Weber-Christian disease is a relapsing, febrile, nodular, nonsuppurative inflammation of the subcutaneous fat tissue. Many authors reported these cases which illustrate the great variability of the clinical manifestation, such as acute or chronic, fulminating or transient, febrile or non febrile, systemic or cutaneous. Two of our cases have had recurrent painful subeutaneous nodules without fever for several years. Biopsy showed a nonspecific inflammatory panniculitis with lymphocytes chiefly, and small amount of histiocytes and foamy cells. It should be suggested Weber-Christian disease when subcutaneous nodules appear recurrently same areas of the whole body surface except anterior aspects of tibia even if no fever as systemic manifestation. Treatment with steroid and chloroquine diphosphete produced good improvement.
Biopsy ; Chloroquine ; Fever ; Histiocytes ; Inflammation ; Lymphocytes ; Panniculitis ; Panniculitis, Nodular Nonsuppurative* ; Subcutaneous Fat ; Tibia

There is a great difference of opinion regarding the treatment of intraarticular fractures of the calcaneus. Many authors suggested that there are essentially four basic methods of treatment, but the choice of treatment depends on the surgeons preference, the type of fracture, and the age of the patient. We obtained the following results in 11 cases of calcaneal fractures involving subtalar joint which were treated by axial fixation at our hospital from 1977 to 1981. 1. The favourable results were obtained in 5 cases of 6 feet of tongue type fractures and in 3 cases of 5 feet of joint depression fractures. 2. Even if the joint depression type fracture which is not severely comminuted, the treatment with axial fixation is thought to be good method. 3. Axial fixation must be tried in three faces of reduction which are reestablishment of Bohler angle and subtalar joint and reduction of lateral bulging of calcaneus. The results were more excellent in which reduction is achieved near anatomical position.
Calcaneus ; Clinical Study ; Depression ; Foot ; Humans ; Intra-Articular Fractures ; Joints ; Methods ; Subtalar Joint ; Surgeons ; Tongue

This paper notes the effect of vasodilators on the cerebral vasospasm induced by experimental subarachnoid hemorrhage. Artificial subarachnoid hemorrhage produced by dual injection of non-heparinized autologous blood into the cisterna magna in rabbits with 72 hours interval gave rise to considerable narrowing or spasm of the basilar artery and its branches demonstrated by cerebral angiography. SAH was induced in 12 rabbits by injecting 1.3mL/kg or autologous fresh arterial blood into the cisterna magna, followed by suspending the rabbits in a head-down position at 30 degree for 1 hour in order to accumulate blood around the basilar artery. The animals were divided into 4 groups; a group receiving nifedipine, a group receiving aminophylline, a group receiving papaverine, a group receiving trifluoperazine HCl. Angiographically vertebrobasilar arterial spasm was demonstrated 3 days after the 2nd autologous blood injection into the cisterna magna. Radiographically visible spasm was resistant to the vasodilating drugs. Rabbits were sacrificed by the overdose injection of sodium phenobarbital at the end of experiment.
Aminophylline ; Angiography ; Animals ; Basilar Artery ; Cerebral Angiography ; Cisterna Magna ; Nifedipine ; Papaverine ; Phenobarbital ; Rabbits ; Sodium ; Spasm ; Subarachnoid Hemorrhage* ; Trifluoperazine ; Vasodilator Agents* ; Vasospasm, Intracranial*

No abstract available.
Humans ; Risk Factors*

No abstract available.
Humans

PURPOSE: Ginkgo biloba extract (GBE) is known to increase the peripheral blood circulation. This study was designed to evaluate the effect of GBE on the acute normal tissue radiation reaction. MATERIALS AND METHODS: C3H mice were divided into two groups, radiation alone and two doses GBE plus radiation, for both acute skin reaction and jejunal crypt assay. GBE was given i.p. one hour before irradiation with priming dose given one day earlier. Thirty to Fifty Gy for acute skin reaction and 11 to 14 Gy for jejunal crypt were irradiated to right hind leg and whole body, respectively. RESULTS: Radiation doses (RD50) for peak skin score of 2.0 were 44.2Gy (40.6-48.2Gy) for radiation alone and 44.4Gy (41.6-47.4Gy) for two doses GBE plus radiation, showing no effect of GBE on acute radiation skin damage. The numbers of regenerating jejunal crypts per circumference were also almost the same for each radiation dose level (p=0.57-0.94), and the mean lethal doses (Do) were 1.80Gy (1.57-2.09Gy) for radiation alone and 1.88Gy (1.65-2.18Gy) for two doses GBE plus radiation, indicating no effect of GBE on jejunal crypt cell survival after radiation. CONCLUSION: GBE doesn't increase acute normal tissue radiation reaction in this model system. As GBE was verified to enhance radiation effect on tumor, high therapeutic gain is expected when GBE is combined with radiation therapy.
Animals ; Blood Circulation ; Cell Survival ; Ginkgo biloba* ; Leg ; Mice* ; Mice, Inbred C3H ; Radiation Effects ; Radiation Tolerance* ; Skin*

PURPOSE: Ginkgo biloba extract (GBE) is known to increase the peripheral blood circulation. This study was designed to evaluate the effect of GBE on the acute normal tissue radiation reaction. MATERIALS AND METHODS: C3H mice were divided into two groups, radiation alone and two doses GBE plus radiation, for both acute skin reaction and jejunal crypt assay. GBE was given i.p. one hour before irradiation with priming dose given one day earlier. Thirty to Fifty Gy for acute skin reaction and 11 to 14 Gy for jejunal crypt were irradiated to right hind leg and whole body, respectively. RESULTS: Radiation doses (RD50) for peak skin score of 2.0 were 44.2Gy (40.6-48.2Gy) for radiation alone and 44.4Gy (41.6-47.4Gy) for two doses GBE plus radiation, showing no effect of GBE on acute radiation skin damage. The numbers of regenerating jejunal crypts per circumference were also almost the same for each radiation dose level (p=0.57-0.94), and the mean lethal doses (Do) were 1.80Gy (1.57-2.09Gy) for radiation alone and 1.88Gy (1.65-2.18Gy) for two doses GBE plus radiation, indicating no effect of GBE on jejunal crypt cell survival after radiation. CONCLUSION: GBE doesn't increase acute normal tissue radiation reaction in this model system. As GBE was verified to enhance radiation effect on tumor, high therapeutic gain is expected when GBE is combined with radiation therapy.
Animals ; Blood Circulation ; Cell Survival ; Ginkgo biloba* ; Leg ; Mice* ; Mice, Inbred C3H ; Radiation Effects ; Radiation Tolerance* ; Skin*

Recently the rate of adolescent smoking in Korea has increased rapidly, and various health problems related to smoking can be expected to increase in the future. Studies on smoking behavior report that assertiveness is important factor influencing on the adolescent smoking. PURPOSE: This study was conducted to develope a educational video for the purpose of adolescent's smoking prevention. METHOD: The 533 participating subjects, 269 in experimental group and 264 control group, in the study were 7th grade students. The content of video introduces three smoke tempting situations. The experimental group received 17 minute video education, and the control group did not receive any treatments. RESULT: The results show that the student's assertiveness was increased significantly in the experimental group after the video education. Student's attitude on smoking became more negative in the experimental group. However, in the control group, the intention, assertiveness, attitude was not changed. CONCLUSION: This assertiveness video can be useful educational resource for the smoking prevention program for adolescents. Also further study on longitudinal effect and application on drinking, drug abuse are needed.
Adolescent* ; Assertiveness ; Drinking ; Education ; Humans ; Intention ; Korea ; Smoke* ; Smoking* ; Substance-Related Disorders

The time course of recovery in vestibular neuritis varies between individuals. The aim of this study was to identify the predictors for the early or late recovery of vestibular neuritis. The inclusion criteria were patients 1) who had an acute onset of vertigo lasting at least 24 hours, 2) with a horizontal-torsional unidirectional spontaneous nystagmus, and 3) with a canal paresis of 20% or more on the bithermal caloric tests. The primary endpoint for this study was an early or late recovery of vestibular neuritis as a dependent variable. A functional level scale was used to define the late recovery (5 or more points) at seven days after the symptom onset. The secondary endpoint was the duration of hospitalization. One hundred twenty eight patients met the inclusion criteria for this study, and among them, 71 patients had an early recovery. Multiple logistic regression analysis showed that diabetes mellitus was the only independent significant variable for the prediction of a late recovery of vestibular neuritis. In addition, the diabetes mellitus was a predicting variable for long duration of hospitalization. Diabetes mellitus was a predictor for a late recovery of vestibular neuritis.

We have experienced a rare case of multiple intracranial aneurysms associated with polycystic kidney and polycystic liver, which were incidental findings after minor leakage. A 57-year-old female was admitted with the chief complaint of severe headache under the impression of subarachnoid hemorrhage due to rupture of the intracranial aneurysm(which were appeared as the right middle cerebral artery and A-com aneurysm). The brain CT scan showed subarachnoid hemorrhage in the right sylvian fissure and the right temporal lobe. On physical examination, 2FB hard irregular palpable mass was noted on the right costal margin. On neurological examination, her neck was mildly stiff and other signs were within normal limit. We checked abdominal sonography, abdominal CT scan and carotid angiography preoperatively, and reviewed the literature about polycystic disease associated with intracranial aneurysm and discussed about it.
Angiography ; Brain ; Female ; Headache ; Humans ; Incidental Findings ; Intracranial Aneurysm* ; Liver ; Middle Aged ; Middle Cerebral Artery ; Neck ; Neurologic Examination ; Physical Examination ; Polycystic Kidney Diseases ; Rupture ; Subarachnoid Hemorrhage ; Temporal Lobe ; Tomography, X-Ray Computed