There have been reported cases that the Krukenberg Tumor had been primary ovarian carcinoma. But the Krukenberg Tumor is generally known as one special type of metastatic ovarian carcinoma, which histologically consists of nest of mucin filled signet-ring cells in a cellular, nonneoplastic stroma. The most common gastrointestinal tract origin for Krukenberg tumor is the stomach, and the next frequent is the large intestine. Generally the Krukenberg tumor is difficult to diagnose and treat until somewhat enlarging its size. We experienced a case of the Krukenberg tumor on the remained ovary after the previous unilateral adnexectomy, which was metastasized from adenocarcinoma of stomach. We present this case with a brief review of literature.
Adenocarcinoma ; Female ; Gastrointestinal Tract ; Intestine, Large ; Krukenberg Tumor* ; Mucins ; Ovary ; Stomach

No abstract available.
Animals ; Blastocyst* ; Embryonic Structures* ; Mice*

Femoral fracture, dislocation of the hip, or tasumatic amputation of the ipsilateral lower extremity is a rare injury. There has been only a few reports describing their managements. All amputated limbs are vulnerable to fracture, which occur frequently around the hip. Conservative treatments are not always adequate for the managements of fracture and dislocation of the hip and operative procedures are needed in almost patients. Among various operative measures, prosthetic replacement surgery may be indicated in cases of non-united fracture of the femoral neck, avascular necrosis of the femoral head, pathological fracture, or osteoporosis. We performed two cases of total hip replacement for the non-united fracture of the femoral neck(case 1) and the avascular necrosis of the femoral head(case 2) in the ipsilateral lower limb amputees, each. The early results were known to be very satisfactory postoperatively. The first patient was followed for 17 months and the second patient for 22 months. 1. P.C.A. femoral stems and acetabular cups were used without cement in both cases. A operative time was 2 hours and 22 minutes in the first case, 1 hour 45 minutes. in the second case. 2. There were no significant intraoperative or postoperative complications. 3. The functions of each hip were evaluated postoperatively by the method of Jesse and showed satisfactory results. 4. During the follow-up period, roentgenogram showed no significant bony changes around the femoral stems and acetabular cups. 5. The prosthetic replacement is also valuable for the treatment of the fracture-dislocation of the hip in the lower limb amputee.
Acetabulum ; Amputation ; Amputees ; Arthroplasty, Replacement, Hip ; Dislocations ; Extremities ; Femoral Fractures ; Femur Neck ; Follow-Up Studies ; Fractures, Spontaneous ; Head ; Hip ; Humans ; Lower Extremity ; Methods ; Necrosis ; Operative Time ; Osteoporosis ; Postoperative Complications ; Surgical Procedures, Operative

This is a follow-up study of 88 cases of cementless total hip replacement in 77 patients(59 males and 18 female), using AML, PCA and HGP prostheses, performed at the Department of Orthopaedic Surgery, Yonsei University Wonju College of Medicine, between September 1984 and December 1987. The follow-up period ranged from 18 to 56 months, the average being 34 months. The youngest patient was 21 and the oldest one was 79, the average being 47 years. The results were as follows:1. The average of Harris hip score was 89.7 points(Preop, 55.4 pints) at one year for 77 patients and 91.4 points at two years for 68 patients. 2. Radiographic analysis. a. Radiodense line:10 cases(11.4%) around the acetabular cup. 20 cases(22.7%) around the femoral stem. b. Calcar resorption:4 cases with AML stem(4/30), 2 cases with HGP stem(2/7). c. Subsidence:5 cases in PCA group(5/51).d. Radiological loosening:1 cases in PCA stem(1/51). 3. Intraoperative complications a. Femur neck fracture:15 cases(17%);5 cases in PCA group(5/51), 8 cases in AML group (8/31), and 2 cases in HGP group(2/7). b. Lateral collateral ligament tear:One case in PCA prosthesis(1/51). 4. Postoperative complications a. Prosthetic joint dislocation occured in 3 cases:1 case, closed reduction after tight adductor release:2 cases, cup reinsertion due to poor cup position. 5. Heterotopic ossification developed in 5 cases(5.7%) without significant loss of ROM. 6. Postoperative infection developed in 2 cases(2.3%):One superficial and the other deep. All were treated successfully with systemic antibiotics after irrigation and debridement.
Acetabulum ; Anti-Bacterial Agents ; Arthroplasty, Replacement, Hip ; Debridement ; Dislocations ; Femur Neck ; Follow-Up Studies ; Gangwon-do ; Hip ; Humans ; Intraoperative Complications ; Joints ; Lateral Ligament, Ankle ; Male ; Ossification, Heterotopic ; Passive Cutaneous Anaphylaxis ; Postoperative Complications ; Prostheses and Implants

No abstract available.
Female ; Humans

BACKGROUND: Several methods have been developed to measure skin thickness, including the use of the radiography, micrometer screw gauge, Harpenden's caliper, and ultrasound, but there are no reports to measure skin thickness using computed tomography. OBJECTIVE: We measured skin thickness on the CT films retrospectively. This study was to investigaste variations of skin thickness by age, gender, and different sites. METHODS: Skin thickness was measured on the CT films of 562 patients, including 357 males and 205 females who had undergone brain, chest, and abdominal CT in our hospital. Patients with endocrinologic, malignant, or collagen disease and those on antimetabolite or steroid therapy were excluded. Comparisons of histometric and computed tomographic methods weremade in 5 skin tumors and 1 localized lipodystrophy. Results: 1. The measurements of the skin thickness(mean) in examined sites varied from 0.84 to 3.07 milimeters : the posterior part at the level of the chest(aortic arch level) was the thickest and the anterior part at the level of the forehead(aortic arch level) was the thickest and the anterior part at the level of the forehead(frontal sinus level) was the thinnest. 2. Skin thickness in males wal generally thicker than in females : the anterior and lateral part at the level of the forehead(P<0.0001), the posterior part at the level of the bladder(P<0.2) were thicker in males than in females. 3. In each gender, the thickness of the skin increased with age of 40 or 60, and then decreased with age at every level. 4. Skin on posterior parts of the body was thicker than on other parts. 5. Unlike other levels, skin was thicker on the lateral parts than on the anterior parts at the levels of the forehead and bladder. 6. The measured skin thickness in about 7% greater in formalin fixed tissues than on CT films. CONCLUSION; Computed tomographic measurement of the skin thickness in a reliable method in the aquisition of normal values and their individual variations during cutaneous aging. Moreover, this method is useful in evaluating skin tumors and monitoring the response to therapy of inflammatory conditions.
Aging ; Brain ; Collagen Diseases ; Female ; Forehead ; Formaldehyde ; Humans ; Lipodystrophy ; Male ; Radiography ; Reference Values ; Retrospective Studies ; Skin* ; Thorax ; Tomography, X-Ray Computed ; Ultrasonography ; Urinary Bladder

BACKGROUND: One of the most, probable pathogenesis of vitiliga is autoimmune. Systemic cor tico st,eroids suppress immunity and may arrest the progression of vitiligo and lead to repigmentation. OBJECTIVE: We have assessed the clinical effect of a oral small oral dose of corticosteroid to minimize side effects in vitiligo patients. METHODS: Thirty four patients(9;male, 25;female) with vitiligo were evaluated in this study. The patients took 7.5mg-20mg prednisolone initially for 2 months and then the dosage was tapered to half of the initial dosiat the 3rd month and half of dose of 3rd month for the last 4th month. We compared the effcct of treatment of vitiligo before and aft.er the study by photographs. and side efferts were issessed at. 1, 2, 3 and 4 month. RESULTS: The arrest of the progression of vitiligo was noticed in 79% of patients and repigmentation was noticed in 59% of patients which is statistically significant. The effect, of treatment according to extent, duiation, type, and site of vitiligo were not statistically significant. The side effects of treatment were minimal and did not affect the course of treatment. CONCLUSION: Small doses of iral corticosteroids are effective without any significant side effects in preventing progression and loiiduce repigmentation of active spreading vitiligo and generalized type of vitiligo that is difficult to treat with topical corticosteroids.
Adrenal Cortex Hormones* ; Humans ; Prednisolone ; Vitiligo*

BACKGROUNDS: An inhibitory effect of magnesium L-ascorbyl-2-phosphate (VC-PMG, a stable derivative of ascorbic acid) on melanogenesis has been described. Furthermore, glabridin in licorice is known to have inhibitory effects on melanogenesis and widely used for raw materials for depigmenting agents. OBJECTIVE: The purposes of this study are to provide objective data by measuring the visual clinical effects of VC-PMG with the colorimeter and to promote the development of de-pigmenting agents. METHODS: 20 volunteers joined the study. With an artificial UVB irradiation, eight tanned areas were made on the inner side of the forearm. During two months, each tanned area was treated with five whitening cosmetics with 3% VC-PMG and increasing concentration of licorice from 0% to 3%. Darkness degree of each area was measured weekly by the colorimeter and the visual assessment. RESULTS: For all cosmetics, whitening effect was measured by colorimeter and visual as-sessment. The cosmetic containing VC-PMG 3% and licorice 1% had more whitening effect than any other cosmetics of different concentrations. Moreover, VC-PMG 3% alone also had whitening effect in some volunteers. CONCLUSION: VC-PMG was clinically found to have whitening effect.
Ascorbic Acid* ; Darkness ; Forearm ; Glycyrrhiza ; Magnesium* ; Triacetoneamine-N-Oxyl ; Vitamins* ; Volunteers

Antibiotic therapy for acne is now considered one of the most effective regimen. Thirty years ago, oral antibiotics were introduced for acne vulgaris and topical preparations have been available by prescription for more than 15 years. Recently, clindamycin, erythromycin and tetracycline were regarded as the most effective and widely used antibiotics. Many authors reported that clindamycin was a mast effective topical antibiotic for acne vulgaris but side effects, i.e., contact dermstitis or pseudomembranous colitis were reported. The author studied the clinical effectiveness and side effects of Fabrys salution, which has been used as an antiseptic and keratolytic agents, and Fabrys solution containing chloramphenicol or clindamycin. Fifty three patients who were followed for 6 weeks were studied. They were divided into three groups: group I was treated with Fabrys solution(F solution), group II was treated with Fabrys solution containing chloramphenicol(F-c solution) and group Ill was treated with Fabrys solution containing clindamycin(F-cd solution).
Acne Vulgaris* ; Anti-Bacterial Agents* ; Chloramphenicol ; Clindamycin ; Enterocolitis, Pseudomembranous ; Erythromycin ; Humans ; Keratolytic Agents ; Prescriptions ; Tetracycline

No abstract available.
Humans ; Temporomandibular Joint Disorders* ; Temporomandibular Joint*