There have been reported cases that the Krukenberg Tumor had been primary ovarian carcinoma. But the Krukenberg Tumor is generally known as one special type of metastatic ovarian carcinoma, which histologically consists of nest of mucin filled signet-ring cells in a cellular, nonneoplastic stroma. The most common gastrointestinal tract origin for Krukenberg tumor is the stomach, and the next frequent is the large intestine. Generally the Krukenberg tumor is difficult to diagnose and treat until somewhat enlarging its size. We experienced a case of the Krukenberg tumor on the remained ovary after the previous unilateral adnexectomy, which was metastasized from adenocarcinoma of stomach. We present this case with a brief review of literature.
Adenocarcinoma ; Female ; Gastrointestinal Tract ; Intestine, Large ; Krukenberg Tumor* ; Mucins ; Ovary ; Stomach

BACKGROUND: Epidermal cysts are the most common of all cysts. OBJECTIVE: The purpose of this paper is to report the clinical and histopathologic features of epidermal cysts. METHODS: We reviewed the clinical and histopathologic features of 205 cases that were diagnosed with epidermal cysts at the department of dermatology in Anam Hospital of Korea University for 11 years, from January 1983 to December 1993. RESULTS: 1. Of the 3,400 cases of skin biopsy specimens, 205 cases were epidermal cysts(6%). There were 141 male cases (68.8%) and 64 female cases (32.2%). The ratio of male to female was 1:0.45. 2. Most patients with epidermal cysts belonged to age ranging from 20 to 59 with the highest incidence in the 3rd decade. 3. The site of predilection of the epidermal cysts were face 94(45.9%), trunk 37(18.0%), neck 23(11.2%), leg 21(10.2%), arm 19(9.3%),scalp 7(3.4%), scrotum 2(1.0%), and vagina 2(1.0%). 4. Histopathologically, 61 cases (29.3%) were ruptured. The most common cystic wall change was acanthosis followed by atrophy, hyperplasia, hypergranulosis, parakeratotis, basalioma-like change, squamous eddies, dyskeratosis. The most common cystic content was keratinous material followed by parakeratotic cells, pigment, bacterial colony, RBC, inflammatory cells, hair shaft, calcification, trichilemmal keratinization, pilomatricoma-like change. The most common stromal change was giant cells followed by fibrosis, granulation tissue formation,vessel proliferation, pigment. CONCLUSION: According to our results, which agree with those of Chung, the epidermal cysts occur as a disease particular to young men, especially on the face. Histopathologically, when an epidermal cyst ruptures and the contents of the cyst are released into the dermis, a considerable foreign body reaction with numerous multinucleated giant cells results.
Arm ; Atrophy ; Biopsy ; Dermatology ; Dermis ; Epidermal Cyst* ; Female ; Fibrosis ; Foreign-Body Reaction ; Giant Cells ; Granulation Tissue ; Hair ; Humans ; Hyperplasia ; Incidence ; Korea ; Leg ; Male ; Neck ; Rupture ; Scrotum ; Skin ; Vagina

No abstract available.
Intercellular Adhesion Molecule-1* ; Prurigo*

No abstract available.
Denture, Partial, Removable*

BACKGROUND: Statistical errors have been noted in a large percentage of articles appearing in medical journals. Their incidence in the Annals of Dermatology and the Korean Journal of Dermatology, however, has not been studied. OBJECTIVE: The purpose of this study was to evaluate the accuracy of statistical methods in the Annals of Dermatology and the Korean Journal of Dermatology. METHOD: Original papers using the t test in the Annals of Dermatology(AD) and in the Korean Journal of Dermatology(KJD) from January 1990 to July 1994 were analyzed for correctness of statistical methods. RESULTS: Of the 376 original papers in the period considered, 78(20.7%) presented t tests and 43(55.1%) of these also contained some errors. Of the 9 papers from the Annals of Dermatology, 4(44.4%) included at least one error. Of the 69 papers from the Korean Journal of Dermatology, 39(56.5%) included at least one error. CONCLUSION: Misuse of statistical methodology may not be uncommon in the two Korean Dermatology journals, and it would be prudent to give more attention to statistical methodology.
Dermatology* ; Incidence ; Methods

Ants(Family Formicidae) are very successful organisms occuring in trernendous numbers worldwide in terrestrial habitats. All ant species may bite, and on species sting. 48 species in 26 genus have been reported in Korea, but only systemic reaction induced by the anti Brachyponera chinersis, has been reported in the Korea terature. A 48 year old man was stung on the neck, abdomen, and dorsum of the hand by flying stinging ants. He experienced moderate pain, burning and itching sensation. Clinical course and histopathologic findings of the lesions caused by the stinging ant was observed without specific treatment. The stinging ants collected from t,he patient.s skin and his house were identified as Euponera chosensis belonging to Subfamily Ponerinae. To the best of our know ledge, this is the first clinical repor of the insect sting by Euponera chosensis in the Korean literature.
Abdomen ; Ants ; Bites and Stings ; Burns ; Diptera ; Ecosystem ; Hand ; Humans ; Insect Bites and Stings* ; Insects* ; Korea ; Middle Aged ; Neck ; Pruritus ; Sensation ; Skin

We examined a male infant with transient increase in alkaline phosphatase(ALP) activity. The 25-month-old infant was admitted to a local hospital because of pneumonia of unknown etiology. Initial laboratory investigation revealed a serum ALP of 11,260U/L, which was comparable to that of bone isoenzyme on the electrophoresis pattern, There was no evidence of hepatitis, skeletal or intestinal diseases. The hyperphosphatasemia disappeared 3 months later. We report a case of transient hyperphosphatasemia diagnosed inci- dentally in the course of management of pneumonia. (J Korean Pediatr Soc 2000;43:856-860)
Alkaline Phosphatase ; Child, Preschool ; Electrophoresis ; Hepatitis ; Humans ; Infant ; Intestinal Diseases ; Male ; Pneumonia

Becker's nevus has been known as a sudden onset of hyperpigmentation on shoulder or arm in the second decade of life with slow peripheral extension and later development of hypertrichosis. We observed two cases of typical Becker's nevus which was confirmed by characteristicclinical and histopathological findings. One was 45-year-old male who has a patch of hyperpigmentation and hypertrichosis on left upper arm at birth, the other was 2()-year-old male who developed on right shoulder after sunburn which is a salient feature by Becker's initial description.
Arm ; Burns ; Humans ; Hyperpigmentation ; Hypertrichosis ; Male ; Middle Aged ; Nevus* ; Parturition ; Shoulder ; Sunburn

Fibrous papule of the face occurs nearly always as a solitary lesion on the face, especially on the nose. The lesion which appears as a dome shaped papule, is skin colored, pigmented or red, We present herein three cases of fibrous papule of the face, which developed on the ala nasi of 45-year-old man, and 49-year-old woman, and on the nostrile of 25-year-old woman. Histopathologic findings showed dermal angiofibrotic changes in two cases. In one of the two cases, there were atypical cells with large irregular nucleus and a few multinucleated giant cells interspersed in the edematous dermis, and there was distinct perifollicular fibrosis in the other case.
Adult ; Dermis ; Female ; Fibrosis ; Giant Cells ; Humans ; Middle Aged ; Nose ; Skin

Vitamin A and its metabolite, retinoic acid, have been recommended for the treatment of psoriasis, ichthyosis, acne vulgaris and Darier's disease which resulted from abaormal regulatory function of keratinocytes. In recent years retinoic acid analogs (retinoids) have been synthesized and shown to be more potent and less toxic than retinoic acid. Since these drugs are therapeutically effective for skin diseases, only with longterm adminiatration of large doses, their toxicities must be seriously considered. The liver is the main site for both storage and excretion of vitamin A and ita derivatives, which may produce injury to the liver and other organs as a result of excess of lysosomal enzyme control. Fatty vacuoles, infiltration of inflammatory cells, focal necrosis, increase in lysosomal enzymes, distension of the RER, decrease in the ribosomes, swelling of the mitochondria, and proliferation of the SER within the hepatocytes have been observed in livers of vitamin A- as well as retinoic acid-treated rats. Its excess may also cause mucous metaplasia of secretory cells of the pancreas. (countinued...)
Acne Vulgaris ; Amphotericin B* ; Animals ; Darier Disease ; Hepatocytes ; Ichthyosis ; Keratinocytes ; Liver ; Metaplasia ; Mitochondria ; Necrosis ; Pancreas ; Psoriasis ; Rats ; Ribosomes ; Skin Diseases ; Tretinoin ; Vacuoles ; Vitamin A ; Vitamins