1.Information processing and its neuroanatomy in schizophrenia.
Journal of Korean Neuropsychiatric Association 1991;30(4):629-651
No abstract available.
Automatic Data Processing*
;
Neuroanatomy*
;
Schizophrenia*
2.The Neuroanatomy and Psychophysiology of Attention.
Sleep Medicine and Psychophysiology 1998;5(2):119-133
Attentional processes facilitate cognitive and behavioral performance in several ways. Attention serves to reduce the amount of information to receive. Attention enables humans to direct themselves to appropriate aspects of external environmental events and internal operations. Attention facilitates the selection of salient information and the allocation of cognitive processing appropriate to that information. Attention is not a unitary process that can be localized to a single neuroanatomical region. Before the cortical registration of sensory information, activation of important subcortical structures occurs, which is called as an orienting response. Once sensory information reaches the sensory cortex, a large number of perceptual processes occur, which provide various levels of perceptual resolution of the critical(heteromodal) systems inferior parietal and temporal lobes. At this stage, the processing characteristics can be modified, and the biases of the system have a direct impact on attentional selection. Information flow has been traced through sensory analysis to a processing stage that enables the new. Information to be focused and modified in relation to preexisting biases. The limbic and paralimbic system play significant roles on modulating attentional response. It is labeled with affective salience and is integrated according to ongoing pressures from the motivational drive system of the hypothalamus. The salience of information greatly influences the allocation of attention. The frontal lobe operate resporse selection system with a reciprocal interaction with both the attention system of the parietal lobe and the limbic system. In this attentional process, the search with the spatial field is organized and a sequence of attentional responses is generated. Affective, motivational and appectitive impulses from limbic system and hypothalamus trigger response intention, preparation, planning, initiation and control of frontal lobe on this process. The reticular system, which produces ascending activation, catalyzes the overall system and increases attentional capacity. Also additional energetic pressures are created by the hypothalamus. As psychophysiological measurement, skin conductance, pupil diameter, muscle tension, heart rate, alpha wave of EEG can be used. Event related potentials also provide physiological evidence of attention during information process. N1 component appears to be an electrophysiological index of selective attention. P3 response is developed during the attention related to stimulus discrimination, evaluation and response.
Automatic Data Processing
;
Bias (Epidemiology)
;
Discrimination (Psychology)
;
Electroencephalography
;
Evoked Potentials
;
Frontal Lobe
;
Heart Rate
;
Humans
;
Hypothalamus
;
Intention
;
Limbic System
;
Muscle Tonus
;
Neuroanatomy*
;
Parietal Lobe
;
Psychophysiology*
;
Pupil
;
Rabeprazole
;
Skin
;
Temporal Lobe
3.The celluar composition including lymphocyte subsets in colostrum and mature milk from mothers of preterm and full term infancy.
Young Hoon KIM ; Joon Sung LEE ; Sung Hoon CHO
Pediatric Allergy and Respiratory Disease 1993;3(2):20-31
No abstract available.
Colostrum*
;
Humans
;
Lymphocyte Subsets*
;
Lymphocytes*
;
Milk*
;
Mothers*
4.A clinical and histopathologic study of benign odontogenic tumors.
Sung Hoon CHUNG ; Eui Wung LEE
Journal of the Korean Association of Oral and Maxillofacial Surgeons 1991;17(2):83-96
No abstract available.
Odontogenic Tumors*
6.The relationship between simple attention and clinical symptoms in schizophrenia.
Journal of Korean Neuropsychiatric Association 1992;31(2):252-257
No abstract available.
Schizophrenia*
7.Immunologic Changes in Bronchial Asthma on Immunotherapy.
Joon Sung LEE ; Kyung Tai WHANG ; Sung Hoon CHO
Journal of the Korean Pediatric Society 1990;33(9):1255-1261
No abstract available.
Asthma*
;
Immunotherapy*
8.The effect of respiratory syncytial virus infection on neutrophil adherence to airway epithelial cells.
Hyun Hee KIM ; Joon Sung LEE ; Sung Hoon CHO
Journal of Asthma, Allergy and Clinical Immunology 1999;19(1):50-61
BACKGROUND: Respiratory syncytial virus (RSV) is the most common cause of lower respiratory infection in infants and young children, but the pathogenesis of RSV-induced inflammation is not well defined. MATERIAL AND METHOD: In order to examine the potential interactions between virus-infected airway epithelial cells and neutrophils, we studied the ability of neutrophils to adhere to yirus-infected airway epithelial cell monolayers by myeloperoxidase assay. Also we measured the ability of airway epithelial cells to secrete interleukin-8(IL-8) and inter-cellular adhesion molecule-1(ICAM-1) in virus-infected airway epithelial cell cultures by enzyme-linked immunosorbent assay(ELISA). The degree of IL-8 and ICAM-1 gene expression in the RSV-infected BEAS-2B cell cultures were analyzed by reverse transcription-polymerase chain reaction(RT-PCR). RESULTS: The RSV-infected BEAS-2B cell resulted in significantly enhanced level of neutrophil adherence compared to the uninfected control(p (0.001). IL-8 and ICAM-1 production significantly increased by RSV infection(p<0.05). There was a significant positive correlation between neutrophil adherence and IL-8 level(r=0.73, p=0.002), and ICAM-1 level (r=0.843, p=0.001) in RSV-infected cells. The degree of both IL-8 and ICAM-1 mRNA expression increased in the RSV-infected cells compared with the uninfected ones. CONCLUSION: These results suggest that RSV infection significantly enhances the production of IL-8 and ICAM-1 in airway epithelial cells which then results in increased neutrophil adherence.
Cell Culture Techniques
;
Child
;
Epithelial Cells*
;
Gene Expression
;
Humans
;
Infant
;
Inflammation
;
Intercellular Adhesion Molecule-1
;
Interleukin-8
;
Neutrophils*
;
Peroxidase
;
Respiratory Syncytial Viruses*
;
RNA, Messenger
9.T lymphocyte responses to house dust mite in asthmatic children.
Joon Sung LEE ; Hyung Kook KIM ; Sung Hoon CHO
Pediatric Allergy and Respiratory Disease 1993;3(1):59-67
No abstract available.
Child*
;
Dust*
;
Humans
;
Lymphocytes*
;
Pyroglyphidae*
10.Clinical Analysis of Congenital Malformations in the Newborn Infant.
In Kyung SUNG ; Byung Churl LEE ; Sung Hoon CHO
Journal of the Korean Pediatric Society 1988;31(1):72-77
No abstract available.
Humans
;
Infant, Newborn*