PURPOSE: The purpose of this radiologic study was to evaluate the geographic patterns of low-energy trochanteric fractures using multiplanar computed tomography (CT) images for application of intramedullary nailing. MATERIALS AND METHODS: In this study, 117 trochanteric fractures (stable fracture, 39 cases, unstable fractures, 78 cases) sustained from simple slip-down were assessed. The mean age was 78.4 years (range, 60-96 years). Multiplanar CT images were assessed for evaluation of geographic features of trochanteric fracture, and the fracture exit and geographic patterns were analyzed. RESULTS: The medial and lateral exit of the trochanteric fracture showed no statistical difference by age, bone density, and comorbid disease. The exit was located at an average distance of 10.2 mm (range, 1.0-22.2 mm) from the tip of the greater trochanter (GT), and the medial exit, average distance of 8.1 mm (range, 0.0-18.3 mm) from the tip of the lesser trochanter. It was also found that there was no comminution around the anteromedial cortex of the fracture, and its contact loss was from fracture deformity. CONCLUSION: Because of no comminution, the contact restoration of the anteromedial cortex resulted in correction of fracture deformity and reduction. Trochanteric nailing by GT tip could be fixed through the proximal fragment of the fracture because the lateral exit is placed at an average distance of 10.2 mm from the GT tip.
Bone Density ; Congenital Abnormalities ; Femur* ; Fracture Fixation, Intramedullary ; Hip Fractures

Intracavernous self-injection of vasoactive agents for erectile dysfunction has been widely used in recent years due to its effectiveness and low rate of complications. Intracorporeal needle breakage during intracavernous self-injection represents an unusual complication. We report a case of intracorporeal needle breakage during self-injection of prostaglandin E1 in a 61-year-old man.
Alprostadil ; Erectile Dysfunction ; Humans ; Male ; Middle Aged ; Needles*

Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease in South Korea with clinical features similar to those of scrub typhus. Infected patients with these two diseases usually visited the emergency department (ED) complaining of fever that was not responsive to treatment in a local clinic. Aggressive management of SFTS is required in order to prevent rapid progression and human-to-human transmission, thus rapid and accurate differential diagnosis of the two diseases in the ED is important. We reported three laboratory confirmed cases of SFTS during 2013-2014 in a single center, with fever, skin lesions, and history of outdoor activities in order to help in differential diagnosis between SFTS and scrub typhus in the ED.
Communicable Diseases, Emerging ; Diagnosis, Differential ; Emergency Service, Hospital ; Fever* ; Humans ; Korea ; Scrub Typhus* ; Skin ; Thrombocytopenia*

The effects of chimeric monoclonal antibodies (cMAbs), prostaglandin E, (PGE,), and indomethacin (INDO) on antibody-dependent cellular cytotoxicity (ADCC) against human squamous cell carcinoma of head and neck (SCCHN) cell line were examined. Using the PCI-50 SCCHN cell line as target and normal human peripheral blood mononuclear cells as effector, ADCC was enhanced by the treatment of cMAbs (1.25 p,g/ml), but was inhibited by exogenous PGE (5 X 10' M). The effects of cMAb and PGE were dose-dependent. Maximal suppression of activity occured when PGE was present during the entire 4-hr 'Cr-release assay period, whereas pretreatment of effector cells with PGE had minimal inhibitory effect after washing. These results indicate that decreased ADCC seen with SCCHN targets treated with PGE is related to post-binding events, such as binding of effector and target cells. Pre-treatment of effector cells with INDO (1 ug/ml) resulted in restoration of NK activity which was inhibited by PGE. Our in vitro results suggest that INDO can increase tumor cell killing by the reversal of the suppression for many imrnune functions by PGE.
Antibodies, Monoclonal ; Antibody-Dependent Cell Cytotoxicity ; Carcinoma, Squamous Cell* ; Cell Line ; Head* ; Homicide ; Humans* ; Indomethacin ; Neck* ; Prostaglandins E

Granulocytic sarcoma is a rare extramedullary tumor composed of myeloid progenitor cells. Primary involvement of the biliary tract without evidence of leukemia is exceedingly rare. Here, we report an isolated biliary granulocytic sarcoma in a 30-yr-old man who presented with jaundice, fever, and chill without any evidence of leukemia. However, five months after the diagnosis, he developed acute myelogenous leukemia with multilineage dysplasia and chromosomal abnormality. A rare possibility of biliary granulocytic sarcoma should be considered as a differential diagnosis in patients with obstructive jaundice. A histologic evaluation by aggressive diagnostic intervention is important and may improve prognosis.
Tomography, X-Ray Computed ; Sarcoma, Granulocytic/*complications/*pathology ; Prognosis ; Male ; Leukemia, Myelocytic, Acute/*diagnosis/*pathology ; Karyotyping ; Humans ; Cell Lineage ; Bile Ducts/metabolism/pathology ; Bile Duct Neoplasms/*complications/*pathology ; Adult

OBJECTIVE: To assess whether ultrasound detection of vault hematoma can be used as a predictor of post-operative morbidity following vaginal hysterectomy. METHODS: Prospective observational study of 418 consecutive cases of vaginal hysterectomy was performed between December 2000 and May 2001. The transvaginal sonographic examination of vaginal vault in the first postoperative week (3rd or 4th day) after vaginal hysterectomy was done. Routine observation and clinical assessments were made by established management protocol: febrile morbidity, hemoglobin drop, need for transfusion, length of stay in hospital. RESULTS: Of the 418 scaned patients, 103 (24.6%) had a vault hematoma. This group was compared with the 315 patients without hematoma. Significant increases in febrile morbidity (22.3% vs 7.6%), postoperative hemoglobin drop (2.39 g/dL vs 1.58 g/dL), need for blood transfusion (10.7% vs 1.3%) and length of hospital stay (8.6 days vs 6.2 days) were seen in the hematoma group. CONCLUSION: Ultrasound detection of vault hematoma following vaginal hysterectomy is a common finding associated with increased febrile morbidity, hemoglobin drop, need for blood transfusion and longer hospital stay. Transvaginal sonography may facilitate the diagnosis of posthysterectomy vault hematoma, which are not readily detected by pelvic examination.
Blood Transfusion ; Diagnosis ; Female ; Gynecological Examination ; Hematoma* ; Humans ; Hysterectomy, Vaginal* ; Length of Stay ; Observational Study ; Prospective Studies ; Ultrasonography*

Crohn's disease (CD) is a chronic immune-mediated inflammatory disorder. Treatment strategies for CD are targeted toward various components of the proinflammatory mediators and subsequent immune response. Recently, the anti-tumor necrosis factor (TNF) monoclonal antibody, infliximab has been used in patients with CD. However, uncommon and unusual infections have been reported during anti-TNF-alpha therapy and immunomodulator. Here, we report a case of pityriasis versicolor occurring in a patient with CD receiving infliximab treatment. The patient was successfully treated with topical ketoconazole.
Antibodies, Monoclonal ; Crohn Disease ; Humans ; Infliximab ; Ketoconazole ; Malassezia ; Necrosis ; Tinea Versicolor

PURPOSE: This study attempted to evaluate the feasibility and effectiveness of ureteroscopic lithotripsy under local anesthesia. MATERIALS AND METHODS: Two hundred patients(male 91; female 109) underwent ureteroscopic lithotripsy under local anesthesia; and the results evaluated. Pain perception during the local ureteroscopic procedure was compared with that of cystoscopy, using a visual analogue pain scale(semantic differential) recorded by the patient(0-no pain; 10-maximal pain). RESULTS: The overall success rate was 93%(185/200). The success rates of upper, mid and lower ureteral stones were 83(5/6), 78(14/18) and 94%(166/176), respectively. The success rates in stones less than 10mm and more than 10mm were 94 (166/176) and 86%(30/35), respectively. There were 5 cases(3%) of complications: ureteral injury(1), pyelonephritis(2) and ureteral stricture(2). Although the mean pain scale score was higher in the ureteroscopy(3.33+/-1.75) than the cystoscopy group (3.13+/-1.92), this was not statistically significant(p>0.05). Most of the patients tolerated the pain during the procedure, with only two requiring general anesthesia. The postoperative pain was also tolerable in most patients, with only 8(4%) requiring more analgesics after the procedure. CONCLUSIONS: The effectiveness and morbidity of ureteroscopic lithotripsy, under local anesthesia, was found to be comparable with many other previous reports, and most of the patients could tolerate the pain of the procedure. Therefore, ureteroscopic lithotripsy can be performed effectively and safely under local anesthesia.
Analgesics ; Anesthesia ; Anesthesia, General ; Anesthesia, Local* ; Calculi ; Cystoscopy ; Female ; Humans ; Lithotripsy* ; Pain Perception ; Pain, Postoperative ; Ureter ; Ureteroscopy

Our objective is to describe the characteristic CT findings of gastrointestinal (GI) tract perforations at various levels of the gastrointestinal system. It is beneficial to localize the perforation site as well as to diagnose the presence of bowel perforation for planning the correct surgery. CT has been established as the most valuable imaging technique for identifying the presence, site and cause of the GI tract perforation. The amount and location of extraluminal free air usually differ among various perforation sites. Further, CT findings such as discontinuity of the bowel wall and concentrated free air bubbles in close proximity to the bowel wall can help predict the perforation site. Multidetector CT with the multiplanar reformation images has improved the accuracy of CT for predicting the perforation sites.
Gastrointestinal Tract/*radiography ; Humans ; Intestinal Perforation/etiology/*radiography ; Peptic Ulcer Perforation/*radiography ; Tomography, X-Ray Computed

PURPOSE: To evaluate functional results and complications after minimally invasive plate osteosynthesis through an anterior approach for distal tibial fractures, including pilon fracture. MATERIALS AND METHODS: Between March 2007 and December 2008, thirteen patients with fractures of the distal tibia were treated with minimally invasive plate osteosynthesis through an anterior approach, and were followed for a mean of 16.2 months (range, 12-30 months). Fractures according to the AO/OTA classification were six 43A, four 43B and three 43C. We analyzed functional results by bone union, postoperative complications, and the Olerud and Molander ankle scoring system. RESULTS: All fractures were united after a mean of 15.7 weeks (range, 12 to 24 weeks) except one case. There were 2 cases of superficial wound infection, one case of fibular shortening and metal failure, and two cases of tibialis anterior tendon adhesion. The average functional score was 79 points (range, 35-95 points) and results were four excellent, six good and three fair. CONCLUSION: Minimally invasive plate osteosynthesis through an anterior approach may be used for distal tibial fracture with medial soft tissue injury, and has an advantage in that the metaphyseal and distal articular fracture are fixed at the same time through a single incision However, it should be approached with caution because of the risk of complications due to the anterior approach, such as iatrogenic injury of the tibialis anterior tendon.
Animals ; Ankle ; Humans ; Imidazoles ; Nitro Compounds ; Postoperative Complications ; Soft Tissue Injuries ; Tendons ; Tibia ; Tibial Fractures ; Wound Infection