OBJECTIVE: To analyze the clinical characteristics of obese infertile women. MATERIAL AND METHOD: Height, weight, body mass index, menstrual pattern, glucose, insulin, glucose / insulin ratio, dehydroepiandrosterone sulfate (DHEA-S), testosterone, free testosterone and plasminogen activator inhibitor (PAI-1) of 15 obese infertile women were tested. RESULTS: Of 15 obese infertile women, the number of diabetes mellitus, hyperinsulinemia, and insulin resistance was 2 (13%), 2 (13%), 2 (13%), respectively. The incidence of increased DHEA-S, testosterone, and free testosterone was 7 (47%), 1 (7%), 6 (40%), respectively. Notably, all patients showed increased PAI-1. CONCLUSIONS: Obesity is associated with infertility as well as many kinds of health problems. Obesity is closely related to insulin resistance and it also causes hyperandrogenism. Increased PAI-1 is one of the important causes of thrombophilia. Consequently, in the workup of obese infertile patient, many aspects of health problems should be considered.
Body Weight ; Dehydroepiandrosterone Sulfate ; Diabetes Mellitus ; Female ; Glucose ; Humans ; Hyperandrogenism ; Hyperinsulinism ; Incidence ; Infertility ; Insulin ; Insulin Resistance ; Obesity ; Plasminogen Activator Inhibitor 1 ; Plasminogen Activators ; Testosterone ; Thrombophilia

No abstract available.
Thrombocythemia, Essential*

OBJECTIVE: To report the prevalence of lupus anticoagulants and anticardiolipin antibodies in patients with recurrent spontaneous abortion and infertility. MATERIAL AND METHOD: Lupus anticoagulants and anticardiolipin antibodies were analyzed by Diluted Russell's Viper Venom Test (DRVVT) and solid phase enzyme immunoassay, respectively. RESULTS: In 200 patients with infertility, there were 6 cases (3%) with positive lupus anticoagulants or anticardiolipin antibodies. Of these, 3 patients (1.5%) showed positive lupus anticoagulants and anticardiolipin antibodies, respectively. In 120 patients with recurrent spontaneous abortion, there were 13 cases (10.8%) of positive lupus anticoagulants or anticardiolipin antibodies. Of these, one patient (1%) showed lupus anticoagulants and 12 patients (10%) showed anticardiolipin antibodies. But in two groups, there was no cases with positive lupus anticoagulants and anticardiolipin antibodies. CONCLUSION: Lupus anticoagulants and anticardiolipin antibodies are definite cause of recurrent spontaneous abortion. There has been a speculation that they might be associated with infertility and repeated IVF failures. But it was found that the role of lupus anticoagulants and anticardiolipin antibodies in these cases are not clear.
Abortion, Spontaneous* ; Antibodies, Anticardiolipin* ; Anticoagulants* ; Female ; Humans ; Immunoenzyme Techniques ; Infertility* ; Pregnancy ; Prevalence ; Russell's Viper ; Venoms

Repeat cesarean section is one of the leading causes to make increasing a rate of cesarean section. Trial of labor TOL after cesarean section is attempt to reduce the rate of repeat cesarean section. Trial of labor has been well established as a safe alternative in carefully selected women with transverse scars in the lower uterine segment. This study was based on 104 cases of delivery with prior cesarean birth at the Chonbuk National University Hospital from January, 1991 to June, 1997. The results were as follows: 1) Among 1400 cases with previous cesarean delivery, trial of labor was done in 104 cases (7.4%). Among 104 cases, vaginal birth was successfully completed in 96 cases (92.3%). 2) Among 28 cases with PGE2, vaginal tablet, vaginal delivery was done in 23 cases (82.1%). 3) Among 22 cases with more than 4 of Bishop score, vaginal delivery was done in 21 cases (95.5%), and among 6 cases with less than 3 of Bishop score, vaginal delivery was done only 2 cases (33.3%). 4) There was no matemal death or uterine rupture in the cases of trial of labor, But in 2 cases, uterine dehiscence was observed in 4 cases and postpartal bleeding (more than 400ml) was developed. 5) In the cases of cesarean section, mean of hospital day was 7 days and medical fee was about 400,000 won. In the cases of vaginal birth after cesarean section, mean of hospital day was 2.6 days and medical fee was about 100,000 won. In condusion, vaginal birth after cesarean section is safe and effective alternative to elective repeat cesarean section and also the use of PGE, vaginal tablet is so effective to increase success rate of vaginal delivery. After all, positive these trials might decrease cesarean rate and increase maternal health and quality of medical care.
Cesarean Section ; Cesarean Section, Repeat ; Cicatrix ; Dinoprostone ; Fees, Medical ; Female ; Hemorrhage ; Humans ; Jeollabuk-do ; Maternal Health ; Parturition ; Pregnancy ; Prostaglandins E ; Trial of Labor ; Uterine Rupture ; Vaginal Birth after Cesarean* ; Vaginal Creams, Foams, and Jellies

Solid pseudopapillary tumor of the pancreas is a rare tumor that affects young females with low malignant potential and good prognosis with more than 90% survival at 5 years. Metastasis is very rare. We report the case of a 74-year-old female who had pancreatic solid-pseudopapillary tumor and synchronous hepatic metastasis.
Aged ; Female ; Humans ; Neoplasm Metastasis ; Pancreas ; Pancreatic Neoplasms ; Prognosis

Skin tags are very common skin tumors in middle age. In spite of their frequent occurrence, there was no reported cases of verruca vulgaris developing on the soft fibroma. We report a case of verruca vulgaris developing on the bag-like skin tag. We think that the incidence of HPV infection on the large skin tags may be higher than on normal skin due to their protrusion and repetitive irritation.
Fibroma ; Humans ; Incidence ; Middle Aged ; Skin* ; Warts*

BACKGROUND: Data on the frequency of Herpes Zoster are sparse, especially in inpatients OBJECTIVE: The purpose of this study was to elucidate the epidemilogy and the clinical characteristics of herpes zoster in inpatients. METHODS: During a 3-year-Period from Jan. 1991 to Dec. 1991, 157patients with herpes zoster were evaluated in regard to annual, monthly and seasonal incidence age incidenee and sex ratio. Patients with herpes zoster were further assessed concerning associratel conditions, dermatomic distributions and complications. RESULTS: 1. The annual rate ranged from 2.6% to 3.3% (mean 2.8%) and the ratio of male to female was 0.85: 1. 2. There were no marked manthly of spasonal differences in herpsoster, ranging from 4.5% to 10.8% and 21.7% to 31.2%, respectively. 3. Herpes Zoster was seen most frequently in the 50-59 year age group(27.4%) 4. The dermatomic involvernent of herpes zoster was most freqer t of thoracic dermatome(51.6%) and others were trigeminal(19.1%), cervical(13.4%), lumbar(6.4%), sacral(5.7%), facial(1.9%) and generalized(1.9%). 5. The frequency of associated conditions in herpes zoster was in d scending order, hypertension, tuberculosis, diabetes mellitus, malignancy, SLE, gastric ulcer, chronic renal failiure, rheumatoid arthritis, idiopathic pulmonary fibrosis. 6. The most common complication of herpes zoster was postheret c neuralgia and others were ophathalmologic complications, secondary bacterial infection, keloicl, formation, generalized varicelliform eruption, recurrent herpes zoster. CONCLUSION: Herpes Zoster is a major problem in the Department of Dermatology, especially in inpatients.
Arthritis, Rheumatoid ; Bacterial Infections ; Dermatology ; Diabetes Mellitus ; Female ; Herpes Zoster* ; Humans ; Hypertension ; Idiopathic Pulmonary Fibrosis ; Incidence ; Inpatients* ; Male ; Neuralgia ; Seasons ; Sex Ratio ; Stomach Ulcer ; Tuberculosis

BACKGROUND: Data on the frequency of Herpes Zoster are sparse, especially in inpatients OBJECTIVE: The purpose of this study was to elucidate the epidemilogy and the clinical characteristics of herpes zoster in inpatients. METHODS: During a 3-year-Period from Jan. 1991 to Dec. 1991, 157patients with herpes zoster were evaluated in regard to annual, monthly and seasonal incidence age incidenee and sex ratio. Patients with herpes zoster were further assessed concerning associratel conditions, dermatomic distributions and complications. RESULTS: 1. The annual rate ranged from 2.6% to 3.3% (mean 2.8%) and the ratio of male to female was 0.85: 1. 2. There were no marked manthly of spasonal differences in herpsoster, ranging from 4.5% to 10.8% and 21.7% to 31.2%, respectively. 3. Herpes Zoster was seen most frequently in the 50-59 year age group(27.4%) 4. The dermatomic involvernent of herpes zoster was most freqer t of thoracic dermatome(51.6%) and others were trigeminal(19.1%), cervical(13.4%), lumbar(6.4%), sacral(5.7%), facial(1.9%) and generalized(1.9%). 5. The frequency of associated conditions in herpes zoster was in d scending order, hypertension, tuberculosis, diabetes mellitus, malignancy, SLE, gastric ulcer, chronic renal failiure, rheumatoid arthritis, idiopathic pulmonary fibrosis. 6. The most common complication of herpes zoster was postheret c neuralgia and others were ophathalmologic complications, secondary bacterial infection, keloicl, formation, generalized varicelliform eruption, recurrent herpes zoster. CONCLUSION: Herpes Zoster is a major problem in the Department of Dermatology, especially in inpatients.
Arthritis, Rheumatoid ; Bacterial Infections ; Dermatology ; Diabetes Mellitus ; Female ; Herpes Zoster* ; Humans ; Hypertension ; Idiopathic Pulmonary Fibrosis ; Incidence ; Inpatients* ; Male ; Neuralgia ; Seasons ; Sex Ratio ; Stomach Ulcer ; Tuberculosis

Recent advances in bronchoscopy have led to changes in clinical diagnostics and therapeutics in pulmonary medicine. In diagnostic bronchoscopy, there have also been new developments in endobronchial ultrasound technology which may be incorporated into clinical practice in the near future. Functional bronchoscopy, which evaluates information such as airway pressure, airflow, or gas exchange, suggests promising clinical advances in the near future. In therapeutic bronchoscopy, bronchoscopic volume reduction is a novel approach for the treatment of severe emphysema. In this review, seven recently published articles representing current advances in bronchoscopy are summarized and discussed.
Bronchoscopy ; Emphysema ; Pulmonary Medicine ; Pulmonary Surgical Procedures

In order to investigate the risk factors of ischemic brain stroke (IBS) in diabetic patients, we analyzed 416 cases selected from 6239 diabetic patients admitted to Severance Hospital from Jan. 1983 to Dec 1987. Two hundred and eight cases had IBS. The other 208 cases without IBS were selected as a control group by a stratified random sampling method. The two groups were compared using various clinical characteristics of diabetes mellitus (DM) and known risk factors of IBS. In diabetics with IBS, the duration of DM was longer (9.2 +/- 7.1 years), hypertension was more frequently associated (68.2%) and the serum cholesterol level was higher (213.0 +/- 55.2 mg/dl) than in diabetics without IBS (7.6 +/- 7.1 years, 32.1% and 192.1 +/- 44.8 mg/dl, respectively). By means of Stepwise Logistic Regression Analysis (SLRA), it was found that the strong risk factors were hypertension and serum cholesterol level. The serum triglyceride level, type of DM and response to diabetes treatment were also thought to be risk factors of IBS by the retrial of SLRA of residuals after exclusion of hypertension and serum cholesterol level. IBS was not significantly related to the duration of DM, fasting blood glucose level, body weight, glycosylated hemoglobin value, and serum high-density lipoprotein-cholesterol level.
Adult ; Aged ; Aged, 80 and over ; Brain Ischemia/*etiology ; Cross-Sectional Studies ; Diabetes Mellitus/*complications ; Diabetic Angiopathies/*complications ; Female ; Human ; Korea ; Male ; Middle Age ; Retrospective Studies ; Risk Factors