No abstract available.
Pylorus*

No abstract available.
Colon*

PURPOSE: To analyze the causes and the clinical results of treatment for the nonunion of femur shaft fractures that occurred after interlocking intramedullary nail fixation. MATERIALS AND METHODS: We reviewed 19 cases of aseptic nonunion of femur shaft fracture in 174 patients after interlocking IM nailing from March 1999 to February 2004 and followed up for more than one year. First we investigated the factors causing nonunion. For operative options, two methods about exchange nailing and exchange nailing with bone graft were performed. Finally clinical results were analyzed with bone union rate by treatment methods and compared with the nonunion factors statistically. RESULTS: According to the causes and types of nonunion, we performed larger IM nail change in 10 cases and IM nail change with bone graft in 9 cases. Bone union was achieved in all cases. Average bone union period were 18.5 weeks in exchange group and 16.1 weeks in exchange with bone graft group. There are significant difference between treatment methods statistically (p<0.05). Compared with the nonunion factors, initial open fracture and smoking groups showed late union rate statistically. CONCLUSION: Based on our analysis, IM nail change is a useful method for nonunion after initial IM nailing in femoral shaft fracture, and additional bone graft that according to the radiologic pattern and stability, especially the fracture gap is also a useful option for nonunion treatment.
Femur ; Fracture Fixation, Intramedullary* ; Fractures, Open ; Humans ; Methods ; Smoke ; Smoking ; Transplants

STUDY DESIGN: A retrospective study OBJECTIVE: To analyze the complications, clinical outcome and any correlative risk factors of degenerative spinal deformity surgery in elderly patients. SUMMARY OF LITERATURE REVIEW: There is some controversy regarding the postoperative complications and the factors influencing them in the elderly patients who had undergone degenerative spinal deformity surgery. MATERIALS AND METHODS: Seventy eight patients, who underwent posterior decompression and posterolateral fusion requiring a minimum 3 level fusion for a degenerative spinal deformity associated with spinal stenosis between May, 2001 and May, 2006, were reviewed after a follow-up period of at least 1 year. This study compared the postoperative complications and clinical outcomes of patients over 65 years (group A) with patients between 50~64 years (group B). The risk factors that could influence the complications and clinical outcomes were evaluated and analyzed statistically. RESULTS: The postoperative complication rate was 53% in group A and 40% in group B without statistical significance. However, group A had a significantly higher frequency of minor complications than group B, particularly in urinary retention and postoperative delirium. There was an association between diabetes and deep wound infection as a major complication in groups A and B. Being male was a risk factor for urinary retention and longer surgery time, and abundant blood loss was significant risk factors for postoperative delirium in group A. CONCLUSION: There were no significant differences in the treatment result for degenerative spinal deformity between patients older than 65 and younger than 65. It is considered that the blood sugar should be controlled strictly before and after surgery, and appropriate management is needed for postoperative delirium and urinary retention in elderly patients.
Aged ; Blood Glucose ; Congenital Abnormalities ; Decompression ; Delirium ; Follow-Up Studies ; Humans ; Male ; Postoperative Complications ; Retrospective Studies ; Risk Factors ; Spinal Stenosis ; Treatment Outcome ; Urinary Retention ; Wound Infection

PURPOSE: To evaluate functions of the elbow joint according to surgical approach, time to exercise, and type of fracture after surgical treatment for the intra-articular comminuted fracture of the distal humerus. MATERIALS AND METHODS: 27 patients with the intra-articular comminuted fractures of the distal humerus underwent surgery from March, 2000 to January, 2007. We investigated the surgical approach, time for union, time to exercise and age. We also evaluated postoperative functions of the elbow joint according to the flexion contracture, the range of motion and the Mayo elbow performance score. RESULTS: The average follow-up period was 37 months and the average time for union was 14 weeks. The average range of flexion was 115 degrees, the average flexion contracture was 10 degrees, and the Mayo elbow performance score with average value of 85 point showed good clinical results. There were no statistically significant differences in functions of the elbow joint according to the operative method and age. However, patients with early postoperative exercise within 6 days showed statistically better outcomes than patients with postoperative exercise after 7 days. Type C1, 2 fractures showed statistically better results than the type C3 fracture. CONCLUSION: Stable fixation and early exercise are required to prevent postoperative complications and restore functions of the elbow joint with an intra-articular comminuted fracture of the distal humerus.
Contracture ; Elbow ; Elbow Joint ; Follow-Up Studies ; Fractures, Comminuted ; Humans ; Humerus ; Intra-Articular Fractures ; Postoperative Complications ; Range of Motion, Articular

Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease in South Korea with clinical features similar to those of scrub typhus. Infected patients with these two diseases usually visited the emergency department (ED) complaining of fever that was not responsive to treatment in a local clinic. Aggressive management of SFTS is required in order to prevent rapid progression and human-to-human transmission, thus rapid and accurate differential diagnosis of the two diseases in the ED is important. We reported three laboratory confirmed cases of SFTS during 2013-2014 in a single center, with fever, skin lesions, and history of outdoor activities in order to help in differential diagnosis between SFTS and scrub typhus in the ED.
Communicable Diseases, Emerging ; Diagnosis, Differential ; Emergency Service, Hospital ; Fever* ; Humans ; Korea ; Scrub Typhus* ; Skin ; Thrombocytopenia*

STUDY DESIGN: To determine the capability to predict the clinical manifestations and treatment outcomes of traumatic cervicothoracic cord injury patients based on MR images. OBJECTIVE: To determine the relationship between the differences in MR patterns and signal areas according to Maravilla and Cohen's classification and the PACS system compared with the Frankel classification, in patients that demonstrated neurologic improvement within 1 year. SUMMARY OF LITERATURE REVIEW: MR is the first imaging modality that directly visualizes the extent of spinal cord derangement, and thus, it has the potential to provide an accurate diagnosis of an injury and to determine the prognosis. MATERIALS AND METHODS: MR images were evaluated within 3 days of trauma in 36 spinal cord injury patients. The clinical follow-up period was more than 1 year. Quantitative analysis of spinal cord lesions was performed according to the PACS system. RESULTS: According to Maravilla and Cohen's classification, 36 cases were classified as follows: 8 cases of type I, 10 cases of type II, 9 cases of type III and 9 cases of type IV. There was 1 case of type I, 8 cases of type II, 5 cases of type III, and no cases of type IV, who demonstrated neurologic improvements of more than 1 grade in the Frankel classification. An analysis of the signal areas according to the PACS system demonstrated no cases of areas greater than 100 mm2, 5 cases of areas between 50 to 100 mm2, and 9 cases of areas less than 50 mm2 who demonstrated neurologic improvement. CONCLUSION: Classification according to the differences between MR imaging and MRI signal areas in patients with spinal cord injuries demonstrated the indicators of neurologic improvement; therefore, we MR imaging can be utilized as a prognostic factor in cases of spinal cord injuries.
Classification ; Diagnosis ; Follow-Up Studies ; Humans ; Magnetic Resonance Imaging ; Prognosis* ; Spinal Cord Injuries* ; Spinal Cord* ; Treatment Outcome*

STUDY DESIGN: A retrospective study. OBJECTIVES: To analyze the causes and treatment outcomes of reoperation after a lumbar discectomy. SUMMARY OF LITERATURE REVIEW: The major causes of reoperation after a lumbar disc surgery is recurrent disc herniation. Satisfactory outcomes can be obtained with reoperation for patients still requiring treatment. MATERIALS AND METHODS: Fifty two patients, who had undergone reoperations after lumbar discectomies with a minimum followup period of one year, were reviewed. The causes of the reoperation were analyzed according to the physical examination and conventional radiographic evaluation. The surgical outcome was assessed using the JOA score and Kirkaldy-Willis criteria, and the recovery rate was calculated according to the JOA score. Statistical analysis was carried out to evaluate the factors that might influence the outcome of reoperation. RESULTS: The causes of reoperation after lumbar disc surgery included 46 cases of recurrent disc herniation, each two cases of the wrong level, spinal canal stenosis and lumbar instability. The average JOA score increased from 11 to 24, and the average recovery rate was approximately 72%. According to the Kirkaldy-Willis criteria, the results were excellent and good in approximately 85% of cases. Statistical analysis revealed that the factors associated with a successful outcome were a single previous surgical procedure (p.0.02), a preoperative JOA score over 10 points (p.0.01), and a pain-free interval of more than 12 months after the previous operation(p.0.01). CONCLUSION: The treatment outcomes of reoperative lumbar disc herniation were satisfactory. Factors, such as the low number of prior procedures, high preoperative JOA score, and long pain-free interval after a previous operation, can lead to a successful treatment outcome of reoperation.
Constriction, Pathologic ; Diskectomy ; Follow-Up Studies ; Humans ; Physical Examination ; Reoperation ; Retrospective Studies ; Spinal Canal ; Treatment Outcome*

OBJECTIVES: This study was designed to investigate the association between the silent mutation, 102T/C and the substitution of histidine by tyrosine at position 452, 452His/Tyr polymorphism of the 5HT2A receptor gene and schizophrenia in korean population. METHOD: 102T/C and 452His/Tyr polymorphism of the 5-HT2A receptor gene was typed with PCR in 93 patients with schizophrenia and 93 healthy controls. RESULTS: 1) Genotype of 102T/T, 102T/C, 102C/C were 37(40%), 34(36%), and 22(24%), res-pectively in the patients with schizophrenia. Genotype of 102T/T, 102T/C, 102C/C were 31(33%), 41(44%), and 21(23%), respectively in the controls, Allele frequencies of 102T in the patients with schizophrena was 0.58 and that in the controls was 0.55. Allele frequencies of 102C in the patients with schizophrena was 0.42 and that in controls was 0.45. There were no differencies in genotype and allele frequency of 102T/C between the patients with schizophrenia and the controls. 2) 452His/Tyr polymorphism of the 5-HT2A receptor gene was not founeded in the patients with schizophrenia and in the controls. CONCLUSION: These results suggest 102T/C and 452His/Tyr polymorphisms of the 5-HT2A receptor gene are not causally related to the development of schizophrenia in Korean population.
Gene Frequency ; Genotype ; Histidine ; Humans ; Polymerase Chain Reaction ; Receptor, Serotonin, 5-HT2A* ; Schizophrenia* ; Tyrosine

STUDY DESIGN: This is a retrospective study. OBJECTIVE: We wanted to analyze the treatment outcome and the risk factors for adjacent segment disease after lumbar fusion. SUMMARY OF LITERATURE REVIEW: Biomechanical alterations likely play a primary role in causing adjacent segment disease. Radiographically apparent, asymptomatic adjacent segment disease is common after lumbar fusion, but this does not correlate with the functional outcomes. MATERIALS AND METHODS: We reviewed 544 patients who underwent lumbar fusion at a minimum of 5-year follow-up between March 1993 and August 2006. Risk factors analysis was performed for 48 of 544 patients with adjacent segment disease and who were needed a second operation, and the treatment outcomes were assessed for 46 patients with a minimum 1-year follow-up after the second operation. The average interval to the second operation was 4.5 years, and the average follow-up after the second operation was 34.5 months. The treatment outcome was assessed by using the modified Brodsky criteria and the reoperation rate was assessed in relation to several risk factors. RESULTS: Excellent and good operative results were obtained in 29 cases (63%) and bony fusion was achieved in 41 cases (89%). Of the risk factors we examined, multi-level fusion, a high grade of initial radiographic degeneration, the loss of physiologic lumbar lordosis and the involvement of degenerative scoliosis were associated with a high reoperation rate, with statistical significance. Age, gender, the initial diagnosis, the upper placement of the proximal screws and the extent to the sacrum were not correlated with the reoperation rate. CONCLUSION: The treatment outcome was relatively satisfactory; however, the factors influencing the treatment outcome of the second operation still need to be considered. The fusion level, the initial radiographic degeneration, the preservation of lumbar lordosis and the involvement of degenerative scoliosis are considered to be risk factors for the failure of lumbar fusion.
Animals ; Follow-Up Studies ; Humans ; Lordosis ; Reoperation ; Retrospective Studies ; Risk Factors ; Sacrum ; Scoliosis ; Treatment Outcome