1.Effect of tissue perfusion on temperature distribution in 915 MHz microwave hyperthermia.
Mi Kyung YANG ; Sung Hwan HA ; Chan Il PARK
Journal of the Korean Cancer Association 1993;25(5):736-743
No abstract available.
Fever*
;
Microwaves*
;
Perfusion*
2.Intra-abdominal Angiosarcomatosis Induced by Irradiation.
Hee Jin CHANG ; Youn Joo KIM ; Sung Eun YANG ; Sung Sook PAENG ; Jung Il SUH
Korean Journal of Pathology 1997;31(3):269-274
Therapeutic irradiation can induce angiosarcoma. Radiation-induced angiosarcoma constitutes 20% of all angiosarcomas. Although its common site of origin is the skin and subcutaneous tissue, it rarely arises in small or large bowels with a presentation as multifocal abdominal angiosarcomatosis. We report a case of intra-abdominal angiosarcomatosis involving the jejunum, ileum, transverse colon, mesentery and right ovary in a 63-year-old female. It developed 10 years after therapeutic irradiation for squamous cell carcinoma of uterine cervix. She developed panperitonitis due to intestinal perforation. She died from sepsis 3 days after segmental resection of the small bowel and right oophorectomy. We reviewed the previously reported cases and describe the clinicopathologic features of this tumor.
Carcinoma, Squamous Cell
;
Cervix Uteri
;
Colon, Transverse
;
Female
;
Hemangiosarcoma
;
Humans
;
Ileum
;
Intestinal Perforation
;
Jejunum
;
Mesentery
;
Middle Aged
;
Ovariectomy
;
Ovary
;
Sepsis
;
Skin
;
Subcutaneous Tissue
3.Immunohistochemical Study on Cytokeratin Expression in Epidermis of Human Fetus.
Sung Sik PARK ; Dong Ho YANG ; Kwang Il NAM ; Shin Kon KIM
Korean Journal of Physical Anthropology 1995;8(1):39-52
To identify the developmental characteristics of intermediate filaments, the expressions of various cytokeratines (CK), desmin and vimentin in fetal (14032 weeks of gestations) and adult epidermis were studied immunohistochemically. The primary antibodies used were CK7, 8, 10, 14, 18, AE8, 5D3, and MNFl16 for cytokeratins, D33 for desmin, and V9 for vimentin. At 14 weeks of gestation, the epidermis consisted of basal cells and periderm. The periderm exhibited positive staining for CK8 and AE8, and weak staining for MNF116 and D33. The basal cells showed positive staining for MNF116 and D33. The epidermis did not reacted for CK7, 10, 14, 18, 5D3, and V9 at this period. At 16-20 weeks of gestation, the epidermis was composed of basal, intermediate, and periderm layers. The periderm was positive for CK8, 18, AE8, MNF116, and D33. The intermediate cells were positive for CK10 and the basal cells CK14, MNF116, and D33. Few cells were stained positively with V9 among the basal cells. At 24-32 weeks of gestation, the epidermis exhibited no longer positive reactions for CK8, 18, AE8 and D33. The intermediate cells were positive for CK10. Immunoreactivity for MNF116 was noted in intermediate layer just above the basal layer. CKl4, MNFl16, D33, and often V9 were expressed in basal cells. The expressions of CK7 and 5D3 were not observed at any period of gestation. In adult epidermis, basal cells exhibited positive staining for CKl4, MNFl16, and D33. The intermediate cells were strongly positive for CK10, and weakly positive for CK7, 8, and MNFl16. The cells positive for V9 were often present among the basal cells. These results indicate that CK8 and 18 may serve as useful markers for periderm, CK10 for intermediate cells, CKl4 for basal cell, and suggest that the vimentin immunoreactive cells in basal cell layer are Langerhans cells.
Adult
;
Antibodies
;
Desmin
;
Epidermis*
;
Fetus*
;
Humans*
;
Immunohistochemistry
;
Intermediate Filaments
;
Keratins*
;
Langerhans Cells
;
Pregnancy
;
Vimentin
4.Clinical Evaluation of Traumatic Cataract with Corneal Laceration.
Journal of the Korean Ophthalmological Society 2000;41(5):1170-1176
The cataract extraction in traumatic cataract with corneal laceration is likely to be different from the ordinary cataract extraction in several points. We tried to know the problems of the operation, the visual outcomes and the postoperative complications in these eyes. In 25 traumatic cataract with corneal laceration, we performed cataract extraction and corneal suture at the same time in 11 eyes and at different time in 14 eyes. The intraoperative problems were difficult anterior capsulotomy, corneal opacity, difficult lens delivery etc.The major postoperative complications were anterior chamber inflammation, corneal edema, posterior capsular opacity and exudative pupillary membrane. In 23 eyes[92%], the visual acuity was increased more than 2 lines. Cataract extraction in traumatic cataract with corneal laceration was very effective surgery, and cataract extraction after primary corneal suture has done had good results in severe corneal laceration with suspicious posterior capsular rupture and non-fitted preoperative preparation.
Anterior Chamber
;
Cataract Extraction
;
Cataract*
;
Corneal Edema
;
Corneal Opacity
;
Inflammation
;
Lacerations*
;
Membranes
;
Postoperative Complications
;
Rupture
;
Sutures
;
Visual Acuity
5.Clinical Significance of Axillary Lymph Nodes a Observed in Mediolateral Oblique View of IVlammography.
Ik YANG ; Yul LEE ; Soo Young CHUNG ; Bo Whan CHOI ; Young Mook KIRN ; Il Sung LEE
Journal of the Korean Radiological Society 1995;32(1):181-184
PURPOSE: To evaluate the radiologic characteristics of axillary lymph nodes which are found on mediolateral oblique(MLO) view of mammography and to assess their clinical significance. MATERIALS AND METHODS: We retrospectively evaluated 119 cases axillary lymph nodes on MLO view of 410 cases of mammography in 205 patients regarding the size, bilaterality, number, grade of density, presence of central lucency, calcification of lymph nodes and presence of associated parenchymal pathologic lesions in breast. RESULTS: Axillary lymph nodes on MLO view were demonstrated in 119 (29%) among 410 cases. Axillary lymph nodes(112 cases) in cases without breast parenchymal lesions or with benign breast lesions showed; unilaterality in 68 cases(61%), smaller than 1.5cm in 100 cases(89%), lower density than breast parenchyma in 99 cases(88%), presence of central lucency in 99 cases(88%) and calcification in 3 cases(2.7%). Axillary lymph nodes(7 cases)in cases with breast cancer showed small size of less than 1.5cm in 4 cases(57%), absence of central lucency in 7 cases(100%) and iso-to higher density than breast parenchyma in 7 c&ses(100%). CONCLUSION: Axillary lymph nodes noted on MLO view of mammography, more than 1.5cm in diameter, absence of central lucency and iso to higher density than breast parenchyma could be suggested as clinically significant.
Breast
;
Breast Neoplasms
;
Humans
;
Lymph Nodes*
;
Mammography
;
Retrospective Studies
6.Clinical Significance of Axillary Lymph Nodes a Observed in Mediolateral Oblique View of IVlammography.
Ik YANG ; Yul LEE ; Soo Young CHUNG ; Bo Whan CHOI ; Young Mook KIRN ; Il Sung LEE
Journal of the Korean Radiological Society 1995;32(1):181-184
PURPOSE: To evaluate the radiologic characteristics of axillary lymph nodes which are found on mediolateral oblique(MLO) view of mammography and to assess their clinical significance. MATERIALS AND METHODS: We retrospectively evaluated 119 cases axillary lymph nodes on MLO view of 410 cases of mammography in 205 patients regarding the size, bilaterality, number, grade of density, presence of central lucency, calcification of lymph nodes and presence of associated parenchymal pathologic lesions in breast. RESULTS: Axillary lymph nodes on MLO view were demonstrated in 119 (29%) among 410 cases. Axillary lymph nodes(112 cases) in cases without breast parenchymal lesions or with benign breast lesions showed; unilaterality in 68 cases(61%), smaller than 1.5cm in 100 cases(89%), lower density than breast parenchyma in 99 cases(88%), presence of central lucency in 99 cases(88%) and calcification in 3 cases(2.7%). Axillary lymph nodes(7 cases)in cases with breast cancer showed small size of less than 1.5cm in 4 cases(57%), absence of central lucency in 7 cases(100%) and iso-to higher density than breast parenchyma in 7 c&ses(100%). CONCLUSION: Axillary lymph nodes noted on MLO view of mammography, more than 1.5cm in diameter, absence of central lucency and iso to higher density than breast parenchyma could be suggested as clinically significant.
Breast
;
Breast Neoplasms
;
Humans
;
Lymph Nodes*
;
Mammography
;
Retrospective Studies
7.Effects of taurine on generalized seizure activity in the rat thalamocortical slice.
Sung Gu YANG ; Il Keun LEE ; Chang Joong LEE
Journal of the Korean Neurological Association 1997;15(6):1236-1246
Rat thalamocortical slices maintain synoptic connections between thalamus and cortex. When perfused with low Mg++-ACSF, thalamocortical slices exhibited two main types of spontaneous bursting activity. One is monotonic burst of 3-15 Hz and another is multiphasic bursts which have a tonic burst firing period and a late phase of clonic burst firing. These bursts are similar in frequency and during to EEG recordings from human generalized seizures. Exploiting the advantages of in vitro preparations, the electrophysiological action of taurine were studied. Exogeneous application of taurine profoundly decreased spontaneous bursting activities, which it caused only slight reduction of electrically evoked response in cortical layer. Taurine-induced current was blocked by 40 uM bicuculline, GABA receptor antagonist, in acutely isolated coritcal neurons. These results suggest that endogeneous taurine may regulate the hyperexcitablility through GABAa receptor.
Animals
;
Bicuculline
;
Electroencephalography
;
Fires
;
Humans
;
Neurons
;
Rats*
;
Receptors, GABA
;
Seizures*
;
Taurine*
;
Thalamus
8.Effects of taurine on generalized seizure activity in the rat thalamocortical slice.
Sung Gu YANG ; Il Keun LEE ; Chang Joong LEE
Journal of the Korean Neurological Association 1997;15(6):1236-1246
Rat thalamocortical slices maintain synoptic connections between thalamus and cortex. When perfused with low Mg++-ACSF, thalamocortical slices exhibited two main types of spontaneous bursting activity. One is monotonic burst of 3-15 Hz and another is multiphasic bursts which have a tonic burst firing period and a late phase of clonic burst firing. These bursts are similar in frequency and during to EEG recordings from human generalized seizures. Exploiting the advantages of in vitro preparations, the electrophysiological action of taurine were studied. Exogeneous application of taurine profoundly decreased spontaneous bursting activities, which it caused only slight reduction of electrically evoked response in cortical layer. Taurine-induced current was blocked by 40 uM bicuculline, GABA receptor antagonist, in acutely isolated coritcal neurons. These results suggest that endogeneous taurine may regulate the hyperexcitablility through GABAa receptor.
Animals
;
Bicuculline
;
Electroencephalography
;
Fires
;
Humans
;
Neurons
;
Rats*
;
Receptors, GABA
;
Seizures*
;
Taurine*
;
Thalamus
9.A Clinical Observation on Disease of Pediatric Urology.
Korean Journal of Urology 1981;22(1):35-39
A clinical observation was made on the patients who had been admitted to the Department of Urology, Chosun University Hospital during the period from January, 1972 to December, 1979. The results were as follows 1. Pediatric patients were 78 of 867 total urologic patients giving the rate of 9.0%. The ratio of male to female pediatric in-patients was 7.7:1. 2. School children (6 to 12 years of age) were most frequently seen(39.7%). 3. The most common disease was genitourinary anomaly a ratio of 32.1%. The other diseases were hydrocele in 16.7%, stone in 9%, tumor and non specific infection in 6.4%. 4. The most frequently involved organ was testis in 25 cases (32.1%). The others were urethral disease in 24 cases (30.8%), renal disease in 13 cases (16.7%), vesical disease in 4 cases (5.1%), ureteral disease in 3 cases (3.8%) and penile disease in 2 cases (2.6%). 5. Of 78 patients, 68 operations were performed in 59 patients. The most common operation was hydrocelectomy in 13 cases. The other operations were orchiopexy in 11 cases, urethroplasty in 10 cases, correction of chordee in cases, lithotomy in 7 cases and circumcision in 2 cases. 6. The most common duration of hospitalization was from 1 to 2 weeks.(52.6%).
Child
;
Circumcision, Male
;
Female
;
Hospitalization
;
Humans
;
Male
;
Orchiopexy
;
Penile Diseases
;
Testis
;
Ureteral Diseases
;
Urethral Diseases
;
Urology*
10.A Clinical Observation on Disease of Pediatric Urology.
Korean Journal of Urology 1981;22(1):35-39
A clinical observation was made on the patients who had been admitted to the Department of Urology, Chosun University Hospital during the period from January, 1972 to December, 1979. The results were as follows 1. Pediatric patients were 78 of 867 total urologic patients giving the rate of 9.0%. The ratio of male to female pediatric in-patients was 7.7:1. 2. School children (6 to 12 years of age) were most frequently seen(39.7%). 3. The most common disease was genitourinary anomaly a ratio of 32.1%. The other diseases were hydrocele in 16.7%, stone in 9%, tumor and non specific infection in 6.4%. 4. The most frequently involved organ was testis in 25 cases (32.1%). The others were urethral disease in 24 cases (30.8%), renal disease in 13 cases (16.7%), vesical disease in 4 cases (5.1%), ureteral disease in 3 cases (3.8%) and penile disease in 2 cases (2.6%). 5. Of 78 patients, 68 operations were performed in 59 patients. The most common operation was hydrocelectomy in 13 cases. The other operations were orchiopexy in 11 cases, urethroplasty in 10 cases, correction of chordee in cases, lithotomy in 7 cases and circumcision in 2 cases. 6. The most common duration of hospitalization was from 1 to 2 weeks.(52.6%).
Child
;
Circumcision, Male
;
Female
;
Hospitalization
;
Humans
;
Male
;
Orchiopexy
;
Penile Diseases
;
Testis
;
Ureteral Diseases
;
Urethral Diseases
;
Urology*