1.A Comparative Study of Therapeutic Effect of Intravenous Gammaglobulin plus Aspirin Versus Aspirin Alone in Kawasaki Syndrome.
Boung Yul LEEM ; Chong Sung CHUNG ; Sung Ho CHA ; Yong Mook CHOI ; Chang Il AHN
Journal of the Korean Pediatric Society 1989;32(10):1408-1415
No abstract available.
Aspirin*
;
Mucocutaneous Lymph Node Syndrome*
2.A study on the changes in attractive force of magnetic attachments for overdenture.
Han Wool LEEM ; In Ho CHO ; Jong Hyuk LEE ; Yu Sung CHOI
The Journal of Advanced Prosthodontics 2016;8(1):9-15
PURPOSE: Although magnetic attachment is used frequently for overdenture, it is reported that attractive force can be decreased by abrasion and corrosion. The purpose of this study was to establish the clinical basis about considerations and long term prognosis of overdenture using magnetic attachments by investigating the change in attractive force of magnetic attachment applied to the patients. MATERIALS AND METHODS: Among the patients treated with overdenture using magnetic attachments in Dankook University Dental Hospital, attractive force records of 61 magnetic attachments of 20 subjects who re-visited from July 2013 to June 2014 were analyzed. Dental magnet tester (Aichi Micro Intelligent Co., Aichi, Japan) was used for measurement. The magnetic attachments used in this study were Magfit IP-B Flat, Magfit DX400, Magfit DX600 and Magfit DX800 (Aichi Steel Co., Aichi, Japan) filled with Neodymium (NdFeB), a rare-earth magnet. RESULTS: Reduction ratio of attractive force had no significant correlation with conditional variables to which attachments were applied, and was higher when the maintenance period was longer (P<.05, r=.361). Reduction ratio of attractive force was significantly higher in the subject group in which attachments were used over 9 years than within 9 years (P<.05). Furthermore, 16.39% of total magnetic attachments showed detachment of keeper or assembly. CONCLUSION: Attractive force of magnetic attachment is maintained regardless of conditional variables and reduction ratio increased as the maintenance period became longer. Further study on adhesive material, attachment method and design improvement to prevent detachment of magnetic attachment is needed.
Adhesives
;
Corrosion
;
Denture, Overlay*
;
Effect Modifier, Epidemiologic
;
Humans
;
Neodymium
;
Prognosis
;
Steel
3.Normal values of Motor Evoked Potentials by Transcranial Magnetic Stimulation.
Ho Geun LEE ; Gook Ki KIM ; Young Jin LIM ; Tae Sung KIM ; Bong Arm RHEE ; Won LEEM
Journal of Korean Neurosurgical Society 1991;20(8):609-620
Electrical stimulation has been used for evaluating central motor system and deep portion of peripheral nerve, but it was painful. And then magnetic stimulation was introduced recently and used widely because it was painless and easily repeated, compared to electrical stimulation. This study was undertaken in order to obtain normal valued of motor evoked potentials by transcranial magnetic stimulation. Ninety-two volunteers, free of neurological disease, were tested with Medelec Magstim model 200 and Medelec MIstral. There were 55 male and 37 female, ranging in height from 130 to 180 centimeter, with a mean height of 165.9 centimeter, in age from 13 to 70 years, with a mean age of 34 years. Transcranial magnetic stimulation cause contralateral hand and foot muscle responses, and the resultant motor evoked potentials can be recorded. Stimulating sites were near vertex in head, Erb's point in cervical region and L45 interspace in lumbar region. Recording sites wre abductor pollicis brevis(APB) in hand and abductor hallucis(AH) in foot. Our results were as follow ; 1) Latency between head and contralateral APB was 20.9+/-1.5ms, latency between cervical region and ipsilateral APB was 11.7+/-1.1ms, and there-by CMCT was 9.2+/-1.1ms. 2) Latency between head and contralateral AH was 39.0+/-2.6ms, latency between lumbar region and ipsilateral AH was 20.9+/-2.1ms, and there-by CMCT was 1.8+/-2.0ms. 3) Latency was statistically well correlated with subject height, but not CMCT. 4) There was no statistical significance, between male and female, right and left side, among age group, in latency and CMCT. 5) By voluntary muscle contractions, latency was shortened and amplitude was increased on vertex stimulation, but not hanged on stimulation of cervical and lumbar region. 6) By incraesing stimulus intensity, latency was shortened and amplitude was increased on vertex stimulation, but amplitude only was increased on stimulation of cervical region.
Electric Stimulation
;
Evoked Potentials, Motor*
;
Female
;
Foot
;
Hand
;
Head
;
Humans
;
Lumbosacral Region
;
Male
;
Muscle, Skeletal
;
Peripheral Nerves
;
Reference Values*
;
Transcranial Magnetic Stimulation*
;
Volunteers
4.Low Grade Astrocytoma-Need Postoperative Radiotherapy or Not?.
Seong Eon HONG ; Doo Ho CHOI ; Tae Sung KIM ; Won LEEM
Journal of the Korean Society for Therapeutic Radiology 1992;10(2):171-180
The precise role of radiotherapy for low grade gliomas including the optimal radiation dose and timing of treatment remains unclear. The information given by a retrosepctive analysis may be useful in the design of prospective randomized studies looking at radiation dose and time of surgical and radiotherapeutic treatment. The records of 56 patients (M:F=29:27) with histologically verified cerebral low grade gliomas(47 cases of grade 1 or 2 astrocytomas and 9 oligodendrogliomas) diagnosed between 1979 and 1989 were retrospectively reviewed. The extent of surgical tumor removal was gross total or radical subtotal in 38 patients(68%) and partial or biopsy only in the remaining 18 patients(32%). Postooperative radiation therapy was given to 36 patients(64%) of the total 56 patients with minimum dose of 5000 cGy (range=1250 to 7220 cGy). The 5-and 10-year survival rates for the total 56 patients were 44% and 32% respectively with a median survival of 4.1 years. According to the histologic grade the 5- and 10-year survivals were 52% and 35% for the 24 patients respectively with grade I astrocytomas compared to 20% and 10% for the 23 patients with grade II astrocytomas. Survival of oligodendroglioma patients was greater than those with astrocytoma (65% vs 36% at 5 years), and the difference was also remarkable in the long term period of follow up (54% vs 23% at 10 years). Those who received high-dose radiation therapy (> or =5400 cGy) had significant better survival than those who received low-dose radiation(< 5400 cGy) or surgery alone (p<0.05). The 5-and 10-year survival rates were, respectively 59% and 46% for the 23 patients receiving high-dose radiation, 36% and 24% for the 13 patients receiving low-dose radiation, and 35% and 26% for the 20 patients with surgery alone. Survival rates by the extent of surgical resection were similar at 5 years (46% vs 41%), but long term survival was quite different (p<0.01) between total/subtotal resection and partial esection/biopsy (41% and 12%, resepctively). Previously published studies have identified important prognostic factors in these tumor : age, extent of surgery, grade, performance status, and duration of symptoms. But in our cases statistical analysis revealed that grade I histology (p<0.025) and young age (p<0.001) were the most significant good prognostic variables.
Astrocytoma
;
Biopsy
;
Brain Neoplasms
;
Follow-Up Studies
;
Glioma
;
Humans
;
Oligodendroglioma
;
Radiotherapy*
;
Retrospective Studies
;
Survival Rate
5.Renal Cell Carcinoma Metastatic to the Dura Mater Simulating a Meningioma: A Case Report.
Ho Geun LEE ; Young Jin LIM ; Tae Sung KIM ; Gook Ki KIM ; Bong Arm RHEE ; Won LEEM
Journal of Korean Neurosurgical Society 1992;21(7):865-872
A case of metastatic renal cell carcinoma is reported. The tumor had imaging features of meningioma on brain computerized tomography and magnetic resonance.
Brain
;
Carcinoma, Renal Cell*
;
Dura Mater*
;
Meningioma*
6.Association between job-related stress and experience of presenteeism among Korean workers stratified on the presence of depression
Jihyun KIM ; Yeong Kwang KIM ; Sung Ho LEEM ; Jong Uk WON
Annals of Occupational and Environmental Medicine 2019;31(1):e26-
BACKGROUND: Presenteeism refers to the phenomenon of working while sick. Its development can be attributed to not only somatic symptoms but also underlying social agreements and workplace atmosphere. In this study, we analyzed presenteeism among workers from various industries, focusing on job-related stress with stratification on the presence of depression. METHODS: We conducted the study with data from questionnaires filled in by different enterprises enrolled in the Federation of Korean Trade Unions. Workers' depressive symptoms were investigated using the Patient Health Questionnaire-2, while questions on job-related stress and presenteeism were derived from the short form of the Korean Occupational Stress Scale and the official Korean version of the Work-Productivity and Activity Impairment Questionnaire-General Health, respectively. Multilevel logistic analysis was conducted to determine the statistical differences derived from the differences between companies. RESULTS: In total, 930 participants (753 men and 177 women) from 59 enterprises participated in the research. We conducted multilevel logistic regression to determine the association between the variables and presenteeism, with stratification by the presence of depression. Higher job demands and higher interpersonal conflict showed significantly elevated odds ratios (ORs) in univariate models and in the multivariate multilevel model. In the final model of total population, fully adjusted by general and work-related characteristics, higher job demands (OR: 3.29, 95% confidence interval [CI]: 2.08–5.21) and interpersonal conflict (OR: 1.87, 95% CI: 1.29–2.71) had significantly higher ORs—a tendency that remained in participants without depression. CONCLUSIONS: This study reflected the factors associated with presenteeism among workers from various enterprises. The findings revealed that job-related stress was closely related to presenteeism in both the total population and in the population without depression. Thus, it emphasized interventions for managing job stress among workers to reduce presenteeism in general workers' population.
Atmosphere
;
Depression
;
Humans
;
Labor Unions
;
Logistic Models
;
Male
;
Odds Ratio
;
Presenteeism
9.Treatment Outcome of Gamma Knife Radiosurgery for GH-Secreting Pituitary Tumors.
Young Jin LIM ; Yeong Ho CHOI ; Won LEEM ; Ki Taek LEE ; Jun Seok KOH ; Tae Sung KIM ; Gook Ki KIM ; Bong Arm RHEE
Journal of Korean Neurosurgical Society 2001;30(5):567-574
OBJECTIVE: As for growth hormone(GH) secreting pituitary adenoma, it's remission should be declared on the basis of satisfactory controlling of the tumor, normalization of hormonal level, and symptomatic improvement of the patient. Several modalities of treatment have been applied and administered, and yet, this disease still remains as inveterate one to be fully treated. The purpose of this study is to evaluate the outcome of gamma knife radiosurgery(GKRS) for GH secreting pituitary adenoma, and to identify various factors affecting the outcome of the treatment. METHOD: A group of 24 out of 35 patients, treated by Leksell gamma knife unit during the period of March of 1992 through October of 1997, had been observed for more than two years. The mean target volume of microadenoma was 449.3mm3(range 216-880mm3), and that of macroadenoma was 3183.1mm3(range 1456-13125mm3). The tumor margin was covered with 50% isodose profile, and mean marginal dose was 25.2Gy(range 15-32.4Gy). The mean number of isocenter was 4.3(range 1-6). The exposed dose to the optic apparatus was less than 8Gy. The mean follow-up period was 37.8months(range 24-102months). RESULT: No patients showed any increase in the tumor volume during the follow-up period. And definite shrinkage of tumor volume(tumor volume reduction rate, TVRR: more than 50%) was obtained in 10 patients(41.7%). Twenty one patients(87.5%) had reduced hormonal level compared than pre-treatment level. Among them, normalization of the hormonal level was achieved in 12 patients(50%). Clinicoendocrinological remission was seen in 3 patients (12.5%). According to the results of statistical analysis, tumor volume(p=0.016),duration of symptoms(p=0.046), initial GH level(p=0.017), and the invasion of cavernous sinus(p=0.036) were significantly favorable to post-radiosurgical outcome. The TVRR was significantly related to post-radiosurgical reduction of serum GH level. Permanent complication was not seen. CONCLUSION: The authors concluded that GKRS is a safe and effective treatment modality for acromegaly. To otain the better outcome of GKRS in GH secreting pituitary adenoma, more careful and sophisticated treatment-planning is recommended.
Acromegaly
;
Follow-Up Studies
;
Growth Hormone
;
Growth Hormone-Secreting Pituitary Adenoma
;
Humans
;
Pituitary Neoplasms*
;
Radiosurgery*
;
Treatment Outcome*
;
Tumor Burden
10.Ependymal Cyst: A Case Report.
Tae Ho CHUN ; Gook Ki KIM ; Hyung Doo KIM ; Young Jin LIM ; Tae Sung KIM ; Bong Arm RHEE ; Won LEEM
Journal of Korean Neurosurgical Society 1995;24(12):1577-1582
The authors report a case of a large symptomatic ependymal cyst in a 3-year-old boy not in communication with the subarachnoid space or the ventricular system, resulting in compression of the lateral ventricle and the surrounduing structures. Computerized tormography(CT) of the boy who complained of intermittent headache since a year ago revealed a large-sized, low density mass at the left parieto-occipital region of the brain. The cyst was totally removed, and histopathological study of the evacuated mass showed that the cyst wall was composed of ciliated columnar and cuboidal epithelium with thin collagenous membrane. Postoperatively, the patient recovered unremarkably with no neurological deficits and was discharged with complete relieval of his symptoms. The histogensis and the histopathological features are discurssed in the context of the review of the literature.
Brain
;
Child, Preschool
;
Collagen
;
Epithelium
;
Headache
;
Humans
;
Lateral Ventricles
;
Male
;
Membranes
;
Subarachnoid Space