No abstract available.
Humans

No abstract available.

No abstract available.
Muscular Dystrophy, Oculopharyngeal*

Radiation effect on mammals, especially on hematologic changes, has been studied since discovery of x-ay. Various experimental animals were tried for radiobiological studies. 72 hybrid mice with conventional ffaction (5X/week), large abdominal field (2 x3cm, from symphysis pubic to xyphoid process) were used. Body weight was declined gradually by increasing irradiation doses, nadir was about 29.7% in male ; 30.4% in female at 6000 rad irradiation group. Hemoglobin value was nearly normal throughout entire treatment. Significant dropping of WBC count was noted to 40-0% of pretreatment values by only 1000 rad irradiation. Change of differential count was interesting; lymphocyte proportion showed gradual reduction, instead of gradual increasing of segmented neutrophil. Those proportion were reversed after 6000 rad irradiation. Urinary protein tests showed + - +++, showing no correlation with dosage. Application. of our study in clinical combination therapy (radiation + chemotherapy) was discussed.
Animals ; Body Weight* ; Female ; Humans ; Lymphocytes ; Male ; Mammals ; Mice* ; Neutrophils ; Radiation Effects*

Anisakiasis refers to the infestation of humans by species of marine nematode larvae belonging to the subfamily Anisakiae. An acute abdominal symptom may occur after ingestion of raw marine fish containing nematode larvae of the genus Anisakis. Migration of the parasite into the wall of gtomach, small intestine or, less commomly, the colon elicits a striking eosinophilic granulomatous tissue response. A 39 year old man was visited St. Vincent Hospital because of abdominal distension and tenderness. The plain abdominal X-ray showed ileus pattern suggesting intestinal obstruction. Hence we presented a case of intestinal Anisakiasis combined with intstinal obstruction.
Adult ; Anisakiasis* ; Anisakis ; Colon ; Eating ; Eosinophils ; Humans ; Ileus ; Intestinal Obstruction ; Intestine, Small ; Larva ; Parasites ; Strikes, Employee

No abstract available.
Classification* ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive*

OBJECTIVE: The purpose of this study was to investigate the prognosis of pregnancy and perinatal outcomes of epileptic women used antiepileptic drugs. METHODS: A retrospective analysis of 66 consecutive pregnancies of 41 epileptic women from January 1989 through December 2005 was performed. The maternal and perinatal outcomes of pregnancies with epilepsy were compared with those of 1,000 normal pregnancies of similar age and parity occurred during the same period. We also compared the perinatal outcomes regarding protocol of antiepileptic drugs (monotherapy vs polytherapy), existence of gestational seizure, and duration of epileptic history. Statistical analyses with chi-square test and t-test were performed. RESULTS: In our comparison study between epilepsy and normal groups, with the exception of primigravida (43.8% vs 31.8%, p=0.009), induction of labor (43.1% vs 22.1%, p=0.001) and major congenital malformation (6.9% vs 2.0%, p=0.015), no other significant differences regarding maternal and perinatal outcomes were noted between two groups. There were no different obstetrical outcomes between monotherapy and polytherapy groups. In epileptic women with gestational seizure, the rate of fetal distress (20.0% vs 2.3%, p=0.02) was significantly increased. In longer epileptic history (> or =10 years), the rates of preterm birth, low birth weight, and major congenital malformation were increased, but there was no statistical significance. CONCLUSION: There are no increased maternal and perinatal complications in epileptic women used antiepileptic drugs, except for major congenital malformation.
Anticonvulsants* ; Epilepsy ; Female ; Fetal Distress ; Humans ; Infant, Low Birth Weight ; Infant, Newborn ; Parity ; Pregnancy* ; Pregnant Women* ; Premature Birth ; Prognosis* ; Retrospective Studies ; Seizures

OBJECTIVE: To compare the effectiveness of oral misoprostol with vaginal misoprostol administration in mid-trimester pregnancy termination after pretreatment with serial laminarias tenting. METHODS: This study was made in 50 patients for mid-trimester pregnancy termination at Department of Obstetrics and Gynecology, Chonbuk National University Hospital from January 1999 through December 2002. Twenty five women received misoprostol orally in a dose of 200 micro gram every hour for 3 doses followed by 400 micro gram every 4 hours after serial laminarias tenting. Twenty five women received misoprostol vaginally in a dose of 400 micro gram every 4 hours after serial laminarias tenting. Side effects of drug, induction to delivery interval, delivery numbers within 24 hours, curettage numbers for retained placenta, and the length of hospital stay were compared. RESULTS: The mean time of induction to delivery interval was significantly shorter in the vaginal group (15.5 +/- 12.7 vs 24.2 +/- 14.3 hours, p<0.01). The length of hospital stay was also shorter in the vaginal group (38.9 +/- 13.1 vs 47.2 +/- 14.5 hours, p<0.01). The number of patients delivered within 24 hours was more in the vaginal group (92 vs 72%, p<0.05). The side effects of misoprostol were slightly more common in the oral group than the vaginal group without statistical significance. CONCLUSION: We suspect that after serial tenting of laminarias, intravaginal misoprostol appears to be more safe and effective than oral misoprostol for mid-trimester termination.
Curettage ; Female ; Gynecology ; Humans ; Jeollabuk-do ; Laminaria ; Length of Stay ; Misoprostol* ; Obstetrics ; Placenta, Retained ; Pregnancy*

BACKGROUND: Endotracheal suctioning is associated with complications that include bleeding, infection, hypoxemia, cardiovascular instability, and tracheal mucosal injury. Recently, a closed-suction catheter with a pressure valve (Acetrachcare, AceMedical Co., Republic of Korea) was developed. We hypothesized that this new catheter might reduce tracheal mucosal injury compared to a conventional closed-suction catheter (Trachcare, Kimberly-balla RD, USA). METHODS: This prospective, randomized study enrolled medical and surgical patients who required mechanical ventilation for more than 48 hours. Patients were randomized into two groups: one group was suctioned with the conventional closed-suction catheter (CCC) and the other group was suctioned with the closed-suction catheter with pressure valve (CCPV). Bronchoscopy was performed 48 hours later, and the severity of tracheal mucosal injury was graded on a 5-point scale, as follows: 0 = normal; 1 = erythema or edema; 2 = erosion; 3 = hemorrhage; and 4 = ulceration or necrosis. RESULTS: A total of 76 patients (37 with CCPV and 39 with CCC) were included. There were no significant differences between the groups regarding demographic characteristics, changes in hemodynamic parameters during suction, incidence of pneumonia, length of intensive care unit (ICU) stay, or ICU mortality. On bronchoscopic evaluation, the use of the CCPV led to a significant decrease in tracheal mucosal injury (median tracheal mucosal injury grade 1 [IQR 0-1] vs. 2 [IQR 1-3], p = 0.001). CONCLUSIONS: We conclude that the novel closed-suction catheter with pressure valve may reduce tracheal mucosal injury compared to conventional catheters.
Anoxia ; Bronchoscopy ; Catheters* ; Edema ; Erythema ; Hemodynamics ; Hemorrhage ; Humans ; Incidence ; Intensive Care Units ; Mortality ; Necrosis ; Pneumonia ; Prospective Studies ; Respiration, Artificial ; Suction ; Ulcer

Even though the mechanism and the nature of radiation induced pneumonitis, esophagitis and gastroenteritis were detailed by many authors, complicated secondary infection is still serious problem, sometimes fatal, even today. We experience a case of multiple pyogenic abscess in subcutaneous tissue of the back and both kidneys which could not differenciate from multiple metastatic sarcoma grossly, and report with review of literatures, lab. findings.
Abscess* ; Animals ; Coinfection ; Esophagitis ; Gastroenteritis ; Kidney ; Mice* ; Pneumonia ; Sarcoma ; Subcutaneous Tissue