No abstract available.
Aspirin* ; Mucocutaneous Lymph Node Syndrome*

PURPOSE: Although magnetic attachment is used frequently for overdenture, it is reported that attractive force can be decreased by abrasion and corrosion. The purpose of this study was to establish the clinical basis about considerations and long term prognosis of overdenture using magnetic attachments by investigating the change in attractive force of magnetic attachment applied to the patients. MATERIALS AND METHODS: Among the patients treated with overdenture using magnetic attachments in Dankook University Dental Hospital, attractive force records of 61 magnetic attachments of 20 subjects who re-visited from July 2013 to June 2014 were analyzed. Dental magnet tester (Aichi Micro Intelligent Co., Aichi, Japan) was used for measurement. The magnetic attachments used in this study were Magfit IP-B Flat, Magfit DX400, Magfit DX600 and Magfit DX800 (Aichi Steel Co., Aichi, Japan) filled with Neodymium (NdFeB), a rare-earth magnet. RESULTS: Reduction ratio of attractive force had no significant correlation with conditional variables to which attachments were applied, and was higher when the maintenance period was longer (P<.05, r=.361). Reduction ratio of attractive force was significantly higher in the subject group in which attachments were used over 9 years than within 9 years (P<.05). Furthermore, 16.39% of total magnetic attachments showed detachment of keeper or assembly. CONCLUSION: Attractive force of magnetic attachment is maintained regardless of conditional variables and reduction ratio increased as the maintenance period became longer. Further study on adhesive material, attachment method and design improvement to prevent detachment of magnetic attachment is needed.
Adhesives ; Corrosion ; Denture, Overlay* ; Effect Modifier, Epidemiologic ; Humans ; Neodymium ; Prognosis ; Steel

The precise role of radiotherapy for low grade gliomas including the optimal radiation dose and timing of treatment remains unclear. The information given by a retrosepctive analysis may be useful in the design of prospective randomized studies looking at radiation dose and time of surgical and radiotherapeutic treatment. The records of 56 patients (M:F=29:27) with histologically verified cerebral low grade gliomas(47 cases of grade 1 or 2 astrocytomas and 9 oligodendrogliomas) diagnosed between 1979 and 1989 were retrospectively reviewed. The extent of surgical tumor removal was gross total or radical subtotal in 38 patients(68%) and partial or biopsy only in the remaining 18 patients(32%). Postooperative radiation therapy was given to 36 patients(64%) of the total 56 patients with minimum dose of 5000 cGy (range=1250 to 7220 cGy). The 5-and 10-year survival rates for the total 56 patients were 44% and 32% respectively with a median survival of 4.1 years. According to the histologic grade the 5- and 10-year survivals were 52% and 35% for the 24 patients respectively with grade I astrocytomas compared to 20% and 10% for the 23 patients with grade II astrocytomas. Survival of oligodendroglioma patients was greater than those with astrocytoma (65% vs 36% at 5 years), and the difference was also remarkable in the long term period of follow up (54% vs 23% at 10 years). Those who received high-dose radiation therapy (> or =5400 cGy) had significant better survival than those who received low-dose radiation(< 5400 cGy) or surgery alone (p<0.05). The 5-and 10-year survival rates were, respectively 59% and 46% for the 23 patients receiving high-dose radiation, 36% and 24% for the 13 patients receiving low-dose radiation, and 35% and 26% for the 20 patients with surgery alone. Survival rates by the extent of surgical resection were similar at 5 years (46% vs 41%), but long term survival was quite different (p<0.01) between total/subtotal resection and partial esection/biopsy (41% and 12%, resepctively). Previously published studies have identified important prognostic factors in these tumor : age, extent of surgery, grade, performance status, and duration of symptoms. But in our cases statistical analysis revealed that grade I histology (p<0.025) and young age (p<0.001) were the most significant good prognostic variables.
Astrocytoma ; Biopsy ; Brain Neoplasms ; Follow-Up Studies ; Glioma ; Humans ; Oligodendroglioma ; Radiotherapy* ; Retrospective Studies ; Survival Rate

Electrical stimulation has been used for evaluating central motor system and deep portion of peripheral nerve, but it was painful. And then magnetic stimulation was introduced recently and used widely because it was painless and easily repeated, compared to electrical stimulation. This study was undertaken in order to obtain normal valued of motor evoked potentials by transcranial magnetic stimulation. Ninety-two volunteers, free of neurological disease, were tested with Medelec Magstim model 200 and Medelec MIstral. There were 55 male and 37 female, ranging in height from 130 to 180 centimeter, with a mean height of 165.9 centimeter, in age from 13 to 70 years, with a mean age of 34 years. Transcranial magnetic stimulation cause contralateral hand and foot muscle responses, and the resultant motor evoked potentials can be recorded. Stimulating sites were near vertex in head, Erb's point in cervical region and L45 interspace in lumbar region. Recording sites wre abductor pollicis brevis(APB) in hand and abductor hallucis(AH) in foot. Our results were as follow ; 1) Latency between head and contralateral APB was 20.9+/-1.5ms, latency between cervical region and ipsilateral APB was 11.7+/-1.1ms, and there-by CMCT was 9.2+/-1.1ms. 2) Latency between head and contralateral AH was 39.0+/-2.6ms, latency between lumbar region and ipsilateral AH was 20.9+/-2.1ms, and there-by CMCT was 1.8+/-2.0ms. 3) Latency was statistically well correlated with subject height, but not CMCT. 4) There was no statistical significance, between male and female, right and left side, among age group, in latency and CMCT. 5) By voluntary muscle contractions, latency was shortened and amplitude was increased on vertex stimulation, but not hanged on stimulation of cervical and lumbar region. 6) By incraesing stimulus intensity, latency was shortened and amplitude was increased on vertex stimulation, but amplitude only was increased on stimulation of cervical region.
Electric Stimulation ; Evoked Potentials, Motor* ; Female ; Foot ; Hand ; Head ; Humans ; Lumbosacral Region ; Male ; Muscle, Skeletal ; Peripheral Nerves ; Reference Values* ; Transcranial Magnetic Stimulation* ; Volunteers

A case of metastatic renal cell carcinoma is reported. The tumor had imaging features of meningioma on brain computerized tomography and magnetic resonance.
Brain ; Carcinoma, Renal Cell* ; Dura Mater* ; Meningioma*

BACKGROUND: Presenteeism refers to the phenomenon of working while sick. Its development can be attributed to not only somatic symptoms but also underlying social agreements and workplace atmosphere. In this study, we analyzed presenteeism among workers from various industries, focusing on job-related stress with stratification on the presence of depression. METHODS: We conducted the study with data from questionnaires filled in by different enterprises enrolled in the Federation of Korean Trade Unions. Workers' depressive symptoms were investigated using the Patient Health Questionnaire-2, while questions on job-related stress and presenteeism were derived from the short form of the Korean Occupational Stress Scale and the official Korean version of the Work-Productivity and Activity Impairment Questionnaire-General Health, respectively. Multilevel logistic analysis was conducted to determine the statistical differences derived from the differences between companies. RESULTS: In total, 930 participants (753 men and 177 women) from 59 enterprises participated in the research. We conducted multilevel logistic regression to determine the association between the variables and presenteeism, with stratification by the presence of depression. Higher job demands and higher interpersonal conflict showed significantly elevated odds ratios (ORs) in univariate models and in the multivariate multilevel model. In the final model of total population, fully adjusted by general and work-related characteristics, higher job demands (OR: 3.29, 95% confidence interval [CI]: 2.08–5.21) and interpersonal conflict (OR: 1.87, 95% CI: 1.29–2.71) had significantly higher ORs—a tendency that remained in participants without depression. CONCLUSIONS: This study reflected the factors associated with presenteeism among workers from various enterprises. The findings revealed that job-related stress was closely related to presenteeism in both the total population and in the population without depression. Thus, it emphasized interventions for managing job stress among workers to reduce presenteeism in general workers' population.
Atmosphere ; Depression ; Humans ; Labor Unions ; Logistic Models ; Male ; Odds Ratio ; Presenteeism

Bacteria ; Bone Regeneration ; Bone Resorption ; Fibroblasts ; Humans ; Maxillary Sinus ; Membranes ; Suture Techniques ; Sutures ; Transplants ; Wound Healing

Aneurysm ; Bone Cysts ; Bone Resorption ; Calcium ; Clavicle ; Diagnosis, Differential ; Facial Bones ; Giant Cells ; Granuloma ; Hyperparathyroidism ; Hyperparathyroidism, Primary ; Mandible ; Maxilla ; Osteoblasts ; Osteoclasts ; Physical Examination ; Ribs

BACKGROUND: Elderly patients visiting pain clinic may be at greater risk of misunderstanding the explanation because of age-related cognitive decline. Video instruction may provide a consistent from of teaching in a visual and realistic manner. We evaluated the effect of educational video on the patient understanding and satisfaction in a group of geriatric patients visiting pain clinic. METHODS: Ninety two patients aged more than 60 years old who were scheduled for transforaminal epidural block were recruited. After exposure to either video or paper instruction process, each patient was asked 5-item comprehension questions, overall satisfaction and preference question. During follow-up period, number of outpatient referral-line call for further explanation was counted. RESULTS: We observed significantly better comprehension in the video education compared with paper instruction (P < 0.001). Patient satisfaction was also higher in the video group (P = 0.015), and patients visiting pain clinic were more preferred video instruction (P < 0.001). Proportion of referral-line call for further explanation were similar (P = 0.302). CONCLUSIONS: Video approach to instruction process before consent improves treatment comprehension in geriatric patient visiting pain clinic.
Aged ; Comprehension ; Follow-Up Studies ; Humans ; Outpatients ; Pain Clinics ; Patient Satisfaction

TNF -related apoptosis inducing ligand (TRAIL) is a member of TNF ligand superfamily. TRAIL transduces death signal through two distinct receptors, TRAILR -1I and TRAILR -2, while the engagement of TRAILR -3 and TRAILR -4 interferes with TRAIL -induced apoptosis. The profile of TRAILR expression has been reported to be a mechanism by which transformed cells undergo apoptosis in response to TRAIL while normal cells do not. Rheumatoid arthritis (RA) is an inflammatory autoimmune disease which is characterized by the hyperplasia of synovial membrane. The dysregulation of apoptosis in synoviocytes has been suggested to contribute to synovial hyperplasia. Synovial fibroblasts obtained from patients with RA have been reported to exhibit several semi - transformed aspects. To investigate whether RA synovial fibroblasts acquire the susceptibility to TRAIL -induced apoptosis, synovial fibroblast lines obtained from 2 RA patients and two osteoarthritis (OA) patients were cultured in the presence of recombinant human TRAIL and followed by MTT assay. TRAIL treatment resulted in a significant decrease in the viability of both lines of RA cells, indicating TRAIL -induced cell death of RA synovial fibroblasts, whereas OA synovial fibroblasts and normal human dermal fibroblasts were either resistant or less sensitive to TRAIL as compared with RA synovial fibroblasts. In RT -PCR analyses, the expression levels of TRAILR 4 in RA synovial fibroblasts were lower than in OA synovial fibroblasts, while other receptors in both cell lines were expressed at comparable levels. Immunohistochemical studies showed that in RA synovial tissues TRAILR -3cells were mainly leukocyte infiltrates, implying that such leukocyte infiltrates play a role in the perpetuation of the disease. Taken together, these results suggest that RA synovial fibroblasts acquire the susceptibility to TRAIL -induced cell death during disease progression and this death signal may be regulated by, at least in part, differential expression of TRAILR -4 molecule.
Apoptosis ; Arthritis, Rheumatoid* ; Autoimmune Diseases ; Cell Death* ; Cell Line ; Disease Progression ; Fibroblasts* ; Humans ; Hyperplasia ; Leukocytes ; Osteoarthritis ; Synovial Membrane