No abstract available.
Lung*

To analyze the correlation between biological phenotypes of HIV-1 isolates and disease progression, we selected 9 long-term non-progressors (LTNP) and 12 rapid progressors (RP) from HIV-1 infected Korean. We isolated HIV-1 isolates by culture of PBMC of LTNP and RP with normal PBMC and measured HIV-1 p24 antigen production. The HIV-1 isolation rate from LTNP was 55.6% (5/9). And 4 HIV-1 LTNP isolates were non-syncytium inducing (NSI) phenotype and showed slow/low replication. The HIV-1 isolation rate from RP was 91.7% (l1/12) which was higher than that from LTNP. Besides 3 RP HIV-1 isolates which showed syncytium inducing (SI) phenotype, 8 RP HIV-1 isolates showed NSI phenotype in normal PBMC and MT-2 cell line. All RP HIV-1 isolates replicated more rapidly than LTNP HIV-1 isolates. Comparing the replication kinetics and syncytium forming capacity of HIV-1 isolates from LTNP and RP, we suggest that the difference of biological phenotype of HIV-1 isolates could be related with disease progression of HIV-1 infected persons.
Cell Line ; Disease Progression ; Giant Cells ; HIV-1* ; Humans ; Kinetics ; Korea* ; Phenotype

The author fractographically analyzed the cause of metal failure (the first time this procedure has been used for this metal failure) and also analyzed in clinically. In this study, I selected eight cases which have been analyzed fractographically. In all these cases, the analysis was done after treatment of metal failure of implants internally fixed to femur shaft fractures at the Department of Orthopedic Surgery, Yeung-Nam University Hospital during the six year period from May 1983 to September 1989. 1. Metal failure occurred in five dynamic-compression plates, one Jewett nail, one screw in Rowe plate, and one interlocking nail. 2. The clinical cause of metal failure was deficiency of medial buttes in five cases, incorrect position of implant in one case, and incorrect selection of implant in two cases. 3. The time interval between internal fixation and metal failure was four months in one case, between five months to twelve months in six cases, three years in one case. 4. The fractographically analytical cause of metal failure was ; first, impact failure, one case, second, fatigue failure, six cases, machining mark (stress riser), four case type: low consistent cyclic fatigue failure irregular cyclic fatigue failure third, stress corrosion crack, one case. 5. 316 L Stainless Steel has good resistance to corrosion. However, when its peculiar surface film is destroyed by fretting, it shows pitting corrosion. This is, perhaps, the main cause of metal failure. 6. It is possible that mechanical injury occurred in implants during the manufacturing of implants or that making a screw hole in the main cause of metal failure.
Corrosion ; Fatigue ; Femur* ; Orthopedics ; Stainless Steel

We report one case in which delayed enhanced computerized tomography (1.5 hr. later) contributed in detecting a dysplastic kidney with a single vaginal ectopic ureter that had been nonfunctioning on excretory urography and had not been detected by other diagnostic methods.
Kidney ; Ureter* ; Urography

Testosterone therapy in high doses produces male infertility. There are reports that atrophy of the interstitial cells and decrease in testicular size occur in the rat after treatment with testosterone, and the azoospermia which resulted from testosterone therapy could be reversed by simultaneous treatment with HCG. This study was evaluated for 45 days to clarify microscopic changes in the testis. A total of 60 male mice, 30 BALB/C strain, aged 3-4 weeks and with an average body weight of l2 g and 30 BALB/C strain, aged 3 months and with an average body weight of 20 g, were divided into 2 groups; for one group treatment with testosterone propionate only and another group fur treatment with testosterone propionate and HCG. The results of histological structure were as follows: 1. Mature group, treated with testosterone propionate (0.25mg/g B.W.) daily, reduced Leydig cell numbers and showed germinal epithelium atrophy, and inhibited spermatogenesis. 2. Mature group, treated with testosterone propionate (0.25mg/g B.W.) daily and HCG (2.5 I.U./g B.W.) every 3 days, showed normal variation of interstitial cell, germinal epithelium and spermatogenesis. 3. Immature group, treated with testosterone propionate (0.25mg/g B.W.) daily, increased in numbers of Leydig cells slightly and showed tortuous tubules and spermatogenesis. 4. Immature group, treated with testosterone propionate (0.2.mg/g B.W.) daily and HCG (2.5 I.U./g B.W.) every 3 days, showed normal variation of interstitial cell, germinal epithelium and spermatogenesis.
Animals ; Atrophy ; Azoospermia ; Body Weight ; Cell Count ; Epithelium ; Humans ; Infertility, Male ; Leydig Cells ; Male ; Mice* ; Rats ; Spermatogenesis ; Testis* ; Testosterone Propionate ; Testosterone*

No abstract available.
Amino Acid Sequence* ; HIV* ; Phenotype*

OBJECTIVE: Stent-assisted coiling on intracranial aneurysm has been considered as an effective technique and has made the complex aneurysms amenable to coiling. To achieve reconstruction of intracranial vessels with preservation of parent artery the use of stents has the greatest potential for assisted coiling. We report the results of our experiences in ruptured wide-necked intracranial aneurysms using Y-stent coiling. METHODS: From October 2003 to October 2011, 12 patients (3 men, 9 women; mean age, 62.6) harboring 12 complex ruptured aneurysms (3 middle cerebral artery, 9 basilar tip) were treated by Y-stent coiling by using self-expandable intracranial stents. Procedural complications, clinical outcome, and initial and midterm angiographic results were evaluated. The definition of broad-necked aneurysm is neck diameter over than 4 mm or an aneurysm with a neck diameter smaller than 4 mm in which the dome/neck ratio was less than 2. RESULTS: In all patients, the aneurysm was successfully occluded with no apparent procedure-related complication. There was no evidence of thromboembolic complication, arterial dissection and spasm during procedure. Follow-up studies showed stable and complete occlusion of the aneurysm in all patients with no neurologic deficits. CONCLUSION: The present study did show that the Y-stent coiling seemed to facilitate endovascular treatment of ruptured wide-necked intracranial aneurysms. More clinical data with longer follow-up are needed to establish the role of Y-stent coiling in ruptured aneurysms.
Aneurysm ; Aneurysm, Ruptured ; Arteries ; Follow-Up Studies ; Humans ; Intracranial Aneurysm ; Korea ; Male ; Middle Cerebral Artery ; Neck ; Parents ; Spasm ; Stents ; Subarachnoid Hemorrhage

Use of stent assisted coiling of intracranial aneurysms has shown a recent increase. Despite technical improvement and accumulated clinical experiences, due to insufficient study data, debate over short and long term durability and associated complication has continued. To the best of our knowledge, this case report, for the first time, demonstrates delayed self-expansion phenomenon occurring as an acute and unpredictable complication of Neuroform stent assisted coiling for treatment of a ruptured intracranial aneurysm.
Intracranial Aneurysm ; Stents

PURPOSE: To evaluate the clinical usefulness of PAP in staging and monitoring of patient with prostate cancer, we performed a comparative study with PSA, retrospectively. METHODS: We evaluated 72 patients with prostate cancer. Of these patients 11 had stage A, 6 stage B, 10 stage C, 5 stage D1 and 40 stage D2 prostate cancer. Serum PAP level was measured in all 72 patients and serum PSA level was measured concomitantly in 42 patients. RESULTS: The mean initial PAP value was 13.40+/- 7.00 U/L. But only 40 (55.6%) had elevated PAP value above 1.5U/L at presentation. Of 55 advanced cases (stage C, D), 39 (76.9%) had elevated PAP values. Of the 42 patients, who underwent longitudinal PSA assessment, the mean initial PSA value was 178.0 +/- 33.3 ng/ml. Forty (95.2%) had elevated PSA value above 4 ng/ml at presentation. Of 41 advanced cases (stage C, D1, D2), 33 (80.5%) exceeded 50 ng/ml. None of the patient had elevated PAP value with normal PSA value at presentation. Among 42 patients, who had followed with longitudinal serum PSA and PAP, progression of the disease to the bone, lung, and rectum occurred in 26 patients; in all PSA was the first indicator of progression and in none of them PAP anticipated PSA elevation. CONCLUSIONS: Although PAP value usually reflects advanced prostate cancer (70.9%), serum PSA also reflects it (80.5%). Serum PSA monitoring is superior to serum PAP monitoring in predicting disease progression. The use of PSA and PAP jointly to stage and monitor prostate cancer did not appear to enhance the clinical utility over that of PSA alone.
Acid Phosphatase* ; Disease Progression ; Humans ; Lung ; Prostate* ; Prostate-Specific Antigen* ; Prostatic Neoplasms* ; Rectum ; Retrospective Studies

PURPOSE: this study was to develop and test the structural model that explains husband and wife compatibility and family health of married middle-aged. A hypothetical model explaining husband and wife compatibility and family health based on literature reviews. There were three theoretical variables and twelve observed variables in hypothetical model. METHODS: Data collection was carried out May through July 2005. Data were collected by self-reporting questionnaires from 854 married middle-aged who lived in Seoul, Busan, Daegu, Kyungnam, Kyungpook. Collected data was analyzed using SPSS/WIN 12.0 for descriptive statistics, Pearson Correlation coefficient, and Kolmogorov-Smirnov analysis. RESULTS: LISREL program was used to find the best fit normal which assumes causal relationship among variables. This model was to be good fitting and parsimonious to measure husband and wife compatibility and family health of married middle-aged. CONCLUSION: Differentiation of self and husband and wife compatibility predicted level of family health. Therefore, a family health improvement program needs to include these two variables.
Data Collection ; Family Health ; Humans ; Models, Structural ; Spouses ; Surveys and Questionnaires