1.The Effect of Piezoelectric Extracorporeal Shock Wave on Immature Rat Testis.
Dong Kyu LEE ; Bong Cheol SEOK ; Sung Hak SUNG
Korean Journal of Urology 1998;39(6):542-545
PURPOSE: The extent of ESWL(Extracorporeal Shock Wave Lithotripsy), a treatment for urinary calculus, shows gradual development and the treatment has become generally known as a noninvasive, safe, and efficacious method. Although the testicular effects are not within the vicinity of shock waves in carrying ESWL as a treatment for urinary calculus, research was initiated to examine effects which shock waves might cause on the testis. MATERIALS AND METHODS: After applying shock waves at intensity 4 for 1,000 times to the testis of Sprague Dawley immature rat, the histopathologic changes within the tissue of testis were observed after 1, 7, 14, 28 days, respectively. RESULTS: In the case of the experimental group having shock waves on the testis, destruction of seminiferous tubules, necrosis, and hemorrhage were found out a%or a day. One week later the atrophy of seminiferous tubules, interstitial fibrosis, and a small portion of chronic inflammatory cell appeared The capillary proliferation near the testis capsule also appeared. Two weeks later somewhat atrophied seminiferous tubules and proliferation of Leydig cells appeared. Diversely atrophied seminiferous tubules, diffusion of Leydig cell proliferation, calcified tubules, and foreignbody reaction were discovered after 4 weeks. As times went on, the tendency of recovery appeared. CONCLUSIONS: Noxious influences such as testicular atrophy and disturbance of spermatogenesis occurred in inflicting immediate shock wave on the testis. Therefore the need of more researches concerning long-term sequelae and the influences on the human body should be taken into consideration.
Animals
;
Atrophy
;
Capillaries
;
Cell Proliferation
;
Diffusion
;
Fibrosis
;
Hemorrhage
;
Human Body
;
Leydig Cells
;
Male
;
Necrosis
;
Rats*
;
Seminiferous Tubules
;
Shock*
;
Spermatogenesis
;
Testis*
;
Urinary Calculi
2.The Role of Ultrasonography in Blunt Testicular Trauma.
Sung Hwan LEE ; Bong Cheol SEOK ; Sung Hak YANG
Korean Journal of Urology 1996;37(11):1308-1312
The ultrasonographic features in 26 cases of blunt testicular trauma were reviewed. Ultrasonography diagnosed correctly in 11 surgically proven cases of testicular rupture. There were three false-positive cases, two with a large scrotal hematocele and one with epididymis rupture. there were no false-negative cases. The sensitivity and specificity of ultrasonographic diagnosis were 100% and 80% respectively. The positive and negative predictive values were 78. 6% and 100% respectively. Therefore, the negative diagnosis by ultrasonography can warrant conservative therapy.
Diagnosis
;
Epididymis
;
Hematocele
;
Male
;
Rupture
;
Sensitivity and Specificity
;
Ultrasonography*
3.Arterial Embolization for Management of Hemoptysis.
Sung Min KIM ; Young Ju KIM ; Ki Joon SUNG ; Hak Seok YANG ; Myung Sub LEE
Journal of the Korean Radiological Society 1994;30(6):1029-1034
PURPOSE: Our purpose in this study is to evaluate the effectiveness of bronchial and nonbronchial systemic arteries for the control of hemoptysis. MATERIALS AND METHODS: Seventy patients with massive or recurrent hemoptysis underwent percutaneous transcatheter embolotherapy between 1991 and 1993. Retrospectively we reviewed 77 cases of bronchial artery embotization and 32 cases of nonbronchial systemic artery embolization in the 70 patients. RESULTS: Immdiate control of hemoptysis was achieved in 33 of 39 patients with massive hemoptysis(84.6%) and 20 of 24 patients with recurrent hemopt ysis(83.3%). In 32 cases, nonbronchial systemic arteries contributed significantly to areas of pathologic pulmonary tissue and frequently were the major arterial supply. CONCLUSION: Bronchial artery embolization is an effective and life saving procedure in non-surgical candidates. Recognition and occlusion of nonbronchial systemic arteries that feed to hypervascular pulmonary lesions is essential for successful percutaneous embolotherapy of hemoptysis.
Arteries
;
Bronchial Arteries
;
Embolization, Therapeutic
;
Hemoptysis*
;
Humans
;
Retrospective Studies
4.Pelvic Fistulas Complicating Pelvic Surgery or Diseases: Spectrum of Imaging Findings.
Sung Gyu MOON ; Seung Hyup KIM ; Hak Jong LEE ; Min Hoan MOON ; Jae Sung MYUNG
Korean Journal of Radiology 2001;2(2):97-104
Pelvic fistulas may result from obstetric complications, inflammatory bowel disease, pelvic malignancy, pelvic radiation therapy, pelvic surgery, or other traumatic causes, and their symptoms may be distressing. In our experience, various types of pelvic fistulas are identified after pelvic disease or pelvic surgery. Because of its close proximity, the majority of such fistulas occur in the pelvic cavity and include the vesicovaginal, vesicouterine, vesicoenteric, ureterovaginal, ureteroenteric and enterovaginal type. The purpose of this article is to illustrate the spectrum of imaging features of pelvic fistulas.
Bladder Fistula/diagnosis/etiology
;
Female
;
Fistula/*diagnosis/*etiology
;
Human
;
Intestinal Fistula/diagnosis/etiology
;
*Pelvis
;
Ureteral Diseases/diagnosis/etiology
;
Urinary Fistula/diagnosis/etiology
;
Uterine Diseases/diagnosis/etiology
;
Vaginal Fistula/diagnosis/etiology
5.A clinical study on varicella zoster virus infection and treatment in children with malignant lymphoproliferative disease.
Hak Won KIM ; Jae Won OH ; Sung Hee OH ; Ha Baik LEE ; Hahng LEE
Journal of the Korean Pediatric Society 1991;34(9):1246-1254
No abstract available.
Acyclovir
;
Chickenpox*
;
Child*
;
Herpesvirus 3, Human*
;
Humans
6.Treatment of dystrophic scoliosis in neurofibromatosis.
Se Il SUK ; Choon Ki LEE ; Ji Ho LEE ; Hak Jin MIN ; Sung Soo CHUNG
The Journal of the Korean Orthopaedic Association 1992;27(4):956-962
No abstract available.
Neurofibromatoses*
;
Scoliosis*
7.A Study on Depression in College Students.
Jong Bum LEE ; Byung Tak PARK ; Sung Douk CHEUNG ; Jong Hak CHUNG
Yeungnam University Journal of Medicine 1985;2(1):123-132
The authors studied depression in 5,869 college students (male: 3,893, female: 1,976) using Zung's Self-Rating Depression Scale (SDS). The results are as follows: 1) Female college students showed significantly higher total depression scores than male college students (p<0.001). 2) The items of confusion, indecisiveness, and psychomotor retardation were scored higher in both groups and the items of suicidal rumination, psychomotor agitation, constipation and tachycardia were scored lower in both groups. 3) 18.2% of male college students showed rather serious depression level of score 50 or higher, while 33.1% of female college students showed the same scores. 4) The psychosocial factors relating to pessimistic views to past, present & future self-images showed significantly high depression scores. 5) The depression items of fatigue, anxiousness, tachycardia, apprehension, fear, and body aches & pain were correlated significantly over 0.40 of correlation coefficient.
Constipation
;
Depression*
;
Fatigue
;
Female
;
Humans
;
Male
;
Psychology
;
Psychomotor Agitation
;
Tachycardia
8.A Study on Anxiety in College Students.
Byung Tak PARK ; Jong Bum LEE ; Sung Douk CHEUNG ; Jong Hak CHUNG
Yeungnam University Journal of Medicine 1985;2(1):113-122
The authors studied anxiety, using Zung's SelfRating Anxiety Scale (SAS), in the subjects of 3,893 male and 1,976 female college students of Yeungnam University. The authors collected the reports of SAS during the periods from October to November, 1984, and applied ANOVA and ttest on the anxiety scores in order to compare them between various psychosocial factors, and sexes. The results could be summarized as follows: There was significant difference in the mean averages of total anxiety scores between male and female students; male students scored 36.92±7.07, female students scored 39.63±7.51, p<0.001. The anxiety scores relating to the items of sweating, apprehension, restlessness, insomnia, dyspnea were relatively higher in both groups. The anxiety scores in the items of paresthesias, mental disintegration, tremors, faintness, dizziness were lower in both groups. Two hundred and one male students (5.2%) showed seriously high anxiety scores of 50 or higher, while 201 female students (10.2%) showed the same scores. So the authors inferred that the features of anxiety symptoms were much the same in our country, but females showed more various symptoms and higher level of anxiety than males. In a comparison between male students in different school grades, freshmen showed the highest level of anxiety scores and as the grades of the students became higher, the levels of anxiety scores were lower. The female students who resided in dormitory or other residences, and whose educational fees were paid by brothers or sisters, showed higher level of anxiety scores. There was s strong tendency toward higher anxiety scores in the students who were dissatisfied with their colleges or departments, and who had pessimistic views of self-image in the past, present, or future, in both groups.
Anxiety*
;
Dizziness
;
Dyspnea
;
Fees and Charges
;
Female
;
Humans
;
Male
;
Paresthesia
;
Psychology
;
Psychomotor Agitation
;
Siblings
;
Sleep Initiation and Maintenance Disorders
;
Sweat
;
Sweating
;
Tremor
9.A Case of Chylous Ascites.
Sung Ho CHUN ; Yeon Sang LEE ; Jung Ju KIM ; Dong Hak SHIN
Journal of the Korean Pediatric Society 1982;25(12):1280-1284
No abstract available.
Chylous Ascites*
10.Effect of N-Acetylcysteine on the Superoxide Release, Chemotaxis from the Neutrophils and Glutathione Level of Plasma and Neutrophils.
Jeong Sup SONG ; Sook Young LEE ; Hwa Sik MOON ; Sung Hak PARK
Tuberculosis and Respiratory Diseases 1994;41(5):475-483
BACKGROUND: N-acetylcysteine(ACE) is used both orally and intravenously in a variety of experimental pathologies resembling human disease states which exhibit endothelial toxicity as a result of oxidative stress, including acute pulmonary oxygen toxicity, septicemia and endotoxin shock. Despite these observations in vivo, it is not certain how this thiol drug produces its protective effects. ACE is a cysteine derivative which is able to directly react with oxygen radicals and may also act as a cysteine and glutathione(GSH) precursor following deacetylation. In this paper, we tried to know whether the therapeutic doses of ACE can modify the inflammatory function of the neutrophils and can increase the glutathione level of plasma in chronic obstructive pulmonary disease(COPD) patients. In addition, the effect of ACE to the purified neutrophil in terms of superoxide release and glutathione synthesis were observed. METHOD: Firstly, we gave 600mg of ACE for seven days and compare the release of superoxide, luminol-enhanced chemiluminescence from the neutrophils, neutrophil chemotaxis, and plasma GSH levels before and after ACE treatment in COPD patients. Secondly, we observed the dose dependent effect of ACE to the purified neutrophil's superoxide release and GSH levels in vitro. RESULTS: 1) Usual oral therapeutic doses(600mg per day) of ACE for seven days did affect neither on the neutrophils superoxide release, chemiluminescence, chemotaxis, nor on the plasma GSH concentration in the COPD patients. 2) ACE decreases the purified neutrophil's superoxide release and increase the GSH production in dose dependent fashion in vitro. CONCLUSION: Despite the fact that oral ACE treatment did not affect on the neutrophil's inflammatory function and plasma GSH concentration in COPD patients in usual therapeutic doses, it decreases the superoxide release and increases the GSH production from the isolated neutrophils in high molar concentrations. These findings suggest that to obtain an antioxidative effects of ACE, it might be needed to increase the daily dosage of ACE or therapeutic duration or change the route of adminisration in COPD patients.
Acetylcysteine*
;
Chemotaxis*
;
Cysteine
;
Glutathione*
;
Humans
;
Luminescence
;
Molar
;
Neutrophils*
;
Oxidative Stress
;
Oxygen
;
Pathology
;
Plasma*
;
Pulmonary Disease, Chronic Obstructive
;
Reactive Oxygen Species
;
Sepsis
;
Shock
;
Superoxides*