The eosinophil is the major cell responsible for the inflammatory reaction in bronchial asthma. Secretion of granular components is probably of considerable importance for the inflammatory effects of the eosinophils. Eosinophil cationic protein (ECP) is the one of the secretory components of the eosinophil granule and-is considered as an activation marker of eosinophil count, serum concentration of ECP and serum IgE were studied in normal, symptomatic and asymptomatic asthmatic children. In symptomatic asthma, peak expiratory flow rate (PEFR) was studied and methacholine challenge test was done in asymptomatic asthma in addition. Blood eosinophil count and serum ECP in asthma were significantly raised compared with those of the normal children. And the level of serum ECP in symptomatic asthma was higher than that in asymptomatic asthma. The mean % fall of PEFR was significantly correlated with serum ECP and blood eosinophil count in symptomatic asthma. In asymptomatic asthma, there was no correlations between methachloine PC20 and blood eosinophil count or methachloine PC20 and serum ECP level. Our findings show that blood eosinophil count and serum ECP levels differ not only between normal children and asthmatic children, but also between symptomatic asthma and asymptomatic asthma.
Asthma ; Child* ; Eosinophil Cationic Protein* ; Eosinophils* ; Humans ; Immunoglobulin E ; Methacholine Chloride ; Peak Expiratory Flow Rate

No abstract available.
Bone Cysts* ; Methylprednisolone*

Thirteen guinea pigs and 23 rabbits were challenged with 300 metacercariae of Clonorchis sinensis each and the recovery of adult worms and egg counts in feces were compared at 11-13 weeks post-infection in guinea pigs and at 7-9 weeks post-infection in rabbits. The recovery rate of adult worm was 23.5 percent in guinea pigs and 20.l-30.5 percent in rabbits. The mean E.P.G. of these animals in above period of infection was 106 in guinea pigs and 121 in rabbits. When one hundredth of E.P.G. was expressed as X and the number of adult worms as Y, the relationships between X and Y were as follows; Y=0.8X+10.8 in guinea pigs and Y=0.7X+6 in rabbits.
parasitology-helminth-trematoda ; Clonorchis sinensis ; guinea pig ; rabbit ; egg

No abstract available.
Female ; Germ Cells* ; Neoplasms, Germ Cell and Embryonal* ; Ovary*

Measurement of the normal pituitary gland height was performed on magnetic resonance (MR) images of 144 subjects with no known or suspected pituitary or hypothalamic diseases. Midsagittal T1 weighted images (T1WI) were used for measurement, and mean vertical height according to age and sex group was obtained. In all age groups, the pituitary height was greater in females than in meles, The group of 0-9 years in both genders showed the minimum mean pituitary height, The maximum mean height was observed in the 10-19 years age group in both genders. The height gradually decreased with increasing age after age 20 years. There was no subject with a height more than 9.0 mm in females or 8.0 mm in males. In conclusion the measurement of the normal pituitary pland height using mid sagittal MR imaging can be used for the evaluation of the pituitary gland lesions.
Female ; Humans ; Hypothalamic Diseases ; Magnetic Resonance Imaging ; Male ; Pituitary Gland* ; Sex Differentiation*

No abstract available.
Thumb*

No abstract available.
Head*

No abstract available.
Extremities* ; Neurilemmoma*

Fractures significantly involving the weight-bearing articular surface and the overlying metaphysis of the distal tibia have deserved notoriety as a severe and challenging subject of ankle injuries. It was not until 1963 that the AO group developed principles for open reduction and internal fixation of pilon fracture. But recently, limited internal fixation of the joint surface combined with external fixation may avoid the soft tissue complications associated with formal open reduction and internal fixation. We have treated 22 cases of tibial pilon fracture with biologic principle. The mean follow-up period was two years ranging from one to three years. According to the Riiedi and Allgower classification, three cases were type I, five cases were type II, and fourteen cases were type III Biologic treatment includes combination of internal and external fixation, external fixation alone, or plating was done with careful soft tissue dissection, limited stripping of fracture fragments, and indirect reduction technique. Radiographic results were assessed by Burwell and Charnley criteria. Three cases of type I, three cases of type II and seven cases of type III pilon fractures obtained good anatomic radiographic results. We also assessed the functional results by Mast and Teipner criteria. Three cases of type I, three cases of type II, six cases of type III pilon fractures obtained good functional outcome. We believed that combination of internal and external fixation provides the patient who has a markedly displaced pilon fracture and diaphyseal comminution with the best chance of good clinical result and minimal risks. As such, we believe biologic treatment is excellent for these injuries.
Ankle Injuries ; Classification ; Follow-Up Studies ; Humans ; Joints ; Tibia ; Weight-Bearing

No abstract available.
Cholesteatoma* ; Semicircular Canals* ; Temporal Bone* ; Tomography, X-Ray Computed*