Search Results

This report offers descriptive data about the drugs utilized in outpatient department (OPD) of Yeungnam University Hospital (YUH) in the period of March to August in 1985. The data in this report were produced by the computerized totalization of the number of mentions of individual drugs included in the prescriptions. The 100 drug entries that were most frequently recorded are listed in rank order. The listing is arbiturarily restricted to the drugs that were prescribed as single preparations, the drugs of basis of compound preparations and the drugs of adjuvant or corrective of compound preparations that have significant therapeutic effects either by generic names. And in addition, the listing also involves the compound preparations used in relatively large frequency, and the individual components of which have the unique pharmacological actions each other by proprietary names. And all routes of administrations were allowed. The 10 drugs most frequently named are diazepam, aluminum compounds, acetaminophen, isoniazid, metoclopramide, polaramine®, carboxymethylcystein, ephedrine, codeine and caroverine in order. The 521, 855 drug mentions listed as above are described by the chief therapeutic usage that each is intended to apply generally. The drugs which account the largest proportion of total mentions were those acting on the central nervous system (20.57%), including tranquillizers and sedative hypnotics (11.71%), analgesic antipyretics (5.55%), antidepressants (2.15%) etc. Gastrointestinal drugs and smooth muscle preparations (18.64%) included antacids and antiulcer drugs (9.24%), antiemetics (3.57%), spasmolytics (3.14%) and others. Respiratory drugs (16.11%) included expectorants and cough preparations (10.99%) and bronchodilators (5.12%). Chemotherapeutic agents (15.12%) included the antiTbc drugs (7.09%) most frequently, and the penicillins (3.33%) accounted the largest proportion among the antibiotics. Cardiovascular drugs (5.64%) included cardiac drugs and coronary vasodilator (4.12%) and antihypertensives and vasodilators (1.06%). And antiinflammatory drugs (4.33%), vitamins of single preparations (3.76%), hormones and their antagonists (3.29%), common cold preparations (3.12%), diuretics (2.81%), drugs supporting liver function (2.02%), drugs affecting autonomic nervous system (1.89%) including antiglaucomas, atropine and cerebral vasodilators, antihistamine drug (1.02%) and disinfectants (0.74%) were following in order. The data in the report were compared to those reported by H. Koch, et al. in United States (US), 1981 as “Drugs Most Frequently Used in Office Practice : National Ambulatory Medical Case Survey, 1981.” Cardiovascular drugs prescribed in YUH were much less in proportion than in US (10.56%), but gastrointestinal drugs accounted the larger proportion than in US (3.72%). Expectorants and preparations in YUH also accounted the larger proportion than in US (2.74%). In conclusion, in the period of March to August, 1985, OPD of YUH prescribed the CNS drugs including diazepam most frequently, and gastrointestinal, respiratory and chemotherapeutic drugs in next orders. It is supposed that the eating habits of Koreans and a unique atmospheric condition in Taegu as a basin were some important factors that affected the proportions of drugs acting on gastrointestinal and respiratory tracts.
Acetaminophen ; Aluminum Compounds ; Antacids ; Anti-Bacterial Agents ; Antidepressive Agents ; Antiemetics ; Antihypertensive Agents ; Antipyretics ; Atropine ; Autonomic Nervous System ; Bronchodilator Agents ; Cardiovascular Agents ; Central Nervous System ; Codeine ; Common Cold ; Cough ; Daegu ; Diazepam ; Disinfectants ; Diuretics ; Eating ; Ephedrine ; Expectorants ; Gastrointestinal Agents ; Humans ; Hypnotics and Sedatives ; Isoniazid ; Liver ; Metoclopramide ; Muscle, Smooth ; Outpatients ; Parasympatholytics ; Penicillins ; Prescriptions ; Respiratory System ; Therapeutic Uses ; United States ; Vasodilator Agents ; Vitamins

Following chemotherapy and radiation treatment for infiltrating ductal carcinoma of the left breast, a 50-year-old woman presented with a child's palm sized, crusted patch and surrounding peanut sized granulated nodules on the lesion, which was diagnosed as primary cutaneous aspergillosis caused by Aspergillus fumigatus. No evidence of involvement of other organs or of systemic dissemination by Aspergillus femigatus was found. Also the patient exhibited no other apparent systemic immunologic defects. Extensive excision were performed and the patient received treatment with amphoteriein B. No evidence of recurrent fungal infection was noted during 6 months of follow-up.
Aspergillosis* ; Aspergillus ; Aspergillus fumigatus ; Breast Neoplasms* ; Breast* ; Carcinoma, Ductal ; Drug Therapy ; Female ; Follow-Up Studies ; Humans ; Middle Aged