1.Intra-abdominal Angiosarcomatosis Induced by Irradiation.
Hee Jin CHANG ; Youn Joo KIM ; Sung Eun YANG ; Sung Sook PAENG ; Jung Il SUH
Korean Journal of Pathology 1997;31(3):269-274
Therapeutic irradiation can induce angiosarcoma. Radiation-induced angiosarcoma constitutes 20% of all angiosarcomas. Although its common site of origin is the skin and subcutaneous tissue, it rarely arises in small or large bowels with a presentation as multifocal abdominal angiosarcomatosis. We report a case of intra-abdominal angiosarcomatosis involving the jejunum, ileum, transverse colon, mesentery and right ovary in a 63-year-old female. It developed 10 years after therapeutic irradiation for squamous cell carcinoma of uterine cervix. She developed panperitonitis due to intestinal perforation. She died from sepsis 3 days after segmental resection of the small bowel and right oophorectomy. We reviewed the previously reported cases and describe the clinicopathologic features of this tumor.
Carcinoma, Squamous Cell
;
Cervix Uteri
;
Colon, Transverse
;
Female
;
Hemangiosarcoma
;
Humans
;
Ileum
;
Intestinal Perforation
;
Jejunum
;
Mesentery
;
Middle Aged
;
Ovariectomy
;
Ovary
;
Sepsis
;
Skin
;
Subcutaneous Tissue
2.Purturbation of Th1 / Th2 Balance by Interleukin 4 Receptor alpha Variant Q576R in Rheumatic Disease.
Sung Hee HWANG ; Jee Hee YOUN ; Chul Soo CHO ; Jun Ki MIN ; Wan Uk KIM ; Sung Hwan PARK ; Ho Youn KIM
Korean Journal of Immunology 2000;22(1):9-15
No abstract available.
Interleukin-4*
;
Interleukins*
;
Receptors, Interleukin-4*
;
Rheumatic Diseases*
3.Graves' disease complicating pregnancy.
Sung Soo KIM ; Bo Hyun YOON ; Bo Youn CHO ; Hee Chul SYN ; Syng Wook KIM
Korean Journal of Perinatology 1991;2(1):105-113
No abstract available.
Graves Disease*
;
Pregnancy*
4.Fatal Craniofacial Injury by an Angle Grinder.
Ji Youn SUNG ; Sohyung PARK ; Hongil HA
Korean Journal of Legal Medicine 2009;33(1):45-49
A death due to angle grinder injuries is reported. An angle grinder is a widely used electronic device at a working place or at home. A deceased old man and an angle grinder without a protective guard were found at the living room in his house where he had been renovating. The wound of the victim's head showed an oblique laceration, skull fractures and tearing on the brain, embedded with grinder disk fragments. A small intraparenchymal hematoma was in the midbrain, which could be the cause of the fall leading to the accident. Disreard of the cause of the accident, the absence of a protective guard and removal of one hilt might have contribute to the death of the victim.
Brain
;
Electronics
;
Electrons
;
Head
;
Hematoma
;
Hypogonadism
;
Lacerations
;
Mesencephalon
;
Mitochondrial Diseases
;
Ophthalmoplegia
;
Skull Fractures
5.The Reliability and Validity of Patient-Generated Subjective Global Assessment (PG-SGA) in Stroke Patients.
Sung Hee YOO ; Eui Guem OH ; Mi Jung YOUN
Journal of Korean Academy of Adult Nursing 2009;21(6):559-569
PURPOSE: This study was to examine the reliability and validity of Patient-Generated Subjective Global Assessment (PG-SGA) as a nutritional measurement for stroke patients. METHODS: This was a methodological study performed from May 6 to June 10, 2009 at a tertiary university hospital in Seoul. For reliability of PG-SGA, inter-rater reliability was used for statistics. For concurrent validity, BMI and biomarkers were compared between PG-SGA 0 ~ 8 and > or = 9. In addition, sensitivity, specificity, and predictive value of PG-SGA compared with SGA were calculated using a contingency table. For predictive validity, hospital day, complications, and readmission within 1-month after discharge were compared between PG-SGA 0 ~ 8 and > or = 9. RESULTS: Correlation of PG-SGA score between two observers was 0.83, and kappa value for the agreement of severe malnutrition was 0.78(all p(s) < .001). The scored PG-SGA showed high sensitivity and specificity (100% and 96.7%, respectively). Severe undernourished patients (PG-SGA > or = 9) had significantly low TLC, protein, albumin, and prealbumin (all p(s) < .01) compared with non-undernourished patients (PG-SGA 0 ~ 8). Also, in severe undernourished patients, complications and readmission (all p(s) = 0.01) were more often represented, and hospital days (p = .013) were significantly delayed. CONCLUSION: PG-SGA is a reliable and valid measurement to assess nutritional status for stroke patients.
Biomarkers
;
Humans
;
Malnutrition
;
Nutrition Assessment
;
Nutritional Status
;
Prealbumin
;
Reproducibility of Results
;
Sensitivity and Specificity
;
Stroke
6.Morphologic changes and morphology score of red blood cells stored in CPDA-1.
Sung Hee LEE ; Tae Youn CHOI ; Won Bae KIM ; Duk Yong KANG ; Young Chul OH
Korean Journal of Blood Transfusion 1993;4(1):49-53
No abstract available.
Erythrocytes*
7.Clinicopathological Significance of Invasive Ductal Carcinoma with High Prevalence of CD44(+)/CD24(-/low) Tumor Cells in Breast Cancer.
Ji Youn SUNG ; Gou Young KIM ; Yong Koo PARK ; Juhie LEE ; Youn Wha KIM ; Sung Jig LIM
Korean Journal of Pathology 2010;44(4):390-396
BACKGROUND: Epithelial tumor cells with a CD44(+)/CD24(-/low) immunoprofile may have the ability to cause breast cancer. We studied these cells and their clinicopathological significance. METHODS: The clinicopathologic findings of 100 invasive ductal carcinoma (IDC) cases and 45 ductal carcinoma in situ (DCIS) cases were reviewed. CD44(+)/CD24(-/low) tumor cells were identified by immunohistochemistry, and their clinicopathological implications in IDC and DCIS were analyzed. RESULTS: IDC with a high prevalence of CD44(+)/CD24(-/low) tumor cells was significantly associated with larger mass, higher grade, estrogen receptor (ER) negativity, and tumor cells with a higher frequency of metastasis. The proportion of CD44(+)/CD24(-/low) tumor cells in IDC, and its DCIS components was not significantly different, whereas the proportion of CD44(+)/CD24(-/low) tumor cells was higher in DCIS than in the DCIS component of IDC (p < 0.001). CONCLUSIONS: IDC with a high prevalence of CD44(+)/CD24(-/low) tumor cells might correlate with aggressive features, such as ER and higher grades. Moreover, the proportion of CD44(+)/CD24(-/low) tumor cells in the DCIS components of IDC and DCIS might harbor different biology, which may lead to differences in cancer progression and early carcinogenesis.
Antigens, CD24
;
Antigens, CD44
;
Biology
;
Breast
;
Breast Neoplasms
;
Carcinoma, Ductal
;
Carcinoma, Intraductal, Noninfiltrating
;
Estrogens
;
Immunohistochemistry
;
Neoplasm Metastasis
;
Neoplastic Stem Cells
;
Prevalence
8.Papillary Carcinoma of the Thyroid Gland with Nodular Fasciitis-like Stroma.
Ki Yong NA ; Hyun Soo KIM ; Ji Youn SUNG ; Won Seo PARK ; Youn Wha KIM
Korean Journal of Pathology 2013;47(2):167-171
Papillary thyroid carcinoma with nodular fasciitis-like stroma (PTC-NFS) is a rare variant of PTC. The term 'PTC with fibromatosis-like stroma' has been used as a synonym to describe this variant. It is characterized by extensive proliferation of fibroblasts and myofibroblasts in the tumor stroma, which occurs in up to 80% of the tumors. We herein describe a case of PTC-NFS which developed in a 49-year-old woman with the demonstration of findings of ultrasonography, fine needle aspiration cytology and histological examination of the lesion. To characterize the stromal components, we investigated the expression of several immunohistochemical markers which have been shown to be expressed differently in nodular fasciitis (NF) and fibromatosis (FM). The immunostaining results demonstrated nuclear and cytoplasmic accumulation of beta-catenin, cytoplasmic transforming growth factor-beta expression and nuclear Smad expression in the stromal cells, suggesting that the stromal cells in this case have similar molecular profiles to those of FM rather than NF.
beta Catenin
;
Biopsy, Fine-Needle
;
Carcinoma
;
Carcinoma, Papillary
;
Cytoplasm
;
Factor IX
;
Fasciitis
;
Female
;
Fibroblasts
;
Fibroma
;
Humans
;
Myofibroblasts
;
Stromal Cells
;
Thyroid Gland
;
Thyroid Neoplasms
9.Evaluation of Skin Surface Hydration in Diabetic Patients Using a Hydrometer and Corneometer.
Seok Beom PARK ; Sung Duck KIM ; Chun Sik YOUN ; Dae Hun SUH ; Hee Chul EUN ; Jai Il YOUN ; Chan Soo SHIN
Korean Journal of Dermatology 1999;37(3):311-319
BACKGROUND: Diabetes mellitus is a common condition, and the majority of patients have one or more cutaneous complications. Among them, xerosis is well known to be closely related to diabetics. The xerosis is inversely reflected upon skin surface hydration, the state of which can be exactly assessed with various investigating instruments, such as a hydrometer and corneometer. OBJECTIVE: Our purpose was to compare the hydration state of diabetics with normal persons by the use of a corneometer and hydrometer. METHODS: A total of 267 diabetics were asked whether they felt xerosis or pruritus. In a subgroup of 31 patients, the water content was evaluated and compared by the parameters of diabetic severity. Forty-one non-diabetics were selected for the normal control.
Diabetes Mellitus
;
Humans
;
Pruritus
;
Skin*
;
Water
10.Epidermoid Cyst of the Cecum.
Jae Young PARK ; Youn Wha KIM ; Kil Yeon LEE ; Ji Youn SUNG
Annals of Coloproctology 2015;31(1):37-39
An epidermoid cyst of the cecum is extremely rare; only eight cases have been reported in the literature. A 63-year-old woman was admitted to Kyung Hee University Medical Center with a colonic mass that had been discovered incidentally during a regular health check-up. The radiographic impression was that this mass was a gastrointestinal stromal tumor. During surgery, an exophytic mass in the cecal wall was resected by using an ileocecectomy. Based on the macroscopic and the microscopic findings, this case was identified as an epidermoid cyst of the cecal wall. We report this case to discuss the origin of this entity and the unusual nature of our case.
Academic Medical Centers
;
Cecum*
;
Colon
;
Epidermal Cyst*
;
Female
;
Gastrointestinal Stromal Tumors
;
Humans
;
Middle Aged