The parents have much expectation upon the pregnancy and child birth, and in most cases, they expect the healthy parturient child. However, we can be placed on the high-risk conditions which have the physical, social and immature infant, due to the unexpected results, among the new-born. Accordingly, these high-risk newborn and premature infants will be mostly in NICU, which the concentrated medical treatment can be given, upon their conditions. After their birth and during these periods, they will be divided from the parents, and the nurse will accomplish the bringing-up activities which they can take care of the infant, expected by the parents after their birth. The hospitalization of high-risk newborn including these premature infants is the shocking experience to the parents of family, and thus they can feel the fear and uneasiness, and these reactions of parents are troubled in the behavior at the usual days, and cause the disorder and spiritless status, and these results break the supporting ability of parents, and cause the obstruction. Also, the unavoidable division between the parents and the children as like hospitalization of children can make the parents to feel the alienation emotionally, and this causes the results which the pride on the bringing-up ability of baby gets to be lost. These problems can cause the difficulties on the bonding or the parenting in the further days, and can be related to the neglect and abuse of children. Also, it is gradually increased to study and report which the emotional division by the physical division between the mother and the baby obstructs the normal affection course between the parent and the infant. The stress caused by the birth and the hospitalization of high-risk newborn, as like this, is important in the points which it can uncertainly affect the potential energy for the relationship of parent-child who are finally healthy. Accordingly, the significance and purpose of this study are to understand the contents and degree of stress which the parents of high-risk newborn including the immature child can be experienced from the hospitalization of ICU for their new borns, and thus to offer the basic program to the nursing intervention program for these. The subject of this study is the mother of newborn in NICU of 10 General Hospitals located at the zone of Pusan, Korea from September 1997 to October 1997, and thus makes the subject of 95 person of parents who agreed to take part in the study and it is descriptive study related to the stress of mother having the newborn in NICU. The method is based on the preceding study related to the stress of mother having the experience of child hospitalization and chronic disease child, and then acquires the advice of specialists group as like 5 nursing professors, and then is amended and supplemented. Total number of questions in 43 items and consists of 5 factors as like medical treatment&nursing procedures, disease status&prognosis, role of parents, communication&inter-personal relationships, hospital environment, and is 5 point Likert Scale. The reliability of this study method is very highly shown to be Cronbach alpha=0.95. The collected data is analysed as Average, Frequency, Standard Deviation, T-test, ANOVA, Pearson Correlation Coefficient, Duncan multiful-range test by use of SPSS/PC (V7.5). The results of this study is summarized as under : 1. Every characteristics of subject is which the party of mother is 28.70age(+/-7.48) in the average ages, 51% in the high-school graduate, 38.5% in the christianity, total monthly income is 212.55 thousand won(+/-1.971), 74.5% in the housewife, 72.9% in the parents and children together living and the number of children to be 1.48 person(+/-0.6) in average, the recognition on the prognosis of baby is 74.0% in "Don't know", the relationship with the husband after the hospitalization of baby is 37.3% in "More Intimate", the relationship with the family of husband to be 48% in "No-change", and the degree which is consulted with the husband about the baby is 55% in "very frequently" and the visiting number per week is 4.59(+/-1.63) in average and the accompanying person in the time of visiting is which is which the number of husband is 56.3% and thus is the highest. The characteristics of baby is which the age is 21. 88days(+/-16.47) after the birth in average, the sex to be 50 person in the female 52.1% and the order of birth to be 54.2% in the first child, and the weight in the birth to be 2770gm(+/-610) and the height in the birth to be 46.26cm(+/-7.62) in average. The medical diagnosis is 37.5% in the premature infant, the career of hospitalization is 96.9% in "None", and the operation plan is 90.6% in "None" and the execution of operation is 88% in "None" and the nursing of incubator is 55.2% in "Yes", and the method of feeding is 50.5% in "Oral" and the contents of feeding is 46.9% in the "Milk". 2. The total stress degree of subject is almost highly shown to be as 3.36(+/-0.86). If it is compared upon each cause, 'stress on disease status&prognosis' is highest 3.79(+/-1.28), and it is in the order of 'stress on medical treatment&nursing procedures' 3.70(+/--.93), 'stress on hospital environment' 3.14(+/-0.86), 'stress on role of parents' 3.18(+/-0.92) and 'stress on communication&inter personal relationship' 2.62(+/-0.77). 3. As the results of checking the notworthiness of stress degree upon each variable of subject, the variable showing the noted difference was the birth weight)gamma=-0.16, P=0.04), birth height(gamma=-0.23, P=0.03), nursing in the incubator(F=8.93, P=0.04), feed method(F=2.94, P=0.04). That is to say, it is shown which the smaller the birth weight is, the higher the stress degree of mother is noteworthily. Also, the smaller the birth weight is, the higher the stress degree of mother is noteworthily. Also, the smaller the birth height baby is, the higher the stress of mother is. In the incubator, it is shown which the mother whose baby is nursing in the incubator is higher in the stress degree than other mothers. Upon the feeding method of baby, that is to say, TPN is the highest, and it is shown in the order of NPO, Tube feeding, and P.O. feeding. When we review the above-mentioned results, as the status is serious, it is thought which we include the supporting nursing for coping with the stress of parents in the setting-up od nursing plan for the baby in the NICU.
Birth Weight ; Busan ; Child ; Christianity ; Chronic Disease ; Diagnosis ; Emigrants and Immigrants ; Enteral Nutrition ; Feeding Methods ; Female ; Hospitalization ; Hospitals, General ; Humans ; Incubators ; Infant ; Infant, Newborn ; Infant, Premature ; Intensive Care, Neonatal* ; Korea ; Mothers* ; Nursing ; Parenting ; Parents ; Parturition ; Pregnancy ; Prognosis ; Shock ; Specialization ; Spouses ; Child Health

Most glomerular lesions are associated with qualitative and quantitative alterations of the extracellular matrix components, having relation to progressive glomerular sclerosis. We aimed to investigate the characteristic alteraltions in distribution of extracellular matrix components, such as fibronectin, laminin, collagen type III and IV in human glomerular diseases by immunohistochemical method. The materials included are 3 nephrectomy as normal control, 51 renal biopsies and I autopsy; 3 normal, 5 minimal change disease, 5 minimal change disease with minimal mesangial lgA deposit, 5 benign recurrent hematuria, 10 focal segmental glomerulosclerosis, 15 lgA nephropathy, 10 membranoproliferative glomerulonephritis, 2 diffuse mesangial sclerosis of infancy. Type IV collagen and laminin were present normally in the mesangium, GBM, TBM and interstitial vessels, and were increased at the portion of increased mesangial matrix, of sclerosis and thickened GBM in cases of lgA nephropathy, membranoproliferative glomerulonephritis, focal segmental glomrulosclerosis and diffuse mesangial sclerosis in the proportion to the glomerular damage. Type III collagen was absent in the normal glomeruli, but was detectable focally and segmentally in cases of membranoproliferative glomerulonephritis, IgA nephropathy and focal segmental glomerulosclerosis at the sclerotic portion. Fibronectin was normally detectable mainly in the mesangium, and partly and incompletely in GBM, and was increased at the portion of increased mesangial matrix, sclerosis and thickened GBM in cases of focal segmental glomerulosclerosis, membranoproliferative glomerulonephritis, IgA nephropathy and diffuse mesangial sclerosis, but was diminshed at the old slcerotic portion or global sclerosis. The expression of these antibodies in cases of minimal change disease, minimal change disease with minimal mesangial IgA deposit, benign recurrent hematuria was not different, quantitatively and qualitatively, from that of normal glomeruli. These findings suggest that progressive glomerular sclerosis was due to the increase of extraceuular matrix components such as type IV collagen, laminin, fibronectin and new appearance of type III collagen, and the expression was in proportion to the degree of sclerosis, but had no relation to the disease entity.
Humans ; Biopsy

No abstract available.
Job Satisfaction*

No abstract available.
Job Satisfaction*

The purpose of this study was to identify the incidence of urinary incontinence of elderly women in Korea, to identify the life style for urinary incontinence. The sample consisted of 237 women of Seoul and 5 Provinces. Data for this study was collected from January 16 to June 23 by structured questionnaire. Urinary Symptom Questionnaire developed by Jackson and demographic questionnaire were used to collect the data. The data was analyzed by frequency, percentage, Chi-Square test, Chronbach alpha coefficient with SPSS/PC+ program. 1. It was reported that 64.5% of the subjects have experienced urinary incontinence. And stress, urge, and mixed type incontinence was 34.0%, 8.5%, 57.5% respectively. 2. Characteristics related to urinary incontinence are : Daily frequency 28.7%, nocturia 71.5%, urgency 74.0%, bladder pain 36.7%, unexplained incontinence 35.1%, noctural incontinence 23.5%, frequency of incontinence 23.3%. Wearing protection 42.3%, changing outer clothing 31.0%, hesitancy 17.1%, straining 24.7%, intermittent stream 27.2%, abnormal strength of stream 28.4%, retention 13.6%, burning 5.0%, incomplete emptying 13.6%, Inability to stop mid stream 32.5%. 3. The life style and incidence with urinary incontinence were as following. Fluid intake restriction 18.6%, interference in daily task 30.3%, avoidance of places and situation 28.0%, interference in physical activity 22.3%, interference in relationship with other people 16.6%, interference in relationship with husband/companion 4.5%, time after attack of urinary symptoms 81.5%. In terms of the feeling about the rest of life with urinary symptom, perfectly happy 5.0%, pleased 10.6%, mostly satisfied 18.7%, mixed feelings 28.6%, mostly dissatisfied 20.1%, very unhappy 16.8%, desperate 0.3%. 4. Significant relation between incidence of urinary incontinence and life style. Significant differences between Fluid intake restriction(X2=8.876, P=0.002), affected daily task(X2=32.113, P0.000), avoidance of places and situation(X2=30.155, P=0.000), interference in physical activity(X2=30.209, P=0.000), interference in relationship with other people(X2=26.091, P=0.000). In terms of the feeling about the rest of life with urinary symptom(X2=43.425, P=0.000) of life style and incidence of urinary incontinence. In conclusion, this study were preliminary study to provide nursing practices guidelines for elderly urinary incontinence. Nurses working with elderly should develop and provide adequate care for the incontinent elderly subjects.
Aged* ; Burns ; Clothing ; Female ; Humans ; Incidence* ; Korea ; Life Style ; Motor Activity ; Nocturia ; Nursing ; Quality of Life* ; Rivers ; Seoul ; Urinary Bladder ; Urinary Incontinence* ; Surveys and Questionnaires

BACKGROUND: Several keratolytic agents have been used in many dirmatologic conditions such as callus, keratosis palmaris of plantaris, however the evaluation method of the effects of keratolytiic agents has not been good enough in clinical use. OBJECT: We have conducted an investigation to measure the effect of several keratolytic agents using an in vitro model. METHOD: We measured the fegraded protein of keratin by the bui iet method after adding enzymes such as trypsin, pepsin and papain, and irritants, salicylic acid and sodii m lauryl sulfate to the collected callus. RESULT: The order of the keratolytic effect of the enzymes was trypsir >pepsin>papain. It was difficult to detect the keratolytic effect of salicylic acid becaues of color hiidrance and there was an increasing tendency of keratolyti effect of sodium lauryl sulfate, however it was prominent mainly at a high concentration. CONCLUSION: These results suggested that the potency of similar types of keratolytic enzymes such as pepsin, trypsin and papain can be possible. However it was not such a sitable model to check the potency of the keratolytic effect of salicylic acid and the eoncentration tevel may be an important factor for certain kinds of chemicals such as sodium lauryl sulfate.
Bony Callus ; Irritants* ; Keratolytic Agents ; Keratosis ; Papain ; Pepsin A ; Salicylic Acid ; Sodium Dodecyl Sulfate ; Trypsin

We report a case of aggressive angiomyxoma in ischiorectal fossa of a 39-year-old women. The tumor is characterized by relatively large size(13 x 11 cm), grossly gelatinous appearance and locally infiltrative nature. Microscopically, it consists of many variable sized blood vessels and spindle or stellate cells widely separated in myxoid or collagenous stroma. Immunohistochemical stains reveal that the tumor cells are strongly positive for actin and desmin. Electron microscopic findings are that of a few cells dispersed in abundant intercellular substance and collagen bundles. These cells form irregular cytoplasmic process without basal lamina and contain endoplasmic reticulum having cistern.
Female ; Humans

To know the correlation between glomerular and tubulointerstitial lesion and to define the characteristics of interstitial inflammatory cell in IgA nephropathy and classified according to WHO classification and graded tubulointerstitial lesion as mild, moderate and severe. Paraffin-embedded 5u sections were stained with UCHL-l, L26 and CD68 antibodies. More than 20 fields were examined in each case under the high power microscopy and the number of positive cells were counted. There was positive correlation between the severity of glomerular and that of tubulointerstitial lesion. The mostcommoninflammatory cells in the interstitiuin were UCHL-l positive cells followed by CD68 and L26 positive cells. As the WHO grade or tubulointerstitial lesion increased, the numbers of positive cells were increased in all three groups. The proportion of UCHL-1 Positive cells were increased in cases with high WHO grade whereas that of L26 positive cells incases with severe tubulointerstitial lesion Proteinuria was correlated with the degree of inflammatory cell infiltration, especially with that of L26 positive cells.

Pupose:Recently childhood obesity is increasing and has been accompanied by an increase in the prevalence of type 2 diabetes mellitus(DM) among children and adolescents. We evaluated insulin resistance and impaired glucose tolerance(IGT) in 48 obese children and adolescents. METHODS:All subjects underwent a two-hour oral glucose tolerance test(1.75 g of glucose per kg of body weight) and then glucose and insulin levels were measured. Insulin resistance was estimated by homeostatic model assessment, and betacell function was estimated by calculating the ratio between the changes in the insulin level and glucose level during the first 30 minutes after the ingestion of glucose. RESULTS:IGT was detected in 4.2% of the 24 obese children(4-10 years of age) and 20.8% of the 24 obese adolescents(11 to 18 years of age). Type 2 DM was identified in 8.3% in children and 29.2% in adolescent obesity. Insulin levels were markedly elevated after the glucose tolerance test in subjects with IGT but a little decreased in cases with DM. Those changes of insulin levels were not significant statistically. The insulinogenic index was decreased in IGT and DM group of childhood and adolescent obesity compared to normal glucose tolerance(NGT) but it was not significant statistically. Insulin resistance, which was evaluated with fasting insulin, QUICKI and HOMA-IR, was increased in childhood obesity compared with adolescent obesity and the HOMA-IR of adolescent IGT group was significantly higher compared with NGT group(P<0.05). CONCLUSION: IGT is highly prevalent among children and adolescents with obesity. IGT was associated with insulin resistance and hyperinsulinemia, while beta-cell function was still relatively preserved. Overt type 2 diabetes was linked to insulin resistance and to beta cell failure.
Adolescent* ; Child* ; Eating ; Fasting ; Glucose Tolerance Test ; Glucose* ; Humans ; Hyperinsulinism ; Insulin Resistance* ; Insulin* ; Obesity* ; Pediatric Obesity ; Prevalence*

Pupose:Recently childhood obesity is increasing and has been accompanied by an increase in the prevalence of type 2 diabetes mellitus(DM) among children and adolescents. We evaluated insulin resistance and impaired glucose tolerance(IGT) in 48 obese children and adolescents. METHODS:All subjects underwent a two-hour oral glucose tolerance test(1.75 g of glucose per kg of body weight) and then glucose and insulin levels were measured. Insulin resistance was estimated by homeostatic model assessment, and betacell function was estimated by calculating the ratio between the changes in the insulin level and glucose level during the first 30 minutes after the ingestion of glucose. RESULTS:IGT was detected in 4.2% of the 24 obese children(4-10 years of age) and 20.8% of the 24 obese adolescents(11 to 18 years of age). Type 2 DM was identified in 8.3% in children and 29.2% in adolescent obesity. Insulin levels were markedly elevated after the glucose tolerance test in subjects with IGT but a little decreased in cases with DM. Those changes of insulin levels were not significant statistically. The insulinogenic index was decreased in IGT and DM group of childhood and adolescent obesity compared to normal glucose tolerance(NGT) but it was not significant statistically. Insulin resistance, which was evaluated with fasting insulin, QUICKI and HOMA-IR, was increased in childhood obesity compared with adolescent obesity and the HOMA-IR of adolescent IGT group was significantly higher compared with NGT group(P<0.05). CONCLUSION: IGT is highly prevalent among children and adolescents with obesity. IGT was associated with insulin resistance and hyperinsulinemia, while beta-cell function was still relatively preserved. Overt type 2 diabetes was linked to insulin resistance and to beta cell failure.
Adolescent* ; Child* ; Eating ; Fasting ; Glucose Tolerance Test ; Glucose* ; Humans ; Hyperinsulinism ; Insulin Resistance* ; Insulin* ; Obesity* ; Pediatric Obesity ; Prevalence*