.

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Benzodiazepines*

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Asian Continental Ancestry Group* ; Brain* ; Humans

No abstract available.
Asian Continental Ancestry Group* ; Brain* ; Humans

No abstract available.
Depression* ; Humans

No abstract available.
Defense Mechanisms*

Hermann Hesse's personal life (1877–1962) is characterized by traumatization caused by suppressive pietistic discipline of his parents during his youth, and depression in his middle age accompanied by psychoanalysis treatment. At the age of 15, he was admitted to mental institutions due to defiant behavior. With this traumatic experience, his psychosexual development seemed inhibited during his adolescence. At age 39, depression developed precipitated by the death of his father. Hesse had received Jungian psychoanalysis from Dr. Lang and Dr. Jung over a 10-year period. However, psychoanalysis could not prevent the recurrence of depression. His appreciation of psychoanalysis became critical. Meanwhile, Hesse announced that he had been a Protestant Christian. In his 50s, he began to create new novels which, beyond polarity based on Jungian psychoanalysis, described the journey toward a greater harmonious and spiritual oneness. Pietism was at one time the reason of his pain, but became life-long support for Hesse's spiritual maturity. He was diagnosed with type II bipolar disorder. The main dynamic factors are thought to be ambivalence, feelings of guilt regarding his aggression toward his parents, and sexual conflict. His coping mechanisms seemed to include pietistic self-control, avoidance, scholarship and creation of literature. By writing the autobiographical Bildungsromans, Hesse tried not only to master his own personal problems but to enlighten readers. However, it seemed that he could not overcome the feelings of guilt associated with leaving his father.
Adolescent ; Aggression ; Bipolar Disorder ; Depression ; Fathers ; Fellowships and Scholarships ; Guilt ; Hospitals, Psychiatric ; Humans ; Middle Aged ; Parents ; Protestantism ; Psychoanalysis ; Psychosexual Development ; Recurrence ; Self-Control ; Writing

The authors report a case of dexfromethorphan induced mood disorder with the review of literafures. The patient is a 19-year old female who had been taking dextromethorphan hydrobromide (trade name : romilar) for 14 month s to enjoy its pleasurable effects and to reduce anxiely. Acute intoxication symptoms of dextromethorphan hydrobromide were silly smiles, a euphoric feeling of floating and an optimistic mood. Tolerance developed and she had been taking 70 tablets (1050mg) ot maximum per day. Withdrawal symptoms were anxiely and its related symptoms and a craving for the drug. While taking 50 tagblets per day about 12 days prior to admission, she had developed leated and irritable mood. grandicstily and auditory hallucinations. These symptoms continued despite discontinuation of the drug after admission. the degree of elated and irritable patient's mood was prominent. flight of ideas was not so severe. However, there was prominent grandiosity and auditory hallucinations. She was treated with haloperidol and lithium and then showed gradual remission in 3weeks. If would necessary to explore any drug abuse history in psychiatric patients who are in their teens.
Adolescent ; Dextromethorphan* ; Female ; Hallucinations ; Haloperidol ; Humans ; Irritable Mood ; Lithium ; Mood Disorders* ; Substance Withdrawal Syndrome ; Substance-Related Disorders ; Tablets ; Young Adult

OBJECTIVES: Contemporary empirical studies have suggested high rates of comorbid attention-deficit hyperactivity disorder(ADHD) or obsessive compulsive disorder(OCD) in children with tic disorders. Not infrequently, ADHD or OCD is as source of greater impairment than are the tic symptoms. The studies in the pathophysiology of tic disorder have implicated abnormalities of dopamine, serotonin and norepinephrine. The studies in pathophysiology of ADHD or OCD also have implicated abnormalities of dopamine, serotonin and norepinephrine. This study was purposed to examine the differences in tic severities and in the levels of plasma homovanillic acid(HVA) and 5-hydroxyin-doleacetic acid(5-HIAA) according to the presence of comorbid ADHD or OCD in patients with chronic tic disorders. METHODS: In fifty chronic tic patients, OCD or ADHD was also diagnosed. And then tic symptoms, obsessive-compulsive symptoms, and attention-deficit hyperactive symptoms were assessed using Yale global tic severity scale(YGTSS), Leyton obsessional inventory-child version(LOI-CV), and Conners parent rating scale. The plasma HVA and 5-HIAA levels were measured using high performance liquid chromatography with electrochemical detection method. RESULTS: Fifty-eight percent of the patients with chronic tic disorders had comorbid ADHD or OCD. But severities of tic did not differ regardless of the presence of comorbid ADHD or OCD. There was a significant positive correlation between tic severities and plasma HVA levels but none between tic severities and plasma 5-HIAA levels. There was a significant inverse correlation between resistance and interference scores and plasma 5-HIAA levels. Plasma HVA levels showed significant positive correlations with plasma 5-HIAA levels. CONCLUSION: These results showed that tic severities didn't vary according to the presence of comorbidities, and that tic severities were correlated with plasma HVA levels, not with plasma 5-HIAA levels. These results suggested that the pathophysiology of chronic tic disorder was strongly correlated with abnormalities of dopaminergic system.
Child ; Chromatography, Liquid ; Comorbidity* ; Dopamine ; Homovanillic Acid* ; Humans ; Hydroxyindoleacetic Acid ; Norepinephrine ; Obsessive Behavior ; Obsessive-Compulsive Disorder ; Parents ; Plasma* ; Serotonin ; Tic Disorders* ; Tics*