No abstract available.
Aortic Aneurysm*

Carcinoembryonic antigen(CEA) was measured in the serum and urine of 46 patients with bladder cancer and 15 patients with non-cancer disease as control group at the Paik Hospital. Pusan during the period from January, 1986 to June, 1988. The following results were obtained. 1. The upper limits of normal serum and urinary CEA levels in non tumor control group were 3.7 ng/ml and 2.3 ng/ml. Mean and positive rate of serum and urinary CEA levels in bladder cancer group were 4.40 ng/ml(37.0%) and 21.52ng/ml(65.2%). 2. Mean urinary CEA level was correlated significantly with the stage, grade and size of bladder cancer but no significance was seen in serum CEA. In the advanced cases(Stage C, D), serum CEA levels were elevated. 3. The diagnostic rate was not elevated in spite of urinary CEA determination combined with urinary cytology. After transurethral resection of cancer mass and radiation therapy, urinary CEA level decreased. As a result, serum and urinary CEA determinations in bladder cancer have no diagnostic value, but it will be useful in the study of the extent of cancer, effect of therapy, recurrence and prognosis.
Busan ; Carcinoembryonic Antigen ; Humans ; Prognosis ; Recurrence ; Urinary Bladder Neoplasms* ; Urinary Bladder*

The study consisted of all patients over 35yerars old undergoing surgical repair of atrial septal defect for the period from June 1985, to August 1992. The following results were observed. 1. ASD was closed with patch in 11 (73%) patients. 2. The relationship of pulmonary artery systolic pressure to Qp/Qs ratio was not significant. 3. Before operation 6 patients were in NYHA functional class II. 8 were in class III, After operation 8 patients were in class I, 6 were in class II. 4. Atrial fibrillation has persisted in 3 patients and returned regular rhythm in 1 patient after surgery. 5. There was no operative mortality and we had good surgical results regardless of patient's age.
Adult* ; Atrial Fibrillation ; Blood Pressure ; Heart Septal Defects, Atrial* ; Humans ; Mortality ; Pulmonary Artery

No abstract available.
Extracorporeal Circulation* ; Plasma*

No abstract available.
Lung*

No abstract available.
Aortic Coarctation* ; Child, Preschool* ; Humans

PURPOSE: To evaluate the usefulness of Gd-DTPA enhanced MR imaging in determining the metastatic lymph nodes in uterine cervical carcinoma. MATERIALS AND METHODS: Sixty nine patients with histologically proven cervical carcinoma underwent Gd-DTPA enhanced MR imaging. One hundred and thirty-eight pelvic regions(69 right,69 left) in 69 patients were analyzed for lymph node metastases. Pelvic lymph nodes were considered to be abnormal if they were greater than lcm in diameter and were enhanced on postcontrast T1 weighted images. RESULTS: Metastatic lymph nodes were found in 22 pelvic regions by surgicopathologic examinations. On MR imaging there were 14 true positives, 106 true negatives, 10 false positives and 8 false negatives. Gd-DTPA enhanced MR image had an accuracy of 86.9%, a sensitivity of 58.3%, a specificity of 91.4%, a positive predictive value of 58.3% and negative predictive value of 92.9% in evaluation of pelvic lymph node metastases. CONCLUSION: MR imaging with contrast enhancement may be useful in the evaluation of pelvic lymph node metastases in patients with uterine cervical carcinoma.
Gadolinium DTPA ; Humans ; Lymph Nodes* ; Magnetic Resonance Imaging* ; Neoplasm Metastasis ; Pelvis ; Sensitivity and Specificity

PURPOSE: To evaluate CT features of metastatic ureteral tumors. MATERIALS AND METHODS: CT findings in 16 patients with ureteral metastases were evaluated retrospectively ;there were eight cases of bilateral ureteral involvement. Primary tumors metastatic to the ureter were advanced gastric cancer (n=13), breast cancer (n=l), colon cancer (n=l), or adenocarcinoma of unknown primary (n=l). We analysed CT findings with regard to the site of ureteral obstruction, configuration of obstructed sites of ureter, presence or absence of periureteral soft tissue density, and status in other organs. RESULTS: Among 24 ureters involved, ureteral wail thickening was noted in 15, periureteral soft tissue density in 13. Small nodular enhancing lesions less than lcm, within the retroperitoneal space around the involved ureters were noted in seven patients, and four of them were multiple lesions. CONCLUSION: Among various primary tumors, gastric cancer was the most common cause of ureteral metastasis. The common CT findings of ureteral metastases were thickening of ureteral wall, periureteral soft tissue density, and small periureteral enhancing nodular lesions. The constellation of these CT findings may be helpful in making the diagnosis of ureteral metastases.
Adenocarcinoma ; Breast Neoplasms ; Colonic Neoplasms ; Diagnosis ; Humans ; Neoplasm Metastasis* ; Retroperitoneal Space ; Retrospective Studies ; Stomach Neoplasms ; Ureter* ; Ureteral Obstruction

An experimental study in vitro using piezoelectric extracorporeal shock wave lithotriptor(EDAP LT-01) and urinary stones removed from the patients by surgical method has been performed. The purposes were 1) to correlate the stone components and sizes with the storage of complete fragmentation, 2) to examine the screening effect and 3) to observe the stone fracture mechanism in urinary stones. The following results were obtained. 1. Tribasic calcium phosphate stone, magnesium ammonium phosphate stone and uric acid stone fractured more easily than calcium oxalate stone. In the case of small stones(diameter 0.5 cm), all stones fractured at relatively low storage. Large stones (diameter 1.5 cm) fractured at high storage with wide variations according to components. 2. Magnesium ammonium phosphate stones tested to observe for screening effect showed that a high storage was needed for complete fragmentation(about 2 times) when the stone debris was not removed. 3. Urinary stones fractured first on the front surface. When the stones showed lamellae, which were separated first by shock wave, thereafter each lamella was broken.
Ammonium Compounds ; Calcium ; Calcium Oxalate ; Humans ; Magnesium ; Mass Screening ; Shock* ; Uric Acid ; Urinary Calculi

BACKGROUND: Cardiopulmonary bypass during open heart surgery causes systemic inflammatory respose. IL-10 is an anti-inflammatory cytokine that inhibits inflammatory process and protects organ function by down regulation of pro-inflammatory cytokine release and maintenance of blood level balance with pro-inflammatory cytokines. MATERIAL ateial and Method: Plasma IL-10 levels were measured and analyzed in 22 patients who underwent open heart surgery (11 cases of coronary artery bypass graft, 11 cases of valve replacement) under cardiopulmonary bypass since 1988 January to July at Department of Thoracic and Czardiovascular surgery, Yeungnam University Hospital. 1g of methylprednisolone was administrated to thirteen patients randomly. Blood samp.es were taken and collected at the time of induction of anesthesia, 10 min before cardiopulmonary bypass, 10 min after starting of CPB, 10 min aftr aortic cross clamping, 10 min after ACC release, and 10 min, 2 hours, and 5 hours after CPB respectively. The plasma levels of IL-10 were determined by enzyme-linked immunosorbent assays (ELISA). Wilcoxon-Raule Sum test was used for statistical analysis. In all 22 patients, cardiopulmonary bypass time was used for statistical analysis. In all 22 patients, cardiopulmonary bypass time was 171+/-41.4 min and aortic cross clamp time was 118+/-36.5 min. Peak IL-10 level was achieved at 10 min after ACC (361.0+/-52.81pg/ml) and was decreased sharply at 2 hours after CPB. Peak IL-10 level was correlated positively with aortic cross clamp time (p=0.011); however, it did not correlated with bypass time (p=0.181). In valve replacement group, mean IL-10 level at peak point was 567.89+/-107.69 pg/ml and was significantly higher than that of coronary artery bypass group (205.67+/-192.70 pg/ml) (p<0.001). ACC time in valve replacement group was significantly longer than that of coronary artery bypass group (p<0.01), however, bypass time was not (p=0.212). Thirteen patients with steroid pretreatment before starting of CPB showed relatively higher plasma IL-10 level than in control group, however, no statistical significance was noted (p=0.19). CONCLUSION: plasma level of IL-10 was increased in association with cardiopulmonary bypass and revealed peak at 10 min after ACC release. IL-10 level was correlated positively with ACC time. Therefore, systemic inflammatory respeonse in association with cardiopulmonary bypass could be decreased by reducing ACC time during cardiac surgery.
Anesthesia ; Cardiopulmonary Bypass* ; Constriction ; Coronary Artery Bypass ; Cytokines ; Down-Regulation ; Enzyme-Linked Immunosorbent Assay ; Humans ; Interleukin-10* ; Methylprednisolone ; Plasma ; Thoracic Surgery ; Transplants